Development of functional somatosensory circuits in the human infant brain

Lead Research Organisation: University College London
Department Name: Neuroscience Physiology and Pharmacology

Abstract

Our senses are essential for interpreting and interact with the world around us. The brain has specialised areas dedicated to decoding different stimuli and allowing us to distinguish between a light touch, a firm squeeze or a sharp needle. However, how the brain acquires these capabilities and when, during development, remains unclear. The brain of a newborn, especially if premature, is not merely a down-sized version of that of an adult, but has different structures and functions that can change week by week in an adaptable way. Some of these early changes are necessary for the maturation of the brain, while some, especially those caused in prematurity by stimuli that do not naturally occur in the womb, may be detrimental. I plan to explore the maturation of sensory functions in premature infants. In particular, I will study the developing human brain in order to understand how we normally learn to feel different sensations and, how this is affected by prematurity and subsequent experience in intensive care. The results will contribute to fundamental knowledge of the developing human brain and help to establish methods of ensuring healthy brain maturation in premature infants.

Technical Summary

I intend to establish a London based research program to study the mechanisms underlying the formation of early somatosensory cortical networks and the role of spontaneous and evoked neuronal activity in the developing human infant brain. The work will be cross-disciplinary involving neurophysiology, imaging, statistical analysis and neonatology at UCL, King's College London and their hospitals. I plan to record non-invasive electrophysiological activity (EEG) and the structural and functional brain correlates (MRI and fMRI) in premature and term infants of 28-42 weeks corrected gestational age in the neonatal units at UCLH and St Thomas' Hospital. I will: (i) compare the development of the EEG signal at rest with the structural and functional MRI within the same infants to establish the involvement of developing brain structures in generating the endogenous neuronal activity responsible for the initial formation of the somatosensory cortical circuits; (ii) compare the scalp topography and related cortical functional activation of different activity patterns to establish how early spontaneous and somatosensory-evoked activity shape and refine local and global cortical networks; (iii) explore the emerging organization of the somatosensory cortical maps using fMRI and sensory evoked potentials ; (iv) study the effect of early postnatal intensive care experience upon the development of cortical somatosensory function.

Planned Impact

The primary beneficiaries will be preterm and term infants which are exposed to excessive somatosensory stimulation as part of their clinical care during a very critical period in their development.
The rate of premature births is rising in many European countries and especially in the UK, where the number of babies born at 22-25 weeks gestation and admitted to intensive care increased by 44% between 1995 and 2006. At the same time, the survival rates of these infants have increased thanks to recent advances in perinatal care, however are exposed to a greater risk of neurodevelopmental impairments, and long-term adverse outcomes. A better understanding and monitoring of the developmental trajectory of brain function in prematurity is therefore important in order to target these issues. This project will provide new insight into somatosensory processing in this group of individuals and provide a platform for studies of different neuroprotective interventions or pharmacologic agents and better patient care.
Clinicians responsible for the care of these infants will also benefit from this research: neonatologists, paediatricians, paediatric anaesthetists and all health professionals involved in the management and treatment of premature infants will have a better scientific basis upon which to devise their hospital care.
Families of these infants will benefit from an increased understanding and interest in what their babies are experiencing and the drive towards better clinical care.
In the longer term, there will be economic benefits for society in general. Increasing evidence suggests that abnormalities in the brain developmental trajectory of preterm-born infants persist through adulthood. Perinatal brain injuries or more subtle disturbances in brain maturation may underlie the development of major motor disabilities, such as cerebral palsy, and impairment of cognitive, language and social functions. Infants who are born too young or too small and who have to spend time in intensive care will therefore benefit from this research, not only at the time but also in later life. The increased understanding of how the brain processes external inputs in early life in individual infants will not only lead to better treatment and management of this vulnerable group, but also have long term benefits in terms of better health and therefore quality of life over their whole lifespan. Considering that neurodevelopmental and cognitive disabilities are a huge financial burden on society in terms of educational support and the provision of care, better health outcomes for a growing subset of the population will also potentially have a large impact on society as a whole, helping to relieve this burden.
Neuroimaging protocols, especially combining multimodal imaging techniques, could ultimately identify biomarkers to be targeted therapeutically. Moreover, neuroimaging will have an invaluable screening scope in identifying those individuals at higher risk of abnormal neurodevelopment.
 
Title Art Neuro 
Description As part of the Art Neuro initiative Dr Madeleine Verriotis and I have teamed up with illustrator Martina Paukova to produce an illustration depicting the the atmosphere of the day-to-day working environment in our laboratory. The initiative intended to explore the world of neuroscience through the visual arts to provide an exciting, thought-provoking and unique visual experience. 
Type Of Art Artwork 
Year Produced 2014 
Impact The exhibition was very successful attracting the attention of audiences and press ( including The Guardian and Time Out) 
URL http://www.artneuro.co.uk/
 
Description Research Associate of the grant has joined the Affiliate Working Group of the UK Physiological Society
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
Impact The Affiliate Working Group has been set up to promote the education and progression of early career scientists. Its recommendations affect Physiological Society policy, such as the use of quotas to increase the proportion of early career researchers speaking at national conferences.
URL http://www.physoc.org/affiliate-working-group
 
Description Brain injuries acquired during the neonatal period: investigating mechanisms which can correct depressed cortical electrical activity
Amount £298,114 (GBP)
Funding ID 201819-23 
Organisation Brain Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2020 
End 04/2023
 
Description Doctoral School Bursary for Kimberley Whitehead to attend the Cheltenham Science Festival 2017 (to learn from high quality public engagement)
Amount £600 (GBP)
Organisation University College London 
Sector Academic/University
Country United Kingdom
Start 05/2017 
End 06/2017
 
Description Grand Challenges - awarded to Kimberley Whitehead
Amount £3,862 (GBP)
Organisation University College London 
Sector Academic/University
Country United Kingdom
Start 08/2017 
End 07/2018
 
Description MRC Confidence in Concept and UCLH Biomedical Research Centre's portion of the UCL Therapeutic Acceleration Support Fund; PI: Kimberley Whitehead (will cover her personal salary from April 2019), Co-I: Lorenzo Fabrizi
Amount £69,389 (GBP)
Organisation University College London 
Sector Academic/University
Country United Kingdom
Start 03/2019 
End 04/2020
 
Description Medical Research Foundation Emerging Leaders Prize 2020 Pain Research
Amount £100,000 (GBP)
Funding ID MRF-160-0012-ELP-FABR-C0841 
Organisation Medical Research Council (MRC) 
Department Medical Research Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 04/2021 
End 11/2022
 
Description Public Engagement Grant - awarded to Kimberley Whitehead
Amount £200 (GBP)
Organisation Physiological Society 
Sector Charity/Non Profit
Country Global
Start 02/2018 
End 02/2018
 
Description Research Grant
Amount £1,108,804 (GBP)
Funding ID MR/M006468/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 08/2014 
End 08/2018
 
Description SLMS Graduate External Training Courses Fund Application
Amount £251 (GBP)
Organisation University College London 
Department School of Life and Medical Sciences
Sector Academic/University
Country United Kingdom
Start 03/2016 
End 04/2016
 
Description SLMS Graduate Student Conference Fund Application
Amount £125 (GBP)
Organisation University College London 
Department School of Life and Medical Sciences
Sector Academic/University
Country United Kingdom
Start 05/2017 
End 06/2017
 
Description The developing human pain connectome and brain dynamics of infant pain: sex differences, pain history and skin-to-skin care
Amount £949,354 (GBP)
Funding ID MR/S003207/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 11/2018 
End 10/2022
 
Description Travel Grant
Amount £307 (GBP)
Organisation Guarantors of Brain 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2016 
End 06/2016
 
Description Travel Grant - awarded to Kimberley Whitehead
Amount £500 (GBP)
Organisation Physiological Society 
Sector Charity/Non Profit
Country Global
Start 04/2018 
End 05/2018
 
Description Travel grant from Association of Neurophysiological Scientists
Amount £500 (GBP)
Organisation Association of Neurophysiological Scientists 
Sector Learned Society
Country United Kingdom
Start 04/2018 
End 05/2018
 
Description University College London Global Engagement fund
Amount £1,997 (GBP)
Organisation University College London 
Sector Academic/University
Country United Kingdom
Start 04/2019 
End 05/2019
 
Title New MRI compatible EEG caps 
Description Dr Arichi and I in collaboration with Brain Product have developed a new EEG cap to allow minimization of MR artefact caused by the EEG electrode on the scalp of the subject. This new design inlcude the use of a new conductive polymer. 
Type Of Material Improvements to research infrastructure 
Year Produced 2019 
Provided To Others? No  
Impact This new cap will allow simultaneous EEG-fMRI data collection minimizing the interference between the two modalities. 
 
Title Simultaneous neonatal EEG-fMRI 
Description Dr Arichi and I have pioneered the use of simultaneous EEG-fMRI to assess the link between electrophysiological and haemodynamic brain functions in premature neonates. This menthod was already successfully applied to adults. 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2017 
Provided To Others? No  
Impact This new technique opens new avenues to understand the relationship between the neuronal patterns that characterise the developing premature brain and the underlying brain functional activity. 
 
Title Neonatal Brain Models 
Description We have established a close collaboration with Dr R Cooper from UCL Medical Physics to develop a neonatal brain model for functional imaging of the neonatal brain that is freely available online. 
Type Of Material Computer model/algorithm 
Year Produced 2021 
Provided To Others? Yes  
Impact This is the first available neonatal head model for EEG/EMG source reconstruction in neonates and NIRS tomography 
URL http://www.ucl.ac.uk/dot-hub
 
Title Neonatal Somatosensory Event Related Potentials following stimulation of the face with 'glove' stimulator - open access datasets 
Description Neonatal Somatosensory Event Related Potentials acquired with gentle 'glove' stimulator (the other datasets were acquired with a small modified tendon hammer, unsuitable for stimulation of the face). 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact This research database allowed us to validate our new 'glove' stimulator, which is an improvement on our previous stimulator because it allows to stimulate the delicate facial area. The datasets are included as supplementary material with our PLOS ONE paper (doi below). 
 
Title Neonatal Somatosensory Event Related Potentials following stimulation of the limbs 
Description 70 datasets total (as of February 2019). 34 datasets of somatosensory Event Related Potentials in healthy neonates with no requirement for respiratory support 34-42 weeks Post Menstrual Age in response to a gentle tap of the four limbs (data analysis published in Cerebral Cortex 2019). 29 datasets of somatosensory Event Related Potentials in neonates at low risk of adverse development aged 28-34 weeks Post Menstrual Age in response to a gentle tap of the four limbs (excluded from Cerebral Cortex 2019 paper because too young or required respiratory support). Seven datasets (seven recordings from six unique subjects) of somatosensory Event Related Potentials in neonates with large germinal matrix-intraventricular hemorrhage 31-35 weeks Post Menstrual Age in response to a gentle tap of the four limbs (manuscript in preparation). Data were collected at the University College London Hospital, London, NW1 2BU, UK. 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? No  
Impact This database will help us to understand the development of the somatosensory representation of the body in prematurity and the meaning of the electrical activity recorded from the brain following somatosensory stimulations. 
 
Title Neonatal resting EEG 
Description 214 datasets (as of February 2019) of resting EEG in neonates 28-47 weeks Post Menstrual Age collected at the University College London Hospital, London, NW1 2BU, UK. 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? No  
Impact This data will improve our understanding of the development of spontaneous activity occurring in prematurity. This has not been quantitatively described yet and could provide normative value against which individual recording could be compared to. 
 
Title Neonatal resting EEG-fMRI 
Description 13 datasets of simultaneous resting EEG-fMRI 7.5-12.5 minutes long in premature neonates (32-36 weeks post-menstrual age) collected at the Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, St Thomas' Hospital, London, SE1 7EH, UK 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact This is the first time that this kind of data have ever been collected. This data will improve our understanding of the link between the neuronal patterns that characterise the developing premature brain and the underlying brain functional activity 
URL https://brain-development.org/activation-maps-related-to-spontaneous-delta-brush-activity/
 
Description Boston Childrens' Hospital 
Organisation Boston Children's Hospital
Country United States 
Sector Hospitals 
PI Contribution Description: This is a new collaboration with Dr Christos Papadelis from Boston Childrens' Hospital. Main purpose of this collaboration: source localization of somatosensory evoked EEG activity in the preterm brain. My contributions to this partnership are: - Intellectual input: partecipation to discussion and knowledge exchange and generation of new biological questions - Expertise in neonatal EEG aquisition - Expertise in neonatal EEG processing
Collaborator Contribution The contributions made by Dr Papadelis is: - Expertise in EEG source localization and Boundary Element Model forming
Impact This collaboration is multi-disciplinary and involves: neurophysiology, neonatology, signal processing. Current Outputs: Research Articles: Whitehead K., et al. (accepted for publication in Cerebral Cortex)
Start Year 2018
 
Description Brain Products and KCL 
Organisation Brain Products
Country Germany 
Sector Private 
PI Contribution Description: This is a collaboration with an industrial partner. Main purpose of this collaboration: develop MRI compatible neonatal EEG electrodes My contributions to this partnership are: - Intellectual input: partecipation to discussion and knowledge exchange - Expertise in neonatal EEG-fMRI aquisition - Expertise in neonatal EEG processing - Study design - Data collection and analysis
Collaborator Contribution The contributions made by KCL are: - Intellectual input: partecipation to discussion and knowledge exchange - Expertise in MRI physics - Access to MRI scanner - Study design - Data collection and analysis The contributions made by Brain Products are: - Intellectual input: partecipation to discussion and knowledge exchange - Electrode design and manufacturing - Study design
Impact This collaboration is multi-disciplinary and involves: neonatology, EEG, brain imaging, engineering, product design. Current Outputs: User research article published on the Brain Products website (https://pressrelease.brainproducts.com/eeg-fmri-preterm-humans/) and design of new MRI compatible EEG caps to minimise image artefacts and compatible with Rapid MRI aquisition coil. The design of the new cap involved various iteractions and visits by company representatives.
Start Year 2014
 
Description Brain Products and KCL 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Description: This is a collaboration with an industrial partner. Main purpose of this collaboration: develop MRI compatible neonatal EEG electrodes My contributions to this partnership are: - Intellectual input: partecipation to discussion and knowledge exchange - Expertise in neonatal EEG-fMRI aquisition - Expertise in neonatal EEG processing - Study design - Data collection and analysis
Collaborator Contribution The contributions made by KCL are: - Intellectual input: partecipation to discussion and knowledge exchange - Expertise in MRI physics - Access to MRI scanner - Study design - Data collection and analysis The contributions made by Brain Products are: - Intellectual input: partecipation to discussion and knowledge exchange - Electrode design and manufacturing - Study design
Impact This collaboration is multi-disciplinary and involves: neonatology, EEG, brain imaging, engineering, product design. Current Outputs: User research article published on the Brain Products website (https://pressrelease.brainproducts.com/eeg-fmri-preterm-humans/) and design of new MRI compatible EEG caps to minimise image artefacts and compatible with Rapid MRI aquisition coil. The design of the new cap involved various iteractions and visits by company representatives.
Start Year 2014
 
Description GOSH - Ronit Pressler 
Organisation Sheffield Teaching Hospitals NHS Foundation Trust
Department Department of Clinical Neurophysiology
Country United Kingdom 
Sector Hospitals 
PI Contribution Description: This is a new collaboration with Dr Ronit Pressler (GOSH). Main purpose of this collaboration: study the development of spontaneous neuronal activity in premature neonates. My research team contributions to this partnership are: - Intellectual input - Expertise in quantitative EEG signal processing - Study design - Preparation of manuscripts and conference abstracts - Project Management. 2019: This collaboration has now extended beyond its initial scope and Dr Pressler is also a collaborator on a newly awarded MRC Research Grant to study the development of the human dynamic pain connectome.
Collaborator Contribution Contributions made my partners include: - Intellectual input: formulation of clinically relevant questions - Expertise in clinical EEG recording and interpretation
Impact This collaboration is multi-disciplinary and involves: clinical neurophysiology, neuroscience and signal processing. Current outputs: Published Review Article: - Whitehead K., Pressler R., Fabrizi L. (2017) Characteristics and clinical significance of delta brushes in the EEG of premature infants. Clinical Neurophysiology Practice 2: 12-18 Published Research Article: - Arichi T., Whitehead K., Barone G., Pressler R., Padormo F., Edwards A.D., Fabrizi L. (2017) Localization of spontaneous bursting neuronal activity in the preterm human brain with simultaneous EEG-fMRI. eLIFE; 6:e27814 Others: - Secondary supervisor for Ms Kimberley Whitehead - Collaborator on a new MRC funded Research Grant
Start Year 2016
 
Description KCL and ICL 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Description: This is a three-way collaboration between UCL (myself), KCL (Dr Tomoki Arichi) and ICL (Prof Etienne Burdet). Main purpose of this collaboration: adevelop new tools to allow the study of somatosensory perception in premature neonates at the cotside or in the MR environment. My contributions to this partnership are: - Intellectual input: partecipation to discussion and knowledge exchange and generation of new biological questions - Expertise in neonatal EEG aquisition - Expertise in neonatal EEG processing
Collaborator Contribution The contributions made by my partners are: - Expertise in engineering (ICL) - Expertise in designing medical devices to be used in the premature population (KCL + ICL) - Expertise in applying stimulation devices in the MR environment (KCL)
Impact This collaboration is multi-disciplinary and involves: biomedical engineering, neonatology, neuroscience, signal processing. Outputs: - Invited speaker in 2014: Pain Robotics (Imperial College London, UK) - Research Articles: Riillo F., et al. (2016) Ann Biomed Eng 44 (8), 2431-41; Donadio A., et al. (2018) Plos One 13, e0207145 - Engament Activities: press release associated with Donadio A., et al. (2018) Plos One which featured in 7 news outlets
Start Year 2015
 
Description KCL and ICL 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Description: This is a three-way collaboration between UCL (myself), KCL (Dr Tomoki Arichi) and ICL (Prof Etienne Burdet). Main purpose of this collaboration: adevelop new tools to allow the study of somatosensory perception in premature neonates at the cotside or in the MR environment. My contributions to this partnership are: - Intellectual input: partecipation to discussion and knowledge exchange and generation of new biological questions - Expertise in neonatal EEG aquisition - Expertise in neonatal EEG processing
Collaborator Contribution The contributions made by my partners are: - Expertise in engineering (ICL) - Expertise in designing medical devices to be used in the premature population (KCL + ICL) - Expertise in applying stimulation devices in the MR environment (KCL)
Impact This collaboration is multi-disciplinary and involves: biomedical engineering, neonatology, neuroscience, signal processing. Outputs: - Invited speaker in 2014: Pain Robotics (Imperial College London, UK) - Research Articles: Riillo F., et al. (2016) Ann Biomed Eng 44 (8), 2431-41; Donadio A., et al. (2018) Plos One 13, e0207145 - Engament Activities: press release associated with Donadio A., et al. (2018) Plos One which featured in 7 news outlets
Start Year 2015
 
Description KCL: EEG-fMRI 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution I have established a close collaboration with Dr Tomoki Arichi and Prof David Edwards from the Centre for the Developing Brain at King's College London. We are conducting collaborative experiments using simultaneous electrophysiology (EEG) and brain imaging (fMRI) to assess brain development in premature neonates. My research team's contributions are: - Intellectual input: the experiements are based on my design - Expertise in EEG recording: my research assistant (research clinical neurophysiologist) and I set up and run the EEG side of the data aquisition - Expertise in EEG data processing - Training in EEG skills of a consultant neonatologist from St Thomas' - Publications and conference abstracts preparation - Management of the overall project
Collaborator Contribution The Centre for the Developing Brain lead by Prof Edwards is the only centre in the UK to have an MR scanner on the neonatal intensive care unit. Here I have access to subjects and dedicated scanning time. Dr Arichi is a newly appointed Clinical Research Fellow with an exceptional experience in premature infant functional imaging. He is ensuring that the MR experiments are conducted to the best clinical standards and with the most up-to-date techniques. Other contributions made my partners are: - Intellectual input - Support from research nurses and radiographers at the time of study - Expertise in MRI/fMRI data processing and MRI images interpretation - Training in MRI/fMRI skills of my research assistant and myself
Impact This collaboration is multi-disciplinary and involves: electrophysiology (EEG), brain imaging (MRI/fMRI), neonatology, neuroscience and signal processing. Current Outputs: Publications: Arichi et al. (2017) eLife; 6:e27814. Engament Activities: press release and article for "The Conversation" (public science media outlet). Awards & Recognitions: Invited oral presentation to the 2016 Organization for Human Brain Mapping meeting in Geneva, Organization for Human Brain Mapping 2016 Merit Abstract Award, Spotlight Article in Trends in Neurosciences in 2017.
Start Year 2014
 
Description UCL Institute for Women's Health - Dr Whitehead - Perinatal Brain Injury 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Dr Whitehead was the research assistant on my MRC CDA and part-time PhD student during that time. She then obtained independent funding, moved to the UCL Institute for Women's Health and we now collaborate. We are conducting collaborative experiments investigating sleep and sensory perception in infants with perinatal brain injury. My and my research team contribution are: - Intellectual input: data discussion and interpretation - Expertise in EEG signal processing - Historical Data
Collaborator Contribution Dr Whitehead is carving herself a niche of expertise in perinatal brain injury and neonatal sleep so her contribution are: - Intellectual: the experiment/analysis are her ideas - Data collection and analysis - Management of the overall project
Impact This collaboration is multi-disciplinary and involves: electrophysiology (EEG), neuroscience of brain development, neonatology and signal processing. Current Output: Publications: https://doi.org/10.1093/sleep/zsaa148.
Start Year 2020
 
Description UCL Medical Physics - Dr Cooper - Neonatal Brain Models 
Organisation University College London
Department Department of Medical Physics and Biomedical Engineering
Country United Kingdom 
Sector Academic/University 
PI Contribution We have established a close collaboration with Dr Cooper from Medical Physics here at UCL. We have developed a neonatal brain model for functional imaging of the neonatal brain that is freely available online at www.ucl.ac.uk/dot-hub. Our contributions are: - Intellectual input: expertise in EEG and brain development - manuscript revision.
Collaborator Contribution Contributions made by Dr Cooper's group are: - Intellectual input - Model design and validation - overall project management - manuscript preparation.
Impact This collaboration is multi-disciplinary and involves: human neurophysiology, brain imaging, neonatology, neuroscience and computational modelling. The outcome is a peer review publication: Collins-Jones, LH, Arichi, T, Poppe, T, et al. Construction and validation of a database of head models for functional imaging of the neonatal brain. Hum Brain Mapp. 2021; 42: 567- 586. https://doi.org/10.1002/hbm.25242 A freely available neonatal head model for functional imaging available at www.ucl.ac.uk/dot-hub.
Start Year 2019
 
Description UCL Neuroscience - Giandomenico Iannetti 
Organisation University College London
Department Department of Neuroscience, Physiology and Pharmacology
Country United Kingdom 
Sector Academic/University 
PI Contribution Description: Collaboration with Professor Giandomenico Iannetti (UCL Neuroscience, Physiology and Pharmacology) Main purpose of this collaboration: study the development of habituation to repeated stimuli in humans. My contributions to this partnership are: - Intellectual input: partecipation to discussion and knowledge exchange - Expertise in neonatal EEG - Preparation of manuscripts
Collaborator Contribution Contributions made my partners include: - Intellectual input: partecipation to discussion and knowledge exchange - Study design - Preparation of manuscripts - Expertise in the use of EEG recording to answer cognitive questions in humans
Impact This collaboration is multi-disciplinary and involves: clinical neurphysiology, developmental neuroscience, signal processing. Current Output: Draft of research article entitled "Lack of habituation of the brain responses to transient somatosensory stimuli in infants".
Start Year 2014
 
Description UCL Neuroscience - Pishan Chang 
Organisation University College London
Department Neuroscience, Physiology & Pharmacology
Country United Kingdom 
Sector Academic/University 
PI Contribution Description: Collaboration with Professor Maria Fitzgerald and Dr Pishan Chang (UCL Neuroscience, Physiology and Pharmacology) Main purpose of this collaboration: study the development of nociception in rat models of neonatal surgery. My contributions to this partnership are: - Intellectual input: partecipation to discussion and knowledge exchange - Expertise in EEG signal processing - Development and application of ad-hoc signal processing tools - Preparation of manuscripts
Collaborator Contribution Contributions made my partners include: - Intellectual input: formulation of neuroscientific and clinically relevant questions - In-vivo animal experiments - Study design - Preparation of manuscripts
Impact This collaboration is multi-disciplinary and involves: developmental neuroscience, signal processing. Output: Research Article: Chang P., Fabrizi L., Olhede S., Fitzgerald M. (2016) The development of nociceptive network activity in the somatosensory cortex of freely moving rat pups. Cereb Cortex 26 (12): 4513-4523 Another Research Article is in preparation
Start Year 2015
 
Description UCL Neuroscience and UCLH 
Organisation University College Hospital
Department Neonatal Services Unit
Country United Kingdom 
Sector Academic/University 
PI Contribution Description: This is a long-standing collaboration with Professor Maria Fitzgerald (UCL Neuroscience, Physiology and Pharmacology) and Dr Judith Meek (UCLH) which is still active thanks to the support received by the Medical Research Council. Main purpose of this collaboration: study the development of pain perception and relationship with stress in premature neonates. My research team contributions to this partnership are: - Intellectual input - Expertise in EEG signal processing - Study design - Preparation of manuscripts and conference abstracts - Management - Training of a research nurse in applying EEG electrodes to international standards
Collaborator Contribution Contributions made my partners include: - Intellectual input: formulation of neuroscientific and clinically relevant questions - Access to patients - Study design - Staff: postdocs and research nurses
Impact This collaboration is multi-disciplinary and involves: neonatology, neuroscience, signal processing. Current Outputs: Further Fundings: MRC-UK, Research Grant (MR/M006468/1; 2014-2018 and MR/S003207/1 2018-2022). Research Articles: Verriotis M., et al. (2016). eNeuro 3, e0026-16; Fabrizi et al. (2016) Sci Rep 6, 28642; Jones L., et al. (2017). Curr Biol 27, 3846-3851; Verriotis M., et al. (2018) Neuroimage (178) 69-77; Jones L., et al. (2018) Sci Data 5, 180248 Review Article: Verriotis M., Chang P., Fitzgerald M., Fabrizi L. (2016) The development of the nociceptive brain. Neuroscience 338, 207-219
Start Year 2008
 
Description UCL Neuroscience and UCLH 
Organisation University College London
Department Neuroscience, Physiology & Pharmacology
Country United Kingdom 
Sector Academic/University 
PI Contribution Description: This is a long-standing collaboration with Professor Maria Fitzgerald (UCL Neuroscience, Physiology and Pharmacology) and Dr Judith Meek (UCLH) which is still active thanks to the support received by the Medical Research Council. Main purpose of this collaboration: study the development of pain perception and relationship with stress in premature neonates. My research team contributions to this partnership are: - Intellectual input - Expertise in EEG signal processing - Study design - Preparation of manuscripts and conference abstracts - Management - Training of a research nurse in applying EEG electrodes to international standards
Collaborator Contribution Contributions made my partners include: - Intellectual input: formulation of neuroscientific and clinically relevant questions - Access to patients - Study design - Staff: postdocs and research nurses
Impact This collaboration is multi-disciplinary and involves: neonatology, neuroscience, signal processing. Current Outputs: Further Fundings: MRC-UK, Research Grant (MR/M006468/1; 2014-2018 and MR/S003207/1 2018-2022). Research Articles: Verriotis M., et al. (2016). eNeuro 3, e0026-16; Fabrizi et al. (2016) Sci Rep 6, 28642; Jones L., et al. (2017). Curr Biol 27, 3846-3851; Verriotis M., et al. (2018) Neuroimage (178) 69-77; Jones L., et al. (2018) Sci Data 5, 180248 Review Article: Verriotis M., Chang P., Fitzgerald M., Fabrizi L. (2016) The development of the nociceptive brain. Neuroscience 338, 207-219
Start Year 2008
 
Description UCL Statistical Sciences: Sofia Olhede 
Organisation University College London
Department Department of Statistical Science
Country United Kingdom 
Sector Academic/University 
PI Contribution Description: This is a long-standing collaboration with Professor Sofia Olhede from the UCL department of Statistical Sciences which is still active thanks to the support received by the Medical Research Council. Main purpose of this collaboration: application of advanced statistical and signal processing techniques to neonatal electroencephalographic recordings. My contributions to this partnership are: - Intellectual input: formulation of clinical and neuroscientific questions - access to EEG data - Expertise in neonatal EEG - Study design - Preparation of manuscripts and conference abstracts - Management fo the overall projects
Collaborator Contribution The contributions made by Sofia Olhede are: - Expertise in statistical analysis - Expertise in advanced signal processing - Design of ad-hoc statistical and signal processing techniques
Impact This collaboration is multi-disciplinary and involves: statistical sciences, neonatology, neuroscience, signal processing. Current Outputs: Prof Olhede is a collaborator on the new MRC Research Grant (MR/S003207/1 2018-2022)
Start Year 2011
 
Title Neonatal MRI compatible EEG cap 
Description This project is in collaboration with Kings' College London and Brain Products. The aim is to develop new electrodes to record electrical activity from the premature and newborn brain (EEG) in a magnetic resonance imaging (MRI) environment. We have currently tested new materials to make the electrodes in order to minimise MRI distortion and maximise patient comfort with the intention of producing a prototype to be used in pilot studies. 2019 update. A new conductive polymer has been identified and our industrial partner (Brain Products) has developed a prototype cap that we are currently testing on phantoms. The results suggest that the artefacts caused by the EEG electrode is now reduced. 
Type Diagnostic Tool - Imaging
Current Stage Of Development Initial development
Year Development Stage Completed 2018
Development Status Under active development/distribution
Impact This project may lead to the generation of new IP surrounding the MRI compatible EEG electrode which will: 1) Enable accurate simultaneous EEG-fMRI recording in neonates (scientific advancement leading to high impact publications) 2) Enable extension of the study to various NHS sites, such as UCLH (scientific advancement leading to new collaborations) 3) Simplify EEG recording in neonates in experimental settings (scientific advancement leading to new experimental designs) 4) Simplify EEG recording in clinical settings (improvement to the quality of health care) 5) Inform the design of other MRI compatible EEG caps for other applications (e.g. brain-computer interface, cognitive neuroscience) 6) Enable EEG-fMRI recording with higher field strength, where the artefact may become an issue in adult as well 
 
Title Neonatal MRI compatible EEG cap 
Description This project aims to develop new electrodes to record electrical activity from the premature and newborn brain (EEG) in a magnetic resonance imaging (MRI) environment. We have currently tested new materials to make the electrodes in order to minimise MRI distortion and maximise patient comfort with the intention of producing a prototype to be used in pilot studies. 
Type Of Technology New/Improved Technique/Technology 
Year Produced 2016 
Impact This project may lead to the generation of new IP surrounding the MRI compatible EEG electrode which will: 1) Enable accurate simultaneous EEG-fMRI recording in neonates (scientific advancement leading to high impact publications) 2) Enable extension of the study to various NHS sites, such as UCLH (scientific advancement leading to new collaborations) 3) Simplify EEG recording in neonates in experimental settings (scientific advancement leading to new experimental designs) 4) Simplify EEG recording in clinical settings (improvement to the quality of health care) 5) Inform the design of other MRI compatible EEG caps for other applications (e.g. brain-computer interface, cognitive neuroscience) 6) Enable EEG-fMRI recording with higher field strength, where the artefact may become an issue in adult as well 
 
Title Somatosensory stimulator 
Description Development of a physiological somatosensory stimulator in collaboration with Imperial College London. We have developed a wearable glove to allow researchers to provide physiological tactile stimulation to neonates while monitoring the timing and force applied and time-lock the event to onging EEG recordings. 
Type Of Technology New/Improved Technique/Technology 
Year Produced 2018 
Impact This is an improvement over more standard stimulators which may not considered acceptable by the parents of the neonatal subjects. The glove can be hidden underneath a standard rubber glove and appears seemless. This will allow: 1) easier subject recruitment; 2) more complaiance in the neonatal ward; 3) potential stimulation of the face area which could not be done with standard stimulators. 
URL https://journals.plos.org/plosone/article/comments?id=10.1371/journal.pone.0207145
 
Description 700-words blog post for The Physiological Society by Kimberley Whitehead 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Kimberley Whitehead was invited to write a public engagement blog about doing neuroscience research with babies, versus using animal (fly and zebrafish) models, and the overlap between the neurobiology of different species. It was based on her public engagement event at the UCL Grant Museum of Zoology, held on 28th February 2018. This blog will be posted on the week of April 9th 2018.
Year(s) Of Engagement Activity 2018
URL https://physocblogs.wordpress.com/category/outreach-and-education/
 
Description Art Neuro (London) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact As part of the Art Neuro initiative Dr Madeleine Verriotis and I have teamed up with illustrator Martina Paukova to produce an illustration depicting the the atmosphere of the day-to-day working environment in our laboratory. The initiative intended to explore the world of neuroscience through the visual arts to provide an exciting, thought-provoking and unique visual experience.

The exhibition was very successful attracting the attention of audiences and press ( including The Guardian and Time Out)
Year(s) Of Engagement Activity 2014
 
Description Arts-science collaboration 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact My Research Associate - Kimberley Whitehead - has set up an Arts-Science collaboration with Matthew Beaumont - a Professor of English Literature at UCL. Matthew has a special interest in the way in which sleep is portrayed in literature. Meanwhile, Kim is investigating the way in which sleep in infants may intersect with the development of the somatosensory system. They were awarded a £3862 public engagement grant, and Kimberley supplemented this grant with a further £200 of funding from The Physiological Society. This money paid for three public engagement activities between January and February 2018: a full-day series of talks followed by a drinks reception, a lunch hour lecture (https://www.youtube.com/watch?v=CRbAdSkqpmw), and an evening event at the Grant Museum of Zoology.
Year(s) Of Engagement Activity 2017,2018
URL https://www.youtube.com/watch?v=CRbAdSkqpmw
 
Description Dr Fabrizi - Elected member of the Council of the Special Interest Group (SIG) on Pain in Childhood of the International Association for the Study of Pain 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dr Fabrizi has been elected member of the SIG on Pain in Childhood through an open international vote.

The objectives of the Pain in Childhood SIG are to: 1. promote education about pain in children; 2. share relevant information about children's pain control; 3. advance our ability to alleviate children's pain from an international and interdisciplinary perspective; 4. encourage research, particularly multicenter studies, and studies which focus on unique problems of pediatrics, including newborns.
The main event sponsored by the SIG is the biannual International Symposium on Pediatric Pain. The International Symposium on Pediatric Pain (ISPP) is the premier international, interdisciplinary conference on pain in infants, children, and adolescents.
Year(s) Of Engagement Activity 2020,2021
URL http://childpain.org/
 
Description Dr Fabrizi interviewed by Live Science 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Dr Fabrizi was interviewed by Live Science about Whitehead et al. (2019) Clinical Neurophysiology
Year(s) Of Engagement Activity 2019
URL https://www.livescience.com/why-we-hiccup.html
 
Description Dr Fabrizi interviewed by Research Professional News 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Dr Fabrizi was interviewed by Research Professional News about his experience in obtaining grant funding from the Medical Research Council
Year(s) Of Engagement Activity 2019
 
Description Dr Lorenzo Fabrizi interviewed by the BBC 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Dr Lorenzo Fabrizi was interviewed on the BBC World Service Health Check program by Claudia Hammond.
Year(s) Of Engagement Activity 2018
URL https://www.bbc.co.uk/programmes/p002vsyw/episodes/downloads
 
Description Dr Lorenzo Fabrizi spoke at Pint of Science 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Dr Lorenzo Fabrizi spoke at a Pint of Science event (public science event) about his work on using EEG to understand brain processing of sensory information
Year(s) Of Engagement Activity 2018
URL https://pintofscience.co.uk/event/the-brain-after-birth
 
Description Dr Whitehead poster presentation at the British Neuroscience Association Symposium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Poster presentations (2) at the British Neuroscience Association Meeting on work about somatosensory processing and movements in preterm human infants
Year(s) Of Engagement Activity 2021
 
Description Interview for GEO magazine 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Phone interview with Ines Possemeyer, science editor for GEO. This is a german monthly magazine similar to National Geographic (http://www.geo.de/magazine/geo-magazin) with a readership of 3,2 million. Ines was researching an extensive cover story on touch, ranging from ist role infant development and attachment to the recent development of haptic interfaces and got interested in my research.
Year(s) Of Engagement Activity 2017
 
Description Interview skills workshop organiser 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Dr Fabrizi organised a interivew skills workshop as part of his role in the UCL Neuroscience Career Network Committee to inform peers and students. This workshop aims at simulating interview scenarios to prepare fellowship candidates.
Year(s) Of Engagement Activity 2018
 
Description Kimberley Whitehead interviewed by Arizona radio station KJZZ 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Kimberley Whitehead interviewed by Arizona radio station KJZZ about the work in Whitehead et al. (2018) Sci Rep
Year(s) Of Engagement Activity 2018
URL https://science.kjzz.org/content/733100/baby-movements-womb-tied-neural-development
 
Description Kimberley Whitehead interviewed by The Naked Scientist 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Kimberley Whitehead was interviewed by The Naked Scientist about Whitehead et al. (2019) Clinical Neurophysiology
Year(s) Of Engagement Activity 2019
URL https://www.thenakedscientists.com/articles/interviews/hiccups-help-baby-brain-development
 
Description MRC Fellows' Induction Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact I was invited to talk about my experience as a MRC fellow to the 2015 and 2016 MRC Fellows' Induction Workshop. The aim of this workshop is to:
• Enable Fellows to reflect on what to expect during their fellowships and introduce common issues
• Facilitate networking with peers and MRC contacts
Year(s) Of Engagement Activity 2015,2016
 
Description Neuroscience-themed art exhibition with associated drinks reception with short talks for the general public October 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Kimberley Whitehead organised a two-week long exhibition during October 2018 of my commissioned art from Andrew Carnie themed around the neuroscience of sleep. This took place at the UCL Pathology Museum. On 16 October 2018 Kimberley Whitehead organised a drinks reception with short talks by myself (neuroscience), Andrew (art), and Dr Alan Bates (pathology). The drinks reception was fully subscribed and one of the biggest audiences the Pathology Museum has ever hosted. There were many questions, and many people stayed on for another glass of wine to talk to the speakers. Coincidentally, one of the mums of the babies Kim had recruited into our research attended the event, and remembered her baby's research fondly and still had photos on the phone of this.
Year(s) Of Engagement Activity 2018
URL https://www.ucl.ac.uk/culture/whats-on/representing-body
 
Description Organiser of a workshop abour grant writing 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Dr Fabrizi organised a workshop about grant writing as part of his role in the UCL Neuroscience Career Network Committee to inform peers and students. The feedback on the workshop was extremely positive
Year(s) Of Engagement Activity 2019
 
Description Patient engagement science-themed art workshop at the Teenage Cancer Unit University College London Hospital February 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Patients, carers and/or patient groups
Results and Impact Ten older children and adolescents with cancer attended a sleep science-themed arts workshop at the Teenage Cancer Unit where their treatment takes place. This was organised by Kimberley Whitehead. With their permission, Kimberley Whitehead took photos of their art and made anonymised notes on their experiences of sleep and sleeplessness and what they find most interesting about the topic.
Year(s) Of Engagement Activity 2018
 
Description Presentation at a Neonatal Nurses Training Day, University College London Hospitals 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact On 23 July 2018 I presented our research to a group of nurses who facilitate this research by allowing us to work on their wards etc. The nurses showed interest in the research and asked to continue to be kept up to date. I was asked to add a few of our key academic papers to their shared drive on the hospital computer network.
Year(s) Of Engagement Activity 2018
 
Description Press release for Arichi et al. (2017) eLife 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Prepared a media press release in collaboration with the UCL Press Office.
Year(s) Of Engagement Activity 2017
URL http://www.ucl.ac.uk/news/news-articles/0917/120917-Explaining-bursts-of-activity-in-brains-of-prete...
 
Description Press release for Donadio et al. (2018) Plos One 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Prepared a media press release in collaboration with the UCL Press Office.
Year(s) Of Engagement Activity 2018
URL https://www.ucl.ac.uk/news/2018/nov/newborn-babies-brain-responses-being-touched-face-measured-first...
 
Description Press release for Whitehead et al. (2019) Clinical Neurophysiology 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Prepared a media press release in collaboration with the UCL Press Office, which was picked up by Telegraph, Times, Mail Online, People, CNN (and in Spanish), Sky News (and in Italian), BBC World Service's 'Health Check' (from 24 mins 15 secs), Irish News, Huffington Post, Yahoo!, ABC (Spain), RIA Novosti (Russia), Indian Express, BILD (Germany), LCI (France), Het Nieuwsblad (Belgium), NHS 'Behind the Headlines', CBS Boston, i News (print only), Metro (print only).
Year(s) Of Engagement Activity 2019
URL https://www.ucl.ac.uk/news/2019/nov/newborn-baby-hiccups-could-be-key-brain-development
 
Description Press release for Whitehead st el. (2018) Sci Rep 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Prepared a media press release in collaboration with the UCL Press Office.
Year(s) Of Engagement Activity 2018
URL https://www.ucl.ac.uk/news/2018/nov/babies-kicking-womb-are-creating-map-their-bodies
 
Description Science media article about Arichi et al. (2017) eLife in The Conversation 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Wrote an article for "The Conversation" which is a public science media outlet. The article was picked up with "The Indipendent" and "The Financial Times". As a result the article Arichi et al. (2017) eLife has an altmetric score of 124 (top 5% of all research output ever tracked by Altmetric, >8 million)
Year(s) Of Engagement Activity 2017
URL https://theconversation.com/how-a-babys-brain-prepares-for-the-outside-world-72708
 
Description Scientists Meet the Media Party 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Event held at the Science Museum to bring scientists and media professional together. As a result I am preparing a piece with a Jo Adetunji, writer for The Conversation. The Conversation is an independent source of information that aims to connect the wider public with the latest research, analysis and opinion from the university and research sector. Read more at http://theconversation.com
Year(s) Of Engagement Activity 2017
 
Description UCLH Research Open Day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Patients, carers and/or patient groups
Results and Impact We have organised an educational stand including display and engaging activities (such as a science based quiz) to showcase our research to patients, carers, schools and the general public.
Year(s) Of Engagement Activity 2015
 
Description Video interview for Pharmastar 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Video interview about the work presented at the SIMPAR Rome 2015 on the development of pain perception in premature neonates for an Italian on-line newspaper for clinical practitioner and health carers (Pharmastar)
Year(s) Of Engagement Activity 2015
URL http://www.pharmastar.it/index.html?pgnav=12&id=2308
 
Description Workshop about Fellowship Interview 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact I talked at a local workshop about Fellowship interview preparation reporting my personal experience. Participants reported that my honest report helped them in demystifing the process and were less afraid of attempting application.
Year(s) Of Engagement Activity 2017
URL http://www.ucl.ac.uk/research/domains/neuroscience/neuroscience-careers-network/events/past-events-a...
 
Description Workshop organiser about media engagement 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact I organised a workshop about engaging with the media as part of my role in the UCL Neuroscience Career Network Committee to inform peers and students. One of the participants reported writing an article for The Conversation as a result of the workshop.
Year(s) Of Engagement Activity 2018
URL http://www.ucl.ac.uk/research/domains/neuroscience/neuroscience-careers-network/events/past-events-a...
 
Description Workshop organiser about teaching opportunities for PhD students and postdocs 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Dr Fabrizi organised a workshop about teaching opportunities for PhD students and postodocs as part of his role in the UCL Neuroscience Career Network Committee to inform peers and students.
Year(s) Of Engagement Activity 2018
 
Description in2scienceuk 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Kimberley Whitehead (research assistant on this grant) organised one week summer placement for high-school students from disadvantaged backgrounds. The next is scheduled for summer 2019. I conducted half a day mentoring for these placements.
Year(s) Of Engagement Activity 2015,2016,2017,2019
 
Description methods for dummies 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact My research assistant gave two talks about EEG and fMRI as part of this series of lectures.
Methods for Dummies (MfD) is a course taught by its participants, and aims to give a basic introduction to human brain imaging analysis methods, focusing on fMRI and M/EEG.
Impact: networking with other peers, consolidating knowledge of analysis techniques
Year(s) Of Engagement Activity 2016
URL http://www.fil.ion.ucl.ac.uk/mfd/