Newton001 - A collaboration Brazil UK on e health preparing a virtual cohort of 80 million Brazilians
Lead Research Organisation:
London School of Hygiene & Tropical Medicine
Department Name: Epidemiology and Population Health
Abstract
An MoU was signed between LSHTM, Universidade Federal da Bahia-ISC and FIOCRUZ in 2014; a delegation from UFBA and FIOCRUZ visited the LSHTM in 2014. Mauricio Barreto (the Brazilian PI) has a LSHTM PhD, and 3 other LSHTM PhDs hold academic positions at ISC; 3 students from ISC are split or full PhD current students at LSHTM. Mauricio was LSHTM "Heath Clarke Lecturer" in 2013 and now hold an Honorary Professorship there. Laura Rodrigues, the UK co-PI holds a Science Without Borders Visiting Professorship ("PVE") at ISC. Professors Laura and Mauricio had two major joint research projects: "BCG REVAC, a large trial of efficacy of BCG revaccination, co funded by DfID and the Ministry of Health/Tuberculosis Control Programme in Brazil and "SCAALA", a Wellcome Trust funded "Centre of Excellence in Latin America" dedicated to Social Change, Allergy and Asthma in Latin America and now co-funded by the Brazilian National Research Council-CNPq and FAPESB.. This collaboration resulted so far in 89 papers published in peer review journals; Several PhDs (8) and Masters (7) theses were developed as part of these projects.
Liam Smeeth is a deputy director of the London Farr Institute, has visited ISC to present on the Farr Institute and use of routine electronic data and is a scientific advisor for the development of the 80 million Brazilians Virtual cohort.
Liam Smeeth is a deputy director of the London Farr Institute, has visited ISC to present on the Farr Institute and use of routine electronic data and is a scientific advisor for the development of the 80 million Brazilians Virtual cohort.
Technical Summary
An MoU was signed between LSHTM, Universidade Federal da Bahia-ISC and FIOCRUZ in 2014; a delegation from UFBA and FIOCRUZ visited the LSHTM in 2014. Mauricio Barreto (the Brazilian PI) has a LSHTM PhD, and 3 other LSHTM PhDs hold academic positions at ISC; 3 students from ISC are split or full PhD current students at LSHTM. Mauricio was LSHTM "Heath Clarke Lecturer" in 2013 and now hold an Honorary Professorship there. Laura Rodrigues, the UK co-PI holds a Science Without Borders Visiting Professorship ("PVE") at ISC. Professors Laura and Mauricio had two major joint research projects: "BCG REVAC, a large trial of efficacy of BCG revaccination, co funded by DfID and the Ministry of Health/Tuberculosis Control Programme in Brazil and "SCAALA", a Wellcome Trust funded "Centre of Excellence in Latin America" dedicated to Social Change, Allergy and Asthma in Latin America and now co-funded by the Brazilian National Research Council-CNPq and FAPESB.. This collaboration resulted so far in 89 papers published in peer review journals; Several PhDs (8) and Masters (7) theses were developed as part of these projects.
Liam Smeeth is a deputy director of the London Farr Institute, has visited ISC to present on the Farr Institute and use of routine electronic data and is a scientific advisor for the development of the 80 million Brazilians Virtual cohort.
Liam Smeeth is a deputy director of the London Farr Institute, has visited ISC to present on the Farr Institute and use of routine electronic data and is a scientific advisor for the development of the 80 million Brazilians Virtual cohort.
Planned Impact
The Farr Institute of Health Informatics Research comprises four nodes distributed across the UK and led from the University College London (Farr Institute @ London), University of Manchester (Farr Institute @ HeRC N8), Swansea University (Farr Institute @ CIPHER), and the University of Dundee (Farr Institute @ Scotland). With a £17.5m-research award from a 10-funder consortium (including the MRC, ESRC and EPSRC), plus additional £20m-capital funds from the MRC, the Farr Institute aims to deliver high-quality, cutting-edge research linking electronic health data with other forms of research and routinely collected data. Capacity Building activities across Farr will train a new cadre of health informaticians and related methodologists, providing the academic and professional underpinning of world-leading e-Health innovation from the UK. International collaboration is central to the mission of the Farr Institute, but to date has been relatively limited. The UK-Brazil collaboration proposed here will bring together UK expertise and experience in e-health with the unique data resources and public health research excellence offered by Brazil.
Brazil has a national health system (SUS) based on its constitutional principle of health as citizen right and a State duty. As part of the effort to improve the health the health information systems has improved and now there is several reliable national databases covering different aspects (i.e., use of services, morbidity and mortality). It is clearly understood that the possibility to link these different databases will create a unique opportunity to improve research and management of the health system. The existing legal framework and ethical regulations are clear supportive of such uses given there is capability to protect confidentiality and the results are used for the public good. To transfer to Brazil experience already accumulated in the UK will speed this process.
Brazil has a national health system (SUS) based on its constitutional principle of health as citizen right and a State duty. As part of the effort to improve the health the health information systems has improved and now there is several reliable national databases covering different aspects (i.e., use of services, morbidity and mortality). It is clearly understood that the possibility to link these different databases will create a unique opportunity to improve research and management of the health system. The existing legal framework and ethical regulations are clear supportive of such uses given there is capability to protect confidentiality and the results are used for the public good. To transfer to Brazil experience already accumulated in the UK will speed this process.
Publications
Grieve R
(2016)
Cancer Drugs Fund requires further reform.
in BMJ (Clinical research ed.)
Van Staa TP
(2016)
Big health data: the need to earn public trust.
in BMJ (Clinical research ed.)
| Description | How the scientific community should go about getting the best research out of big data |
| Geographic Reach | South America |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Presentation and discussion with governmental figures led to policies to improve data access |
| Description | Henry Wellcome Fellowship |
| Amount | £300,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2019 |
| End | 05/2023 |
| Description | The 100 million cohort in Bazil |
| Amount | £1,500,000 (GBP) |
| Funding ID | 202912/Z/16/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 10/2021 |
| Title | 100 million cohort |
| Description | We have successfully linked and curated health and social records for more than 100 million people in Brazil. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | We have several papers in development or submitted. We have had regular discussions with the Ministry of Health in Brazil and our work is directly informing their efforts on a wide range of health issues and on social programmes to improve health. |
| URL | https://cidacs.bahia.fiocruz.br/en/ |
| Description | Brazil |
| Organisation | Federal University of Bahia |
| Country | Brazil |
| Sector | Academic/University |
| PI Contribution | We have undertaken joint collaborative visits and organised joint workshops. We have developed a major funding application. |
| Collaborator Contribution | As above: all are shared activities. |
| Impact | A full application to the Wellcome Trust for a Biomedical Resources award. |
| Start Year | 2015 |
| Description | Better e-health research - Pan-London Public Health Trainees annual meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave presentation |
| Year(s) Of Engagement Activity | 2016 |
| Description | Better scientific reporting in e-health |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented and discussed the RECORD statement Increase in requests for further information |
| Year(s) Of Engagement Activity | 2015 |
| Description | Bring geneomics and electronic health records together |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Present our own work in diabetic retinopathy Plans made for future related activity |
| Year(s) Of Engagement Activity | 2015 |
| Description | Cambridge Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | 'Hands off my Health Records' panel on sharing health data at the Cambridge Science Festival. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Chair - Epidemiology and Population Health? Researcher meeting on Genetics, genomics, epidemiology and disease processes at the Wellcome Trust |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chaired session |
| Year(s) Of Engagement Activity | 2016 |
| Description | Clinical evidence, the need for novel approaches. International Congress of Pharmacoepidemiology workshop leader and presentation in Dublin, Ireland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave presentation |
| Year(s) Of Engagement Activity | 2016 |
| Description | E-health and randomised trials: the way forward |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation of our own work International Conference on Pharmacoepidemiology & Therapeutic Risk Management Boston, USA |
| Year(s) Of Engagement Activity | 2016 |
| Description | Health data: better care or privacy nightmare - British Library Talk Science event in London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Gave presentation |
| Year(s) Of Engagement Activity | 2016 |
| Description | Making optimal use of electronic health records |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | Gave presentation |
| Year(s) Of Engagement Activity | 2016 |
| Description | Optimal use of primary care health records. International Congress of Pharmacoepidemiology workshop leader and presentation in Dublin, Ireland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave presentation |
| Year(s) Of Engagement Activity | 2016 |
| Description | Your health data: really private and really important? Science Museum Lates series, big data in London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Gave presentation |
| Year(s) Of Engagement Activity | 2007,2016 |