Protecting Women from Economic shocks to fight HIV in Africa (POWER)

Lead Research Organisation: University College London
Department Name: Institute for Global Health

Abstract

HIV/AIDS is one of the leading cause of mortality globally and the leading cause among women aged 15-44 years. African women aged 15-24 are twice more likely to be infected with HIV than their male counterparts. In Cameroon, one of the countries with the highest gender disparity in HIV globally, adolescent girls are five times more likely to be infected with HIV than boys of the same age. There is a growing number of studies showing that risks taken during transactional sex and commercial sex -in addition to biological susceptibility- are responsible for gender inequalities in HIV/AIDS. However, there is superficial understanding of the main causes driving risky sexual behaviours of women who engage in those practises in Africa.

Recent studies have shown that women mainly adopt risky sexual behaviours in order to cope with negative income shocks (e.g. agricultural and climatic shocks, illness or death of family members) and suggest that economic shocks are a substantial piece of the HIV puzzle in Africa. If women adopt risky sexual behaviours to cope with negative income shocks, hence providing women formal risk-coping strategies could be a very promising approach to prevent HIV. However, there are still important gaps in knowledge, mainly because no previous study has been designed to specifically answer this research question.

The goal of this research is to fill these gaps in knowledge in order to inform the design of novel public health interventions to tackle sexually transmitted infections (STIs) and HIV. Specifically, the study aims (1) to estimate the effect of economic shocks affecting households on sexual behaviours and STI and HIV acquisition of young women, (2) to identify the channels through which economic shocks affect STIs and HIV, (3) to estimate the effectiveness of health insurance as a strategy to protect women from economic shocks in order to prevent STI and HIV and (4) to measure the cost-effectiveness of an intervention that protects women from economic shocks to prevent HIV in the general population.

The proposed study will follow a new cohort of women in Cameroon. The study will recruit 1,500 unmarried adolescent girls and young women engaging in transactional sex or commercial sex. Over a 1-year period, the study will collect three biobehavioural and socioeconomic surveys as well as weekly sexual diaries (n=78,000). A randomised controlled trial will be embedded to the cohort study and will provide women allocated to the treatment group with a formal risk-coping strategy (a family health insurance).

This research is of immediate necessity to address a vital public health challenge of our time and has the strong potential to have a long lasting impact on shaping the research agenda on HIV/AIDS.

Planned Impact

The research proposal has a number of beneficiaries:

The research team: The PI will gain further knowledge, skills and experience to evolve from a early career researcher to independent researcher leader. Research Fellows will gain postdoctoral experience through formal training and fieldwork experience.

LSHTM: LSHTM will benefit from this research through a more diversified research portfolio, and high-quality research outputs in a strategically important area of public health research.

Academic beneficiaries: The research will introduce novel insights on the driver and solutions to reduce risky behaviours of a group at high-risk of HIV in Africa.

Ministry of health of Cameroon and technical and financial partners: The project aims to provide evidence-based answers that help in designing policies to change risky behaviours of women at risk of HIV in Cameroon. Policy briefs will include clearly written policy suggestions that will benefit the Ministry of Health and technical and financial partners.

Civil society organisations working with young women who engage in transactional or commercial sex in Cameroon could be impacted by the research by exploring a new strategy to prevent HIV among this group.

Adolescent girls and young women: Ultimately the beneficiaries of this research are the people whose health and life quality can be improved by effective policies tackling the spread of STI and HIV/AIDS in Cameroon. This includes adolescent girls and young women who engage in transactional sex, female sex workers, their sexual network as well as their family members.

Publications

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Lépine A (2020) Risk aversion and HIV/AIDS: Evidence from Senegalese female sex workers in Social Science & Medicine

 
Description Background: Young women in Sub-Saharan Africa are disproportionately affected by the HIV epidemic: they are twice as likely to be living with HIV than men of the same age and account for 64% of new HIV infections among young people. Many studies suggest that financial needs, alongside biological susceptibility, are the main causes of the gender disparity in HIV acquisition. While the literature shows limited understanding of the link between poverty and HIV, there is some new robust evidence demonstrating that women adopt risky sexual behaviours as a way to cope with economic shocks.

Method: We recruited 1,506 adolescent girls and young women engaging in transactional or commercial sex in Yaounde, Cameroon using respondent driven sampling women. Half of women were randomly selected to receive free health insurance for themselves and their economic dependents over 12 months. We followed women over this period and collected behavioural data as well as sexually transmitted infections and HIV biomarkers.

Results: We find that study participants engaging in transactional sex allocated to the treatment group were less likely to be infected with HIV by 3.1 percentage points ( p-value<0.01), corresponding to a 88% decrease in HIV infections. We show that this impact is explained by a reduction in health shocks that led to a decrease in risky sexual behaviours. Precisely, we show that treated participants were more likely to stop transactional sex as the result of the intervention. In addition, we show that for those remaining in transactional sex, the intervention led to an increase in condom use by 15 percentage points. However, due to low HIV incidence among sex workers, there was no evidence of a reduction of HIV incidence among this group.

Conclusion: The study provides the first evidence of the effectiveness of formal shock-coping strategy against HIV risk. We estimate that in our trial, the cost for each HIV infection averted is US$5,638 among the cohort of women engaging in transactional sex. Policymakers should consider formal shock-coping strategies to prevent HIV among women in Africa.
Exploitation Route Submitted UKRI FLF to maximise research impact.
Sectors Healthcare

URL https://sites.google.com/site/aurelialepine/Home/ukri-future-leaders-fellowship
 
Title POWER baseline data set 
Description Biobehavioural survey on 1506 women 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
Impact Currently used for data analysis 
 
Title POWER endline data set 
Description Biobehavioural survey collected 12 month after the start of the intervention 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
Impact Data currently used. 
 
Title POWER midline data set 
Description Biobehavioural survey 6 months after the start of the intervention 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
Impact Data currently used for analysis 
 
Title POWER randomisation data set 
Description Randomisation of POWER study participants 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
Impact Currently used for data analysis 
 
Description Presentation at the Centre for Health Economics at the University of York 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Internal seminar at the Centre for health economics at the University of York
Year(s) Of Engagement Activity 2022
URL https://www.york.ac.uk/che/seminars/che/2022-seminars/aurelia-lepine/
 
Description Video 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Video
Year(s) Of Engagement Activity 2020
URL https://www.youtube.com/watch?v=DzrzEI_N9Rk&feature=youtu.be