MRC Centre for Medical Mycology

Lead Research Organisation: University of Aberdeen
Department Name: Sch of Medicine, Medical Sci & Nutrition

Abstract

The major contribution of fungi to the global burden of disease is not widely appreciated, despite the fact that fungi infect billions of people annually. While most infections are non-life threatening superficial infections, such as athlete's foot, millions of people contract invasive fungal diseases resulting in global mortality figures that rival those of tuberculosis or malaria. Despite their huge burden and high rates of death, fungal infections remain understudied compared with other infectious diseases and there is a pressing need for more research in this field. Experts in the field, including Aberdeen scientists, have identified three priorities that require urgent attention: (i) to improve our ability to detect fungal infections, (ii) to generate better antifungal drugs, and (iii) to enhance the understanding of fungal immunity and its exploitation to fight these diseases. The limited progress in tackling these challenges is due, in large part, to a lack of basic and clinical scientists working in this field in the UK and worldwide.

The UK has a small but highly active community of scientists working on fungal diseases (medical mycologists), with the largest group based at The University of Aberdeen (the Aberdeen Fungal Group, AFG). The AFG, which consists of 11 independent research teams, totalling around eighty individuals, is internationally recognised as a leading group in this field. We aim to achieve maximal synergistic potential within the diverse expertise of the AFG by establishing a world-leading MRC Centre of excellence for research and training in Medical Mycology (MCMM). The MCMM will focus on performing cutting-edge interdisciplinary research and on training the next generation of scientists to increase research capacity in this neglected field in the UK.

Establishing the MCMM will facilitate full integration of the complementary areas of expertise into six exciting research themes that address the key priorities of this field. Moreover, creation of the MCMM will lead to the recruitment of two academics whose expertise will add significant complementary value to the current group, and enable expansion of our research capacity into important new areas. One post will be in Bioinformatics, which will study and help process our massive biological datasets. This post will empower new technologies that will allow us to gain important insights into the mechanisms of fungal disease. The second post will be in immunology which, in addition to delivering cutting-edge science, will help promote the translation of our scientific discoveries into new diagnostic, preventative and therapeutic applications. The MCMM will also be used as a platform to raise awareness and influence policy regarding the management of fungal diseases within the broader academic community and the general public.

A major objective of the MCMM is to increase capacity in medical mycology in the UK by delivering a cohort of 21 basic and clinical researchers through a range of world leading training programmes. This will include a bespoke four-year MRes-PhD programme for 13 students that will provide a broad interdisciplinary training that is not available anywhere else; 3 Early Career Fellowships to promote an early independent research career in medical mycology for outstanding individuals; 5 Fellowships for excellent clinical trainees to provide one year of focussed academic training and research and to establish a foundation for subsequent PhD fellowship applications; and 10 eight-week summer scholarships for fourth-year medical students to stimulate their interest in medical mycology, and to promote links between the MCMM and other centres in this field. The MCMM Fellows, PhD students and clinical trainees will underpin the integration of the AFG, through appointment to jointly-supervised projects within our new research themes, and will significantly advance our understanding of fungal disease.

Technical Summary

We will create an MRC Centre which is recognised internationally as a leading centre of excellence for research and training in Medical Mycology (the MCMM). Creation of the MCMM will enable us to establish an optimal configuration that will exploit our collective strength and will maximise our potential for fundamental and translational science, as well as for providing world-leading training in medical mycology. New posts in bioinformatics and in experimental immunology will add scope, depth and translatability to our existing research strengths. Six innovative and cross-disciplinary research themes are proposed:

1. Fungal cell surface dynamics and its impact on antimicrobial chemotherapy and host immunity;

2. Fungal components as antifungal drug targets, diagnostics, vaccine antigens and adjuvants;

3. Fungal growth, adaptation and morphogenesis in the context of infection;

4. Temporal host-fungal interactions and key mediators that influence disease establishment and progression at molecular, cellular and organismal levels;

5. Exploiting emerging technologies to generate global perspectives that broaden our mechanistic understanding of host-fungal interactions;

6. Unravelling patient susceptibility to enable directed diagnosis, treatment and prevention of fungal disease.

MCMM Early Career Fellows, PhD students and clinical trainees will enable these research themes and foster interconnectivity and interdisciplinarity within and beyond the MCMM. The training of these Fellows and students will address the urgent requirement for increased capacity in basic and clinical research in this neglected field in the UK. Creation of the MMCM will also accelerate translation of our science and promote a vibrant public outreach programme, maximising the impact of the excellent mycology research that occurs in Aberdeen.

Planned Impact

We propose to establish an MRC Centre in Medical Mycology (MCMM), an area of infectious disease that has enormous impact on morbidity and mortality but whose influence on human health is not widely appreciated. Creation of a world-leading centre of excellence for research and training in medical mycology will provide benefit to academia, industry, clinicians and the general public.

Benefits to academia: The training programmes within the MCMM will produce a cohort of basic scientists and clinicians with expertise in medical mycology. This cohort will contribute to building research capacity in this neglected field in the UK, adding vitality to the sector. The training and mentoring of a new cohort of Early Career Fellows will similarly contribute to capacity building in this field. Research projects addressing our new themes will lead to new interdisciplinary collaborations and advance our understanding of fungal disease. The results generated will be of interest to a wide range of specialities including, for example, immunologists and systems biologists as well as clinical academics in several specialities including, for example, infectious disease and dermatology.

Benefits to industry: Research in the MCMM will address the most pressing questions in medical mycology and is very likely to generate exploitable data, tools and resources that will advantage industry. For example, our ongoing and planned research activities will contribute directly to the development of new diagnostic platforms and drug discovery screens. Exploitation of these discoveries will be achieved through our extensive and longstanding links with other universities, SMEs and pharmaceutical companies, and the support of key translational infrastructure that is available at the University of Aberdeen. These activities will be enhanced by our institution's MRC Confidence in Concept and Wellcome Trust ISSF awards.

Benefits to clinicians: In addition to increasing capacity in clinical medical mycology through our training programme, MCMM research has the potential to improve management strategies and patient outcome in the future. In addition to the exploitable discoveries described above, for example, the new insights into antifungal immunity that we will generate may help explain susceptibility to infection and lead to the development of novel immunotherapeutic approaches. As described in the Case for Support, we have already made impacts in such areas.

Benefits to patients and the general public: The creation of the MCMM will help focus national and international attention on this important area of infectious disease. Our research will be of interest to the general public because many individuals suffer from fungal infections, as detailed in our Case for Support. We plan to disseminate information about fungal infections in the scientific and popular press, on the Internet and social media, through live events and our other outreach activities. The MCMM will host open days, continue school outreach activities, and host work experience and placement programmes for undergraduate students. MCMM members will continue to provide guest lectures on medical mycology to basic science and clinical undergraduates and postgraduates at universities throughout the UK, to raise awareness of this field. Moreover, MCMM members will continue to be involved in national patient organizations and to present our research to patients and their relatives. All MCMM staff will be involved in public outreach activities. In the longer term, MCMM research will contribute to improved treatment and outcome, resulting in enhanced quality of life and reduced impact on health care budgets.

Benefits to our Students and Fellows: In addition to world-leading training in medical mycology, the MCMM will actively promote the career development of trainees through close mentoring, training in transferable skills, and the development of strong support networks.

Publications

10 25 50
 
Description AFGrica unit at the University of Cape Town
Geographic Reach Africa 
Policy Influence Type Influenced training of practitioners or researchers
Impact A special unit in medical mycology (the University of Aberdeen AFGrica Unit) that is based in the Institute of Infectious Diseases and Molecular Medicine at the University of Cape Town, and jointly managed with the UoA. The primary objectives of this unit is to create a base of operations for the University of Aberdeen in Africa, to establish research programmes focused on priority areas in fungal diseases relevant to Africa, and to disseminate expertise and training in medical mycology throughout the continent. No such facility targeting fungal diseases currently exists anywhere in the world. Since the launch of the unit in 2017, the unit in collaboration with the MRC CMM and other partner shave organised several workshops in Cape town; (1) 8th August 2017: Medical Mycology for MSc, PhDs and Postdocs covering subjects such as basic medical mycology, emerging fungal pathogens and the immune response and the clinical relevance of fungal infections. The sessions were run by Professors, Alistair Brow, Gordon Brown, Neil Gow and Adilia Warris. (2) 10 - 14th December 2018: Lecture and Practical Course in Medical Mycology for Scientists and Clinicians in collaboration with the Institut Pasteur Paris and AMBITION-cm. The event focused on the key fungal pathogens in Africa and covered the microbiological, immunological and clinical aspects of these fungal pathogens and infections.  
 
Description British Paediatric Allergy Immunity and Infection Group (BPAIIG) - Medical Mycology: Bench to Beside
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact This 2-day CPD residential workshop for medical professionals working in paediatrics with specialty in allergy, immunity and infection was organised by Professor Adilia Warris, Deputy Director for Clinical Training in MRC CMM and held on 21-22nd September 2017. The workshop covered topics such as an introduction to fungal pathogen given by Dr Liz Johnston, Director of Mycology Reference Laboratory, Public Health England Bristol, immunology, clinical spectrum for fungal pathogen diseases - Aspergillus and Candida, Laboratory based teaching, Clinical Case studies with discussions, antifungal therapies for paediatrics, antifungal drug resistance, and antifungal stewardship. A workshop involved presentations from external clinician scientists working with patients and several of the MRC CMM principal investigators. Official feedback from the workshop was extremely positive and clinicians working in different hospital valued the opportunity to have open discussion with colleagues.
 
Guideline Title Guidelines for the Management of Invasive Fungal Infections
Description Dutch Working Party of Antibiotic Policy (SWAB) - contribution by Professor Adilia Warris
Geographic Reach Europe 
Policy Influence Type Citation in clinical guidelines
Impact Professor Adilia Warris was a member of the working group under the Dutch Working Party of Antibiotic Policy (SWAB) during the year 2017 which has resulted in the 'Guidelines for the Management of Invasive Fungal Infections' and is published in full on the SWAB website. This national clinical management guideline is dedicated to the diagnosis and therapy of invasive fungal disease across all patient populations in the Netherland.
URL http://www.swab.nl/swab/cms3.nsf/uploads/3AA7A56CE879587BC12581F80061297F
 
Description EMBO Workshop on AIDS-related Mycoses
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact The EMBO Workshops on AIDS-related Mycoses is organised by the Institute of Infectious Disease and Molecular Medicine (IDM) and the AFGrica unit at the University of Cape Town. Professor Gordon Brown, Director of MRC CMM is the founder and chair of the EMBO Workshop. It is open to scientists and clinicians interested in the interaction of fungal pathogens with HIV-infected host. The 3rd workshop will be run from 10- 12th July 2019.
URL http://www.aidsmycoses2019.co.za/
 
Description ESCMID-ECMM Guideline for the Diagnosis and Management of Aspergillus Disease - contribution by Professor Adilia Warris
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical reviews
Impact Professor Adilia Warris, deputy director of clinical training in MRC CMM/AFG, was a member on the ESCMID-ECMM Guideline for the Diagnosis and Management of Aspergillus Disease executive working group. The development of this guideline took place between 2015 and 2017, and has resulted in a peer-review publication in Clinical Microbiology and Infection 2018 (Ullman et al, Diagnosis and Management of Aspergillus Diseases: Executive Summary of the 2017 ESCMID-ECMM-ERS Guideline. CMI 2018 in press). This international clinical management guideline is specifically dedicated to the diagnosis and therapy of invasive aspergillosis across all patient populations susceptible to develop invasive Aspergillus disease. The guidelines fall under the authority of the European Society of Clinical Microbiology and Infectious Diseases, the European Confederation of Clinical Mycology, and the European Respiratory Society. In addition, Professor Warris acts as the coordinator of the paediatric subgroup, which will publish in addition to the executive summary a full paper with explanations of the recommendations made specifically for the paediatric population. Submission expected 2018.
 
Guideline Title Guidelines for the diagnosis, prevention and treatment of invasive fungal diseases in paediatric patients undergoing allogeneic haematopoietic stem cell transplantation
Description UK Paediatric Bone Marrow Transplant Working Group '
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
Impact Professor Adilia Warris, deputy director of clinical training in the MRC CMM/AFG was a member of the UK Paediatric BMT Working Group 'Guidelines for the diagnosis, prevention and treatment of invasive fungal diseases in paediatric patients undergoing allogeneic haematopoietic stem cell transplantation' in 2016 and 2017, which has resulted in a national practice guideline for all the paediatric BMT centres in the UK.
 
Description CGD Society UK Research Grant to Professors Adilia Warris and Gordon Brown
Amount £14,141 (GBP)
Organisation CGD Society UK 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2017 
End 01/2018
 
Description Development Trust University of Aberdeen: "AFGrica unit; Promoting Medical Mycology in Africa" (£600.000
Amount £600,000 (GBP)
Organisation University of Aberdeen 
Sector Academic/University
Country United Kingdom
Start 04/2016 
End 03/2021
 
Description Enterprise Fellowship
Amount £59,503 (GBP)
Organisation Royal Society of Edinburgh (RSE) 
Sector Learned Society
Country United Kingdom
Start 04/2017 
End 04/2018
 
Description High Growth Spinout Programme - to Dr Fiona Rudkin
Amount £400,000 (GBP)
Organisation Scottish Enterprise 
Sector Public
Country United Kingdom
Start 08/2018 
End 06/2020
 
Description Impact Knowledge Exchange and Commercialisation (IKEC) - to Dr Fiona Rudkin
Amount £8,000 (GBP)
Organisation University of Aberdeen 
Sector Academic/University
Country United Kingdom
Start 11/2017 
End 07/2018
 
Description Institutional Strategic Support Fund (ISSF) - Seed Corn Award to Dr Fiona Rudkin
Amount £18,949 (GGP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2017 
End 10/2018
 
Description Institutional Strategic Support Fund (ISSF) - specific call for International Partnerships - AFGrica unit to Prof Gordon Brown
Amount £5,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2017 
End 10/2018
 
Description Investigator Led Study
Amount £77,000 (GBP)
Organisation Gilead Sciences, Inc. 
Sector Private
Country United States
Start 05/2019 
End 04/2020
 
Description MRC Festival of Medical Research 2017
Amount £1,500 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 02/2017 
End 07/2017
 
Description MRC Festival of Medical Research Establishment Award
Amount £1,500 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2018 
End 01/2019
 
Description Marie Sklodowska-Curie Innovative Training Network (Professors Carol Munro and Alistair Brown)
Amount £409,000 (GBP)
Organisation European Union 
Sector Public
Country European Union (EU)
Start 06/2018 
End 05/2023
 
Description Public Engagement Funds to Dr Donna MacCallum
Amount £2,500 (GBP)
Organisation Microbiology Society 
Sector Learned Society
Country Unknown
Start 08/2016 
End 06/2017
 
Description Public Engagement Funds to Dr Donna MacCallum
Amount £930 (GBP)
Organisation National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) 
Sector Private
Country United Kingdom
Start 08/2016 
End 10/2016
 
Description Public Engagement Funds to Professor Neil Gow
Amount £2,500 (GBP)
Organisation Microbiology Society 
Sector Learned Society
Country Unknown
Start 08/2016 
End 12/2017
 
Description Research grant to Professor Adilia Warris
Amount £10,000 (GBP)
Organisation University of Aberdeen 
Department Development Trust
Sector Charity/Non Profit
Country United Kingdom
Start 12/2016 
End 11/2017
 
Description Seed Award (Dr Rhys Farrer)
Amount £97,523 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2019 
End 09/2020
 
Description Senior Research Fellow (Dr Duncan Wilson)
Amount £1,712,380 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2019 
End 04/2024
 
Description Senior Research Fellow - Dr Alexandra Brand
Amount £1,258,447 (GBP)
Funding ID 206412/Z/17/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2018 
End 09/2022
 
Description Senior Research Fellowship (Professor Carol Munro)
Amount £56,000 (GBP)
Organisation The Leverhulme Trust 
Sector Academic/University
Country United Kingdom
Start 02/2019 
End 01/2020
 
Description Wellcome ISSF International Partnerships - ODA Awards: Prof Adilia Warris - "Epidemiology of fungal infections in children with HIV/AIDS and tuberculosis in South Africa."
Amount £7,600 (GBP)
Organisation University of Aberdeen 
Sector Academic/University
Country United Kingdom
Start 06/2017 
End 05/2019
 
Description 8-week Summer Scholarships 
Organisation Imperial College London
Department National Heart & Lung Institute (NHLI)
Country United Kingdom 
Sector Academic/University 
PI Contribution The MRC CMM offers medical students studying for a BSc programme the opportunity to spend 8-weeks doing a research project at a leading medical mycology research lab anywhere in the world. The students have to apply for the scholarship and undergo an interview process. Running parallel to this process, the principal investigators (PIs) in the MRC CMM along with colleague PI from another lab (in UK, Europe or international) submit joint projects to the MRC CMM for peer review and selection. Successful medical students can select a research project that they would like to do during the 8-week summer visit. Students are required to record a short You Tube film outlining their research project and experiences of working in an internationally renowned lab. In 2018, two medical students , Dylan McClurg (2nd Year) and Yagna Bhattacharya (4th year) were awarded the 8-week summer research scholarships. Details of their project are given below: Dylan McClurg: Professor Arturo Casadevall (Johns Hopkins Bloomberg), host supervisor on project "Disarming the macrophage: arginases and Cryptococcus", Professor Neil Gow (MRC CMM) was the co-supervisor. Yagna Bhattacharya: Dr Darius Armstrong James (Imperial College London) host supervisor on project "Characterise the associated changes in cell wall composition that occur in isolates from chronically infected patients and how these correlate with fungal genotype and disease severity"; Professor Gordon Brown (MRC CMM) was the co-supervisor.
Collaborator Contribution Dylan McClurg: Professor Arturo Casadevall (Johns Hopkins Bloomberg), host supervisor on project "Disarming the macrophage: arginases and Cryptococcus", Professor Neil Gow (MRC CMM) was the co-supervisor. Yagna Bhattacharya: Dr Darius Armstrong James (Imperial College London) host supervisor on project "Characterise the associated changes in cell wall composition that occur in isolates from chronically infected patients and how these correlate with fungal genotype and disease severity"; Professor Gordon Brown (MRC CMM) was the co-supervisor.
Impact The results produced by Dylan McClurg during his research visit have proved interesting and if they can be reproduced in repeat experiments will lead to a publication. Dylan has also been inspired to pursue a research Masters as part of his intercalated year. The feedback from each host laboratory has been extremely positive and both host supervisors indicated that the two medical students should be encouraged to pursue a career in academic clinical medicine in medical mycology.
Start Year 2018
 
Description 8-week Summer Scholarships 
Organisation Johns Hopkins University
Department Johns Hopkins Bloomberg School of Public Health
Country United States 
Sector Academic/University 
PI Contribution The MRC CMM offers medical students studying for a BSc programme the opportunity to spend 8-weeks doing a research project at a leading medical mycology research lab anywhere in the world. The students have to apply for the scholarship and undergo an interview process. Running parallel to this process, the principal investigators (PIs) in the MRC CMM along with colleague PI from another lab (in UK, Europe or international) submit joint projects to the MRC CMM for peer review and selection. Successful medical students can select a research project that they would like to do during the 8-week summer visit. Students are required to record a short You Tube film outlining their research project and experiences of working in an internationally renowned lab. In 2018, two medical students , Dylan McClurg (2nd Year) and Yagna Bhattacharya (4th year) were awarded the 8-week summer research scholarships. Details of their project are given below: Dylan McClurg: Professor Arturo Casadevall (Johns Hopkins Bloomberg), host supervisor on project "Disarming the macrophage: arginases and Cryptococcus", Professor Neil Gow (MRC CMM) was the co-supervisor. Yagna Bhattacharya: Dr Darius Armstrong James (Imperial College London) host supervisor on project "Characterise the associated changes in cell wall composition that occur in isolates from chronically infected patients and how these correlate with fungal genotype and disease severity"; Professor Gordon Brown (MRC CMM) was the co-supervisor.
Collaborator Contribution Dylan McClurg: Professor Arturo Casadevall (Johns Hopkins Bloomberg), host supervisor on project "Disarming the macrophage: arginases and Cryptococcus", Professor Neil Gow (MRC CMM) was the co-supervisor. Yagna Bhattacharya: Dr Darius Armstrong James (Imperial College London) host supervisor on project "Characterise the associated changes in cell wall composition that occur in isolates from chronically infected patients and how these correlate with fungal genotype and disease severity"; Professor Gordon Brown (MRC CMM) was the co-supervisor.
Impact The results produced by Dylan McClurg during his research visit have proved interesting and if they can be reproduced in repeat experiments will lead to a publication. Dylan has also been inspired to pursue a research Masters as part of his intercalated year. The feedback from each host laboratory has been extremely positive and both host supervisors indicated that the two medical students should be encouraged to pursue a career in academic clinical medicine in medical mycology.
Start Year 2018
 
Description 8-week Summer scholarship partner universities 
Organisation Duke University
Country United States 
Sector Academic/University 
PI Contribution The MRC CMM offers medical students studying for a BSc programme the opportunity to spend 8-weeks doing a research project at a leading medical mycology research lab anywhere in the world. The students have to apply for the scholarship and undergo an interview process. Running parallel to this process, the principal investigators (PIs) in the MRC CMM along with colleague PI from another lab (in UK, Europe or international) submit joint projects to the MRC CMM for peer review and selection. Successful medical students can select a research project that they would like to do during the 8-week summer visit. Students are required to record a short You Tube film outlining their research project and experiences of working in an internationally renowned lab.
Collaborator Contribution The non-MRC CMM PI agrees to host the student and supervise the research project during the 8-week visit. . In 2017, Professor William Steinbach, Duke University and Professor Bernhard Hube, Leibniz Institute each hosted two Aberdeen medical students, Calum Barnetson and Anastasyia Kret respectively.
Impact In 2017, two University of Aberdeen medical students successfully completed their 8-week research projects. The students recorded their experiences which can be viewed on the URL above. Anastasyia Kret talks about her experiences in Jena working in Professor Bernhard Hube's lab on the role of the Candidalysin-coding gene ECE1 during interaction of C. albicans with bacteria and the host. Calum Barnetson tells us about his time working in Professor William Steinbach's lab at Duke University working on the calcineurin pathway and developing a novel fungal-specific antifungal through understanding the exact mechanisms of invasive pathogenesis and weak areas to target. The feedback from the host laboratories was extremely positive. Results generated by Calum will be included in a publications. Professor Hube indicated that eh would be happy to host an 8-week scholar in future rounds.
Start Year 2017
 
Description 8-week Summer scholarship partner universities 
Organisation Leibniz Association
Department Leibniz Institute for Natural Product Research and Infection Biology
Country Germany 
Sector Public 
PI Contribution The MRC CMM offers medical students studying for a BSc programme the opportunity to spend 8-weeks doing a research project at a leading medical mycology research lab anywhere in the world. The students have to apply for the scholarship and undergo an interview process. Running parallel to this process, the principal investigators (PIs) in the MRC CMM along with colleague PI from another lab (in UK, Europe or international) submit joint projects to the MRC CMM for peer review and selection. Successful medical students can select a research project that they would like to do during the 8-week summer visit. Students are required to record a short You Tube film outlining their research project and experiences of working in an internationally renowned lab.
Collaborator Contribution The non-MRC CMM PI agrees to host the student and supervise the research project during the 8-week visit. . In 2017, Professor William Steinbach, Duke University and Professor Bernhard Hube, Leibniz Institute each hosted two Aberdeen medical students, Calum Barnetson and Anastasyia Kret respectively.
Impact In 2017, two University of Aberdeen medical students successfully completed their 8-week research projects. The students recorded their experiences which can be viewed on the URL above. Anastasyia Kret talks about her experiences in Jena working in Professor Bernhard Hube's lab on the role of the Candidalysin-coding gene ECE1 during interaction of C. albicans with bacteria and the host. Calum Barnetson tells us about his time working in Professor William Steinbach's lab at Duke University working on the calcineurin pathway and developing a novel fungal-specific antifungal through understanding the exact mechanisms of invasive pathogenesis and weak areas to target. The feedback from the host laboratories was extremely positive. Results generated by Calum will be included in a publications. Professor Hube indicated that eh would be happy to host an 8-week scholar in future rounds.
Start Year 2017
 
Description 8-week Summer scholarship partner universities 
Organisation University of Sao Paulo
Country Brazil 
Sector Academic/University 
PI Contribution The MRC CMM offers medical students studying for a BMEDSci the opportunity to spend 8-weeks doing a research project at a leading medical mycology research lab anywhere in the world. The students have to apply for the scholarship and undergo an interview process. Running parallel to this process, the principal investigators (PIs) in the MRC CMM along with colleague PI from another lab (in UK, Europe or international) submit a projects to the MRC CMM for peer review and selection. Successful medical students can select a research project that they like to do during the 8-week summer visit. Students are required to produce a report on completion of their project and record a short U-Tube film outlining their research project and experiences of working in an internationally renowned lab.
Collaborator Contribution The non-MRC CMM PI agree to host the student and supervise the research project during the 8-week visit. In 2016, Professor Bruce Klein from the University of Wisconsin-Madison and Professor Gustavo Goldman from the University of Sao Paulo each hosted a University of Aberdeen medical student in their laboratory - see outputs below.
Impact In 2016, two University of Aberdeen medical students successfully completed their 8-week research projects. The students recorded their experiences which can be viewed on the URL above. Roberta Garau speaks about her experience in Brazil working in Professor Gustavo Goldman's lab at the University of São Paulo studying Aspergillus nidulans, a poorly understood fungal pathogen that infects children with chronic granulomatous disease. Elliott Gemmell tells us about his time working in Professor Bruce Klein's lab at the University of Wisconsin-Madison studying how cells respond to infection with the fungal pathogen, Aspergillus fumigatus - a major cause of infection and mortality in people with compromised immune systems.
Start Year 2016
 
Description 8-week Summer scholarship partner universities 
Organisation University of Wisconsin-Madison
Country United States 
Sector Academic/University 
PI Contribution The MRC CMM offers medical students studying for a BMEDSci the opportunity to spend 8-weeks doing a research project at a leading medical mycology research lab anywhere in the world. The students have to apply for the scholarship and undergo an interview process. Running parallel to this process, the principal investigators (PIs) in the MRC CMM along with colleague PI from another lab (in UK, Europe or international) submit a projects to the MRC CMM for peer review and selection. Successful medical students can select a research project that they like to do during the 8-week summer visit. Students are required to produce a report on completion of their project and record a short U-Tube film outlining their research project and experiences of working in an internationally renowned lab.
Collaborator Contribution The non-MRC CMM PI agree to host the student and supervise the research project during the 8-week visit. In 2016, Professor Bruce Klein from the University of Wisconsin-Madison and Professor Gustavo Goldman from the University of Sao Paulo each hosted a University of Aberdeen medical student in their laboratory - see outputs below.
Impact In 2016, two University of Aberdeen medical students successfully completed their 8-week research projects. The students recorded their experiences which can be viewed on the URL above. Roberta Garau speaks about her experience in Brazil working in Professor Gustavo Goldman's lab at the University of São Paulo studying Aspergillus nidulans, a poorly understood fungal pathogen that infects children with chronic granulomatous disease. Elliott Gemmell tells us about his time working in Professor Bruce Klein's lab at the University of Wisconsin-Madison studying how cells respond to infection with the fungal pathogen, Aspergillus fumigatus - a major cause of infection and mortality in people with compromised immune systems.
Start Year 2016
 
Description AFGrica Centre at the University of Cape Town 
Organisation University of Cape Town
Country South Africa 
Sector Academic/University 
PI Contribution Our new AFGrica Unit in South Africa, in conjunction with the University of Cape Town (UCT), is the world's first international research centre for tackling fungal infections. The £600,000 University of Aberdeen AFGrica Unit will be based at UCT's Institute of Infectious Disease and Molecular Medicine, headed by Professor Valerie Mizrahi and it will give our experts a centre of operations in Africa where they can work in collaboration with UCT experts to establish research programmes that can target the priority areas in fungal diseases that are relevant to the continent. The development supports our ongoing objectives and activities and it also builds on an existing Wellcome Trust-funded Strategic Award (led by the Aberdeen Fungal Group), where PhD students from low and middle-income nations (including Africa) are trained in Aberdeen and other medical mycology Centres in the rest of the UK. Upon obtaining their degree, these students then return home with their new skills to help address critical fungal research and training needs in their own countries.
Collaborator Contribution Our new AFGrica Unit in South Africa, in conjunction with the University of Cape Town (UCT), is the world's first international research centre for tackling fungal infections. The £600,000 University of Aberdeen AFGrica Unit will be based at UCT's Institute of Infectious Disease and Molecular Medicine, headed by Professor Valerie Mizrahi and it will give our experts a centre of operations in Africa where they can work in collaboration with UCT experts to establish research programmes that can target the priority areas in fungal diseases that are relevant to the continent. The development supports our ongoing objectives and activities and it also builds on an existing Wellcome Trust-funded Strategic Award (led by the Aberdeen Fungal Group), where PhD students from low and middle-income nations (including Africa) are trained in Aberdeen and other medical mycology Centres in the rest of the UK. Upon obtaining their degree, these students then return home with their new skills to help address critical fungal research and training needs in their own countries.
Impact The AFGrica Centre was officially opened on 11th August 2017. The overall main of the Centre is to provide a hub for collaborative research and training programmes (between the MRC CMM/AFG and South Africa) that will increase capacity in South Africa and more widely across Africa, to target the priority areas in fungal disease. The programmes will involve MRC CMM/AFG principal investigators and researchers running workshops for basic and clinical researchers at UCT and potentially exchange of PhD students and researchers.
Start Year 2017
 
Description International Scientific Advisory Board membership 
Organisation Duke University
Country United States 
Sector Academic/University 
PI Contribution The MRC CMM Management Board (MB) is responsible for appointing the International Scientific Advisory Board (ISAB) members. The ISAB is independently chaired and composed of 6-8 national and international experts in medical mycology, and will include an MRC representative. Professor Butler chairs the ISAB and will be in post for the first 5 years of the MRC CMM. The ISAB oversees the governance of the MRC CMM. The ISAB membership for the next 5 years is as follows: Profs Geraldine Butler (UCD, Chair), Judith Berman (Tel Aviv University), Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology), Arturo Casadevall (John Hopkins Bloomberg), Tom Harrison (St Georges, MRC representative), Joe Heitman (Duke University), David Lalloo (LSTM) and Dr John Rex (Non-executive Director FG2, ad hoc member).
Collaborator Contribution The ISAB provides the Management Board (MB) with objective, independent advice on our development, scientific strategy and our research, training and translational activities. The ISAB ratifies the appointment of new academic staff to the MRC CMM e.g. senior lecturer, lecturer and early career fellows. The ISAB receives minutes of all MB meetings and annual or other reports The ISAB will meet in person with the MB and MRC CMM principal investigators, students and researchers in year 1 (during the opening conference). The ISAB will undertake formal MRC CMM reviews in years 2 and 4
Impact The ISAB members held their first meeting with the Management Board and Directors on 26th January 2017 and attended the 2-day launch of the MRC CMM on 26th an 27th January 2017
Start Year 2016
 
Description International Scientific Advisory Board membership 
Organisation F2G
Country United Kingdom 
Sector Private 
PI Contribution The MRC CMM Management Board (MB) is responsible for appointing the International Scientific Advisory Board (ISAB) members. The ISAB is independently chaired and composed of 6-8 national and international experts in medical mycology, and will include an MRC representative. Professor Butler chairs the ISAB and will be in post for the first 5 years of the MRC CMM. The ISAB oversees the governance of the MRC CMM. The ISAB membership for the next 5 years is as follows: Profs Geraldine Butler (UCD, Chair), Judith Berman (Tel Aviv University), Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology), Arturo Casadevall (John Hopkins Bloomberg), Tom Harrison (St Georges, MRC representative), Joe Heitman (Duke University), David Lalloo (LSTM) and Dr John Rex (Non-executive Director FG2, ad hoc member).
Collaborator Contribution The ISAB provides the Management Board (MB) with objective, independent advice on our development, scientific strategy and our research, training and translational activities. The ISAB ratifies the appointment of new academic staff to the MRC CMM e.g. senior lecturer, lecturer and early career fellows. The ISAB receives minutes of all MB meetings and annual or other reports The ISAB will meet in person with the MB and MRC CMM principal investigators, students and researchers in year 1 (during the opening conference). The ISAB will undertake formal MRC CMM reviews in years 2 and 4
Impact The ISAB members held their first meeting with the Management Board and Directors on 26th January 2017 and attended the 2-day launch of the MRC CMM on 26th an 27th January 2017
Start Year 2016
 
Description International Scientific Advisory Board membership 
Organisation Johns Hopkins University
Department Johns Hopkins Bloomberg School of Public Health
Country United States 
Sector Academic/University 
PI Contribution The MRC CMM Management Board (MB) is responsible for appointing the International Scientific Advisory Board (ISAB) members. The ISAB is independently chaired and composed of 6-8 national and international experts in medical mycology, and will include an MRC representative. Professor Butler chairs the ISAB and will be in post for the first 5 years of the MRC CMM. The ISAB oversees the governance of the MRC CMM. The ISAB membership for the next 5 years is as follows: Profs Geraldine Butler (UCD, Chair), Judith Berman (Tel Aviv University), Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology), Arturo Casadevall (John Hopkins Bloomberg), Tom Harrison (St Georges, MRC representative), Joe Heitman (Duke University), David Lalloo (LSTM) and Dr John Rex (Non-executive Director FG2, ad hoc member).
Collaborator Contribution The ISAB provides the Management Board (MB) with objective, independent advice on our development, scientific strategy and our research, training and translational activities. The ISAB ratifies the appointment of new academic staff to the MRC CMM e.g. senior lecturer, lecturer and early career fellows. The ISAB receives minutes of all MB meetings and annual or other reports The ISAB will meet in person with the MB and MRC CMM principal investigators, students and researchers in year 1 (during the opening conference). The ISAB will undertake formal MRC CMM reviews in years 2 and 4
Impact The ISAB members held their first meeting with the Management Board and Directors on 26th January 2017 and attended the 2-day launch of the MRC CMM on 26th an 27th January 2017
Start Year 2016
 
Description International Scientific Advisory Board membership 
Organisation Leibniz Association
Department Leibniz Institute for Natural Product Research and Infection Biology
Country Germany 
Sector Public 
PI Contribution The MRC CMM Management Board (MB) is responsible for appointing the International Scientific Advisory Board (ISAB) members. The ISAB is independently chaired and composed of 6-8 national and international experts in medical mycology, and will include an MRC representative. Professor Butler chairs the ISAB and will be in post for the first 5 years of the MRC CMM. The ISAB oversees the governance of the MRC CMM. The ISAB membership for the next 5 years is as follows: Profs Geraldine Butler (UCD, Chair), Judith Berman (Tel Aviv University), Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology), Arturo Casadevall (John Hopkins Bloomberg), Tom Harrison (St Georges, MRC representative), Joe Heitman (Duke University), David Lalloo (LSTM) and Dr John Rex (Non-executive Director FG2, ad hoc member).
Collaborator Contribution The ISAB provides the Management Board (MB) with objective, independent advice on our development, scientific strategy and our research, training and translational activities. The ISAB ratifies the appointment of new academic staff to the MRC CMM e.g. senior lecturer, lecturer and early career fellows. The ISAB receives minutes of all MB meetings and annual or other reports The ISAB will meet in person with the MB and MRC CMM principal investigators, students and researchers in year 1 (during the opening conference). The ISAB will undertake formal MRC CMM reviews in years 2 and 4
Impact The ISAB members held their first meeting with the Management Board and Directors on 26th January 2017 and attended the 2-day launch of the MRC CMM on 26th an 27th January 2017
Start Year 2016
 
Description International Scientific Advisory Board membership 
Organisation Liverpool School of Tropical Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution The MRC CMM Management Board (MB) is responsible for appointing the International Scientific Advisory Board (ISAB) members. The ISAB is independently chaired and composed of 6-8 national and international experts in medical mycology, and will include an MRC representative. Professor Butler chairs the ISAB and will be in post for the first 5 years of the MRC CMM. The ISAB oversees the governance of the MRC CMM. The ISAB membership for the next 5 years is as follows: Profs Geraldine Butler (UCD, Chair), Judith Berman (Tel Aviv University), Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology), Arturo Casadevall (John Hopkins Bloomberg), Tom Harrison (St Georges, MRC representative), Joe Heitman (Duke University), David Lalloo (LSTM) and Dr John Rex (Non-executive Director FG2, ad hoc member).
Collaborator Contribution The ISAB provides the Management Board (MB) with objective, independent advice on our development, scientific strategy and our research, training and translational activities. The ISAB ratifies the appointment of new academic staff to the MRC CMM e.g. senior lecturer, lecturer and early career fellows. The ISAB receives minutes of all MB meetings and annual or other reports The ISAB will meet in person with the MB and MRC CMM principal investigators, students and researchers in year 1 (during the opening conference). The ISAB will undertake formal MRC CMM reviews in years 2 and 4
Impact The ISAB members held their first meeting with the Management Board and Directors on 26th January 2017 and attended the 2-day launch of the MRC CMM on 26th an 27th January 2017
Start Year 2016
 
Description International Scientific Advisory Board membership 
Organisation St George's University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution The MRC CMM Management Board (MB) is responsible for appointing the International Scientific Advisory Board (ISAB) members. The ISAB is independently chaired and composed of 6-8 national and international experts in medical mycology, and will include an MRC representative. Professor Butler chairs the ISAB and will be in post for the first 5 years of the MRC CMM. The ISAB oversees the governance of the MRC CMM. The ISAB membership for the next 5 years is as follows: Profs Geraldine Butler (UCD, Chair), Judith Berman (Tel Aviv University), Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology), Arturo Casadevall (John Hopkins Bloomberg), Tom Harrison (St Georges, MRC representative), Joe Heitman (Duke University), David Lalloo (LSTM) and Dr John Rex (Non-executive Director FG2, ad hoc member).
Collaborator Contribution The ISAB provides the Management Board (MB) with objective, independent advice on our development, scientific strategy and our research, training and translational activities. The ISAB ratifies the appointment of new academic staff to the MRC CMM e.g. senior lecturer, lecturer and early career fellows. The ISAB receives minutes of all MB meetings and annual or other reports The ISAB will meet in person with the MB and MRC CMM principal investigators, students and researchers in year 1 (during the opening conference). The ISAB will undertake formal MRC CMM reviews in years 2 and 4
Impact The ISAB members held their first meeting with the Management Board and Directors on 26th January 2017 and attended the 2-day launch of the MRC CMM on 26th an 27th January 2017
Start Year 2016
 
Description International Scientific Advisory Board membership 
Organisation Tel Aviv University
Country Israel 
Sector Academic/University 
PI Contribution The MRC CMM Management Board (MB) is responsible for appointing the International Scientific Advisory Board (ISAB) members. The ISAB is independently chaired and composed of 6-8 national and international experts in medical mycology, and will include an MRC representative. Professor Butler chairs the ISAB and will be in post for the first 5 years of the MRC CMM. The ISAB oversees the governance of the MRC CMM. The ISAB membership for the next 5 years is as follows: Profs Geraldine Butler (UCD, Chair), Judith Berman (Tel Aviv University), Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology), Arturo Casadevall (John Hopkins Bloomberg), Tom Harrison (St Georges, MRC representative), Joe Heitman (Duke University), David Lalloo (LSTM) and Dr John Rex (Non-executive Director FG2, ad hoc member).
Collaborator Contribution The ISAB provides the Management Board (MB) with objective, independent advice on our development, scientific strategy and our research, training and translational activities. The ISAB ratifies the appointment of new academic staff to the MRC CMM e.g. senior lecturer, lecturer and early career fellows. The ISAB receives minutes of all MB meetings and annual or other reports The ISAB will meet in person with the MB and MRC CMM principal investigators, students and researchers in year 1 (during the opening conference). The ISAB will undertake formal MRC CMM reviews in years 2 and 4
Impact The ISAB members held their first meeting with the Management Board and Directors on 26th January 2017 and attended the 2-day launch of the MRC CMM on 26th an 27th January 2017
Start Year 2016
 
Description International Scientific Advisory Board membership 
Organisation University College Dublin
Country Ireland 
Sector Academic/University 
PI Contribution The MRC CMM Management Board (MB) is responsible for appointing the International Scientific Advisory Board (ISAB) members. The ISAB is independently chaired and composed of 6-8 national and international experts in medical mycology, and will include an MRC representative. Professor Butler chairs the ISAB and will be in post for the first 5 years of the MRC CMM. The ISAB oversees the governance of the MRC CMM. The ISAB membership for the next 5 years is as follows: Profs Geraldine Butler (UCD, Chair), Judith Berman (Tel Aviv University), Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology), Arturo Casadevall (John Hopkins Bloomberg), Tom Harrison (St Georges, MRC representative), Joe Heitman (Duke University), David Lalloo (LSTM) and Dr John Rex (Non-executive Director FG2, ad hoc member).
Collaborator Contribution The ISAB provides the Management Board (MB) with objective, independent advice on our development, scientific strategy and our research, training and translational activities. The ISAB ratifies the appointment of new academic staff to the MRC CMM e.g. senior lecturer, lecturer and early career fellows. The ISAB receives minutes of all MB meetings and annual or other reports The ISAB will meet in person with the MB and MRC CMM principal investigators, students and researchers in year 1 (during the opening conference). The ISAB will undertake formal MRC CMM reviews in years 2 and 4
Impact The ISAB members held their first meeting with the Management Board and Directors on 26th January 2017 and attended the 2-day launch of the MRC CMM on 26th an 27th January 2017
Start Year 2016
 
Description NHS Grampain 
Organisation Grampian University Hospitals NHS Trust
Country United Kingdom 
Sector Hospitals 
PI Contribution The MRC CMM offers fully funded 1-year Clinical Training Fellowships in medical mycology to both clinicians and dentists who have finished their foundation training to help build capacity in the field. Successful candidates will complete a taught element which should introduce them to the field of medical mycology followed by a 7-month research project based in the MRC CMM/Aberdeen Fungal Group. This 1-year should also allow the student, with some mentoring, to formulate the ideas for his/her Clinical PhD fellowship application. The MRC CMM also offers 8-week summer scholarships to medical students studying their BMedSci to do a short research project relevant to medical mycology in a world-renowned medical mycology laboratory. Again the aim of these scholarships is to introduce medical students to the field and the challenges that need tackling.
Collaborator Contribution NHS Staff involved in the Medical Education and Clinical Academic Training have worked with the MRC CMM in the development of the two clinical training programmes, advised on how to target the right candidates, promoted the schemes among their colleagues, networks and Deaneries and participated in the recruitment of candidates. The MR CCMM has worked with the following NHS Grampian staff; Professor Peter Johnston, Associate Postgraduate Dean at NHS Education for Scotland, Scotland Deanery, North Region and will help promote the scheme in Scotland, Professor Phyo Myint, Director of Clinical Academic Training Development: Aberdeen Clinical Academic Training (ACAT) Programmes, Dr Katrina Shearer, Senior Lecturer in Medical Education and Dr Rob Laing, consultant in Infectious Diseases
Impact In February 2017, the MRC CMM interviewed four candidates for the Clinical PhD Fellowships and recruited two of the candidates to start the Fellowship in September 2017. To date, there have been two open calls for the 8-week summer scholarship and four students have been recruited. Two students successfully completed their summer visits/projects in 2016 and two have already ben recruited and have their laboratory placement ready to start in June - July 2017.
Start Year 2016
 
Description PhD Project Collaboration 
Organisation Centre for Genomic Regulation (CRG)
Country Spain 
Sector Academic/University 
PI Contribution Dr Alexander Lorenz, lecturer in Molecular Cell Biology in the School of Medicine, Medical Sciences and Nutrition is the lead PhD supervisor on a MRC CMM funded 3-year PhD project with Professor Neil Gow, MRC CMM/AFG as a co-supervisor. The project explores the "Genetic diversity as a major driver of phenotypic variability and virulence in local outbreak strains of the emerging pathogen Candida auris". The student undertaking the project is Zoe Ross. The world-leading expertise of the Gow lab in understanding fungal cell wall dynamics in combination with the expertise of the Lorenz lab in fungal reproductive processes and genetic inheritance are ideal for addressing this timely and important research on C. auris. Using state-of-the-art molecular genetics, genomics, and microscopical approaches this cross-disciplinary collaboration between the Gow and Lorenz labs with input from Dr Elizabeth Johnston Director of the Mycology Reference Laboratory at Public Health England will help the team understand how the genetic hypervariability between different C. auris isolates arises and how this promotes its phenotypic variability and adaptability. The PhD student will visit Dr Johnson at the PHE (Bristol) for a short visit during the first year for approx. one week to receive training in fungal diagnostics and discussions about C. auris outbreaks in the UK and elsewhere.
Collaborator Contribution Dr Alexander Lorenz, lecturer in Molecular Cell Biology in the School of Medicine, Medical Sciences and Nutrition is the lead PhD supervisor on a MRC CMM funded 3-year PhD project with Professor Neil Gow, MRC CMM/AFG as a co-supervisor. The project explores the "Genetic diversity as a major driver of phenotypic variability and virulence in local outbreak strains of the emerging pathogen Candida auris". The student undertaking the project is Zoe Ross. The world-leading expertise of the Gow lab in understanding fungal cell wall dynamics in combination with the expertise of the Lorenz lab in fungal reproductive processes and genetic inheritance are ideal for addressing this timely and important research on C. auris. Using state-of-the-art molecular genetics, genomics, and microscopical approaches this cross-disciplinary collaboration between the Gow and Lorenz labs with input from Dr Elizabeth Johnston Director of the Mycology Reference Laboratory at Public Health England will help the team understand how the genetic hypervariability between different C. auris isolates arises and how this promotes its phenotypic variability and adaptability. The PhD student will visit Dr Johnson at the PHE (Bristol) for a short visit during the first year for approx. one week to receive training in fungal diagnostics and discussions about C. auris outbreaks in the UK and elsewhere. Provision of new Candida auris strains from emerging outbreaks will also be provided by the Reference laboratory at PHE. New collaboration with Dr Marius Wenzel from the Genome Enabled Biology and Medicine at University of Aberdeen to have 12 C. auris isolates whole genome sequenced using minION nanopore technology. New collaboration with Dr Toni Gabaldón to assemble these genomes and identify genomic features and variations. The PhD student Zoe will visit Dr Gabaldón's laboratory to carry out this work.
Impact During the course of this PhD project results and data will generated by the student to complete and defend a PhD and produce at least 1-2 peer reviewed papers. The student will present data from this project at national conferences and meetings and at least one international conference. The student will also present findings from this project at MRC CMM/AFG laboratory meetings and University of Aberdeen organised events for PhD students. Findings from the project will generate the required base knowledge that will inform experimental strategies probing Candida auris virulence, and generating efficient diagnostic and therapeutic strategies to combat C. auris infections.
Start Year 2017
 
Description PhD Project Collaboration 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Dr Alexander Lorenz, lecturer in Molecular Cell Biology in the School of Medicine, Medical Sciences and Nutrition is the lead PhD supervisor on a MRC CMM funded 3-year PhD project with Professor Neil Gow, MRC CMM/AFG as a co-supervisor. The project explores the "Genetic diversity as a major driver of phenotypic variability and virulence in local outbreak strains of the emerging pathogen Candida auris". The student undertaking the project is Zoe Ross. The world-leading expertise of the Gow lab in understanding fungal cell wall dynamics in combination with the expertise of the Lorenz lab in fungal reproductive processes and genetic inheritance are ideal for addressing this timely and important research on C. auris. Using state-of-the-art molecular genetics, genomics, and microscopical approaches this cross-disciplinary collaboration between the Gow and Lorenz labs with input from Dr Elizabeth Johnston Director of the Mycology Reference Laboratory at Public Health England will help the team understand how the genetic hypervariability between different C. auris isolates arises and how this promotes its phenotypic variability and adaptability. The PhD student will visit Dr Johnson at the PHE (Bristol) for a short visit during the first year for approx. one week to receive training in fungal diagnostics and discussions about C. auris outbreaks in the UK and elsewhere.
Collaborator Contribution Dr Alexander Lorenz, lecturer in Molecular Cell Biology in the School of Medicine, Medical Sciences and Nutrition is the lead PhD supervisor on a MRC CMM funded 3-year PhD project with Professor Neil Gow, MRC CMM/AFG as a co-supervisor. The project explores the "Genetic diversity as a major driver of phenotypic variability and virulence in local outbreak strains of the emerging pathogen Candida auris". The student undertaking the project is Zoe Ross. The world-leading expertise of the Gow lab in understanding fungal cell wall dynamics in combination with the expertise of the Lorenz lab in fungal reproductive processes and genetic inheritance are ideal for addressing this timely and important research on C. auris. Using state-of-the-art molecular genetics, genomics, and microscopical approaches this cross-disciplinary collaboration between the Gow and Lorenz labs with input from Dr Elizabeth Johnston Director of the Mycology Reference Laboratory at Public Health England will help the team understand how the genetic hypervariability between different C. auris isolates arises and how this promotes its phenotypic variability and adaptability. The PhD student will visit Dr Johnson at the PHE (Bristol) for a short visit during the first year for approx. one week to receive training in fungal diagnostics and discussions about C. auris outbreaks in the UK and elsewhere. Provision of new Candida auris strains from emerging outbreaks will also be provided by the Reference laboratory at PHE. New collaboration with Dr Marius Wenzel from the Genome Enabled Biology and Medicine at University of Aberdeen to have 12 C. auris isolates whole genome sequenced using minION nanopore technology. New collaboration with Dr Toni Gabaldón to assemble these genomes and identify genomic features and variations. The PhD student Zoe will visit Dr Gabaldón's laboratory to carry out this work.
Impact During the course of this PhD project results and data will generated by the student to complete and defend a PhD and produce at least 1-2 peer reviewed papers. The student will present data from this project at national conferences and meetings and at least one international conference. The student will also present findings from this project at MRC CMM/AFG laboratory meetings and University of Aberdeen organised events for PhD students. Findings from the project will generate the required base knowledge that will inform experimental strategies probing Candida auris virulence, and generating efficient diagnostic and therapeutic strategies to combat C. auris infections.
Start Year 2017
 
Description PhD Project Collaboration 
Organisation University of Aberdeen
Department Centre for Genome-Enabled Biology & Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Dr Alexander Lorenz, lecturer in Molecular Cell Biology in the School of Medicine, Medical Sciences and Nutrition is the lead PhD supervisor on a MRC CMM funded 3-year PhD project with Professor Neil Gow, MRC CMM/AFG as a co-supervisor. The project explores the "Genetic diversity as a major driver of phenotypic variability and virulence in local outbreak strains of the emerging pathogen Candida auris". The student undertaking the project is Zoe Ross. The world-leading expertise of the Gow lab in understanding fungal cell wall dynamics in combination with the expertise of the Lorenz lab in fungal reproductive processes and genetic inheritance are ideal for addressing this timely and important research on C. auris. Using state-of-the-art molecular genetics, genomics, and microscopical approaches this cross-disciplinary collaboration between the Gow and Lorenz labs with input from Dr Elizabeth Johnston Director of the Mycology Reference Laboratory at Public Health England will help the team understand how the genetic hypervariability between different C. auris isolates arises and how this promotes its phenotypic variability and adaptability. The PhD student will visit Dr Johnson at the PHE (Bristol) for a short visit during the first year for approx. one week to receive training in fungal diagnostics and discussions about C. auris outbreaks in the UK and elsewhere.
Collaborator Contribution Dr Alexander Lorenz, lecturer in Molecular Cell Biology in the School of Medicine, Medical Sciences and Nutrition is the lead PhD supervisor on a MRC CMM funded 3-year PhD project with Professor Neil Gow, MRC CMM/AFG as a co-supervisor. The project explores the "Genetic diversity as a major driver of phenotypic variability and virulence in local outbreak strains of the emerging pathogen Candida auris". The student undertaking the project is Zoe Ross. The world-leading expertise of the Gow lab in understanding fungal cell wall dynamics in combination with the expertise of the Lorenz lab in fungal reproductive processes and genetic inheritance are ideal for addressing this timely and important research on C. auris. Using state-of-the-art molecular genetics, genomics, and microscopical approaches this cross-disciplinary collaboration between the Gow and Lorenz labs with input from Dr Elizabeth Johnston Director of the Mycology Reference Laboratory at Public Health England will help the team understand how the genetic hypervariability between different C. auris isolates arises and how this promotes its phenotypic variability and adaptability. The PhD student will visit Dr Johnson at the PHE (Bristol) for a short visit during the first year for approx. one week to receive training in fungal diagnostics and discussions about C. auris outbreaks in the UK and elsewhere. Provision of new Candida auris strains from emerging outbreaks will also be provided by the Reference laboratory at PHE. New collaboration with Dr Marius Wenzel from the Genome Enabled Biology and Medicine at University of Aberdeen to have 12 C. auris isolates whole genome sequenced using minION nanopore technology. New collaboration with Dr Toni Gabaldón to assemble these genomes and identify genomic features and variations. The PhD student Zoe will visit Dr Gabaldón's laboratory to carry out this work.
Impact During the course of this PhD project results and data will generated by the student to complete and defend a PhD and produce at least 1-2 peer reviewed papers. The student will present data from this project at national conferences and meetings and at least one international conference. The student will also present findings from this project at MRC CMM/AFG laboratory meetings and University of Aberdeen organised events for PhD students. Findings from the project will generate the required base knowledge that will inform experimental strategies probing Candida auris virulence, and generating efficient diagnostic and therapeutic strategies to combat C. auris infections.
Start Year 2017
 
Description PhD Project Collaboration 
Organisation University of Aberdeen
Department Institute of Medical Sciences
Country United Kingdom 
Sector Academic/University 
PI Contribution Professor Gordon (main PhD supervisor) and Nancy Keller, Robert L. Metzenberg and Kenneth B. Raper Professor of Mycology at Wisconsin-Madison (co-supervisor) are collaborating on a MRC CMM funded PhD project " Characterisation of the fungal ligands and physiological functions of MelLec in immunity". Prof essor Keller is names as the external co-supervisor for this project and the PhD student Christina Nikolakopoulou (registered at University of Aberdeen). Professor Brown will bring expertise and intellectual input in immunology while Professor Keller will bring expertise in and intellectual input on molecular genetics and the secondary metabolites of the fungal pathogen(s) Aspergillus species. Professors Brown and Keller will meet (via Skype) with the student at least four times per year to discuss progress of the project. Professor Keller will also be available to provide advice and assistance to the student on a regular basis via email.
Collaborator Contribution Professor Gordon (main PhD supervisor) and Nancy Keller, Robert L. Metzenberg and Kenneth B. Raper Professor of Mycology at Wisconsin-Madison (co-supervisor) are collaborating on a MRC CMM funded 3-year PhD project " Characterisation of the fungal ligands and physiological functions of MelLec in immunity". Professor Keller is names as the external co-supervisor for this project and the PhD student Christina Nikolakopoulou (registered at University of Aberdeen). Professor Brown will bring expertise and intellectual input in immunology while Professor Keller will bring expertise in and intellectual input on molecular genetics and the secondary metabolites of the fungal pathogen(s) Aspergillus species. Professors Brown and Keller will meet (via Skype) with the student at least four times per year to discuss progress of the project. Professor Keller will also be available to provide advice and assistance to the student on a regular basis via email. New collaboration with Professor Matteo Zanda (University of Aberdeen) to chemical synthesis MelLec Ligands and derivatives, including labelled derivatives for cell based assays.
Impact During the course of this PhD project results and data will generated by the student to complete and defend a PhD and produce at least 1-2 peer reviewed papers. The student will present data from this project at national conferences and meetings and at least one international conference. The student will also present findings from this project at MRC CMM/AFG laboratory meetings and University of Aberdeen organised events for PhD students. Our discoveries from a related project have already revealed an important contribution of polymorphisms of this receptor during stem cell transplant in patients, which has diagnostic and therapeutic implications. Understanding the role of this receptor in immunity to other fungal species and the identification of further ligands, will provide important new insights that may have further translational potential. Any translational outcome from the work proposed here will be explored with the help of existing structures provided by the University of Aberdeen such as the· Kosterlitz Centre for Therapeutics and the University of Aberdeen Research and Innovation team.
Start Year 2017
 
Description PhD Project Collaboration 
Organisation University of Aberdeen
Department School of Medicine, Medical Sciences and Nutrition
Country United Kingdom 
Sector Academic/University 
PI Contribution Dr Alexander Lorenz, lecturer in Molecular Cell Biology in the School of Medicine, Medical Sciences and Nutrition is the lead PhD supervisor on a MRC CMM funded 3-year PhD project with Professor Neil Gow, MRC CMM/AFG as a co-supervisor. The project explores the "Genetic diversity as a major driver of phenotypic variability and virulence in local outbreak strains of the emerging pathogen Candida auris". The student undertaking the project is Zoe Ross. The world-leading expertise of the Gow lab in understanding fungal cell wall dynamics in combination with the expertise of the Lorenz lab in fungal reproductive processes and genetic inheritance are ideal for addressing this timely and important research on C. auris. Using state-of-the-art molecular genetics, genomics, and microscopical approaches this cross-disciplinary collaboration between the Gow and Lorenz labs with input from Dr Elizabeth Johnston Director of the Mycology Reference Laboratory at Public Health England will help the team understand how the genetic hypervariability between different C. auris isolates arises and how this promotes its phenotypic variability and adaptability. The PhD student will visit Dr Johnson at the PHE (Bristol) for a short visit during the first year for approx. one week to receive training in fungal diagnostics and discussions about C. auris outbreaks in the UK and elsewhere.
Collaborator Contribution Dr Alexander Lorenz, lecturer in Molecular Cell Biology in the School of Medicine, Medical Sciences and Nutrition is the lead PhD supervisor on a MRC CMM funded 3-year PhD project with Professor Neil Gow, MRC CMM/AFG as a co-supervisor. The project explores the "Genetic diversity as a major driver of phenotypic variability and virulence in local outbreak strains of the emerging pathogen Candida auris". The student undertaking the project is Zoe Ross. The world-leading expertise of the Gow lab in understanding fungal cell wall dynamics in combination with the expertise of the Lorenz lab in fungal reproductive processes and genetic inheritance are ideal for addressing this timely and important research on C. auris. Using state-of-the-art molecular genetics, genomics, and microscopical approaches this cross-disciplinary collaboration between the Gow and Lorenz labs with input from Dr Elizabeth Johnston Director of the Mycology Reference Laboratory at Public Health England will help the team understand how the genetic hypervariability between different C. auris isolates arises and how this promotes its phenotypic variability and adaptability. The PhD student will visit Dr Johnson at the PHE (Bristol) for a short visit during the first year for approx. one week to receive training in fungal diagnostics and discussions about C. auris outbreaks in the UK and elsewhere. Provision of new Candida auris strains from emerging outbreaks will also be provided by the Reference laboratory at PHE. New collaboration with Dr Marius Wenzel from the Genome Enabled Biology and Medicine at University of Aberdeen to have 12 C. auris isolates whole genome sequenced using minION nanopore technology. New collaboration with Dr Toni Gabaldón to assemble these genomes and identify genomic features and variations. The PhD student Zoe will visit Dr Gabaldón's laboratory to carry out this work.
Impact During the course of this PhD project results and data will generated by the student to complete and defend a PhD and produce at least 1-2 peer reviewed papers. The student will present data from this project at national conferences and meetings and at least one international conference. The student will also present findings from this project at MRC CMM/AFG laboratory meetings and University of Aberdeen organised events for PhD students. Findings from the project will generate the required base knowledge that will inform experimental strategies probing Candida auris virulence, and generating efficient diagnostic and therapeutic strategies to combat C. auris infections.
Start Year 2017
 
Description PhD Project Collaboration 
Organisation University of Wisconsin-Madison
Country United States 
Sector Academic/University 
PI Contribution Professor Gordon (main PhD supervisor) and Nancy Keller, Robert L. Metzenberg and Kenneth B. Raper Professor of Mycology at Wisconsin-Madison (co-supervisor) are collaborating on a MRC CMM funded PhD project " Characterisation of the fungal ligands and physiological functions of MelLec in immunity". Prof essor Keller is names as the external co-supervisor for this project and the PhD student Christina Nikolakopoulou (registered at University of Aberdeen). Professor Brown will bring expertise and intellectual input in immunology while Professor Keller will bring expertise in and intellectual input on molecular genetics and the secondary metabolites of the fungal pathogen(s) Aspergillus species. Professors Brown and Keller will meet (via Skype) with the student at least four times per year to discuss progress of the project. Professor Keller will also be available to provide advice and assistance to the student on a regular basis via email.
Collaborator Contribution Professor Gordon (main PhD supervisor) and Nancy Keller, Robert L. Metzenberg and Kenneth B. Raper Professor of Mycology at Wisconsin-Madison (co-supervisor) are collaborating on a MRC CMM funded 3-year PhD project " Characterisation of the fungal ligands and physiological functions of MelLec in immunity". Professor Keller is names as the external co-supervisor for this project and the PhD student Christina Nikolakopoulou (registered at University of Aberdeen). Professor Brown will bring expertise and intellectual input in immunology while Professor Keller will bring expertise in and intellectual input on molecular genetics and the secondary metabolites of the fungal pathogen(s) Aspergillus species. Professors Brown and Keller will meet (via Skype) with the student at least four times per year to discuss progress of the project. Professor Keller will also be available to provide advice and assistance to the student on a regular basis via email. New collaboration with Professor Matteo Zanda (University of Aberdeen) to chemical synthesis MelLec Ligands and derivatives, including labelled derivatives for cell based assays.
Impact During the course of this PhD project results and data will generated by the student to complete and defend a PhD and produce at least 1-2 peer reviewed papers. The student will present data from this project at national conferences and meetings and at least one international conference. The student will also present findings from this project at MRC CMM/AFG laboratory meetings and University of Aberdeen organised events for PhD students. Our discoveries from a related project have already revealed an important contribution of polymorphisms of this receptor during stem cell transplant in patients, which has diagnostic and therapeutic implications. Understanding the role of this receptor in immunity to other fungal species and the identification of further ligands, will provide important new insights that may have further translational potential. Any translational outcome from the work proposed here will be explored with the help of existing structures provided by the University of Aberdeen such as the· Kosterlitz Centre for Therapeutics and the University of Aberdeen Research and Innovation team.
Start Year 2017
 
Description PhD Project Collaboration (2018 - 2021) 
Organisation University of Oxford
Department Kennedy Institute of Rheumatology
Country United Kingdom 
Sector Academic/University 
PI Contribution Professor Gordon (main PhD supervisor) and Professor Fiona Powrie, University of Oxford (co-supervisor) are collaborating on a MRC CMM funded PhD project "Dendritic cell lectin-like receptors and their role in anti-fungal adaptive immunity ". Professor Powrie is named as the external co-supervisor for this project and the PhD student Emily Speakman (registered at University of Aberdeen). Professor Brown will bring expertise and intellectual input in immunology while Professor Powrie will bring expertise in and intellectual input on gastrointestinal immunology. This project is focused on further expanding our understanding of the functions of newly discovered C-type lectin receptors that play key roles in antifungal immunity in the GI tract. Professors Brown and Powrie will meet (via Skype) with the student at least four times per year to discuss progress of the project. Professor Powrie will also be available to provide advice and assistance to the student on a regular basis via email.
Collaborator Contribution This project is focused on further expanding our understanding of the functions of newly discovered C-type lectin receptors that play key roles in antifungal immunity in the GI tract. Professor Powrie will bring expertise and intellectual know how in gastrointestinal immunology. Professor Powrie is also a co-supervisor of the PhD student and as such will be involved in regular progress meetings between the lead supervisor (G Browns) and the student.
Impact During the course of this PhD project results and data will generated by the student to complete and defend a PhD and produce at least 1-2 peer reviewed papers. The student will present data from this project at national conferences and meetings and at least one international conference. The student will also present findings from this project at MRC CMM/AFG laboratory meetings and University of Aberdeen organised events for PhD students. Finding from the project will further understanding of the functions of newly discovered C-type lectin receptors that play key roles in antifungal immunity in the Gastrointestinal tract.
Start Year 2018
 
Description PhD Project Collaboration (2018- 2021) 
Organisation Imperial College London
Department National Heart & Lung Institute (NHLI)
Country United Kingdom 
Sector Academic/University 
PI Contribution Professor Adilia Warris (main supervisor, MRC CMM) is collaborating with Dr Darius Armstrong-James (co-supervisor, Imperial College) on a MRC CMM PhD studentship titled "Preventing Aspergillus-induced inflammation in cystic fibrosis to reduce airway disease". Additionally, Dr Neil Vargesson (University of Aberdeen) is also a collaborator on this project. Prof. Adilia Warris is the main supervisor of the PhD student, Alexander Currie and brings clinical expertise in Aspergillus disease in paediatric patients, host-fungus interactions with a focus on A. fumigatus; neutrophils, peripheral blood mononuclear cells, innate antifungal immunity and inflammation.
Collaborator Contribution Dr Darius Armstrong-James, is the external co-supervisor of the PhD students and brings clinical expertise in Aspergillus disease in transplant patients and those with cystic fibrosis and other chronic pulmonary diseases; host-fungus interactions with a focus on A. fumigatus; macrophages, cell death pathways and immunotherapy. The proposed murine experiments will be performed by the student at Imperial College London (under supervision of Armstrong-James). As the murine experiments will be used to validate key in vitro findings derived from our stimulation studies, it is expected that the student will spend 4 - 6 months in Imperial College London. This period will take place during months 21 - 27 in the 3-year period (11-16% of total time). Dr. Vargesson is a developmental biologist who also runs a Home Office approved zebrafish facility at the University of Aberdeen. His role will be to provide initial training for the student how to breed and inject the zebrafish, and to provide expert input on the zebrafish biology and the use specific fluorescent reporter lines visualizing neutrophils and/or macrophages.
Impact During the course of this PhD project results and data will generated by the student to complete and defend a PhD and produce at least 1-2 peer reviewed papers. The student will present data from this project at national conferences and meetings and at least one international conference. The student will also present findings from this project at MRC CMM/AFG laboratory meetings and University of Aberdeen organised events for PhD students.
Start Year 2018
 
Title Antibody Molecules and Uses Thereof 
Description Monoclonal antibodies (mAbs) are highly specific proteins produced naturally by the immune system to fight disease. These targeted, low toxicity agents have revolutionised the way we diagnose and treat many diseases, particularly in the areas of cancer and autoimmunity however, they have yet to be fully exploited I n the setting of fungal infections. Dr Fiona Rudkin's, an RSE Enterprise Fellow (2017) research has focused on developing a diverse portfolio of IP-protected fully human mAbs against Candida - one of the 'Big Four' major human fungal pathogens. Following validation of these mAbs in early stage diagnostic and therapeutic settings, Dr Rudkin is now leading the commercialisation of this research which will result in the creation of mycoBiologics - a new spin out company focused on generating fully human mAbs to combat the urgent problems in diagnosing and treating life-threatening fungal infections. 
IP Reference US2018037640 
Protection Patent application published
Year Protection Granted 2017
Licensed No
Impact Following validation of these mAbs in early stage diagnostic and therapeutic settings, Dr Rudkin is now leading the commercialisation of this research which will result in the creation of mycoBiologics - a new spin out company (in 2019) focused on generating fully human mAbs to combat the urgent problems in diagnosing and treating life-threatening fungal infections. Dr Rudkin received a Royal Society of Edinburgh Enterprise Fellowship (started April 2017) to take the commercialisation of this research forward.
 
Title Fungal Invaders game 
Description Fungal Invaders game was co-developed by researchers in the MRC CMM/AFG (led by Professor Neil Gow), Game Dr and Monocool Interactive and launched at our Killer Fungus Summer Science Exhibition in June 2016. In this amazing game you will use a range of powerful antifungal weapons to fight off different fungal invaders as they try to infect the human body! Fungi are special microbes that can infect the human body. We use antibiotics to kill fungi and fight these nasty infections. Sometimes fungi can evolve resistance to antibiotics and these infections are very difficult to treat and need lots of different antibiotics. If you know how to play Space Invaders, then you already know how to play Fungal Invaders! All the Fungal Invaders are based on real infectious fungi, and you will be fighting against: • Crypto-Killer • Fungi-Foe • Myco-Monster If that wasn't hard enough, not all your antifungal weapons can kill all of the invaders - - so think before you fire that syringe! 
Type Of Technology Software 
Year Produced 2016 
Impact The Fungal Invaders game was launched to coincide with our Killer Fungal exhibition showcased at the Royal Society Summer Science Exhibition in 2016 which was attended by over 14,000 people. The game is freely available to down load from the app store and google play. This game was included in the Killer Fungus Outbreak exhibition at the Manchester Science Festival 2017 - Platform to Discovery which was jointly organised with the University of Manchester and attended by 655 adults and 635 children. 
URL http://www.killerfungus.org
 
Title Killer Fungus: Evolution game 
Description Killer Fungus: Evolution was co-developed by scientists in the MRC CMM/AFG (led by Professor Neil Gow), Game Dr and Monocool Interactive with artwork by Siam Colvine. The game was launched at our Killer Fungus exhibition showcased at the Royal Society Summer Science exhibition in June 2016. Some Fungi are special microbes that infect the human body. During infection fungi can use special superpowers or skills to help them avoid or damage our immune system! This helps them survive for longer and cause nasty infections! In this amazing game you will put a range of these skills to the test and find out exactly what combinations are needed to create a super fungus that can survive immune cell attack! Upgrade and mix and match between;: • Grapple • Shield • Stealth • Decoys • Toxins • Morph (Warning some of the immune cell enemies like to eat your fungus! How will you escape?) 
Type Of Technology Software 
Year Produced 2016 
Impact The Killer Fungus: Evolution game was launched to coincide with our Killer Fungal exhibition showcased at the Royal Society Summer Science Exhibition in 2016 which was attended by over 14,000 people. The game is freely available to down load from the app store and google play. This game was included in the Killer Fungus Outbreak exhibition at the Manchester Science Festival 2017 - Platform to Discovery which was jointly organised with the University of Manchester and attended by 655 adults and 635 children. 
URL http://www.killerfungus.org/
 
Description Roslin Institute Seminar Series 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Dr Elizabeth Ballou, principal investigator in MRC CMM was invited to give a talk at the Roslin Institute in Edinburgh as part of its seminar series in September 2016
Year(s) Of Engagement Activity 2016
 
Description 13th International Symposium on the Genetics of Industrial Microorganisms, Wuhan, China 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Carol Munro was an invited speaker at the 13th International Symposium on the Genetics of Industrial Microorganisms, Wuhan, China in October 2016. Professor Munro's talk was entitles "The yeast cell wall as an antifungal drug target"
Year(s) Of Engagement Activity 2016
 
Description 14th Oxford Infection and Immunity Course 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Adilia Warris, Deputy Director of Clinical Training in MRC CMM, gave a lecture on "How to spot invasive fungal disease in paediatrics". The course runs from July 11-13, 2016 in Oxford, UK. and the audience is comprised of national and international medical trainees, fellows and consultants in paediatric infectious diseases. Professor Warris participates on this course on an annual basis.
Year(s) Of Engagement Activity 2016
 
Description 2nd EMBO Workshop on AIDS-related Mycoses 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Gordon Brown, Director of MRC CMM oversees the organisation and delivery of this biennial EMBO workshop which is held in Cape Town South Africa. Research staff and students from MRC CMM also participate in this workshop.
Year(s) Of Engagement Activity 2016
 
Description After Dinner Speech - International Women's Day Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Dr Alex Brand, principal investigator in MRC CMM has been invited to give the after dinner speech at the International Women's Day Conference held at the University of Aberdeen on 8th March 2017.
Year(s) Of Engagement Activity 2017
 
Description After School Club (Towie Primary - Aberdeenshire) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Dr Jude Bain, Post doc in MRC CMM) covered the after school club (1hr) on 21st May 2018. Jude introduced the children to microbiology by getting them to swab items and streak the swabs on petri dishes and media. She incubated these and took pictures of the resulting microbes for the children to view at the following week's club.
Year(s) Of Engagement Activity 2018
 
Description Annual Fungal Updates at St Bartholomew's Hospital Meeting, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Neil Gow was invited to give a talk at the 2016 meeting on the Killer Fungus Exhibition which was held at the Royal Society Summer Science Exhibition in July 2016.
Year(s) Of Engagement Activity 2016
 
Description Café Scientifique - Battling the Killer Fungus 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Professors Gordon Brown and Neil Gow did an interactive talk on "Battling the Killer Fungus" to a general public audience at a Café Scientifique night on 20th September 2017. The talk was followed by a questions and answers. The talk was went out live on Facebook which has now been uploaded to our website under Public Events (https://www.abdn.ac.uk/cmm/public-engagement/public-events.php).
Year(s) Of Engagement Activity 2017
URL https://www.abdn.ac.uk/cmm/public-engagement/public-events.php
 
Description Canterbury: School of Biosciences annual lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Neil Gow was invited to talk at the School of Biosciences Annual Lecture at the University of Kent.
Year(s) Of Engagement Activity 2016
 
Description Cell Block Science - National Public Engagement Agenda 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Members of the MRC CMM, lecturer, PhD students and postdocs visited the HMP Grampain in Peterhead for the day - demonstrated DNA extraction to individual groups of men and women prisoners. The event was organised in collaboration with HMP Grampian prison learning centre and Uni of St Andrew's.
Year(s) Of Engagement Activity 2018
 
Description Clinical Mycology; from the bench to the bedside: 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Adilia Warris was invited to speak at the Clinical Mycology; from the bench to the bedside: Epidemiology of Invasive Fungal Disease in Paediatrics & Management of Invasive Fungal Disease in Paediatrics. February 19-22, 2017. Berg & Dal, the Netherlands. The audience mainly comprised of international medical doctors.
Year(s) Of Engagement Activity 2017
 
Description Connect Event organised by University of Aberdeen Alumni Relations 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Supporters
Results and Impact Exhibition stand in the Institute of Medical Sciences with focus on the Clinical challenges of human fungal infections, breath of research in the MRC CMM, international links and researcher and clinical training provided and the translational work happening in the MRC CMM. Also organised laboratory tours including MRC CMM labs, Microscopy and Flow Cytometry. The event was led by Profs Al Brown & Adilia Warrris and Drs Deborah Lockhart and Fiona Rudkin plus PhD students and postdoctoral researchers. Written feedback was gathered by Alumni relations with very positive comments. The post-event surveys also calculate a quantitative score known as the Net Promoter Score (NPS) and our event scored 90, which is excellent.
Year(s) Of Engagement Activity 2017
 
Description Doors Open Sept 2018 - Institute of Medical Sciences 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Dr Donna MacCallum hosted an exhibition stand called "All the fun of the fungal fair".
Year(s) Of Engagement Activity 2018
 
Description Doors Open at Institute of Medical Sciences (IMS) University of Aberdeen 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Hosted an exhibition stand and did laboratory tours at 2017 IMS Doors Open. We had over 100 people, including children do the lab tours of the MRC Centre and Core Facilities e.g. Microscopy and Flow Cytometry labs. The stand and tours featured three of our Principal Investigators (Gordon Brown, Neil Gow and Heather Wilson) in addition to many PhD students and postdoctoral researchers. Feedback collected from visitors was very positive. We were very pleased at the number of people that visited and wanted to do laboratory tours, The increase in numbers from previous years' was probably due to an increased effort to publicise the event via Facebook live interviews.
Year(s) Of Engagement Activity 2017
 
Description Doors Open at Institute of Medical Sciences (IMS) University of Aberdeen 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The Doors Open event (10th Sept 2016) at the IMS was open to the general public of all ages. We hosted an interactive exhibition stand to highlight the importantce and challenges of fungal disease and conducted tours of the MRC Centre for Medical Mycology (MRC CMM) labs and facilities. Feedback from visitors showed that 71.5% of the visitors completely enjoyed the interactive activities on the exhibition stand and lab tours. 92.9% of visitors believed that research into fungal infections in humans was important.
Year(s) Of Engagement Activity 2016
URL http://www.abdn.ac.uk/cmm/public-engagement/public-events.php
 
Description Dornoch Academy School visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Dr Alex Brand was invited to give a schools lecture to high school pupils at Dornoch Academy in the highlands academy. Dr Brand spoke about her research and why is was important. She also spoke about her career pathway.
Year(s) Of Engagement Activity 2017
 
Description European Researchers' Night 2016 at Aberdeen Science Centre 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Explorathon16 - Scotland's edition of European Researchers' Night, is a yearly celebration of European research which happened on the 30 September 2016 in 250 cities across Europe. Our fungal experts spent the evening at Aberdeen Science Centre chatting with both children and adults about the positive and negative influence fungi have on our daily lives. Visitors were particularly excited to look down the microscope at the multiple shapes and forms fungi can take.
In the arcade corner, "children" of all ages had the opportunity to test several video games developed by the University of Aberdeen, including our two game apps: "Fungal invaders" and "Killer fungus: Evolution". Duncan Wilson (MRC CMM principal investigator) took part in a lively debate with other researchers and members of the public on the role of digital games and apps as educational tools.
Year(s) Of Engagement Activity 2016
URL http://www.abdn.ac.uk/cmm/public-engagement/public-events.php
 
Description Explorathon 18 (Aberdeen) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Drs Donna MacCallum, and Alex Brand, students and Postdocs from the MRC CMM hosted an exhibition stand outside Marks and Spenser's in Aberdeen City.
Year(s) Of Engagement Activity 2018
 
Description Explorathon17 and UK Fungus Day 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact On 29th September 2017 we run joint events for Explorathon17 (Scotland's edition of European Researchers' Night) and UK Fungus Day.
Our day team, led by Dr Alexandra Brand set up a display in Aberdeen Gold Zone (St Nicholas Square) showing how "Fantastic Fungi" provide many of our daily products, from food & drink, to medicines and even washing powder. In the evening Professor Alistair Brown, Dr Donna MacCallum and with help from some of our students and postdocs were at Aberdeen Science Centre, showing children and their parents around the "Kingdom of Fungi" exhibition and explaining through exciting activities that fungi can also cause infections and have a negative impact on our lives.
Year(s) Of Engagement Activity 2017
URL https://www.abdn.ac.uk/cmm/public-engagement/public-events.php
 
Description Frightening Fungi at Aberdeen Train Station - MRC Festival of Medical Research 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact MRC Festival June 2018 - the Director, students and postdoctoral researchers participated in an interactive exhibit at Aberdeen Train station. The exhibit consisted of a large cardboard cut out of a human body with magnetic fungi highlighting the major areas of fungal infection, 3D fungal models, interactive games for children (fungal skittles), etc.
Year(s) Of Engagement Activity 2018
 
Description Fungibrain EU-funded innovative training network Summer School, Aberdeen 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Professor Carol Munro was an invited speaker at the Fungibrain EU-funded innovative training network Summer School, Aberdeen in September 2016 on "The challenges facing antifungal drug design and development."
Year(s) Of Engagement Activity 2016
 
Description Gilead Antifungal Information Network learning centre 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Adilia Warris was invited to give a talk on Antifungal stewardship in a paediatric setting & Clinical implications of azole-resistant Aspergillus fumigatus. The target audience was medical doctors and those in training.
Year(s) Of Engagement Activity 2016
URL http://gain-info.co.uk/learning-centre
 
Description Gilead Medical Affairs International Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Professor Adilia Warris gave a talk on the "Treatment of Invasive Fungal Infections in Paediatric" at the conference that was held in London. The main attendees were Gilead Medical Affairs Staff.
Year(s) Of Engagement Activity 2017
 
Description Girl Guides 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Dr Janet Willment, a senior scientist in the MRC CMM and a volunteer with a local Girl Guides group in Aberdeen, arranged an "Learn about microbiology" event for this Girl Guides group in September 2016. This interactive event involved stations set up showing Saccharomyces fermentation & stains, yoghurt bacterial stains & oral swabs. The children took swabs from various surfaces and plated on nutrient agar plates and examined these for microbial growth using a microscope and magnifying glasses and had to answer questions. Ideas for the event were taken from the Microscopes for Schools website.
Year(s) Of Engagement Activity 2016
 
Description Hall of Mayhem - May Festival at University of Aberdeen 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Dr Donna MacCallum along with MRC CMM students and Postdoctoral researchers hosted an exhibition stand at the May Festival Hall of Mayhem. The Hall of Mayhem is targeted specifically at school children. Participants were able to extract DNA and making a DNA bracelet. There was also a workshop on what lives in the gut. The Hall of Mayhem activities, especially extracting DNA activity is very popular with the school children and Dr MacCallum was invited to do this activity at an exhibition stand for the School of Medicine, Medical Sciences and Nutrition at the Doors Open Day in September 2017.
Year(s) Of Engagement Activity 2017
 
Description House of Commons - University of Aberdeen - showcasing University entrepreneurs 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Dr Fiona Rudkin from MRC CMM/AFG was invited as part of the University's of Aberdeen delegation of entrepreneurs to a meet and greet showcasing event at the House of Commons on 26th February 2018.
Year(s) Of Engagement Activity 2018
 
Description I'm a Scientist 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact MRC Festival Zone - I'm a Scientist - competition to find the favorite researcher and support staff- open to secondary schools - Dr Donna MacCallum, MRC CMM was one of 25 chosen out 60 to participate. There are specific criteria for participating schools - see MRC Life June/July 2018 for further details. Secondary school students can ask questions about the scientists research, career, hobbies etc. Teachers can request Live Class Room chats.
Year(s) Of Engagement Activity 2018
 
Description ImResFun EU-funded innovative training network final meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Carol Munro, principal investigator in the MRC CMM gave a keynote talk at the ImResFun EU-funded innovative training network final meeting on "The fungal cell wall: a dynamic organelle with roles in pathogenesis, drug susceptibility, and a target for therapeutics and diagnostics."
Year(s) Of Engagement Activity 2017
 
Description Immunobiology Seminar at University of Glasgow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Gordon Brown was invited to present at the Immunobiology Seminar hosted by the University of Glasgow on 2-3rd November 2016.
Year(s) Of Engagement Activity 2016
 
Description Ingenious Women 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Dr Alex Brand, principal investigator in MRC/CMM/AFG gave a lunchtime talk at the inaugurating meeting of 'Ingenious Women' - Aberdeen Group on 15th March 2017. The event was held at the Sir Duncan Rice Library at University of Aberdeen for early career scientists from both the University of Aberdeen and Robert Gordon University Aberdeen.
Year(s) Of Engagement Activity 2017
 
Description Ingenious Women in STEM (Feb 2019) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Designed specifically for women working in STEM roles, this networking event is open to all women of all career stages who are interested in reflecting on their careers and building their networks. Dr Fiona Rudkin, CEO of mycoBiologics was an invited speaker at the event to talk about her research and formation of spin out company mycoBiologics.
Year(s) Of Engagement Activity 2018
 
Description International Women's Day 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Dr Alex Brand, principal investigator in the MRC CMM/AFG gave an after-dinner talk to women business leaders and university staff about science careers and an overview of World Economic Forum monitoring progress of women in society. The event was held to mark International Women's Day at the University of Aberdeen on 7th March 2018.
Year(s) Of Engagement Activity 2017
 
Description Killer Fungus exhibition 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Hosted the Killer Fungus exhibition at the Royal Society Summer Science exhibition in London from 4-10th July 2016 - one of 22 successful applications to the Royal Society. The event was attended by over 14,000 people, including 140 school groups. The Killer Fungus exhibition received media coverage from BBC News Health (online), CNN, the Naked Scientist, the Daily Mail and New Scientist. The exhibit consisted of interactive video games (Fungal Invaders and Killer Fungus: Evolution), an interactive mannequin showing regions of the body susceptible to fungal infection, 3D models of microscopic pathogenic fungi, short films describing research by students and staff and arts and crafts. Based on visitor feedback, 73% of visitors found the activities extremely/very informative, and 78% found them extremely/very good fun. The percentage of people who were extremely/very aware of the role of fungi in human disease increased from 17.8% before visiting the exhibition to 81% after visiting the exhibition. Following the success of our Killer Fungus exhibition, we were invited by the Royal Society to participate in its satellite exhibition stand at the Manchester Science Festival in September 2016. Unfortunately, we were unable to raise the resources to participate in 2016 but are in talks with the Royal Society to participate in October 2017.
Year(s) Of Engagement Activity 2016
URL https://royalsociety.org/science-events-and-lectures/summer-science-exhibition/
 
Description Lecture to MSc students Oxford University 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact In November 2016, Professor Gordon Brown was invited to give a lecture on medical mycology and fungal immunology to MSc students at Oxford University. This is now an annual event for Professor Brown.
Year(s) Of Engagement Activity 2016
 
Description Lecture to MSc students at University of Cape Town, South Africa 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In November 2016, Professor Gordon Brown gave a lecture to MSc students on medical mycology and fungal immunology at the University of Cape Town. Professor Brown is an adjunct Professor and runs a research lab in the Institute of Infectious Disease and Moleular Medicine at the University of Cape Town
Year(s) Of Engagement Activity 2016
 
Description Local business and charity groups 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Industry/Business
Results and Impact Professor Neil Gow was invited to give a presentation on fungal infectious diseases, the research and challenges to a number of closed groups: (1) Bon Accord Ladies Probus Club - Aberdeen on 3rd May 2017 in Community Hall in Aberdeen. This is a professional and business club of women in Aberdeen and (2) The National Trust of Scotland members club on 1st September 2017 at the Aberdeen Cricket Club.
Year(s) Of Engagement Activity 2017
 
Description MRC Centre for Medical Mycology Brochure 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact To mark the official launch of the MRC CMM on 26-27th January 2017, we produced a brochure targeted at a range of potential stakeholders. The brochure provides an overview of the Centre, its vision and strategic need and profiles the principal investigators and their world leading research teams. The brochure can be downloaded from our website - see direct link at URL below.
Year(s) Of Engagement Activity 2016
URL http://www.abdn.ac.uk/cmm/about/index.php
 
Description MRC Centre for Medical Mycology website, Twitter and Facebook 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The MRC CMM now has a dedicated website in place since the start date. The website provides information on the research conducted within the Centre for both a lay audience and the scientific community, through the use of U-Tube videos, podcasts, individual profiles of research staff and students. The website is also used to advertise our research and training opportunities, promote our public engagement activities, and highlight media coverage. Researchers and the public can also follow our activities and updates by following our Twitter account (@MRCcmm) and Facebook page (Aberdeen Fungal Group at MRC Centre for Medical Mycology).
Year(s) Of Engagement Activity 2016
URL http://www.abdn.ac.uk/cmm/
 
Description MRC Festival 2017 - Art Competition for primary schools 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Art competition called "Magical Mushrooms and Frightening Fungi" sent to Head teachers of primary schools (classes P4-P7) in Aberdeen City on 25th April with a closing date of 31st May. We asked primary schools in Aberdeen to create an image capturing what they love about fungi. Pupils visited our Fungal Facts page on our website to learn more about the different types of fungi and to look at inspiring images. We received over 80 entries from Seaton, Woodside, Kirkhill, Albyn, Cults and Milltimber primary schools from different age groups. The judges were Dame Professor Anne Glover and Dr Karen McArdle (University of Aberdeen) and Ms Shelagh Swanson( local artist). The art work was outstanding and it was difficult for the judges to make their decisions. The award went jointly to Seaton Primary 4 and Woodside Primary 4 classes. We visited them in their final week of term to award the prizes, which included a trophy and a £200 voucher per school to buy science equipment. Both winning classes will visit the Kingdom of Fungi exhibition at the Aberdeen Science Centre in Spring 2018. In addition to the interactive activities in the exhibition, the pupils will get a chance to see a working laboratory. The other schools each received a £50 Amazon voucher for their amazing artwork and interest in the subject.
Year(s) Of Engagement Activity 2017
URL https://www.abdn.ac.uk/cmm/public-engagement/public-events.php
 
Description MRC Insight Blog - UK Fungus Day 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact To mark UK Fungus Day 2017 on the 9th October 2017, our 2017 MRes in Medical Mycology students and clinicians wrote a blog for MRC Insight based on the UK Fungus Day 2017, 5 themes called "5 reasons why we study fungi". The authors of the blog are Dr Joanne Calley, Miss Emily Speakman, Dr Catherine Mark and Mr Alexander Currie.
Year(s) Of Engagement Activity 2017
URL http://www.insight.mrc.ac.uk/2017/10/09/five-reasons-fungal-disease
 
Description MRC Life - feature on Dr Fiona Rudkin and mycoBiologics 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Article in MRC Life October/November 2018 issue titled " Innovative business start-up shortlisted for award" - highlighting that mycoBiologics and Dr Fiona Rudkin had made it to the final of 2018 Converge Challenge, narrowly missing out on first prize.
Year(s) Of Engagement Activity 2018
 
Description MRC Scottish Parliament Event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Policymakers/politicians
Results and Impact Professor Gordon Brown, Dr Fiona Rudkin and Dr Barbara Gorgoni joined other MRC funded Centres, Units and Institutes at Holyrood to exhibit the research and translational activities (mycoBiologics) that are happening in the MRC CMM. This event was hosted in the evening specifically for MSPs, policymakers and other invited stakeholders. The event was highly successful and there was excellent interaction with MSPs for both Gordon and Fiona.
Year(s) Of Engagement Activity 2018
 
Description Mad March Science Festival - organised by Cromar Futures Group for British Science Week 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Cromar Future Group, who run afterschool science clubs for upper Deeside schools. They have organised a festival of science events: Mad March Science Festival, 26th Feb - 11th March, which overlaps with the start of British Science Week 2018. As a part of the festival, brochure here https://www.flipgorilla.com/p/25441453291340247/show
Dr Jube Bain, a postdoctoral researcher in the MRC CMM/Aberdeen Fungal Group will run a stall on "Fungi - Hidden Killers" on March 11th 2018. It is for the Donside festival held at Towie primary. The number of visitors was small but the idea was to promote science to even these remote parts of rural Aberdeenshire.
Year(s) Of Engagement Activity 2017
 
Description Manchester Science Festival - Killer Fungus Outbreak 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact On 24th October 2017, the WTSA MMFI and Manchester Fungal Infection Group (MFIG) took the Killer Fungus exhibit to the Manchester Science Festival as a Platform for Investigation (Pi) in the Museum of Science and Industry.

Many elements of the original Killer Fungus exhibit remained, including the Fungal Invaders and Evolution computer games, videos of a giant petri dish growing fungi and researchers' stories, a human manikin to demonstrate sites of fungal infection and clay modelling stations where incredible models of fungi were made.

This Killer Fungus event also had an exciting new addition: Outbreak! This app-based, role-playing game simulated a fungal disease outbreak, where teams were able to collect clues and QR codes to find the cause. People had to sign up for the game on the day and it was so popular, it sold out within two hours (49 adults and 58 children participated). Over 1200 visitors (655 adults, 635 children) attended the whole event, which was a resounding success.
Year(s) Of Engagement Activity 2017
URL http://www.killerfungus.org/games/
 
Description Max Perutz Writing Prize 2017 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Maria Spyrou, a PhD student from the MRC CMM /Aberdeen Fungal group is one of 14 shortlisted for the award for her essay titled "Orchestration of chitin synthesis: Could understanding this process be a deadly fungus kryptonite?" Fernanda Alonso, WTSA MMFI PhD student also submitted an article for the deadline 4th July 2017. Maria attended the awards ceremony on 19th October 2017 and had her essay published on MRC Insight Blog page. The University if Aberdeen also published a news story about Maria and her essay and re-published her essay (https://www.abdn.ac.uk/news/11238/).
Year(s) Of Engagement Activity 2017
URL https://www.abdn.ac.uk/news/11238/
 
Description May Festival at University of Aberdeen 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Dr Janet Willment along with PhD students and Postdocs from MRC CMM manned an exhibition stand at the May Festival titled "Fighting Fungal infection. Children and adults had the opportunity to participate in interactive activities e.g. view fixed fungi under microscopes, build their own fungus etc. and interact with MRC CMM researchers to find out mre about heir research.
Year(s) Of Engagement Activity 2017
 
Description National and International Conferences 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The principal investigators, early career fellows, postdoctoral researchers and students working in MRC CMM participate in a number of national and international conferences and meeting through the year - as Keynote speakers, invited speakers, student talks and posters. Some of the major meeting are listed here: (1) British Society for Medical Mycology (BSMM, annual meeting), Microbiology Society Annual Conference and Irish Branch Conference, British Mycology Society Annual meeting, Fungal Genetics Conference in Asilomar, Gordon Research Conferences (Immunology of Fungal Infections in Jan 2017 and Molecular and Cellular Fungal Biology in June 2016), American Society for Microbiology (ASM) Microbe, International Society for Human and Animal Mycology Congress (ISHAM, triennial), British Society of Immunology Annual meeting (BSI), Keystone Immunology series (biennial), FEBS Human Fungal Pathogens Conference etc.
Year(s) Of Engagement Activity 2016,2017
 
Description Nature front cover Aspergillus 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Gordon Brown and colleagues have secured the front cover picture of Nature's issue on 15th March Volume 555 Number 7696 pp285-402 Fighting Fungi to accompany his Nature paper published on 28th February 2018 - Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus
Year(s) Of Engagement Activity 2018
URL https://www.nature.com/nature/volumes/555/issues/7696
 
Description News Articles 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Media around the publication in Science by Professor Matt Fischer at Imperial College London, titled " Worldwide emergence of resistance to antifungal drugs challenges human health and food security". Professor Gordon Brown was quoted in news article by Independent new online "Deaths from fungal infections exceeding malaria, say researchers in new drug resistance warning" and BBC news online "Growing resistance to antifungal drugs 'a global issue"
Year(s) Of Engagement Activity 2018
URL http://www.bbc.co.uk/news/health-44160730
 
Description News article - AFGrica unit opening 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Times Science Live and Business Live - news articles to mark the opening of the AFGria unit in University of Cape Town on 11th August 2017, a joint initiative between UCT and the University of Aberdeen led by Professor Gordon Brown - http://www.timeslive.co.za/news/sci-tech/2017-08-11-uct-opens-first-global-research-centre-on-killer-fungi/ and https://www.businesslive.co.za/bd/world/africa/2017-08-11-uct-and-university-of-aberdeen-fight-fungal-infections-in-africa/
Year(s) Of Engagement Activity 2017
URL http://www.timeslive.co.za/news/sci-tech/2017-08-11-uct-opens-first-global-research-centre-on-killer...
 
Description News articles and press releases - Nature Microbiology paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact A press release to mark the publication of the paper in Nature Microbiology was jointly issued by the University of Aberdeen and MRC Press Offices. Other news articles that appeared around the same time about the published research are listed here: (1) The Hippocratic Post - Hide and see with Fungi, (2) The Scotsman - Fungi can hide from the immune system, (3) Express - Thrush breakthrough: Potentially deadly fungus plays 'hide-and-seek' from immune system, (4) Yahoo Lifestyle New Zealand - Cure for thrush on the horizon?, (5) Yahoo Lifestyle Australia - Cure for thrush on the horizon?.
Year(s) Of Engagement Activity 2016
 
Description Newspaper article - Candida auris story 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Carlisle News & Star - a follow up story on the Candida auris story and a quote from Prof Neil Gow - president of Microbiology Society and Prof at MRC CMM - http://www.newsandstar.co.uk/news/national/article/Drug-resistant-fungus-strain-infects-more-than-200-patients-at-UK-hospitals-1d752303-ff7a-4b05-83d6-e9a480cdf87c-ds
Year(s) Of Engagement Activity 2017
URL http://www.newsandstar.co.uk/news/national/article/Drug-resistant-fungus-strain-infects-more-than-20...
 
Description Newspaper article - Nature Publication on new discovery led by Professor Gordon Brown 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact (1) To mark the publication of the Nature paper (28 February 2018) from Professor Gordon Brown team and collaborators, the University of Aberdeen issued a press release " New insight into body's response to killer fungus" which is accompanied by a YouTube film of Professor Brown being interviewed about the research by Aaron Crawford a PhD student in Dr Duncan Wilson's lab in MRC CMM/AFG https://www.abdn.ac.uk/news/11640/ accompanied by a You Tube video with GDB talking about the work. (2) The Herald newspaper also covered a story about the seminal research published in the Nature paper "Aberdeen research raises hope of drug for deadly fungus which kills transplant patients - http://www.heraldscotland.com/news/16055664.Drug_hope_against_deadly_fungus_which_kills_transplant_patients/ (3) The MRC also published an article about the research published in Nature - published https://www.mrc.ac.uk/news/browse/new-insight-into-bodys-response-to-killer-fungus/
Year(s) Of Engagement Activity 2018
URL https://www.abdn.ac.uk/news/11640/
 
Description Opportunity North East Film about mycoBiologics 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Opportunity North East (ONE) filmed Dr Fiona Rudkin and Professor Carol Munro about their research and commercialisation of their platform of antibodies. Promotional film about young business set-up in North East of Scotland and the support given by ONE (https://twitter.com/OpportunityNE_1).
Year(s) Of Engagement Activity 2018
 
Description Our Future Scotland Film 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Scottish Futures Forum - James Blake a member of young RSE Academy visited the Centre to interview Neil Gow, Gordon Brown, Katja, Alessandra and Bhawna (all postdocs) and take lab shots of the postdocs. The film is been commissioned by the Scotland's Futures Forum for the Scottish Government and excerpts will be taken to make a factual 15 minute video showcasing a variety of visions about the future for Scotland in 2030 and beyond. This involves interviewing a range of interesting people on camera and filming some good visual innovation projects and research work that may have a future impact on society.
The film was showcased at the Scottish Parliament on the 16th May 2018.
Year(s) Of Engagement Activity 2018
URL http://www.scotlandfutureforum.org/scotland-2030-programme/our-future-scotland/
 
Description Parliamentary and Scientific Committee on the topic of Human Fungal Diseases 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Professor Carol Munro was invited to join Dr Paul Richards, Policy Manager at Microbiology Society and Drs Rebecca Hall and Liz Ballou from University of Birmingham at the committee meeting on 17th July 2017. The group were representing the Microbiology Society at a meeting of the Parliamentary and Scientific Committee on the topic of Human Fungal Diseases. The meeting was followed by a reception and meal with the speakers and Chair.
Year(s) Of Engagement Activity 2017
 
Description Pecha Kucha presentation and featured in MRC Life magazine in April/May 2017 edition 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Dr Judith Bain gave a Pecha Kucha presentation as part of the British Science Week in a session called Scintillating Science on 16/03/2017. The event was featureed in MRC Life magazine in April/May 2017 edition.
Year(s) Of Engagement Activity 2017
 
Description PechaKucha: Scintillating Science - British Science Week 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Dr Jude Bain, a research fellow in the MRC CMM will give a PechaKucha presentation on her research at the Belmont Filmhouse in Aberdeen City on 16th March 2017. The PechaKucha evening is organised as a series of event to mark British Science Week (10-16th March 2017).
Year(s) Of Engagement Activity 2017
URL http://www.abdn.ac.uk/engage/nsew/#thurs16
 
Description Podcast - Nature Microbiology paper 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact To mark the official publication of the MRC CMM peer reviewed paper "Lactate signalling regulates fungal ß-glucan masking and immune evasion" in Nature Microbiology, the main authors Dr Elizabeth Ballou and Professor Alistair Brown gave a Podcast interview about the research.
Year(s) Of Engagement Activity 2016
URL https://soundcloud.com/mrccmm
 
Description Poscast - MBio paper 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Neil Gow and Dr Jeannette Wagener join host Aaron Crawford to discuss their latest paper published in MBio, "Candida albicans chitin increases arginase-1 activity in human macrophages with impact on macrophage antimicrobial functions".
Year(s) Of Engagement Activity 2017
URL https://soundcloud.com/mrccmm
 
Description Presentation - Science After Dark 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Science After Dark at Aberdeen Science Centre - A newly named "Science After Dark" programme was launched on Friday 18th May 2018 at the Aberdeen Science Centre and was themed around space. This event was part of a programme series which educates and entertain an adult lay audience. MRC CMM's Dr. Katja Schaefer (Post doc) was talking about "Alien -microbiology and the Infection risk of human mission to space"
Year(s) Of Engagement Activity 2018
 
Description Presentation at May Festival in Aberdeen 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Dr Fiona Rudkin, CEO of mycoBiologics (spin out from MRC CMM) gave a presentation on developing her platform of monoclonal antibody based therapeutics for treating fungal infections.
Year(s) Of Engagement Activity 2018
 
Description President's Award Lecture, British Mycological Society, Exeter, UK Society symposium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Neil Gow was invited to give the BMS President's Awards Lecture at the BMS symposium in September 2016
Year(s) Of Engagement Activity 2016
 
Description Press Releases - Afgrica unit - Lecturer appointment 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Tackling Fungal Infections: First staff appointed to Cape Town AFGrica Unit - Press release from UoA and UCT regarding the AFGrica unit appointment of staff. Quote given by Professor Gordon Brown, Director of MRC CMM and lead for AFgrica unit. The Evening Express in Aberdeen also covered the story - "First Staff appointed to fungal research unit run by university"
Year(s) Of Engagement Activity 2018
URL https://www.abdn.ac.uk/news/12091
 
Description Press release - Dr Fiona Rudkin publication in Nature Communications 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Press release by University of Aberdeen and Exeter "Human antibody discovery could save lives from fungal killer " to coincide with the publication of Dr Fiona Rudkin's paper in Nature Communications - "Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis". The article was picked-up by social media and other online media such as ScienceDaily - https://www.sciencedaily.com/releases/2018/12/181211073247.htm
Year(s) Of Engagement Activity 2018
URL https://www.abdn.ac.uk/news/12543/
 
Description Promotional material for donors and supporters 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Supporters
Results and Impact Through the University of Aberdeen Development Trust we are aiming to attract charitable donations to support our research. Fungal Research is one of the key areas promoted by the Trust - see the dedicated online link on the Development Trust website in URL below. We have also designed a promotional leaflet suitable for a donor audience which is distributed at events such as Doors Open.
Year(s) Of Engagement Activity 2016
URL http://www.abdn.ac.uk/giving/aberdeen-fungal-group-425.php
 
Description Radio interviews - various 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact (1) 19th August 2017 - BBC Wiltshire radio interview by Amy Griffiths | Broadcast Journalist who does the Drive Show - interviewed Professor Neil Gow on the Candida auris story following the newspaper articles on the Japanese fungus/C.auris and NHS publication of results of infection of C.auris and guidelines for hospitals. (2) 19th September 2017 - Professors Gordon Brown and Neil Gow were interviewed by SHMU Radio Aberdeen to promote their Café Scientifique talk "Battling the Killer Fungus" at Waterstone's Bookstore in Aberdeen on 20th September 2017 (https://www.abdn.ac.uk/cmm/public-engagement/media.php) and (3) Professor Gordon Brown was interviewed by Ken Gibson for BBC Radio Scotland following the publication of the Nature paper "Recognition of DHN-melanin by the novel C-type lectin, MelLec, is essential for protective immunity to Aspergillus fumigatus" from his research group on 28th February 2018.
Year(s) Of Engagement Activity 2017
 
Description Royal Society FRS Fellow talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Neil Gow was awarded a Fellow of The Royal Society in July 2016.
Year(s) Of Engagement Activity 2016
 
Description STEM for Britain 2018 - House of Commons 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Ingrida Raziunaite, a PhD student in the MRC CMM/Aberdeen Fungal Group has been chosen as one of 30 students from 600 applications to present a poster at the House of Commons at the "STEM for Britain 2018" event that will take place on Monday 12th March 2018 in the Biological and Biomedical Sciences Session. University of Aberdeen will issue a an internal Staff piece after the event. Ingrida has been invited to write a blog of her experience at the STEM event for the MRC Insight Blog which will be published shortly after the event on 12th March.
Year(s) Of Engagement Activity 2017
 
Description Sanger Centre and LMB visit 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Gordon Brown, was invited to present at the XXXXX at the Sanger Centre xxxx
Year(s) Of Engagement Activity 2016
 
Description School Visit - Gilcomstoun Primary School 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Helen Heaney, a PhD student in Professor Alistair Brown's lab attended two 2 assembly sessions at Gilcomstoun Primary School in Aberdeen City in May 2018. The age groups involved were, P1-P3 and P4-P7. Helen spoke to them about being a scientist and a PhD student and used soft toy Giant Microbes to introduce the younger children to fungi and the older ones to her research project.
Year(s) Of Engagement Activity 2018
 
Description School visit (Aberdeen City) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Dr Delyth Reid, Research Fellow from the MRC CMM was invited to participate and host a stand on Careers Day at Robert Gordon College, Aberdeen City on 2nd November 2016. In addition to explaining to the secondary school children what a career as a microbiologist and academic researcher involves, Dr Reid also introduced, with the use of interactive activities, the nature of medical mycology and fungal immunology research and its importance in public health.
Year(s) Of Engagement Activity 2016
 
Description Schools invite 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact Professor Neil Gow, Deputy Director for Research in MRC CMM was invited to do a School's lecture to senior level pupils (year 11-13, age 16-18) at St John's School, Leatherhead, Surrey, UK. in February 2017.
Year(s) Of Engagement Activity 2017
 
Description Scientist in Residence - School in Aberdeen City 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Dr Donna MacCallum, a principal investigator in the MRC CMM was the co-applicant and Scientist in Residence on a successful Royal Society Partnership award with Ms Amanda Kirk at Gilcomstoun Primary School. The award allowed a science club to be set up (purchase of science equipment and consumables) and a project carried out to evaluate the effectiveness of household cleaners on fungi.
Year(s) Of Engagement Activity 2016
 
Description Seminar University of Cardiff 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Gordon Brown was invited to present on 8th November at a seminar at the University of Cardiff
Year(s) Of Engagement Activity 2016
 
Description Soapbox Science - May Festival 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact As part of the University of Aberdeen's May Festival 25-27th May 2019, Dr Delma Childers (Postdoc) and Dr Donna MacCallum (Senior Lecturer) from MRC CMM participated in Soapbox Science in Aberdeen City - The full line up is available here: http://soapboxscience.org/soapbox-science-2018-aberdeen/. Donna spoke about "Fungal Foes - find out more!" and Delma (@bella_delma) spoke about "The Science and Scientists Behind the Movies" .
Year(s) Of Engagement Activity 2018
 
Description Symposium on diagnosis and treatment of fungal infections for paediatric patients 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Adilia Warris (MRC CMM) was invited to speak at the symposium on "Treatment of Fungal Infections". The symposium was held in Stockholm, Sweden with a national audience of mainly medical doctors.
Year(s) Of Engagement Activity 2016
 
Description TechFest 2017 - Tomorrow's Doctors: Medical Students Leading Cutting-Edge Research 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact On 20th September 2017, the Aberdeen Student Society for Academic Medicine, University of Aberdeen hosted an event for Aberdeen TechFest 2017 called "Tomorrow's Doctors: Medical Students Leading Cutting-Edge Research". Dominika Boldovjakova (an Aberdeen Summer Research Scholarship student & Year 2 Medical Student) presented her summer scholarship project and results in an oral presentation and poster called "New antifungal targets: bedside to bench". Dominika's supervisor for her summer project in the MRC Centre for Medical Mycology was Dr Deborah Lockhart, Wellcome Trust Clinical Postdoctoral Fellow. The event featured in the local newspaper Press & Journal
Link to article in the Press & Journal article Future doctors to present revolutionary findings at TechFest 2017
https://www.pressandjournal.co.uk/fp/news/aberdeen/1326273/exclusive-future-doctors-to-present-revolutionary-findings-at-techfest-2017/
Year(s) Of Engagement Activity 2017
URL https://www.pressandjournal.co.uk/fp/news/aberdeen/1326273/exclusive-future-doctors-to-present-revol...
 
Description The Conversation - Article 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Professor Gordon Brown, MRC CMM Director wrote an article for The Conversation UK titled "Five facts that show we know too little about fungi, and their harmful effects on human health"
Year(s) Of Engagement Activity 2018
URL https://theconversation.com/five-facts-that-show-we-know-too-little-about-fungi-and-their-harmful-ef...
 
Description Trends in Paediatric Mycology in Europe. 3rd Training Course for Paediatric Infectious Diseases Trainees 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Adilia Warris was invited to give a talk at the 3rd Training Course for Paediatric Infectious Diseases Trainees in Seville on "Modern Trends in Infectious Diseases and Immunology": Trends in Paediatric Mycology in Europe. The target audience was clinical trainees, fellows and consultants in paediatric infectious diseases.
Year(s) Of Engagement Activity 2016
 
Description UK Fungus Day 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact On the 9 October 2016. Aberdeen Science Centre hosted UK Fungus Day, an initiative that aims to raise awareness of fungi and fungal science. Visitors had the opportunity to meet our researchers at the "Kingdom of Fungi" Exhibition and learn about the big challenges we face in fighting fungal disease. We had activities for a range of different ages and got an amazing production of play- dough fungi! Aberdeen Science Centre organised a hands-on workshop dissecting and exploring the different parts of a mushroom and showing that fungi need the same nutrients as us to grow. Families also observed the production of carbon dioxide by yeast, which we use to make bread rise. The day ended with a talk by Prof Neil Gow (MRC CMM) and Prof. Ian Stansfield (Uni of Aberdeen) on "Fungi: good guys or rotters?" The audience were able to taste and smell different samples learning how fungi contribute to food and drink production.
Year(s) Of Engagement Activity 2016
URL http://www.abdn.ac.uk/cmm/public-engagement/public-events.php
 
Description University Lectures 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Undergraduate students
Results and Impact (1) Professor Gordon Brown gave a presentation on medical mycology and fungal immunology to undergraduate medical students at St Andrew's University in April 2017 and MSc students at the University of Oxford in February 2018. (2) Professor Gordon Brown gave a seminar and an introduction at the University of Liverpool to staff and students in The Wolfson Centre for Personalised Medicine (part of an overall visit to explore future collaborations) in February 2018.
Year(s) Of Engagement Activity 2017
 
Description VIRULENCE OF PHYTO- AND HUMAN-PATHOGENIC FUNGI 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Neil Gow was an invited Keynote speaker at this meeting which was held in the University Hospital's Microbiology Institute in Erlangen, Germany.
Year(s) Of Engagement Activity 2016
 
Description Visit to MRC CMM laboratories 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Hosted two high school (S6, 16+ years old) children on 4th and 5th October 2017 - 1 student from Mearns Academy, Montrose and 1 student Mackie Academy, Stonehaven. Both students had previously heard Professor Gordon Brown speak at a Café Scientific event and contacted him requesting work experience. The students shadowed designated research staff in the laboratories and were given some experimental work to do. The feedback from our research staff was that both students were very enthusiastic and were very grateful for the opportunity. The MRC CMM liaison contact with the schools, Dr Delyth Reid said " I predict they would make good scientists for several reasons".
Year(s) Of Engagement Activity 2017