MICA: Tackling iatrogenic Cushing's syndrome through 11beta-HSD1 inhibition

Lead Research Organisation: University of Oxford
Department Name: RDM OCDEM


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Description MRC programme
Amount £1,445,000 (GBP)
Funding ID MR/P011462/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 04/2017 
End 03/2022
Description AstraZeneca 
Organisation AstraZeneca
Country United Kingdom 
Sector Private 
PI Contribution We conducted and completed the clinical study funded by the grant including the acquisition and analysis of the clinical samples.
Collaborator Contribution The contribution in kind is the provision of the active drug and placebo for the clinical study fundede by the grant. The financial contribution is to fund the RNA-sequencing analysis of the adipose and muscle biopsies pre and post intervention.
Impact Abstract submitted to European congress of endocrinology 2020. Full manuscript in preparation
Start Year 2017
Description Public engagement talk - Malvern college, Worcestershire 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Presentation to pupils and staff and informal discussions about research
Year(s) Of Engagement Activity 2017