MRC Centre for Reproductive Health at the University of Edinburgh
Lead Research Organisation:
University of Edinburgh
Department Name: MRC Centre for Reproductive Health
Abstract
Abnormalities associated with reproductive system and reproductive processes are common in modern society affecting both man and women. They result in major physical and psychological burden on many individuals. They also have huge impact on UK health system and economy. A few representative examples include: endometriosis which affects 1 in 10 women of reproductive age in the UK and cost the UK economy £8.2 billion a year in treatment, loss of work and healthcare costs; stillbirth - there are more than 3,600 stillbirths every year in the UK, and one in every 200 births ends in a stillbirth; and ovarian cancer that in UK alone kills nearly 12 women every day. Importantly, reproductive health problems are often linked to lifestyle factors such as smoking and obesity, but these links are not completely understood.
The Medical Research Council - Centre for Reproductive Health in Edinburgh (MRC-CRH) is the only UK-based reproductive health/biology centre that brings together basic scientists, diagnosticians and clinicians specialising in health, biology and pathology of reproductive system and reproductive processes at all levels: from genes and molecules to population based studies and lifestyle-disease links. The Centre is located in the world-renowned Queen's Medical Research Institute in the direct proximity of the Edinburgh Royal Infirmary (a teaching hospital for the University of Edinburgh Medical School run by NHS Lothian), a few other top class research institutions and a commercialisation incubator (Edinburgh BioQuarter). This optimises the use of resources, increases interdisciplinary collaborations and enhances commercialisation activities. Over the past five years the Centre grew significantly in both staff numbers and its research output and proved its value to society, for example, a single "STOPPIT" study on efficiency of progesterone treatment in preterm birth prevented 11,000 patients from painful ineffective treatment in the UK alone saving NHS £25M annually.
Within the next five years we intend to build on our past achievements to boost MRC-CRH research/education potential and infrastructure of the Centre. The main aims of this project are to (i) consolidate and reinforce MRC-CRH scientific activities, (ii) increase the Centre's educational role, and (iii) enhance interactions of the Centre's investigators and students with patients, medical practitioners and general public, rising awareness about reproductive health conditions and other topics related to our research. MRC funds will be used to (a) purchase specialised equipment that will increase research capability and open new frontiers for future investigations (micro-injection and oocyte handling, sophisticated interference and fluorescent microscopy), (b) recruit necessary expert personnel in imaging technology, database management/bioinformatics and scientific communication to sustain/expand our research capacity and outreach activities, (c) establish a top quality PhD programme in reproductive health/biology for clinical and non-clinical scientists.
It is our ambition through another five years of MRC funding to maintain and expand our world-class research into new areas including cancers of the reproductive tract, the effects of life-style (obesity, smoking etc.) on reproductive health and proliferative disorders of the reproductive system. It is our aim that our discoveries will impact the health and well-being of the Nation's population through their entire life-span. This improvement in health will have significant consequences for individuals, families and the society in general with noticeable economic benefits.
The Medical Research Council - Centre for Reproductive Health in Edinburgh (MRC-CRH) is the only UK-based reproductive health/biology centre that brings together basic scientists, diagnosticians and clinicians specialising in health, biology and pathology of reproductive system and reproductive processes at all levels: from genes and molecules to population based studies and lifestyle-disease links. The Centre is located in the world-renowned Queen's Medical Research Institute in the direct proximity of the Edinburgh Royal Infirmary (a teaching hospital for the University of Edinburgh Medical School run by NHS Lothian), a few other top class research institutions and a commercialisation incubator (Edinburgh BioQuarter). This optimises the use of resources, increases interdisciplinary collaborations and enhances commercialisation activities. Over the past five years the Centre grew significantly in both staff numbers and its research output and proved its value to society, for example, a single "STOPPIT" study on efficiency of progesterone treatment in preterm birth prevented 11,000 patients from painful ineffective treatment in the UK alone saving NHS £25M annually.
Within the next five years we intend to build on our past achievements to boost MRC-CRH research/education potential and infrastructure of the Centre. The main aims of this project are to (i) consolidate and reinforce MRC-CRH scientific activities, (ii) increase the Centre's educational role, and (iii) enhance interactions of the Centre's investigators and students with patients, medical practitioners and general public, rising awareness about reproductive health conditions and other topics related to our research. MRC funds will be used to (a) purchase specialised equipment that will increase research capability and open new frontiers for future investigations (micro-injection and oocyte handling, sophisticated interference and fluorescent microscopy), (b) recruit necessary expert personnel in imaging technology, database management/bioinformatics and scientific communication to sustain/expand our research capacity and outreach activities, (c) establish a top quality PhD programme in reproductive health/biology for clinical and non-clinical scientists.
It is our ambition through another five years of MRC funding to maintain and expand our world-class research into new areas including cancers of the reproductive tract, the effects of life-style (obesity, smoking etc.) on reproductive health and proliferative disorders of the reproductive system. It is our aim that our discoveries will impact the health and well-being of the Nation's population through their entire life-span. This improvement in health will have significant consequences for individuals, families and the society in general with noticeable economic benefits.
Technical Summary
The MRC-CRH will integrate its proven strengths in reproductive health and biology (training, multilevel basic/clinical research, clinical trials and implementation of new treatments/procedures) around four scientific themes linking basic and clinical researchers to enhance translational output: (1) Reproductive resilience, proliferation, differentiation and repair; (2) Reproductive system cancers: aetiology, pathogenesis and therapy; (3) Optimizing life-long health through pregnancy and perinatal interventions; (4) Immune-endocrine interactions in reproductive health. These will be reinforced by a dedicated interdisciplinary reproductive health/biology PhD training programme (3-4 years) for both clinical and non-clinical scientists. The programme will produce and sustain a generation of new academic/clinical reproductive health/biology experts increasing UK research capacity in this important field. Emphasis will be put on extending our current research infrastructure by implementing state-of-the-art technologies in micro-injection and oocyte handling and increasing our capabilities for in situ quantitative monitoring of biological processes using real-time intravital fluorescent and interference microscopy. This will be associated with recruitment of imaging specialist and database manager to maintain the systems, provide training and facilitate image processing, analysis and bioinformatics. We intend to enhance our general public training/education activities and online presence which will be facilitated by recruitment of a dedicated scientific communications manager.
Planned Impact
Diverse aspects of reproductive biology/health influence the society at multiple levels (health/wellbeing, lifestyle, culture, economy etc.) and are essential for survival of mankind. Basic, translational and clinical research performed at the MRC-CRH impacts a number of people, organisations and sectors in the population at local, national and global scale. Main non-academic beneficiaries of our activities include:
(a) Policymakers, public health educators and general population. Our research and clinical trials continuously provide data that directly informs many guidelines for treatment and lifestyle advice for the population. This is facilitated by MRC-CRH members siting in various advisory bodies linked to organisations playing leading roles in policy development nationally and internationally (e.g. The National Institute for Health and Care Excellence; World Health Organisation). Usually it takes at least a few years (2-5) to convey MRC-CRH generated clinical data into active public policies but we have also examples of much faster impact (e.g. results of "Outcomes of elective induction of labour compared to expectant management: a population based study" translated into international policy changes in less than 2 years from original publication (Stock et al. BMJ. 2012;344:e2838)). Our studies will inform the health of all of society, for example investigations on the effects of obesity, smoking and stress on pregnancy will lead to lifestyle advice to the population. Similarly studies in contraception (particularly male contraceptives), if successful, may lead to alteration in behaviour.
(b) Patients, their relatives and friends. Patients benefit from our research directly through ability to use new therapeutic approaches (e.g. MRC-CRH Anderson co-developed new procedures and protocols for freezing of ovarian tissue to allow women to have children after cancer therapy), possibility to get exposed to novel (potentially life-changing) therapies at clinical trial stage and patient-directed educational activities, and indirectly through improved health policies and practices that we impact. Pregnancy and healthy birth are not only life-changing events for a woman but they usually also have enormous impact on her family and friends. Routine induction of labour at 39 weeks for all women stemming from our research is calculated to prevent the perinatal death of 500 babies per year and we will continue our efforts to further improve this figure.
(c) NHS and health system. Our research influences NHS standards and operating procedures, it also leads to identification of improved or ineffective treatments and significant savings/ better allocation of resources in the health system (e.g. STOPPIT study led by Norman showed that progesterone was ineffective in women with tween pregnancy and has prevented ineffective treatment of 11,000 women annually with huge savings for NHS). Our research often targets conditions that increase morbidity without being life-threatening (e.g. endometriosis, fibroids and heavy menstrual bleeding), these conditions are associated with enormous strain on the health system and big economic costs through loss of work.
(d) Medical practitioners. These people benefit from our contributions to general medical knowledge (e.g. Pollard's research has been described in textbooks such as "Molecular Biology of the Cell" and "Pathophysiology" where his work is featured on the front cover.), regular training opportunities and increased patient/general public awareness about reproductive system health and diseases promoted by MRC-CRH.
(e) Economy and commerce. Our spinout company Ichthus Therapeutics is developing novel products focused on women's health (in particular endometriosis and endometriosis-associated pelvic pain). Within the next 5 years we plan to spin out additional companies and facilitate increase in job opportunities and capital gain generated by them with direct benefit for local economy.
(a) Policymakers, public health educators and general population. Our research and clinical trials continuously provide data that directly informs many guidelines for treatment and lifestyle advice for the population. This is facilitated by MRC-CRH members siting in various advisory bodies linked to organisations playing leading roles in policy development nationally and internationally (e.g. The National Institute for Health and Care Excellence; World Health Organisation). Usually it takes at least a few years (2-5) to convey MRC-CRH generated clinical data into active public policies but we have also examples of much faster impact (e.g. results of "Outcomes of elective induction of labour compared to expectant management: a population based study" translated into international policy changes in less than 2 years from original publication (Stock et al. BMJ. 2012;344:e2838)). Our studies will inform the health of all of society, for example investigations on the effects of obesity, smoking and stress on pregnancy will lead to lifestyle advice to the population. Similarly studies in contraception (particularly male contraceptives), if successful, may lead to alteration in behaviour.
(b) Patients, their relatives and friends. Patients benefit from our research directly through ability to use new therapeutic approaches (e.g. MRC-CRH Anderson co-developed new procedures and protocols for freezing of ovarian tissue to allow women to have children after cancer therapy), possibility to get exposed to novel (potentially life-changing) therapies at clinical trial stage and patient-directed educational activities, and indirectly through improved health policies and practices that we impact. Pregnancy and healthy birth are not only life-changing events for a woman but they usually also have enormous impact on her family and friends. Routine induction of labour at 39 weeks for all women stemming from our research is calculated to prevent the perinatal death of 500 babies per year and we will continue our efforts to further improve this figure.
(c) NHS and health system. Our research influences NHS standards and operating procedures, it also leads to identification of improved or ineffective treatments and significant savings/ better allocation of resources in the health system (e.g. STOPPIT study led by Norman showed that progesterone was ineffective in women with tween pregnancy and has prevented ineffective treatment of 11,000 women annually with huge savings for NHS). Our research often targets conditions that increase morbidity without being life-threatening (e.g. endometriosis, fibroids and heavy menstrual bleeding), these conditions are associated with enormous strain on the health system and big economic costs through loss of work.
(d) Medical practitioners. These people benefit from our contributions to general medical knowledge (e.g. Pollard's research has been described in textbooks such as "Molecular Biology of the Cell" and "Pathophysiology" where his work is featured on the front cover.), regular training opportunities and increased patient/general public awareness about reproductive system health and diseases promoted by MRC-CRH.
(e) Economy and commerce. Our spinout company Ichthus Therapeutics is developing novel products focused on women's health (in particular endometriosis and endometriosis-associated pelvic pain). Within the next 5 years we plan to spin out additional companies and facilitate increase in job opportunities and capital gain generated by them with direct benefit for local economy.
Organisations
People |
ORCID iD |
| Jeffrey Pollard (Principal Investigator) |
Publications
Abokhrais IM
(2018)
A pilot randomised double blind controlled trial of the efficacy of purified fatty acids for the treatment of women with endometriosis-associated pain (PurFECT): study protocol.
in Pilot and feasibility studies
Adibi JJ
(2021)
First trimester mechanisms of gestational sac placental and foetal teratogenicity: a framework for birth cohort studies.
in Human reproduction update
Ahmad SF
(2020)
Targeting colony stimulating factor-1 receptor signalling to treat ectopic pregnancy.
in Scientific reports
Ahmad SF
(2018)
Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin ß1 to Promote Embryo-tubal Attachment.
in EBioMedicine
Al-Hendy A
(2021)
Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy.
in The New England journal of medicine
Al-Memar M
(2018)
The potential value of activin B and fibronectin for the triage of pregnancies of unknown location and prediction of first trimester viability.
in Australasian journal of ultrasound in medicine
Alberico H
(2022)
Workflow Optimization for Identification of Female Germline or Oogonial Stem Cells in Human Ovarian Cortex Using Single-Cell RNA Sequence Analysis.
in Stem cells (Dayton, Ohio)
Aldhous MC
(2019)
HPV infection and pre-term birth: a data-linkage study using Scottish Health Data.
in Wellcome open research
| Title | IPS derived human macrophages |
| Description | We have generated new method to prepare and genetically modify Induced pleuripotent stem cell derived human macrophages. To propagate this technology to others we have published detailed methods in "Methods in Enzymology" . To further disseminate our skills to the scientific community, we also published "Jove" video papers describing the methodology for iPS derived macrophage (in Press). |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| Impact | This method enables study of human macrophages that was previously impossible. It will imapact greatly research in cancer and tissue repair. |
| Title | Tumor associated macrophage and monocyte transcriptomes |
| Description | We generated a large amount of sequencing data for monocytes and macrophages in human breast and endometrial cancer that can be searched by others. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | Data is available in the URL below and at GSE 10095 and 117970 These data sets are unique and might be used for diagnostic, prognostic and discovery studies |
| Description | "Oestrogens - the good, the bad, and the unexpected" talk at the Society for Endocrinology annual meeting, Glasgow |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Evan Simpson gave a symposium talk at the Society for Endocrinology annual meeting in Glasgow in November entitled "Oestrogens - the good, the bad, and the unexpected". |
| Year(s) Of Engagement Activity | 2018 |
| Description | '31st Annual Critical Issues in Tumor Microenvironment Course : from Bench to Bedside to Bomarkers' Harvard, Boston |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speaker/Assessor : Angiogenesis, Metastasis and Immunology |
| Year(s) Of Engagement Activity | 2016 |
| Description | 'It gives you hope': the fight to save the fertility of children with cancer, Interview with The Guardian, United Kingdom |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof. Richard Anderson and Dr. Rod Mitchell were involved in an interview by the Guardian, to talk about how their technology and medical procedures could prevent infertility in babies, children and teenagers with cancer treatment. |
| Year(s) Of Engagement Activity | 2018 |
| Description | 'Licensing the Immune System in Health & Disease' University of Basel, Switzerland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speaker, 5th Basel Immunology Focus Symposium (BIFS) |
| Year(s) Of Engagement Activity | 2017 |
| Description | 'Regulatory Myeloid Cells: From Basic Discovery to Therapeutic Application' Conference, The Wistar Institute, Philadelphia, US. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This conference focused on the pathological functions of myeloid-derived suppressor cells, dendritic cells, macrophages and neutrophils, and provided a forum for in-depth discussion of the most pressing issues associated with the biology and clinical application of these cells. The conference brought together scientists from academia and industry interested in the basic and translational aspects of these cells in pathological conditions, especially cancer. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://sitc.sitcancer.org/sitc-meetings/collaborative/wistar2016 |
| Description | 'The Fertility Podcast'. Andrew talked about the importance of raising awareness of endometriosis - Andrew Horne |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Andrew Horne featured in a new episode of 'The Fertility Podcast'. Andrew talked about the importance of raising awareness of endometriosis including his ground-breaking new trial at CRH, and how it is paving the way for new treatments. A case study also gave her own personal experience of living with endometriosis. Andrew Horne spoke about endometriosis, including treatment options and research findings, followed by a useful Q&A at a joint virtual meeting of EndoFife and EndoDundee patient groups on 22 June 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | 'The Year My Vagina Tried to Kill Me' post-dicussion, Manchester |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Andrew Horne teamed up with comedian Amy Vreeke to answer audience questions about endometriosis. The event was held in Manchester and was recorded as an engaging an informative event which broached serious subjects couched in comedy. |
| Year(s) Of Engagement Activity | 2019 |
| Description | 'Understanding Tumor Immunology' - Speaker |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Beatson Institute for Cancer Research workshop on Tumor Immunology, Glasgow UK |
| Year(s) Of Engagement Activity | 2017 |
| Description | 'Voices and Visions' endometriosis podcast with Andrew Horne |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | The new 'Voices and Visions' podcast has been created by the World Endometriosis Society (WES). This series aims to uncover the views, journeys, and experiences of both researchers and patients. In the inaugural episode the hosts - CRH's Francesca Hearn-Yeates (PhD student, Horne lab group) interviews Andrew. He talks about his career trajectory, the importance of endometriosis research, his clinical trials at CRH, and what he does to relax when he is not undertaking vital clinical care or research to improve the lives of those affected by this painful condition. |
| Year(s) Of Engagement Activity | 2022 |
| Description | 'WHO IS WHO' meeting of the Mye-Infobank - Jeff Pollard and Florent Petitprez |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Jeff Pollard and Florent Petitprez attended the 'WHO IS WHO' meeting of the Mye-Infobank on 27.10.21. Jeff and Florent are the UK representative for the COST Mye-infobank trans European network for myeloid cell bioinformatics. Myeloid immune cells are important mediators in the pathology of many diseases, especially in diseases associated with chronic inflammation (DACI). Recent advancements in molecular profiling technologies have led to the generation of large data sets, many of those not fully explored yet, but accessible to the entire scientific community via public data repositories. It is the aim of this COST Action to repurpose those data sets, retrieve and curate myeloid cell-specific information, and apply this information to develop novel biomarkers for DACI. To this end, Mye-InfoBank utilises COST networking tools to enable the interaction of molecular biologists, bioinformaticians, immunobiologists, biobank coordinators and clinicians. The concerted activity of these experts on myeloid cell biology (either basic or clinical research) MYE, bioinformatics INFO, and bio-banking BANK, transforms complex molecular information into standardised and applicable biomarkers, which have the potential to improve clinical decision making in a number of socio-economically important diseases. |
| Year(s) Of Engagement Activity | 2021 |
| Description | 100 years of Phagocytes, Mario Teti Foundation, Messina: Cell Symposium, Sicily, Italy |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Bringing together cell biologists, immunologists, and developmental biologists interested in exploring phagocytes' diverse roles in tissue biology, identifying gaps in our current knowledge and defining disease pathways. |
| Year(s) Of Engagement Activity | 2016 |
| Description | 10th workshop of the European Network of Breast Development and Cancer labs (ENBDC); Weggis, Switzerland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Macrophage maleficence in cancer |
| Year(s) Of Engagement Activity | 2018 |
| Description | 14th conference of FIAPAC in Riga |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sharon Cameron , Michelle Cooper and John Reynolds Wright participated at the 14th conference of FIAPAC in Riga (8-10 OctOBER) whose theme was 'Fertility control in the hands of women'. Sharon Cameron is current President of FIAPAC . Sharon and Michelle gave plenary lectures and John Reynolds-Wright was awarded a grant from Exelgyn- FIAPAC for a pilot RCT of different analgesia to manage pain associated with medical abortion. |
| Year(s) Of Engagement Activity | 2022 |
| Description | 16th Congress of the European Society of Contraception and Reproductive Health in Ghent Belgium, |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sharon Cameron attended the 16th Congress of the European Society of Contraception and Reproductive Health in Ghent Belgium, following the theme: "Challenging times, are we ready? Novel approaches to sexual and reproductive health". She co-ordinated Block 1: The many faces of birth control with new views on contraception and abortion (25.5.22). |
| Year(s) Of Engagement Activity | 2022 |
| Description | 1st National Symposium on Immunology and Immunotherapy of Cancer. Amsterdam, Netherlands |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tumor Associated Macrophages: From mechanism of action to therapy |
| Year(s) Of Engagement Activity | 2016 |
| Description | 2017 Early Detection of Cancer Conference - Speaker |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Annual Conference of Cancer Research UK and OHSU Knight Cancer Institute 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | 34th International Papillomavirus Conference - HPV Group |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Kate Cuschieri (Director of the Scottish HPV Reference Laboratory), Hana Elasifer (Co-ordinator of the Scottish HPV Archive) and Daniel Guerendiain (Associated Clinical Scientist and PhD student) will be presenting at the 34th International Papillomavirus Conference this November. Topics will include HPV testing for the risk stratification of anal disease, impact of HPV immunisation in Scotland, and the use of circulating tumour DNA for the monitoring and management of HPV associated disease. Kate Cuschieri will be joining a mentorship session for early career researchers looking to progress their career in HPV research. Kate Cuschieri will also give a plenary talk at the 2021 European Congress of Cytology in Wroclaw, Poland, entitled "HPV Primary Screening Pathways; negotiating the international landscape". The conference represents a hybrid of online and in person meeting: |
| Year(s) Of Engagement Activity | 2021 |
| Description | 34th International Papillomavirus Conference - IPVC, 15-19 November, 2021) - Hana Elasifer |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Hana Elasifer, of the HPV research group, presented her abstract on 'a systematic review of circulating HPV DNA for the monitoring of anogenital HPV associated disease' at the recent International Papillomavurs Meeting (34th International Papillomavirus Conference - IPVC, 15-19 November, 2021). Hana will be presenting her key findings at the next SHINe meeting. |
| Year(s) Of Engagement Activity | 2021 |
| Description | 37th Annual ESHRE Meeting (26 June to 1 July 2021). - Andrew Horne |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Andrew gave an invited lecture ("Patient reported outcome measures in clinical trials for pelvic pain") at the 37th Annual ESHRE Meeting (26 June to 1 July 2021). |
| Year(s) Of Engagement Activity | 2021 |
| Description | 37th Annual ESHRE Meeting (26 June to 1 July 2021). - Andrew Horne |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Andrew Horne Session title: Pain in endometriosis and adenomyosis - part 1 Session type: Precongress course - Patient reported outcomes in clinical trials for pelvic pain Session title: The endometrium in the 21st century Session type: Invited session |
| Year(s) Of Engagement Activity | 2021 |
| Description | 9th CCBIO Annual Symposium 2021 Bergen - Norway - Jeff Pollard |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | May 2021 Speaker, 9th CCBIO Annual Symposium 2021 Bergen - Norway |
| Year(s) Of Engagement Activity | 2021 |
| Description | A long-term study into the causes of premature birth has been launched by Sarah Brown, wife of former prime minister Gordon Brown. |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The Theirworld Edinburgh Birth Cohort will track the development of 400 babies, mostly born before 32 weeks, following them through to adulthood. The research at the University of Edinburgh MRC Centre for Reproductive Health is being funded with a £1.5m grant from the global children's charity Theirworld, of which Ms Brown is founder and president. |
| Year(s) Of Engagement Activity | 2016 |
| Description | AACR 107th Annual Meeting 2016, New Orleans |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speaker : CIMM/TME Joint Scientific Session |
| Year(s) Of Engagement Activity | 2016 |
| Description | AACR Seattle US |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Delivering Cures Through Cancer Scienc |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://ecancer.org/conference/calendar/786-aacr-2016.php |
| Description | American Society for Cell Biology (ASCB) 'Cell Biology of Cancer' First Bookstop Symposium, San Francisco |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speaker : Macrophages Are a Cellular Toolbox That Promotes Tumor Progression and Metastasis |
| Year(s) Of Engagement Activity | 2016 |
| Description | Andrew Horne contributed expert commentary to this insightful article in The Times (published 13.10.22 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Endometriosis article and Live Q&A in The Times Andrew Horne contributed expert commentary to this insightful article in The Times (published 13.10.22). Up to 1.5 million women in the UK have endometriosis and this news piece outlines some of the challenges patients face in receiving a diagnosis and effective treatment. Following the publication of this piece, a live Q&A took place via The Times online and members of the public were invited to ask Andrew questions about endometriosis and his vital research. Jackie Maybin |
| Year(s) Of Engagement Activity | 2022 |
| Description | BACR special conference : 'The tumour microenvironment - basic science to novel therapies', University of Nottingham, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The conference covered a wide number of topics with sessions on tumour angiogenesis, hypoxia and metabolism, stroma, cancer and the immune system and the interstitial-stem cell niche. The focus of the conference was to give a broad overview of the tumour microenvironment by discussing important topics such as those described above. |
| Year(s) Of Engagement Activity | 2017 |
| Description | BBC Breakfast, United Kingdom |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Andrew Horne was interviewed by BBC Breakfast journalist Emma Barnett. |
| Year(s) Of Engagement Activity | 2019 |
| Description | BBC News Interview |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Jeffrey Pollard gave an interview to the BBC broadcasted live on Friday 4th March 2016. In this interview Prof Pollard commented on Nicholas Mc Granahan, Andrew Furness and Rachel Rosenthal's recent paper "Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade" published in Science. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.bbc.co.uk/news/health-35718491 |
| Description | BBC Radio Scotland - endometriosis |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Lucy Whitaker spoke to BBC Radio Scotland's Rona Dougall on 27.07.22 to raise awareness of endometriosis. |
| Year(s) Of Engagement Activity | 2022 |
| Description | BBC Radio Sheffield & BBC Woman's Hour - Feeding your Baby Poll, United Kingdom |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Erin Williams was on BBC Sheffield to discuss the results of a survey about how women feed their babies and how it makes them feel. |
| Year(s) Of Engagement Activity | 2019 |
| Description | BBC Scotland 'The Nine', Edinburgh |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Andrew Horne was interviewed by BBC Scotland to talk about Edinburgh's EXPPECT Centre for Pelvic Pain and Endometriosis. |
| Year(s) Of Engagement Activity | 2019 |
| Description | BBC Scotland news show 'The Nine' (12.05.22) to talk about the importance and future of telemedicine abortion. |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | CRH associate Sharon Cameron appeared on the BBC Scotland news show 'The Nine' (12.05.22) to talk about the importance and future of telemedicine abortion. This was following the news that women in Scotland will continue to be able to access an early medical abortion at home, a health service that medical evidence shows is safe, effective and preferred by women. |
| Year(s) Of Engagement Activity | 2022 |
| Description | BBC Stories, London |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Andrew Horne was interview by the 'bbcstories' short film in London. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Bid to ease burden of heavy periods steps up with new drug trial |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Women who suffer heavy periods are being invited to join a research study to test a new treatment for their condition. The trial will find out if boosting levels of a hormone produced in the lining of the womb can reduce blood loss during menstruation and ease women's symptoms. Researchers believe that a hormone - called cortisol - helps the small blood vessels in the womb lining to function well. If cortisol levels are too low in the womb, it can increase blood loss, researchers say. This study will test whether a drug that mimics the actions of cortisol - called dexamethasone - will boost the hormone to typical levels and reduce menstrual blood loss. The research aims to identify whether a short course of the drug, at a low dose, could also be used to manage heavy periods. Women who join the study will be asked to monitor their periods for two months. They will then be randomly assigned to receive either a short course of dexamethasone or a placebo pill for five days before their period is due, for the following three months. As is usual in clinical trials, neither the doctors nor the participants will know which medication they receive. Professor Hilary Critchley of the University of Edinburgh's MRC Centre for Reproductive Health, who is leading the trial, said: "Women who experience heavy bleeding during their period will often struggle with very challenging symptoms that impact their daily life. "Many of the current treatment options such as the contraceptive pill or hysterectomy affect a woman's fertility, and so we are keen to develop treatments that offer women a greater choice. Now we need more participants - to complete this vital research". |
| Year(s) Of Engagement Activity | 2016 |
| Description | Brain and Spine Institute, Paris |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Veronica Miron gave a talk at the Brain and Spine Institute in Paris, a world renowned institute for glial biology. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Brainwaves, BBC Radio 4 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Hilary Critchley was featured on the BBC Radio 4 popular series 'Brainwaves' to discuss about the importance of communicating about menstrual health. |
| Year(s) Of Engagement Activity | 2019 |
| Description | British Society for Colposcopy and Cervical Pathology meeting in Belfast |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Kate Cuschieri was invited to speak at the British Society for Colposcopy and Cervical Pathology meeting in Belfast in May. The in-person meeting benefits from attendance of a multidisciplinary group of gynaecologists, pathologists, nurse practitioner(s), patient representatives and advocates, charity personnel and more. Kate spoke about the implications of HPV vaccine for future cervical screening practice given the significantly reduced prevalence of high-risk HPV in Scotland. |
| Year(s) Of Engagement Activity | 2022 |
| Description | CRH researchers contribute to acclaimed BBC Sounds series |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | acclaimed BBC Sounds series A brilliant new series has been created for BBC Sounds called 28(ish) Days Later which focuses on the menstrual cycle. The series tracks what is happening in the body during menstruation as well as investigating important related stories including key research developments, social history, and the debunking of some persistent period myths. The aim of the series is that by marrying science with personal experiences listeners will begin to understand their bodies and behaviours like never before. It hopes to educate and raise awareness of menstrual health. MRC CRH's Jackie Maybin and Andrew Horne were selected to take part in this series and will appear in the following episodes, which focus on menstruation and endometriosis. Jackie Maybin's episodes (menstruation): • Episode 1: Power • Episode 2: The Flood • Episode 7: Oestrogen Rising • Episode 14: Ovulation • Episode 16: Oh Progesterone • Episode 24: To Bleed or Not To Bleed Andrew Horne episode (endometriosis): • Episode 3: Pain & Prejudice CRH Associate Evelyn Telfer contributed to episode 14: 'Ovulation'. |
| Year(s) Of Engagement Activity | 2022 |
| Description | CRH takes part in Midlothian Schools STEMFEST |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | CRH takes part in Midlothian Schools STEMFEST CRH researchers visited Beeslack High School as part of the October STEMFEST Festival, which took place across schools in Midlothian. Our 'Ready Steady Grow' scientific workshop was run with 20 kids from S3. Participants and teachers were invited to ask questions about our reproductive health research and future careers in STEM. Ginnie Clark outlined the CRH's key research themes to the students, inviting them to ask questions about our work. Rocio (Maybin lab), Grace (Mitchell lab) and Nikki (Pollard lab) facilitated the workshop which was thoroughly enjoyed by the group of budding young scientists. |
| Year(s) Of Engagement Activity | 2022 |
| Description | CRH takes part in Science Insights - Castlebae High Scool, Liberton High School and Portobello High School |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | There was great excitement as CRH staff welcomed S5 students back into the labs at the end of July for Science Insights 2022. Science Insights is an exciting work experience programme designed to give fifth year Scottish high school pupils a true insight into the work and life of research scientists. This dynamic work experience programme gives students a real insight into the work of research scientists as well as valuable hands on experience. CRH was involved in the following ways: • Triin Õunapuu: Prof Carmel Moran ran a lab taster in ultrasound which Triin helped to facilitate. This activity is a hands-on ultrasound experience called "Imaging Inside-Out". Students were given the opportunity to obtain live images of 3D-printed objects that were embedded in opaque gels using hand-held ultrasound scanners. We also covered the theory and applications of a range of other imaging techniques, such as PET and MRI. Importantly, Triin and the team also had an open discussion about usage of animal models in medical research - from laws/legislations to our personal experiences and views. • Rocio Aguilar Martinez ran a fantastic lab taster session in the Maybin lab. The students were fascinated to learn about her research into Heavy Menstrual Bleeding and sample some lab work. • Francesca Hearn-Yeates (Horne lab) and Grace Forsyth (Mitchell lab) were involved in the CMVM student education session on 29.07.22. |
| Year(s) Of Engagement Activity | 2022 |
| Description | CRUK Scotland St. Andrews Day |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Jeff Pollard featured in the CRUK Scotland's Twitter post on St Andrew's Day, thanking all their supporters in Scotland. Jeff explained why this support is valued in the academic community to help save more lives through research. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment, Keystone Symposia, Florence |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Binzhi was invited to give a plenary talk in Keystone Symposia, Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment, held at the Florence, Italy. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Cancer drug may cause women to grow new eggs, study suggests |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Women treated with a common chemotherapy drug combination have more young eggs in their ovaries afterwards, research has found. A small study indicates that a therapy commonly used to target Hodgkin's lymphoma appears to increase the number of non-growing eggs in women's ovaries. Researchers say it is too soon to link the outcome to fertility, but believe more research is needed to better understand the findings and their implications. Scientists from the University of Edinburgh analysed samples of ovary tissue donated by 14 women who had undergone chemotherapy, and from 12 healthy women. They found that the ovaries from eight of the cancer patients, who had been treated with a drug combination known as ABVD, had a much greater incidence of immature, or non-growing, eggs compared with tissue from women who had received a different chemotherapy, or from healthy women of a similar age. The ovary tissue was seen to be in healthy condition, appearing similar to tissue from young women's ovaries. If further research can reveal the mechanism by which treatment with ABVD results in increased production of eggs, this would aid understanding of how women might be able to produce more eggs during their lifetime, which was until recently thought to be impossible. Researchers had set out to better understand why treatment with ABVD is one of the few cancer drug combinations that does not impact on women's fertility. Future studies will examine the separate impact of each of the four drugs that combine to make ABVD - known as adriamycin, bleomycin, vinblastine and dacarbazine - to better understand the biological mechanisms involved. The study, published in Human Reproduction, was supported by the Medical Research Council. Lead researcher Professor Evelyn Telfer, of the University of Edinburgh's School of Biological Sciences, said: "This study involves only a few patients, but its findings were consistent and its outcome may be significant and far-reaching. We need to know more about how this drug combination acts on the ovaries, and the implications of this." |
| Year(s) Of Engagement Activity | 2016 |
| Description | Cell Symposium : Hallmarks of Cancer. Ghent, Belgium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speaker : Cell-VIB Symposium: Hallmarks of Cancer |
| Year(s) Of Engagement Activity | 2016 |
| Description | Challenge your expert session (ESMO) Oxford, UK |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Discussion forum |
| Year(s) Of Engagement Activity | 2017 |
| Description | Charles Easton Seminar Series |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tumor Associated Macrophages - from Mechanism to Therapy" |
| Year(s) Of Engagement Activity | 2016 |
| Description | Chemotactic Cytokines Gordon Research Conference, Girona, Spain |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A chance to uncover the advanced improvements in Biological Chemistry, Cytokines and Chemotactic Cytokines at this important Conference. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Clinical Trials Collaboration with Ugandan University in Development, Edinburgh and Uganda |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Fiona Denison hosted a two day multidisciplinary meeting this autumn with colleagues from Makerere University, Uganda. The discussion explored the clinical trial partnership and the design and development of a medical device for obstetric haemorrhage. Fiona Denison also ran a workshop in October on developmental care for preterm babies in Kampala, Uganda in collaboration with Makerere University. |
| Year(s) Of Engagement Activity | 2019 |
| Description | College of Medicine and Veterinary Medicine Summer Work Experience, Edinburgh |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | High school students toured around The Queen's Medical Research Institute and engaged in interactive sessions with Roseanne Rosario, Mike Miller and Mike Rimmer. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Common steroid could reduce heavy menstrual bleeding - Hilary Critchley |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Common steroid could reduce heavy menstrual bleeding Women who experience heavy menstrual bleeding could have their blood loss reduced by treatment with a common anti-inflammatory steroid, research by Hilary Critchley and colleagues suggests. The study could pave the way for dexamethasone to be used as a safe, effective therapy - the first new class of treatment for heavy menstrual bleeding in nearly 20 years. It is the first time an anti-inflammatory steroid has been trialled to treat this common health problem, which affects around one in four women in the UK and can persist for years. There was extensive press coverage on these findings in early August 2021, including The Times and The Daily Mail. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.thetimes.co.uk/article/dexamethasone-steroid-treatment-for-covid-19-reduces-menstrual-bl... |
| Description | Covid-19 linked to complications during pregnancy |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Usher PI and CRH Associate Sarah Stock is co-lead of the Covid in Pregnancy study (COPS). There was a huge amount of international and national (broadcast and print) coverage generated when this data was published in January 2022, involving interviews with Sarah and pregnant women case studies. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Croucher Summer Course & Symposium : Advances in Immunology in Health & Diseases, Hong Kong |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speaker/Lecturer/Assessor : Conference which focussed on such immunology research, including abnormal immune level responses that lead to cancer and autoimmunity development. This is essential in elucidating the cause of common disorders and could facilitate the design of more specific, efficient and safe therapies through immunoregulation. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Dan L Duncan Lecture; Breast Disease Program, Baylor College of Medicine, Houston, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oncology Lecture |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.bcm.edu/centers/cancer-center/events |
| Description | Dewitt Goodman Seminar, Columbia University |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A talk in the Dewitt Goodman Seminar series at Columbia University in New York. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Distinguished guest lecture : University of Pennsylvania School of Medicine, Institute for Regenerative Medicine at UPENN, Philadelphia, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Distinguished lecture series |
| Year(s) Of Engagement Activity | 2018 |
| Description | Distinguished guest lecture; Kitasato University, Tokyo, Japan |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Distinguished guest lecture. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Distinguished guest lecture; Washington University, St Louis, Ohio. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oncology and cancer biology |
| Year(s) Of Engagement Activity | 2018 |
| Description | ESHRE 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The second online ESHRE took place from June 26 - July 1, 2021. EHSRE is the biggest reproductive health and embryology conference in Europe and takes place annually. It was great to see such an enthusiastic CRH presence, with all sessions well attended and received. |
| Year(s) Of Engagement Activity | 2021 |
| Description | ESHRE 2021 - Gabriele Matilionyte |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | PhD student Gabriele Matilionyte (Mitchell lab): Session title: Male and female fertility preservation: new insights from the laboratory Session type: Selected oral communications Comparison between effects of exposure to platinum-based chemotherapeutics (cisplatin and carboplatin) on Sertoli cell number and functions in immature human testicular tissues. This was followed by a lively and popular Live Q&A. |
| Year(s) Of Engagement Activity | 2021 |
| Description | ESHRE 2021 - Richard Anderson |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Richard Anderson Session title: The future of fertility preservation Session type: Invited session |
| Year(s) Of Engagement Activity | 2021 |
| Description | ESHRE 2021 - Rod Mitchell |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Rod Mitchell Session title: Are we ready for the future of male fertility creation & preservation - part 1 Session type: Precongress Course I. Medical treatment as an alternative strategy to preserve male fertility before cancer treatment II. How to set up a fertility preservation program |
| Year(s) Of Engagement Activity | 2021 |
| Description | ESRC Festival of Social Science webinar, titled: 'The Price of Periods: Prisons, Poverty, Politics - HIlary CRitchley |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | In November, Hilary Critchley participated in the ESRC Festival of Social Science webinar, titled: 'The Price of Periods: Prisons, Poverty, Politics.' Hilary also joined the webinar for Public Policy Projects: A Women's Health Agenda, Roundtable Six: 'The Inevitability of Womanhood - Menses and Menopause'. Hilary's contribution was "Tackling taboos and talking about periods". |
| Year(s) Of Engagement Activity | 2021 |
| Description | EUROGIN (EUROGIN, Düsseldorf, Germany, 10 - 13 April 2022) " - Kate Cusheri |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Kate Cuschieri will co-chair two sessions at the forthcoming meeting of EUROGIN (EUROGIN, Düsseldorf, Germany, 10 - 13 April 2022) "Clinical applications of emerging sequencing technologies" and "New strategies for monitoring disease in the test of cure population." The EUROGIN meeting attracts a multidisciplinary mix of clinical, epidemiological and behavioural researchers. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Edinburgh Centre for MS Research, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Irene Molina gave a talk at the Edinburgh Centre for MS Research. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Edinburgh Infectious Diseases 11th Annual Symposium, |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Kate also spoke at Edinburgh Infectious Diseases 11th Annual Symposium, "Together Again", held at Roslin on 23.06.22. She discussed the impact of HPV vaccination in Scotland and implications for global elimination of cervical cancer. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Endometriosis Research Now, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Andrew Horne organised an Endometriosis Scientific Research Conference 'Endometriosis Research Now' with Philippa Saunders, Jackie Maybin, Doug Gibson and psychologist Sarah Young. The conference was held for those with endometriosis, their supporters and friends in collaboration with World Endometriosis Research Foundation, the World Endometriosis Society and EXPPECT Endometriosis Team. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Endometriosis discussion in 'Bun in the oven' podcast - Andrew Horne |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Endometriosis discussion in 'Bun in the oven' podcast Andrew features in an episode of the popular 'Bun in the Oven' podcast, talking about endometriosis. He discusses diagnosis times, signs, symptoms, treatment options, and the importance of continued research into this condition. Have a listen here Andrew was recently selected to be on the on the panel for the Edinburgh Medical Debate 2021 entitled 'Surviving Covid-19 - The future of the NHS'. The other speakers included Linda Bauld and Carey Lunan. Further information He was also recently invited to speak about endometriosis research and treatment at a high profile 'Women in Science' event, run by the Fondation L'Oreal. There were 40 speakers attending from 30 countries. Andrew was on the panel for the |
| Year(s) Of Engagement Activity | 2021 |
| Description | Endometriosis study at the MRC Centre for Reproductive Health, Edinburgh |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | The MRC Scottish Showcase event brochure featured a case study on endometriosis research undertaken by Andrew Horne and his team at the EXPPECT Centre for Pelvic Pain and Endometriosis, at CRH. |
| Year(s) Of Engagement Activity | 2019 |
| Description | European Academy of Pediatrics Meeting in October, |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | James Boardman has been invited to give a talk at the European Academy of Pediatrics Meeting in October, entitled: 'Socioeconomic deprivation and the preterm infant: how does it affect outcome?' |
| Year(s) Of Engagement Activity | 2022 |
| Description | European Network of Trainees in Obstetrics & Gynaecology, Poland |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Michael Rimmer was chosen to represent the UK at the European Network of Trainees in Obstetrics & Gynaecology (ENTOG) in an exchange in Poland based in Lublin and Warsaw. He attended a conference in Warsaw, the theme of which was 'Reproductive Health and Prenatal Testing'. |
| Year(s) Of Engagement Activity | 2019 |
| Description | European Society for Contraception virtual seminar May 7/8 on 'Emergency contraception'.- Sharon Cameron |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sharon Cameron gave an invited lecture at the European Society for Contraception virtual seminar May 7/8 on 'Emergency contraception'. This included the findings of the recent successful Bridge -it study , which was led from University of Edinburgh. |
| Year(s) Of Engagement Activity | 2021 |
| Description | European Society for Medical Oncology (ESMO) Congress, Madrid 'Challenge your expert' Session |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | 'Challenge your expert' - Management of patients on immunotherapy. Discussion. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Expert reaction to abstract on air pollution and ovarian reserves, Science Media Centre |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Richard Anderson was quoted on an article featured on the Science Media Centre website. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Expert reaction to new report from the Environmental Audit Committee on toxic chemicals in the home, Science Media Centre |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Rod Mitchell was quoted on an article featured on the Science Media Centre website. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Expert reaction to study looking at chemicals in plastics and childhood obesity, |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Rod Mitchell was quoted on an article featured on the Science Media Centre website. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Expert reaction to study on stress in early pregnancy and sperm count in male offspring, Science Media Centre website |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Rod Mitchell was quoted on an article featured on the Science Media Centre website. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Exploring the science behind the headlines - In-utero exposure to painkillers and future health, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Rod Mitchell was invite to talk about environmental disruptors at the Old Bell Inn Edinburgh. |
| Year(s) Of Engagement Activity | 2019 |
| Description | FSRH 'Hot Topic' online event |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Andrew Horne presented virtually at this online event run by The Faculty of Sexual and Reproductive Healthcare on 20.07.22. He spoke about chronic pelvic pain causes and management, and took part in a lively Q&A. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Feinstein 1st International Symposium on Inflammation. New York |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | June 2022 Feinstein 1st International Symposium on Inflammation. New York |
| Year(s) Of Engagement Activity | 2022 |
| Description | Fertility 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Staff and stuents attended this meeting and was very succesful in talks and posters etc |
| Year(s) Of Engagement Activity | 2022 |
| Description | Fertility Preservation in Disorders of Sex Development at the European Society of Paediatric Endocrinology in Rome. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Also in September, Rod Mitchell gave an invited lecture on Fertility Preservation in Disorders of Sex Development at the European Society of Paediatric Endocrinology in Rome. Rod then visited Nice to give a lecture on Fertility Preservation in Klinefelters Syndrome at the European Society of Human Reproduction and Embryology Campus Workshop. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Fertility Preservation public lecture A fertile future - preserving fertility in young people with cancer |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Public lecture as well as meeting: A fertile future - preserving fertility in young people with cancer |
| Year(s) Of Engagement Activity | 2017 |
| Description | Fragile X-associated premature ovarian insufficiency, Wellbeing of Women |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | PHD Student Roseanne Rosario describes her ground-breaking research into Fragile X- associated premature ovarian insufficiency. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Frozen tissue service offers fertility hope for children with cancer |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Young people with cancer are set to benefit from a new service that aims to restore their fertility following chemotherapy. Scientists are freezing tissue from the reproductive organs of boys and girls as young as one, which can be re-implanted once they reach adulthood. The announcement follows the birth of the first baby in the UK to be born after his mother had a transplant of her own, previously frozen ovary tissue. The 33-year-old from Edinburgh had a section of her ovary removed 11 years ago after being diagnosed with a rare form of cancer. Following her chemotherapy, doctors re-implanted the tissue last year in the hope of restoring her fertility. The woman, who wishes to remain anonymous, conceived naturally and gave birth to a healthy baby boy earlier this month. Her success, which was led by a team at the University of Edinburgh, has been welcomed as a milestone in the effort to help young people with cancer and other diseases whose treatment threatens their fertility. Chemotherapy and radiotherapy are known to have serious side effects on reproductive organs. If children are given these treatments before they reach puberty, it can render them infertile in later life. By removing the tissue from children before they undergo cancer treatment, it is possible to protect it from side effects that can render patients infertile. Scientists say restoring fertility in men can be more challenging than in women because the testicular tissue of prepubescent boys is not yet able to produce sperm. By comparison, girls are born with a full complement of egg cells which can be frozen for transplant at a later stage. Researchers say the new service, led from the University of Edinburgh, is open to NHS patients. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Future treatment for male infertility |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Rod Mitchell spoke to the press about revolutionary fertility transplants in males following cancer treatment. In 2022, Rod and his colleagues will seek permission to start clinical trials of the treatment in humans for the first time. The procedure means childhood cancer survivors will be able to father children who are biologically their own, instead of relying on sperm donors. Read some of these press articles here: The Sunday Post; The Daily Mail; The Telegraph There is ongoing broadcast and press interest in this topic, which is expected to generate further coverage in 2022. Covid-19 in pregnancy Read Sarah Stock's expert commentary in this important BBC article discussing Covid-19 and pregnancy, including the rise in pregnant women needing treated in ICU (15.10.21). She said "there is evidence Covid-19 led to higher premature birth rates and probably caused more stillbirths as well", and added "being pregnant affects your response to infections. We know that pregnant women are more susceptible to viruses - and this is probably what we're seeing with Covid-19." Sarah appeared on Good Morning Scotland and Reporting Scotland to raise awareness that pregnant women could be severely affected by Covid-19 infection (and explained why), whilst encouraging this group to get vaccinated. She has also recently provided expert commentary to the investigation into an increase in newborn baby deaths in Scotland. Sarah told the BBC and The Herald that the virus could have led to an increase in infections in expectant mothers and premature deliveries as a result. Read more here: Investigation into spike in newborn baby deaths in Scotland - BBC News In the above BBC article, Sarah highlighted the Covid-19 in Pregnancy Study (COPS), which she co-leads. New data for Scotland on confirmed cases of COVID-19 occurring in pregnancy, and COVID-19 vaccination for pregnant women, has been released. The COVID-19 in Pregnancy in Scotland (COPS) study is co-led by Public Health Scotland and the University of Edinburgh. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.sundaypost.com/fp/childhood-cancer-patients-infertility/ |
| Description | GEM3 Trial Information Day, Edinburgh |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Andrew Horne's research team hosted a very successful GEM3 Trial Information Day on 12 April in Edinburgh, with nearly 50 attendees, representing over 30 sites. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Global Research and Learning Agenda for Contraceptive-Induced Menstrual Changes |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | CRH's Hilary Critchley and Jackie Maybin are two members of the contraceptive-induced menstrual changes (CIMC) Task Force. It was launched in April 2021 and brings together 28 menstrual health and family planning experts from 18 organizations and 10 countries. The Task Force was responsible for creating and advancing a new agenda for addressing the issue of CIMCs in the family planning (FP) and menstrual health (MH) fields, as well as within the wider sexual and reproductive health and rights (SRHR) sector. You can read the Global Research and Learning Agenda for Contraceptive Induced Menstrual Changes in |
| Year(s) Of Engagement Activity | 2022 |
| Description | Gordon Research Conference on Germinal Stem Cell Biology, Hong Kong |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gabriele Matilionyte attended Gordon Research Conference on Germinal Stem Cell Biology in Hong Kong and presented a poster. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Guardian article on menstruation |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Guardian article on menstruation Hilary Critchley contributed to this The Guardian news piece (10.04.22) focusing on menstruation and the importance of continued research to improve treatment options. |
| Year(s) Of Engagement Activity | 2022 |
| Description | HPV Research hosted a virtual extra-ordinary meeting of the Scottish HPV Investigators Network (SHINe) on 27.09.22 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | HPV Research hosted a virtual extra-ordinary meeting of the Scottish HPV Investigators Network (SHINe) on 27.09.22 which focused on HPV developments in Italy including HPV based primary screening, self-sampling and management of women post treatment for cervical neoplasia. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Hilary Critchley delivered the 2022 Kempers Lecture entitled: "Tackling Taboo and the Mysteries of Menstruation" at the prestigious Mayo Clinic, Alix College of Medicine in Rochester, USA. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 13.06.22 Hilary Critchley delivered the 2022 Kempers Lecture entitled: "Tackling Taboo and the Mysteries of Menstruation" at the prestigious Mayo Clinic, Alix College of Medicine in Rochester, USA. This lecture was very well received. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Hilary Critchley's opinion piece in The Scotsman |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Hilary Critchley has written an excellent opinion piece for The Scotsman (08.06.21) which focuses on heavy menstrual bleeding (HMB) and her groundbreaking menstrual health research at CRH. Please have a read of it by clicking this link. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.scotsman.com/news/opinion/columnists/prof-hilary-critchley-periods-are-an-amazing-natura... |
| Description | How to Recognize and Treat an Ectopic Pregnancy, The New York Times, USA |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Andrew Horne contributed to an article on ectopic pregnancy in the New York Times |
| Year(s) Of Engagement Activity | 2019 |
| Description | Human tumor-associated macrophage transcriptional landscape in sold tumors, Immun-oncology day, Brussels |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Luca Cassetta gave a talk titled Human tumor-associated macrophage transcriptional landscape in sold tumors at the Immun-oncology day in Brussels on 1st February. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Inflammation Symposium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Public engagement event: Inflammation to improve reproductive health across the life-course. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Inflammation in the brain and body' symposia, The College of Medicine and Veterinary Medicine, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Veronica Miron presented a talk and Irene Molina a poster at the College of Medicine and Veterinary Medicine: 'Inflammation in the brain and body' symposia. This was presented at the University of Edinburgh, Scotland. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Innovation in breast cancer; Madrid, Spain |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Two-day international scientific programme aims to provide state-of-the-art information on breast cancer achieving a balance of clinical, translational, and basic research and providing a forum for interaction, communication, and education for medical oncologist, gynaecologists and other specialists with a special interest in breast cancer. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Inside The Zoo on BBC Scotland - Kirsten Wilson |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Kirsten Wilson, Specialist Assay Lab and Duncan Lab, was featured on Inside The Zoo on BBC Scotland (Series 2, Episode 3; available on BBC iPlayer) monitoring this year's Giant Panda breeding season at RZSS Edinburgh Zoo. This is both part of Kirsten's job and her PhD research. You can access this episode here. Well done Kirsten! Whilst unfortunately the breeding season was not successful in producing a panda cub, Kirsten found monitoring the pandas on-site at Edinburgh Zoo to be a fantastic and worthwhile experience. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.bbc.co.uk/iplayer/episode/m00118r6/inside-the-zoo-series-2-episode-3 |
| Description | Institute of Immunity and Transplantation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Distinguished guest lecture : Macrophage maleficence in cancer |
| Year(s) Of Engagement Activity | 2018 |
| Description | Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Infection, Immunity and Inflammation |
| Year(s) Of Engagement Activity | 2017 |
| Description | Interdisciplinary Life Science Seminar Series (LSSS), University of Zurich |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Distinguished guest lecture |
| Year(s) Of Engagement Activity | 2016 |
| Description | International impact of the Telemedicine Medical Abortion Study |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The recently published telemedicine study conducted by Sharon Cameron's research group (including CRH PhD student John Reynolds-Wright) has had international impact. The study has been referenced as part of the International Federation of Obstetrics and Gynaecology (FIGO) position statement on telemedicine for medical abortion care which will help groups across the world lobby for access to safe telemedicine abortion treatment. The study has also been considered by the US Food and Drug Administration (US FDA) in their decision to reverse a decision made by the Trump administration to prevent remote prescription and administration of Mifepristone. This means that EMA can now be accessed much more easily and via telemedicine across the USA. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Interview for BBC Radio Scotland's 'Brainwaves', United Kingdom |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor James Boardman, neonatologist and Scientific Director of the Jennifer Brown Laboratory in Edinburgh, talks about his research into the effects of a baby being born too small or too soon on how the brain develops outside the womb. Its a fascinating, engaging and emotionally challenging role which sees him tread a path between time working as an NHS consultant with premature babies in Edinburgh's Royal Infirmary neonatal care unit and conducting research with these tiny babies using state of the art technology and brain imaging techniques to try to understand the causes and consequences of pre-term birth. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Interview with The Indepedent and Talk Radio |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Prof Andrew Horne was interviewed in the Independent and by Eamonn Holmes on TalkRadio where he highlighted the need for increased research funding for endometriosis. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited lectures, 5th EMEL Conference, Dubai |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Andrew Horne gave three lectures outlining his research into endometriosis at the 5th EMEL Conference in Dubai. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited lectures, British Neuropathology Association, the International Society of Magnetic Resonance in Medicine, British Maternal & Fetal Medicine Society, United Kingdom |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | James Boardman gave invited lectures to the British Neuropathology Association, the International Society of Magnetic Resonance in Medicine, and the British Maternal & Fetal Medicine Society. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation, European Academy of Neurology meeting, Oslo |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Veronique Miron presented at the European Academy of Neurology meeting in Oslo. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation, International Society for Neurochemistry Satellite Meeting, Quebec |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Veronique Miron presented at the International Society for Neurochemistry satellite meeting in Quebec. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Jackie Maybin and Ginnie Clark were delighted to launch CRH's new animation at the end of August, 2021 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | 'Typical and Problem Periods' will raise awareness of menstrual problems, and offer support and guidance. The animation clearly and simply describes menstruation, how to identify if periods are not typical, and where to seek help. It also highlights the important research into this topic being carried out by Jackie Maybin and her lab group. Their vital work helps to prevent problematic periods from occurring and develops more effective treatment options. There are English subtitles and a number of additional language options. To access subtitles, go to the Settings wheel (computer) or the three dots (phone) in the corner of the screen and choose Subtitles, then your language of choice. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Jackie Maybin and MSP: Parliamentary Pairing Scheme |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Visits Westminster - return visit TBC |
| Year(s) Of Engagement Activity | 2017,2018 |
| Description | Jackie Maybin appeared on BBC Scotland's 'The Nine' news programme |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | COVID-19 vaccination and menstrual changes Jackie Maybin appeared on BBC Scotland's 'The Nine' news programme to alleviate concerns that the Covid-19 vaccine can impact periods. Jackie said: "There may be a short term effect on menstruation but any such effect is likely to be transient". She went on to reassure women that there is no evidence for any long term effect on fertility and encouraged women to attend appointments for the Covid-19 vaccine. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Jackie Maybin contributes to important women's health articles |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Read Jackie Maybin's views on the importance of improving women's health for all of society, in this Wellbeing of Women blog article. Jackie is the expert in this informative and insightful article in student newspaper, The Tab, which discusses the impact the Covid-19 vaccine may have on menstruation: Jacqueline Maybin, Senior Research Fellow and Consultant Gynaecologist at CRH, was asked why some people's periods are being disrupted by the vaccine. She said: "There have been lots of anecdotal reports of people with menstrual disturbance following Covid-19 vaccination, including changes in frequency, duration, regularity and volume of menstruation. "In the UK, the MHRA have had approximately 4,000 reports of menstrual disturbance via their yellow card reporting system, although actual numbers may be larger due to a lack of awareness of this scheme. Data are also being collected by Dr Kate Clancy at the University of Illinois via a Twitter-based survey." "At this stage, it is difficult to be certain regarding the mechanisms causing these effects. It may differ from person to person. The brain, ovaries and womb interact to control the menstrual cycle. So, menstrual disturbance may be due to effects on the part of the brain that controls the reproductive hormones, effects on the ovaries or effects directly on the lining of the womb (which is what is shed during a period)." "In times of stress, the female system is designed to temporarily down-regulate to prevent against pregnancy and conserve energy. This brain-level effect may explain some of the changes in menstruation observed during the pandemic or after vaccination." "The Covid-19 vaccination itself is designed to initiate an immune response in the body to protect against future Covid-19 infection. The resulting inflammation may transiently affect the ovaries, altering their hormone production over one or two cycles. The inflammation may also potentially alter how the womb lining breaks down, causing heavier periods. These effects could lead to temporary changes in menstrual symptoms that should spontaneously resolve." "It is important to emphasise that any effects of the vaccine are likely to be short lived and much less severe than those associated with Covid-19 infection, which has also been linked with menstrual disturbance. Women who are called for the vaccine shouldn't be deterred from attending." |
| Year(s) Of Engagement Activity | 2021 |
| Description | Jackie Maybin on BBC Good Morning Scotland |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Jackie appeared on GMS to offer reassurance to women who are yet to get vaccinated against Covid-19 (16.09.21) You can listen to CRH's Jackie Maybin speaking on BBC Good Morning Scotland (at 2:41:18) about the Covid19 vaccine causing a possible (transient) disruption to the menstrual cycle. Jackie also speaks about the importance of pregnant women getting vaccinated and whether the vaccine could have any impact on fertility. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Kampala Workshop, Kampala, Uganda |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Fiona Denison successfully led a 3 day workshop in Kampala, Uganda. The delegation agreed to focus on 3 projects related to neonatal and perinatal causes of death, training of personnel, and emergency care. Potential funders were discussed to include the MRC, NIHR, EPSRC and GCRF. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Keynote Speaker, 1st Symposium of the Occitanie Network Monocytes/Macrophages, Montpelier, France |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Internationally renown experts in the field of macrophage ontogeny, and macrophage role in tissue regeneration and diseases. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Keynote speaker, 2nd Symposium on Cellular Crosstalk in the Tumor Microenvironment, Georg-Speyer Haus, Frankfurt |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | keynote lecture - Dynamic interplay between macrophages and tumor cells promotes malignancy |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.georg-speyer-haus.de/fileadmin/images/sonstige_Veranstaltungen/Program_2Symposium_Oct_13-... |
| Description | Klenk Symposium, Speaker |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tissue regeneration, wound healing and fibrosis: Translating basic concepts into regenerative therapy. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lack of cash hinders research into condition affecting 10% of women, The Scotsman website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Andrew Horne highlighted that lack of funding hinders endometriosis research in an article that he co-wrote for The Scotsman. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Lloyd Cox Memorial Lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Richard Anderson gave the Robinson Research Institute's annual Lloyd Cox Memorial Lecture virtually on 29.09.22. Lloyd Cox was a pioneer in reproductive medicine and champion of women's health and this was a great honour for Richard. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Lucy Whitaker (Horne lab) attended the British Society for Gynaecological Endoscopy annual meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lucy Whitaker (Horne lab) attended the British Society for Gynaecological Endoscopy annual meeting to present findings from the ESPriT2 trial and other NIHR funded endometriosis trials (22.04.22). |
| Year(s) Of Engagement Activity | 2022 |
| Description | Lucy Whitaker presented a summary of EXPPECT's trials in endometriosis and Andrew Horne |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lucy Whitaker presented a summary of EXPPECT's trials in endometriosis and Andrew Horne led a workshop to identify challenges in endometriosis research. |
| Year(s) Of Engagement Activity | 2021 |
| Description | MRC Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Festival - endometriosis |
| Year(s) Of Engagement Activity | 2017 |
| Description | MRC Scottish showcase at Scottish Parliament, United Kingdom |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | CRH attended the MRC Scottish showcase at Scottish Parliament on 6 February, along with eight other MRC Scottish Centres, to highlight the vital work we do in fertility preservation in young cancer patients and research into obesity in pregnancy. Rod Mitchell and Emma Johns ran an interactive stand to inform politicians on their current research and the impact it is having in Scotland, the UK and beyond. The CRH researchers offered MSPs the opportunity to look at testis tissue under a microscope and view a video about fertility preservation, as well as learning more about the impact of obesity in pregnancy and how the Metabolic Antenatal Clinic offers multi-disciplined support from doctors, midwives and dieticians to help support pregnant women. |
| Year(s) Of Engagement Activity | 2019 |
| Description | MS Frontiers, Bath, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Irene Molina, postdoc Lindsey Forbes, and Veronique Miron presented at the MS Frontiers meeting in Bath. |
| Year(s) Of Engagement Activity | 2019 |
| Description | MS Master Class organized by the Northern Ireland MS network. - Irene Molina-Gonzalez |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Miron lab Postdoc Irene Molina-Gonzalez was invited to give an oral presentation on her work on brain repair at the virtual MS Master Class organized by the Northern Ireland MS network. Veronique presented Niamh McNamara's work on microglia in brain development at a virtual symposia she chaired, as part of the large international conference Euroglia. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Male Infertility Initiative |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | A new global initiative has been set up to develop a core outcome set for future male fertility trials. Infertility affects about one in six couples, with male factor infertility causing around a third of overall cases. Core Outcome Measures for Infertility Trials (COMMIT) will be made up of clinicians, researchers and men with infertility from 25 different countries. Michael Rimmer, ECAT Clinical Research Training Fellow in the Mitchell lab, is one of five researchers who form the 'core-working group', to co-ordinate this new initiative. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.ed.ac.uk/centre-reproductive-health/commit |
| Description | Male contraception awareness raising |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | John Reynolds-Wright has responded to media enquiries from The Guardian / Observer, The BBC, and 'The Prude' (a new sexual health platform), concerning male contraceptives and telemedicine abortion care. Coverage is expected in the coming weeks - keep an eye on Twitter. Meanwhile, Richard Anderson provided expert commentary to this article. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Male contraception coverage |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Richard Anderson contributed to this article on male contraception. What Birth Control for Men Will Change, and What It Might Not Richard also contributed to an ESHRE press release which was created in support of his oral presentation at the 38th Annual Meeting of ESHRE. This press release reassuringly highlighted that having a baby after breast cancer does not negatively impact a woman's chance of surviving the disease. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Male contraception put to the test in Manchester and Edinburgh, Manchester and Edinburgh |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Study participants or study members |
| Results and Impact | Couples in Edinburgh and Manchester are being invited to take part in a ground-breaking international study trialling a new form of male contraception. The study is being co-lead by Richard Anderson, from the University of Edinburgh's MRC Centre of Reproductive Health, along with staff from Saint Mary's Hospital and Manchester University NHS Foundation Trust group. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Male contraceptive trial attracts media attention - Richard Anderson and John Reynolds-Wright |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Richard Anderson and John Reynolds-Wright have been speaking to print and broadcast media about the future creation of a male contraceptive pill. John led a trial at CRH using a rub-on gel, which is made of a combination of testosterone (the male sex hormone) and Nesterone (synthetic progesterone, a hormone involved in sperm production amongst a plethora of other functions). The gel works by 'turning off' the part of the brain that instructs the testicles to make sperm. The resounding success of the trial is very exciting progress and it is hoped that the creation of a male pill will offer an additional contraception option to couples. Read more about this study and the male contraceptive pill concept in this Telegraph article and in this Euronews online piece. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.telegraph.co.uk/health-fitness/body/male-fertility-pill-men-finally/ |
| Description | Medical breakthrough could help cancer patients have children, ITV media interview |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Dr Rod Mitchell was interviewed for his expert opinion on ITV News at Ten and The Daily Mail newspaper following the first live birth of a primate after its transplantation of prepubertal testicular tissue. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Metastasis and the Tumor Microenvironment |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speaker Major symposium 'Mestastasis and the Tumor Microenvironment', 2017 Annual Meeting of the American Association for Cancer Research, Washington USA. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Miami Winter Symposium 2016 'Inflammation' |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sessions focussed on the impact of inflammation on cardiovascular metabolism, nervous system, and cancer |
| Year(s) Of Engagement Activity | 2016 |
| Description | Midlothian Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Rocio Martinez Aguilar (pictured right) from the Maybin lab and Ginnie Clark had their application accepted for the Midlothian Science Festival. They are taking part in a 'Meet the Scientist' session in this year's online programme, in October. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Minister of Public Health and Sport visits Tommy s Metabolic Clinic |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Linked to Obesity consultation period |
| Year(s) Of Engagement Activity | 2017 |
| Description | Monocyte/Macrophage/DC: tissue interaction talk at Erasmus, University Medical Center, Rotterdam |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Jeff Pollard gave the Keynote talk at the "Monocyte/Macrophage/DC- tissue interaction" symposia at the Erasmus, University Medical Center, Rotterdam on 20th December followed by a workshop to students on the 21st. |
| Year(s) Of Engagement Activity | 2018 |
| Description | NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital London; Fibrosis Research Group, Inflammation, Repair & Development Section |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Distinguished Guest Lecture/Assessor. |
| Year(s) Of Engagement Activity | 2016 |
| Description | National coverage highlights Sarah Stock's important research |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Almost 4,000 pregnant women have taken up a Covid-19 vaccine in Scotland, with no adverse effects reported. These figures have been published for the first time by University of Edinburgh researchers including CRH's Sarah Stock, and Public Health Scotland. The joint study is known as Covid-19 in Pregnancy in Scotland (COPS). Please see link here to access the complete data. Sarah Stock, consultant and reader in maternal and fetal medicine at the at CRH and COPS co-lead, said: "We know that complications from Covid-19 while pregnant can be serious for both women and babies. For example, Covid-19 increases the risk of early birth." "It is understandable that pregnant women may be anxious about getting the Covid-19 vaccine, but I hope that the results shared today reassure women who are seeking to make informed choices for themselves and their babies." "It should also give confidence to midwives, doctors, vaccinators and others who are in a position to support them in their decision." |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.thetimes.co.uk/article/only-2-per-cent-of-new-mothers-had-received-jab-v6zcq39b3 |
| Description | Netherlands OGO Congress on 31 March 2021. - Andrew Horne |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Andrew Horne delivered an invited online lecture entitled 'The holistic approach to endometriosis' at the Netherlands OGO Congress on 31 March 2021. Andrew delivered a webinar to over 150 general practitioners on endometriosis on 13 May |
| Year(s) Of Engagement Activity | 2021 |
| Description | New guidelines launched for diagnosis and management of Endometriosis |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Andrew Horne, who was member of the Core Guideline Development Group, said: "It was a pleasure to be involved in updating the ESHRE Guideline for endometriosis which, I think, will be incredibly useful for doctors and for patients. It will help direct clinicians how to diagnose and manage endometriosis in a more effective and evidence-based manner." |
| Year(s) Of Engagement Activity | 2022 |
| Description | New project to beat 'hidden' disease puts patients at its heart |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Women with endometriosis - a painful, debilitating disease linked to infertility - are being invited to join a research project that aims to shape possible future treatments. The initiative will team up women with endometriosis, carers, and healthcare professionals to prioritise areas of research they believe have not yet been tackled. The project's aim is to identify the top ten leading challenges that women with endometriosis face, with a view to influence the prioritisation of future research in this area. Endometriosis affects an estimated 176 million women. It occurs when tissue similar to the lining of the uterus is found elsewhere - most commonly in the abdomen, on the ovaries, bladder and bowel. This misplaced tissue behaves like the lining of the uterus, bleeding every month and creating local inflammation. It is associated with chronic pain, heavy bleeding, and infertility, and can impact on mental, and social wellbeing. Anyone affected by endometriosis - patients, carers, employers and professionals - is invited to contribute to the project through a survey which can be found here: Endometriosis priority-setting survey The project is being run in partnership with the James Lind Alliance, and is supported by the World Endometriosis Research Foundation (WERF). Professor Andrew Horne, who is leading the research at the University of Edinburgh's MRC Centre for Reproductive Health, said: "Endometriosis is as common in women as diabetes and asthma, and yet it fails to attract the same attention, support and funding as those diseases. "It is important that we ensure medical researchers are focussing on the issues that really matter for women living with this debilitating condition, and deliver treatments that make a genuine difference to their quality of life." |
| Year(s) Of Engagement Activity | 2016 |
| Description | Online event with Colin Duncan - PCOS |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Colin Duncan was the expert speaker in an online webinar on 19.05, organised by The Lowdown. The Lowdown is a women's health platform which was created to educate women on contraception and inform them of the different options available. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Organiser - 4th Annual Symposia. 'A cell for all seasons, Macrophages in health and disease'. Edinburgh |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Annual "Macrophage" meeting to highlight the diversity of research in this area drawing upon local and international speakers. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.ed.ac.uk/centre-reproductive-health/news-events-seminars/events/a-cell-for-all-seasons-m... |
| Description | PET Events |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | The first event was entitled 'Advances in Assisted Reproduction: What Can We Expect?', and took place on 06.10.21.The presentations were enlightening and the combined speakers gave an excellent overview of how fertility preservation and assisted reproduction has progressed to the present day. Speakers included Rod Mitchell and CRH Associates |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://pet.secure.force.com/PETEvents/PETEvent_Overview?id=a2g4J000000tGeh |
| Description | Painkillers in pregnancy |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Pregnant women who take common painkillers could unwittingly be putting the fertility of their unborn daughters at risk, a study suggests. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Paracetamol use in pregnancy can cut female fertility, study finds |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Using painkillers in pregnancy may reduce fertility in subsequent generations, research suggests. Tests in rats found that when a mother was given painkillers during pregnancy, her female offspring had fewer eggs, smaller ovaries and smaller litters of babies than those not exposed to the drugs. Exposed male offspring were also found to be affected at birth - showing smaller numbers of cells that give rise to sperm in later life. However, their reproductive function recovered to normal levels by the time they reached adulthood. Researchers say the findings are significant given the similarities between the reproductive systems of rats and humans, although it is difficult to directly extrapolate these results to pregnant women. The team recommends that pregnant women should stick with current guidelines to use painkillers at the lowest possible dose, for the shortest possible time. Scientists tested the effects of two painkillers in pregnant rats - paracetamol and a prescription-only painkiller called indomethacin, which belongs to the same class of drugs as ibuprofen and aspirin. Rats were given the drugs over the course of several days - four days for indomethacin or nine days for paracetamol. The effects of the drugs were seen within one to four days of the start of treatment. Scientists say that because the pace of foetal development in humans is slower than it is in rats, it is hard to say from this study how this would translate in human use. In addition to affecting a mother's immediate offspring, the study showed that painkillers taken in pregnancy also affected the subsequent generation of rats. The team found that the resulting females - the granddaughters of the mother given painkillers in pregnancy - also had reduced ovary size and altered reproductive function. Scientists say the results suggest that some painkillers may affect the development of the cells that give rise to eggs and sperm - called germ cells - while a foetus is in the womb. This may be because the painkillers act on hormones called prostaglandins. These are known to regulate female reproduction and control ovulation, the menstrual cycle and the induction of labour. The study has been published in the journal Scientific Reports. It was funded by the Medical Research Council and the Wellcome Trust. Prof Richard Sharpe, who co-led the study at the University of Edinburgh's MRC Centre for Reproductive Health, said the results follow previous research that indicates painkillers should be used with caution during pregnancy. He said: "It's important to remember that this study was conducted in rats not humans, however, there are many similarities between the two reproductive systems. We now need to understand how these drugs affect a baby's reproductive development in the womb so that we can further understand their full effect." Prof Richard Anderson, Elsie Inglis Professor of Clinical Reproductive Science at the University of Edinburgh, who co-led the study, said: "These studies involved the use of painkillers over a relatively long period. We now need to explore whether a shorter dose would have a similar effect, and how this information can be usefully translated to human use." |
| Year(s) Of Engagement Activity | 2016 |
| Description | Physiological Reviews podcast : Pregnancy and Covid-19 focus Hilary Critchley, |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Physiological Reviews podcast : Pregnancy and Covid-19 focus Hilary Critchley, Sarah Stock and Rebecca Reynolds feature in this brilliant podcast episode which has a focus on pregnancy and Covid-19 . |
| Year(s) Of Engagement Activity | 2022 |
| Description | Pint of Science Event - Richard Sharpe |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Public engagement event |
| Year(s) Of Engagement Activity | 2017 |
| Description | Pint of Science Event - male fertility |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Awareness of male infertility |
| Year(s) Of Engagement Activity | 2017 |
| Description | Popular women's health webinar |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Hilary Critchley was chair and moderator of the FIGO webinar entitled 'The causes of abnormal uterine bleeding in the reproductive years.' This popular session, recorded on 18.08.22, was widely accessed by Obstetrics and Gynaecology colleagues across the globe. It focused on imaging classifications for adenomyosis, a new classification system for ovulatory disorders, and a systemic review and meta analysis of the relationship of caesarean scar defect to AUB in the reproductive years. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Postpartum Intrauterine Contraception (PPIUC), Lothian |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Michelle Cooper presented work on Postpartum Intrauterine Contraception (PPIUC) provision in Lothian at the Scottish RCOG Senior Staff meeting in Dunblane 22-23rd Feb, and won the prize for best trainee presentation. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Pre-term birth clinic launch |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Launch of pre-term birth clinic |
| Year(s) Of Engagement Activity | 2018 |
| Description | Progress Educational Trust (PET) event on 09.02.22 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Mike Rimmer spoke at the Progress Educational Trust (PET) event on 09.02.22 discussing patient safety in IVF. His discussion topic was Ovarian Hyperstimulation Syndrome (OHSS). The event was attended by over 300 people and will be available on the PET YouTube page in the coming weeks. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Progress Educational Trust event, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Colin Duncan appeared on the panel for the 2019 Progress Educational Trust event. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Dr Rod Mitchell has received media wide attention after the publication of the following Research Article: FETAL DEVELOPMENT Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model |
| Year(s) Of Engagement Activity | 2016 |
| Description | Public Lecture: Preterm Birth: Can we do better? (Lecture series) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Lecture series |
| Year(s) Of Engagement Activity | 2017 |
| Description | Q&A discussion, European Interagency Security Forum |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Andrew Horne and Prof Philippa Saunders led a roundtable discussion and extensive Q and A with members of the public about endometriosis. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Quiz a Whiz, Royal Society of Edinburgh, Edinburgh |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Hilary Critchley further addressed the need to more openly discuss the topic of menstruation in her online RSE event 'Quiz a Whiz'. |
| Year(s) Of Engagement Activity | 2019 |
| Description | RAIDS European Consortium, Institut Curie, Paris, France |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | RAIDs is a multidisciplinary co-operation between academic clinical centers, Small medium enterprises and translational research platforms. It combines Next Generation Sequencing (NGS) and Reverse Phase Protein array (RPPA) in a large patient population prior to standard therapy. In addition, high throughput screening techniques have been performed in Cervical Cancer cell lines, allowing to identify new drugs of relevance for advanced stage multi resistant Cervical Cancer. These molecules are to be validated in preclinical mouse models. Ongoing studies will assess in vitro efficacy of drug targeting according to molecular phenotypes. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.raids-fp7.eu/project-overview.html |
| Description | RCOG Blair Bell 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Staff and students submitted poster to this meeting and was succesfull - Alex Viner, Magdalena Thiel, Mike Rimmer |
| Year(s) Of Engagement Activity | 2022 |
| Description | RCOG World Congress (9-12 June 2021). - Andrew Horne |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Andrew Horne delivered two invites lectures ("Drug repurposing for the treatment of endometriosis" and "The impact of fibroids and fibroid surgery on reproductive outcomes") at the RCOG World Congress (9-12 June 2021). |
| Year(s) Of Engagement Activity | 2021 |
| Description | RCOG careers day, London |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sarah Murray led the instrumental delivery workshop at the RCOG careers day in London as part of her role as Vice Chair of the National Trainees Committee. Over 300 delegates attended the event to learn about obstetrics and gynaecology as a career and have a go at some of the practical aspects of the job. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Radio 4 - 28 ish days later |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | You may have heard Radio 4 airing the popular '28ish days later' series during lunch times in July. Andrew Horne, Jackie Maybin and Evelyn's Telfer all contributed to different episodes in this fantastic series which discussed the menstrual cycle and women's health. This series is still available on BBC Sounds, Spotify and Apple Podcasts in its entirety. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Reproductive Biology Research Talk, James Gillespie High School, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | John Reynolds-Wright gave a talk about abortion to high school students at James Gillespie High School. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Research Roundup: Gum Disease and Alzheimer's, a Cancer Vaccine, Cold Plasma and More, BioSpace Website |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Jeff Pollard was quoted in an article "Research Roundup: Gum Disease and Alzheimer's, a Cancer Vaccine, Cold Plasma and More" by the BioSpace website. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Rod Mitchell attended the Oncofertility Consortium in Pittsburgh USA on 04.05.22 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Rod Mitchell attended the Oncofertility Consortium in Pittsburgh USA on 04.05.22 to speak about fertility preservation. This international, interdisciplinary initiative explores and expands options for the reproductive future of cancer survivors. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Round Table discussion on 'Global Pandemics and Infectious Diseases - what more should we do?' |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Ramya Bhatia of HPG Group was invited to be a panellist in the Round Table discussion on 'Global Pandemics and Infectious Diseases - what more should we do?' organised by Perkin Elmer as part of the World Health Assembly side event. Ramya spoke about learnings from the Covid pandemic that can be used to help improve cervical cancer disease prevention to meet the WHO global target of cervical cancer elimination by 2030. |
| Year(s) Of Engagement Activity | 2022 |
| Description | SRI Denver Colorado, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | staff and students attended this meeting and was successful in orals, posters Mike Rimmer (Mitchell lab) and Aleks Tsolova (Critchley lab) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Sarah Stock creates the preterm birth risk prediction model |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | To improve the prediction of impending preterm birth, CRH's Sarah Stock and colleagues developed and validated a risk prediction model. First they identified clinical risk factors for preterm labour by analysing individual data from five European prospective cohort studies, including 1,783 pregnant European women. They used this information to develop a model to predict risk of spontaneous preterm birth. Researchers validated the model in a study of 2,924 women with signs and symptoms of preterm labour from 26 consultant-led obstetric units in the UK, to demonstrate the difference between predicted and observed outcomes. The study found that using a risk prediction model that included measuring a specific protein concentration analysis alongside clinical risk factors improved the prediction of impending spontaneous preterm birth and was cost-effective in comparison to measuring the protein alone. Sarah Stock said: "The vast majority of women with signs and symptoms of preterm labour don't actually give birth early, but many receive unnecessary hospital admission just in case of preterm birth." "The risk predictor developed by our research team will help women to understand their chance of giving birth early, so they can decide whether or not to have admission and treatment." "We are now working towards linking the predictor to maternity records, so it can easily be used as part of women's care and be continually improved as more women use it." |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dailymail.co.uk/wires/pa/article-9762055/Risk-prediction-model-developed-preterm-births.... |
| Description | Sarah Stock gives expert commentary on the Covid-19 vaccine in pregnancy |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The Herald was looking for a maternal and fetal health expert to speak about pregnant women receiving the Covid-19 vaccine. In this feature, appearing online and in print on 26.05.21, Sarah Stock reassures pregnant women and speaks about ongoing trials saying "There is accumulating real world evidence that the vaccine is safe in pregnancy". The featured case study, a 38 year old woman who had her second child in July, who spoke about feeling comfortable and reassured after receiving the vaccine in her third trimester. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.heraldscotland.com/news/19328418.covid-19-pregnant-mothers-relief-vaccine-wait/ |
| Description | Sarah Stock speaks to the BBC about pregnant women receiving the Covid-19 vaccine |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | CRH's Sarah Stock was asked by the BBC to give her expert opinion on pregnant women being vaccinated against Covid- 19. It aired on BBC News through the day on 10.06.21, and on Radio Scotland. The news segment also features two pregnant women case studies and discusses the first Covid-19 vaccine study for women who are pregnant which has recently been launched in the UK - with Edinburgh playing a key role in the research. Sarah Stock, a Reader in Maternal and Fetal Health in the University's MRC Centre for Reproductive Health, said: "Catching Covid-19 in pregnancy can have serious consequences for mothers and their babies. "This is an important study as it will not only help us understand how best to protect the mothers and babies of today, but also how we can prepare to protect those |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.ed.ac.uk/news/2021/covid-19-vaccine-study-for-pregnant-women-launches |
| Description | School visit x 1 (Mary Erskine) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | School visit led by Andrew Horne |
| Year(s) Of Engagement Activity | 2017 |
| Description | School visit x 2 (The Edinburgh Academy) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | School visit by Colin Duncan |
| Year(s) Of Engagement Activity | 2017 |
| Description | Science Insights |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Science Insights provides an opportunity for high school pupils to spend a week of their summer holidays following a varied programme of online activities hosted by staff from four different University of Edinburgh campuses, gaining a real insight into research and work in many different areas of biological, biomedical and animal sciences. Well done to Roseanne Rosario (pictured), Niamh McNamara and Rocio Martinez Aguilar for their involvement this year. As always, the programme was very popular and beneficial to the students involved. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Science Insights |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Castlebrae Community High School workshop A CRH team of Nikki Graham, Rocio Aguilar Martinez, Grace Forsyth and Ginnie Clark are visiting two classes of students on 25 August to facilitate our 'Ready Steady Grow' workshop. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Science Insights |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | Lab experience for students |
| Year(s) Of Engagement Activity | 2017 |
| Description | Science at the Interface of Industry, Institute of Genetics & Molecular Medicine, Edinburgh |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Aleks Tsolova attended the workshop 'Science at the Interface of Industry' organised by the IGMM. As part of the workshop, attendees were split into 4 teams and tasked to come up with a business idea, develop a business plan and pitch their idea to a "Dragons Den" style panel composed of top scientists working across biotech and the entrepreneurial industry. Aleks and her team of three had the idea of creating a community of mental health first aiders across the University. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Society for Endometriosis and Endometrial Disorders (SEUD) online webinar |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Andrew Horne led a very successful Society for Endometriosis and Endometrial Disorders (SEUD) online webinar on endometriosis on 23.11.22. This was attended by over 300 clinicians and researchers from all over the world. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Society for Reproductive Investigation, Paris |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Erin Greaves presented a poster entitled 'Phenotypic Characterisation of Lesion-resident and Peritoneal Macrophages in a Mouse Model of Endometriosis' at the Society for Reproductive Investigation in Paris. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Speaker - 10th Workshop of European Network of Breast Development and Cancer Labs (ENBDC) Switzerland |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tumour immunology : Macrophage maleficence in cancer. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.enbdc.org/ |
| Description | Speaker - 1st Crick International Cancer Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | leading cancer scientists from all over the world discussing the latest findings in cancer metabolism, the tumour microenvironment, and how the cancer genotype changes over time. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.crick.ac.uk/whats-on/seminars-lectures-symposia/symposia |
| Description | Speaker - CRUK Marshall Symposium, Climping UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Lecture in cancer biology/medicine |
| Year(s) Of Engagement Activity | 2018 |
| Description | Speaker - Cold Spring Harbor Asia Conference, Suzhou, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Conference covering the latest findings across many topics in RNA modifications & Eptranscriptomics. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Speaker - International Symposium of Cancer Immunity and Immunotherapy, Japan |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Symposia on cutting-edge topics in current immunology at 46th Annual Meeting of the JSI, Sendai, Japan. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://icongroup.co.jp/immunology/english/greeting/ |
| Description | Speaker, 2018 Mammalian Reproduction Gordon Research Conference, Lucca, Italy |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lecture on Kruppel-Like Transcription Factors as Downstream Modulators of Female Sex Steroid Hormone Action in the Uterus. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Speaker, 2nd Annual Next Gen Immuno-Oncology Congress, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The congress aims to bring academicians, researchers and scientists from research institutes pharmaceutical, bio-pharmaceutical and biotechnology companies to discuss the latest updates in the development of ADC's, Bispecific Antibodies and Immune Checkpoint Inhibitors. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.mnmconferences.com/2nd-Annual-Next-Gen-Immuno-Oncology-Congress |
| Description | Speaker, 32nd Annual 'Genes and Cancer' meeting, Robinson College, Cambridge, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Genes and Cancer' is a broad-based research meeting focusing on basic and translational cancer research. The meeting is one of the UK and Europe's best cancer research meetings and the meeting is now in its 33rd year. This year's event is focused on four main research themes. They are: 'Gene Regulation in Cancer', 'Ubiquitin Signalling and Inflammation', 'Tumour Metabolism' and 'Model Organisms in Cancer Research'. In addition to these 4 themes there will be a Keynote lecture and short talks will be chosen from submitted abstracts (including short talks for junior principal investigators and short talks for post-docs/students). The main aim of the meeting is to bring together young scientists with some of the world's leaders in cancer research in an informal environment that maximizes interaction between speakers and delegates. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Speaker, 5th International Breast Cancer Course, Insitut Curie, Paris (virtual) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | October 2022 Speaker, 5th International Breast Cancer Course, Insitut Curie, Paris (virtual) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Speaker, 5th International Breast Cancer Course, Insitut Curie, Paris (virtual) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In October, Jeff Pollard was invited to Paris to give a lecture at the 5th International Breast Cancer Course organized by the Institut Curie. The title of his lecture was "The role of myloid cells in breast cancer". |
| Year(s) Of Engagement Activity | 2022 |
| Description | Speaker, 8th Abercrombie Meeting, Royal Microscopical Society, St Catherine's College, Oxford UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Research and education in microscopy, and enabling microscopists to make advances and developments in microscopy, cytometry and imaging. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.rms.org.uk/ |
| Description | Speaker, British Society of Immunology, Edinburgh, UK - Jeff Pollard |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | December 2021 Speaker, British Society of Immunology, Edinburgh, UK |
| Year(s) Of Engagement Activity | 2021 |
| Description | Speaker, Champalimaud Research Symposium, Lisbon Portugal (virtual) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | October 2022 Speaker, Champalimaud Research Symposium, Lisbon Portugal (virtual) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Speaker, Danish Association of Cancer Research, Copenhagen, - Jeff Pollard |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | May 2021 Speaker, Danish Association of Cancer Research, Copenhagen, |
| Year(s) Of Engagement Activity | 2021 |
| Description | Speaker, Edinburgh Breast Cancer special virtual symposium, - Jeff Pollard |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | February 2021 Speaker, Edinburgh Breast Cancer special virtual symposium, Edinburgh UK |
| Year(s) Of Engagement Activity | 2021 |
| Description | Speaker, ISREC SCC Symposium 2018, Lausanne, Switzerland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Topics covered included all of the hallmarks of cancer, with a focus on tumor immunology and mechanism guided therapies. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Speaker, Tumour Immunology and Immunotherapy symposium, Leuven, Belgium - Jeff Pollard |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | October 2021 Speaker, Tumour Immunology and Immunotherapy symposium, Leuven, Belgium |
| Year(s) Of Engagement Activity | 2021 |
| Description | Speaker, VIB Macrophage Symposium, Vrije University, Brussels |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Bringing together leaders in the macrophage field as well as pioneers of novel single-cell technologies. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Speaker, the Myeloid Network, Virtual presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | May 2022 Speaker, the Myeloid Network, Virtual presentation |
| Year(s) Of Engagement Activity | 2022 |
| Description | Sperm grown in lab |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Professor Sharpe offered a quote through Science Media Centre on this particular study. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.telegraph.co.uk/news/science/science-news/12173317/Sperm-grown-in-lab-could-allow-inferti... |
| Description | St Andrews Cancer Colloquium, UK |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A group of top cancer researchers and clinical oncologists from the USA, Italy, Canada and the UK took part in The Cancer Colloquium, hosted by the University's School of Medicine. |
| Year(s) Of Engagement Activity | 2017 |
| Description | St Andrews Day Thank you to all CRUK supporters in Scotland |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | CRUK in Scotland and Prof Pollard also filmed a special thank you on St Andrew's Day to 'the extraordinary generosity' of those who have supported their research and have helped make a significant difference to the survival of cancer patients. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://twitter.com/CRUKScotland/status/1200714334554525697/video/1 |
| Description | Stress & Inflammation in Tumor Progression & Metastasis conference, Weizman Institute, Israel |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | On 13 May, Jeff Pollard gave a talk called "Macrophages; Bad actors in human and mouse cancer" at the Stress & Inflammation in Tumor Progression & Metastasis conference at the Weizman Institute in Israel. Globally, the Institute is one of the highest ranking multidisciplinary scientific research institutes. It also educates much of Israel's scientific leadership and involved in science literacy public engagement activities with schools and the general public. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Stress & Inflammation in Tumor Progression & Metastasis, Weizman Institute, Israel |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Jeff Pollard gave a talk at the Stress & Inflammation in Tumor Progression & Metastasis conference at the Weizman Institute in Israel. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Sun Yat-Sen Memorial Hall, Japan |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Macrophage maleficence in cancer |
| Year(s) Of Engagement Activity | 2017 |
| Description | Sunlight study from Sarah Stock and colleagues |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A new study from Sarah Stock and Tommy's Centre for Maternal and Fetal Health suggests that getting more sunlight while pregnant can reduce the chance of placenta problems associated with premature birth and baby loss. Here are some links to coverage, appearing on 25.08.21 CRH, Daily Mail, Times and Star, STV news Sarah's comments on paracetamol use during pregnancy also received media attention in September 2021, including MSN, The Telegraph and The Times. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dailymail.co.uk/sciencetech/article-9922611/Sunshine-reduce-risk-premature-birth-study-c... |
| Description | Tea and Just talk, The Royal Society of Edinburgh, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Varsha Jain and Hilary Critchley held an open discussion about menstruation, highlighting their research focus on enhancing understanding of this area. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Telemedicine Abortion - editorial in the BMJ |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Ahead of the vote in the Commons on 30.03.22 to make a decision to approve home abortions in England (for pregnancies of 12 weeks or less) CRH's John Reynolds-Wright and Sharon Cameron created an impactful editorial for the BMJ. The World Health Organization's guidelines on abortion care recommend that medical abortion in the first 12 weeks of pregnancy can be safely delivered by telemedicine and that women can self-administer both mifepristone and misoprostol at home. John Reynolds-Wright, Sharon Cameron and colleagues at MRC CRH believe it is common sense to keep this as an option for women, emphasising that telemedicine abortion care is backed up by evidence based clinical guidance and expert advice. |
| Year(s) Of Engagement Activity | 2022 |
| Description | The 38th Annual Meeting of ESHRE took place in Milan from 3-6 July 2022. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Richard Anderson presented on motherhood after cancer, revealing reassuring findings that having a baby after having breast cancer doesn't negatively impact a women's chance of surviving the disease. Rod Mitchell was due to chair Session 82 on 06.07.22 which was entitled 'Digging into fertility preservation' (Session Type: selected oral communication) but flight problems made this impossible. He hopes to be involved next year! Rod was scheduled to take part in the 'Speed Dating' activity, which is an initiative hosted by the ESHRE Journal Club. This interesting concept involved participants forming pairs and spending 4 minutes sharing and collect information from each other including work place, profession, research fields, skills, and Twitter handle. After a 4 minutes slot, you switched partners and repeated the process. Participants met and exchanged network information with up to 7 ESHRE attendees |
| Year(s) Of Engagement Activity | 2022 |
| Description | The Association of Early Pregnancy Unit's Annual Scientific Meeting in Bristol (17 & 18 November) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Mike Rimmer gave a talk discussing COVID-19 vaccines and miscarriage (pictured). Andrew Horne gave an update on the GEM3 trial and lessons learned. Colin Duncan, Andrew Horne and Lisa Stars also chaired sessions at the meeting. Also in attendance: Medical and nursing staff from the Early Pregnancy Unit based at the Royal Infirmary of Edinburgh. |
| Year(s) Of Engagement Activity | 2022 |
| Description | The Champalimaud Research Symposium, which is the main scientific meeting of the Champalimaud Research, |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Jeff was also invited to speak in Lisbon at The Champalimaud Research Symposium, which is the main scientific meeting of the Champalimaud Research, gathering worldwide researchers across disciplines to discuss ongoing and cutting-edge research in the fields of physiology and cancer, and neuroscience since 2017. The edition of 2022 was the third in the Physiology and Cancer series, which was held in October and focussed on Tumor Microenvironment. |
| Year(s) Of Engagement Activity | 2022 |
| Description | The Countess of Wessex addresses 'hidden' women's health issues and speaks to CRH's Varsha Jain |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The Countess of Wessex discusses menopause, periods and pregnancy care in conversation celebrating her appointment as Patron of Wellbeing of Women "Hidden" women's health issues such as period problems and the menopause must be brought "out into the open" and talking about them normalised, Her Royal Highness The Countess of Wessex has said. In a video conversation celebrating her new patronage of women's health charity, Wellbeing of Women, Her Royal Highness said "it's about time we really had a grown-up conversation" about women's health and "don't allow it to be in the in the shadows anymore". During the conversation, The Countess spoke to Wellbeing of Women researchers including Varsha Jain. Her project - investigating heavy menstrual bleeding - is funded by the charity. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=slg3OrUS1ak |
| Description | The Edinburgh Obstetrics Society meeting and the XV Sofia Symposium of Infertility and Reproductive Health, Sofia, Bulgaria - Michael Rimmer |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Mike Rimmer presented at The Edinburgh Obstetrics Society meeting and the XV Sofia Symposium of Infertility and Reproductive Health, Sofia, Bulgaria. |
| Year(s) Of Engagement Activity | 2021 |
| Description | The HPV Research group, in partnership with the Dept of Pathology, |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The HPV Research group, in partnership with the Dept of Pathology, are working on a systematic review to assess the performance of circulating tumour/HPV DNA for diagnosis and longitudinal management of HPV associated anogenital cancers. This work will be presented at the Manchester Pathology meeting 2021 The HPV Research Group have supported the creation of HPV positive and negative control material to support validation of new HPV technologies. They are currently in discussion with External Quality Assurance providers to determine whether these can be integrated within their programmes. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.ed.ac.uk/shine |
| Description | The Human Papillomavirus (HPV) Research Group, 19th Scottish HPV Investigators Network, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Tim Palmer presented his data in the 19th Scottish HPV Investigators Network, showing a reduction in precancerous disease in women attending for their second screen, even when their first smear was abnormal, and for the first-time evidence that the number of cancers in immunised women is lower. Dr Kevin Pollock also presented in the event about HPV vaccine hesitancy, particularly about while uptake of vaccine has been over 80% in Scotland since 2008, there is no room for complacency. Other countries have been "hit" by anti-HPV vaccine messages (including on social media) which can have a significant and rapid impact on the vaccination programme as a consequence of perceived safety issues (e.g. Japan's coverage dropped from 70% to 1%, Ireland's from 80% to 50%). |
| Year(s) Of Engagement Activity | 2019 |
| Description | The Jennifer Brown Research Laboratory celebrates 15 years of saving lives |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Sir John Savill welcomed guests and we celebrated past achievements during presentations from Sarah and Gordon Brown, and Professor Andrew Calder and Dr Ian Laing who were founder members of the JBRL. Dr James Boardman, scientific director of the JBRL, gave a presentation about current and future work of the laboratory and the Theirworld Edinburgh Birth Cohort (TEBC), which is a new initiative designed to improve life course outcome after perinatal brain injury caused by preterm birth and / or sub-optimal growth in utero. The TEBC places patients at the centre of a research journey that encompasses medicine, imaging, biology, education and socio-economics, to deliver new understanding of, and accelerate the translation of treatment for, perinatal brain injury. We were honoured to listen to the parent perspective given by Catherine Smith, daughter of the late Labour leader John Smith. Catherine delivered her baby daughter at 28 weeks' gestation and she gave powerful testimony to the importance of perinatal research for driving improvements in care. We were delighted to be joined by family participants in our research, and by senior members of the University's academic community who represent a diverse field of expertise, thereby reflecting the interdisciplinary nature of the work of the JBRL. |
| Year(s) Of Engagement Activity | 2016 |
| Description | The MRC's Festival of Medical Research, Edinburgh |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Students from both Portobello High and Preston Lodge High School toured around the MRC centre. Rod Mitchell introduced the group to the Centre's latest research in fertility preservation. Students were also assisted throughout the day with activities and their questions answered by many of the Centre's talented research fellows and PhD students |
| Year(s) Of Engagement Activity | 2019 |
| Description | The Progress Educational Trust, in partnership with the Scottish Government, - Rod Mitchell |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The Progress Educational Trust, in partnership with the Scottish Government, is currently running the following reproductive health events, involving a number of CRH researchers and associates: 'Advances in Assisted Reproduction: What Can We Expect?' This took place on Wednesday 6 October 2021. The presentations were enlightening and the combined speakers gave an excellent overview of how fertility preservation and assisted reproduction has progressed to the point we are at now. The session ended with a lively Q&A. Speakers included, Evelyn Telfer, Adele Marston, Richard Anderson, Colin Duncan |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://pet.secure.force.com/PETEvents/PETEvent_Overview?id=a2g4J000000tGeh |
| Description | The Scottish Sun Online launches endometriosis awareness campaign Endo Period Stigma |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Andrew Horne was featured on the The Sun campaign to encourage employers to support employees with endometriosis. |
| Year(s) Of Engagement Activity | 2019 |
| Description | The Sun, United Kingdom |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Philippa Saunders was invited to talk to The Sun about endometriosis. |
| Year(s) Of Engagement Activity | 2019 |
| Description | The World Endometriosis Society's 15th World Congress on Endometriosis (WCE2023) - Andrew Horne |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The World Endometriosis Society's 15th World Congress on Endometriosis (WCE2023) arrives in UK for first time since 2000 1,200 delegates expected to attend, with economic impact for Edinburgh estimated at £3m Bid was led by the CRH's Andrew Horne and CIR's Philippa Saunders Endometriosis affects 190 million women worldwide and is one of the most common causes of pelvic pain and infertility The 15th World Congress on Endometriosis (WCE2023) will take place between 3-6 May, 2023. Endometriosis is listed by the NHS as one of the 20 most painful diseases and carries a significant personal and socio-economic burden. Those with endometriosis experience an average diagnostic delay of eight years and are often, during the life course of the disease, subjected to multiple hit-and-miss treatments with a variety of efficacy and side-effects. Andrew Horne said: "Being chosen to host WCE2023 is a recognition of the progress in endometriosis discovery that has come out of our excellent team from the MRC Centre for Reproductive Health and Centre for Inflammation Research. We are hugely excited to be hosting WCE2023 in Edinburgh: a unique congress that will bring together clinicians, scientists, and patient advocates from across the world towards the common goal of positively impacting the health and wellbeing of all with endometriosis and adenomyosis." Press articles highlighting the Congress be accessed below: |
| Year(s) Of Engagement Activity | 2021 |
| Description | Therapy to stop premature birth safe but ineffective, study finds |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A therapy widely recommended in the UK, Europe and the US to stop babies from being born too soon is ineffective, research shows. The treatment does not appear to pose any harm to mother or baby but has no effect on preventing an early birth, the findings reveal. Researchers say that use of the medicine should be reviewed. They also call for a re-doubling of efforts to find alternative interventions to prevent premature births. Previous research suggested that the therapy - a hormone called progesterone - may stop pregnant women from giving birth early but little was known about its long term effects. This latest trial - involving more than 1200 women - is the largest to assess the effects of the treatment on women and the first to study its effects in babies born after the therapy. Researchers focused on women who are considered to have a greater risk of premature delivery - either because they have previously delivered a baby early or have lost a baby late in pregnancy. Around a half of the women were given progesterone and the others were given a dummy pill. The team found that whilst the therapy appeared to be safe, it did not reduce the risk of premature delivery and offered no notable health benefits for mother or baby. More than 64 hospitals from around the UK were involved in the research, which was led by the Tommy's Centre for Maternal and Fetal Health at the University of Edinburgh. The study is published in The Lancet. It was funded by the Efficacy and Mechanism Evaluation (EME) Programme, a partnership between the Medical Research Council and National Institute for Health Research. Professor Jane Norman, Director of the Tommy's Centre for Maternal and Fetal Health at the University of Edinburgh, said: "Babies born too early have a much greater risk of short-term and long-term health problems. We need to find new strategies that help mums carry their babies to term." |
| Year(s) Of Engagement Activity | 2016 |
| Description | Tommy Sheppard visit to CRH (part of parliamentary scheme) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Part of parliamentary scheme |
| Year(s) Of Engagement Activity | 2017 |
| Description | Tortoise: The Slow Newscast podcast |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Richard Anderson featured in this Tortoise: The Slow Newscast podcast episode entitled 'The missing male pill', which discusses the male attitude to contraception. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Translation UK 2022 in Sheffield from 29.06.22 - 01.07.22. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Triin Õunapuu (Gray lab PhD student) and Bee Nagy (lab technician) attended Translation UK 2022 in Sheffield from 29.06.22 - 01.07.22. Triin gave presented "A sexually dimorphic cardiovascular /haemodynamic phenotype in Pabp4-/- mice - getting to the heart of the story" and Bee showcased her poster entitled "A functional analysis of mutations in DAZL identified in patients with impaired fertility". |
| Year(s) Of Engagement Activity | 2022 |
| Description | Tumour Immunology and Immunotherapy symposium - Jeff Pollard |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Jeff Pollard gave "in person" conference invited talks to the Tumour Immunology and Immunotherapy symposium, in Leuven, Belgium and the BSI in Edinburgh. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Tumour Infiltrating Myeloid Cell Compartment Symposium, Leiden University |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Keynote speaker : Tumour associated macrophages: from mechanism to therapy |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.timcc.eu/?page_id=629 |
| Description | UK Extracellular Vesicle Forum in Edinburgh. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Mike Rimmer presented a poster at the UK Extracellular Vesicle Forum in Edinburgh. He also organised and chaired an Early Career Researcher Session (Norah Spears was an invited speaker at this session). Sharon Cameron and Michelle Cooper (and Kirsten Black from the University of Sydney) were successful with a collaborative University of Sydney/University of Edinburgh grant which will permit a research exchange and establish an International Consortium for Postpartum Contraception (ICPP). Michelle Cooper was awarded the David Bromham Seed Research Fund from The Faculty of Sexual and Reproductive Health UK to establish a UK menopause research network. |
| Year(s) Of Engagement Activity | 2022 |
| Description | University of Edinburgh Neuroscience Day, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Irene Molina and Amy Lloyd presented posters at University of Edinburgh Neuroscience Day on their work on brain repair. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Vaccines ruled out in neonatal deaths spike |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Sarah provided expert commentary in the Herald in October 2022, concluding that "there was no "plausible" link between the unusually high levels of mortality among newborns in September last year and March this year to justify investigating maternal vaccination status". More information is available within this link. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Vagina Museum - Varsha Jain |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Varsha Jain has recorded a podcast for the Vagina Museum. With 120k followers on Twitter, the Vagina Museum is an immensely popular platform which discusses and raises awareness of women's health topics. This podcast is due to air in March 2022 - watch this space. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Varsha Jain was a panelist in the popular Wellbeing of Women event called 'Let's Talk Periods: Fibroids and Adenomyosis |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Varsha Jain was a panelist in the popular Wellbeing of Women event called 'Let's Talk Periods: Fibroids and Adenomyosis - 168 people attended this event |
| Year(s) Of Engagement Activity | 2022 |
| Description | Video Pregnant and obese: The clinic trying to help, BBC Breakfast News |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Fiona Denison and her maternal health team were featured on BBC Breakfast showcasing the multidisciplinary care they offer to women carrying too much weight during pregnancy. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Wearable technology could improve future healthcare - Andrew Horne |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Wearable technology could improve future healthcare Andrew Horne hopes that innovative wearable technology will improve treatment options for endometriosis. Read The Scotsman piece and RSE blog post to find out more. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.scotsman.com/news/opinion/columnists/endometriosis-how-wearable-technology-could-improve... |
| Description | Weizmann Institute of Science Life Sciences Colloquium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Macrophage Maleficence in Cancer |
| Year(s) Of Engagement Activity | 2018 |
| Description | Wellbeing of Women webinar on endometriosis, - Andrew Horne |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Andrew Horne delivered a Wellbeing of Women webinar on endometriosis, and he discussed the possibility that surgery for endometriosis could actually be worsening symptoms in an article in the Guardian (02.07.21). |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.theguardian.com/australia-news/2021/jul/02/a-common-treatment-for-endometriosis-could-ac... |
| Description | Wellcome Researcher's meeting : Molecular Mechanisms, Immunology and Parasitology |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Speaker |
| Year(s) Of Engagement Activity | 2016 |
| Description | Wellcome researchers' "Physiology and Cell Biology", Hinxton, Cambridge |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Jeff Pollard presented at the Wellcome researchers' "Physiology and Cell Biology" meeting in Hinxton, Cambridge. |
| Year(s) Of Engagement Activity | 2019 |
| Description | When will male birth contol be available? |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | John Reynolds-Wright provided expert commentary to this article on the future of male contraception, in The Washington Post. When will male birth contol be available? |
| Year(s) Of Engagement Activity | 2022 |
| Description | Women in Science in Scotland, The Royal Society of Edinburgh, Edinburgh |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Prof Hilary Critchley is interviewed and featured on 'The Women in Science in Scotland' exhibition. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Workshop Co-Chair/Speaker Tumor Myeloid-Directed Therapies Summit, Boston-Virtual |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | June 2022 Workshop Co-Chair/Speaker Tumor Myeloid-Directed Therapies Summit, Boston-Virtual |
| Year(s) Of Engagement Activity | 2022 |
| Description | World Endometriosis Society's 'Endometriosis and Adenomyosis Unlocked hybrid symposium' Andrew Horne |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Andrew Horne was delighted to be invited to speak at the World Endometriosis Society's 'Endometriosis and Adenomyosis Unlocked hybrid symposium' (27-28 May) on 'Engaging patients in research'. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Young Academy of Scotland (YAS) and Global Science Show June showcase. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Jackie Maybin appeared on the Young Academy of Scotland (YAS) and Global Science Show June showcase. This monthly showcase focused on the work of YAS members including Jackie. She spoke about menstrual health, problem periods and her research at CRH. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Young scientists from Liberton take part in CRH workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Ginnie Clark, Rocio Martinez Aguilar (Maybin lab), Francesca Hearn-Yeates (Horne lab) and Grace Forsyth (Mitchell lab) visited Liberton High School on 27.09.22 to offer students the chance to take part in a reproductive health themed scientific workshop. |
| Year(s) Of Engagement Activity | 2022 |
| Description | annual Neonatal Update, an international meeting of scientists and clinicians: 'Preterm birth and neurodevelopment: James Boardman |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | James Boardman gave invited lectures to the annual Neonatal Update, an international meeting of scientists and clinicians: 'Preterm birth and neurodevelopment: not just a matter of brain injury' and to the Newborn Brain Society. |
| Year(s) Of Engagement Activity | 2021 |
| Description | hormone-hijacking chemicals are to blame for declining sperm counts, Rod Mitchell |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Rod Mitchell features in this fascinating podcast, discussing whether hormone-hijacking chemicals are to blame for declining sperm counts, how concerned we should really be, and whether there's anything we can do about it. |
| Year(s) Of Engagement Activity | 2021 |
| Description | invited presentation at Gordon Research Seminar: Glia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Irene Molina, a final year PhD student, presented her work on astrocytes and brain repair as an invited oral presentation at the Gordon Research Seminar: Glia, and as a poster at the Gordon Research Conference. |
| Year(s) Of Engagement Activity | 2019 |
| Description | joint European Neonatal Societies Congress - James Boardman |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | James Boardman gave an invited lecture at the joint European Neonatal Societies Congress in September titled 'Atypical cognition in preterm infants detected using eye-tracking'. He also chaired sessions at the Congress. |
| Year(s) Of Engagement Activity | 2021 |