Contextual Awareness, Response and Evaluation: Diabetes in Ghana

Lead Research Organisation: University College London
Department Name: Institute for Global Health

Abstract

Type 2 diabetes (T2D) affects approximately 6% of adults in Ghana resulting in poor mental and physical health, premature death, and increased costs for individuals, families and healthcare services. The CARE:Diabetes project represents a research collaboration between public health specialists, historians, social scientists, economists, political scientists, psychologists, pharmacists and engineers to understand the contextual drivers and consequences of T2D in three urban communities in Accra, Ghana. This will include research into the historical, political and physical context of T2D, giving us insights into how environmental, economic and social factors have shaped T2D risk in this urban setting. Information on individual, household and community burdens of disease and risk factors will be gathered through community surveys while social science methods will provide deep understanding of contextual determinants and perceptions of disease. Assessment of digital infrastructure and development capacity will identify opportunities for digital strategies to raise awareness of T2D, prevent disease, and strengthen health systems. We will also map available formal and informal health care providers and work with these, community groups and policy makers to co-create intervention strategies to reduce T2D risk in the study area. In particular, we will adapt and test a specific community mobilisation intervention that has proven successful in reducing diabetes risk in other settings.

Technical Summary

Ghana is a lower middle income country where type 2 diabetes (T2D) affects approximately 6% of adults and prevalence is increasing, resulting in poor mental and physical health, premature mortality, and increased costs for individuals, families and healthcare services. There is an urgent need for cost-effective T2D prevention programmes designed specifically for Ghanaian populations. Any such intervention must address the broad socio-cultural and economic determinants and consequences of T2D that include traditions and customs, gender norms, urbanisation, living conditions and housing arrangements, rural-urban migration cycles, health service provision and market forces and regulation.

We will conduct truly interdisciplinary research to understand the history, epidemiology, narratives, socio-ecological drivers, consequences and responses to T2D. We will use this contextual understanding to identify specific strategies and recommendations for intervention. This will include community, health system, market and policy level solutions and will recognise the emergent potential of appropriate digital interventions such as mHealth education and behaviour change, electronic decision support, and enhanced peer-to-peer communication and consultation systems.

Further, we will adapt and test a Participatory Learning and Action (PLA) community mobilisation intervention for T2D. The PLA intervention, proven to reduce T2D prevalence and risk in Bangladesh by over 60%, works by facilitating community discussion, mutual learning to raise critical consciousness and foster collective action to reducing disease risk in general populations. With appropriate contextual adaptation, we hypothesise that PLA community mobilisation has the potential for substantial impact on reducing the T2D burden in urban Ghana.

Planned Impact

Through a holistic, integrated approach to examining the contextual factors related to T2DM we will build awareness, tools and capacity to address the issues from a communities, systems, research and policy level.

The beneficiaries of the research will be:
- People with type two diabetes or at risk of developing type two diabetes and their families
- Health professionals
- Policymakers
- Civil society organizations
- Industry
- Researchers

Overall impact will be:
- Increased understanding of diabetes, healthy lifestyles and ways to address it within communities in Accra
- A better equipped health system to deal with T2DM and well-developed local models for community interventions
- At a policy and civil society level the profile of diabetes will be raised, and specific recommendations for an integrated approach to tackling T2DM available
- Increased capacity of researchers in the UK and Ghana through mutual learning

Publications

10 25 50
 
Description To date, we have achieved an enormous amount of transdisciplinary work to understand diabetes in the Ga-Mashie community, Accra, Ghana. Community engagement as well as engagement with policy and other stakeholders throughout the project have fostered a collaborative approach to the work and created opportunities for a wide range of actors to participate in and influence our research. Analysis and synthesis of findings from diverse academic disciplines, including history, digital, epidemiology, sociology, policy, urban design and GIS, economics and health systems have so far enabled us to describe the complexity of diabetes risk, lived experiences and response opportunities within the study context. We have shared these findings at an interactive workshop in London and have similar events planned for dissemination and discussion in Ghana.
Exploitation Route Yet to be realised - the project in ongoing.
Sectors Agriculture, Food and Drink,Communities and Social Services/Policy,Digital/Communication/Information Technologies (including Software),Environment,Healthcare

 
Description UCL Institutional Emergency Global Research Fund
Amount £29,057 (GBP)
Organisation University College London 
Sector Academic/University
Country United Kingdom
Start 05/2021 
End 07/2021
 
Description UKRI Covid-19 CoA funding
Amount £15,281 (GBP)
Funding ID 181573 
Organisation United Kingdom Research and Innovation 
Sector Public
Country United Kingdom
Start 01/2021 
End 09/2021
 
Description Nossal Institute for Global Health, University of Melbourne 
Organisation University of Melbourne
Country Australia 
Sector Academic/University 
PI Contribution Nossal Institute for Global Health, University of Melbourne are collaborators and co-investigators on the CARE Diabetes project.
Collaborator Contribution Nossal Institute for Global Health, University of Melbourne are collaborators and co-investigators on the CARE Diabetes project.
Impact This collaboration has led to protocol development and ethical approvals for CARE. As part of the wider CARE project the collaboration is multidisciplinary.
Start Year 2020
 
Description University of Ghana 
Organisation Noguchi Memorial Institute for Medical Research (NMRR)
Country Ghana 
Sector Academic/University 
PI Contribution Noguchi Memorial Institute for Medical Research are collaborators and co-investigators on our CARE Diabetes award.
Collaborator Contribution Noguchi Memorial Institute for Medical Research are collaborators and co-investigators on our CARE Diabetes award.
Impact This is a multidisciplinary colaboration, including the following: epidemiology; medicine; social sciences; urban planning; history; pharmacy; digital health
Start Year 2020
 
Description University of Greenwich 
Organisation University of Greenwich
Country United Kingdom 
Sector Academic/University 
PI Contribution University of Greenwich is a collaborating partner on our CARE Diabetes project.
Collaborator Contribution University of Greenwich is a collaborating partner on our CARE Diabetes project.
Impact This collaboration has led to the development of study protocols and ethical applications. As part of the wider CARE project this is a multi-disciplinary collaboration.
Start Year 2020
 
Description University of York 
Organisation University of York
Country United Kingdom 
Sector Academic/University 
PI Contribution In 2019 Dr Ed Fottrell joined the 'Improving Outcomes in Mental and Physical Multimorbidity and Developing Research Capacity (IMPACT) in South Asia' consortium led by the University of York. As part of this work DMagic partners joined the network and subsequently we have secured NIHR funding for work on diabetes and depression in Bangladesh and Pakistan.
Collaborator Contribution The Diabetic Association of Bangladesh joined this network and attended a workshop in York to develop a funding bid (as co-investigators) to develop and test an intervention for diabetes and depression in Bangladesh and Pakistan.
Impact This is a multidisciplinary collaboration that has so far resulted in secured funding for research activity that will begin in 2020.
Start Year 2019
 
Description 2021 Stakeholder Meeting, Accra 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Policymakers/politicians
Results and Impact This half day stakeholders' meeting was organised for relevant key stakeholders in the fight against the growing burden of diabetes around the following key objectives:
1. To formally inform stakeholders about the CARE project, planned activities, expected outcomes and expected roles of the stakeholders in the implementation of the project.
2. To provide the opportunity for the project team to elicit from stakeholders their views and contribution on the study design, proposed intervention and implementation of the project activities and how these could inform and impact the overall implementation of the project.

The meeting had in attendance representatives from the following national and community organisations and groups: Ministry of Health, Ghana Health Service NCD Control Programme, Food and Drugs Authority, Ghana NCD Alliance, Ghana Medical Association, Ghana Psychological Association, and community representations from Accra Metropolitan Authority, James Town Health Club, Ga Mashie Development Agency (GAMADA), Chief Fisherman and a Linguist from Ga Mashie, a market queen from Ga Mashie among others.
Year(s) Of Engagement Activity 2021
 
Description Community engagement event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact This was a community engagement event to formally introduce the CARE diabetes project to the two study communities, Jamestown and Usshertown (Ga Mashie). The meeting was intended to create a platform for dialogue between the researchers and study communities. The engagement was also intended to build synergies with the community and inculcate the sense of ownership of the project among the community from inception. To facilitate the community ownership process, we partnered with the Ga-Mashie Development Agency (GAMADA), an organisation tasked with the responsibility of leading development processes in the two communities that form Old Accra in organizing the programme. GAMADA provided the space and facilitated the platform to host the research team and the community.

Leaders of GAMADA welcomed the participants and introduced all the guests. This was followed by two presentations. The CARE Diabetes project was formally introduced to the community at this point by co-investigator Dr. Ernestina Dankyi. Participants were informed about the general nature of the research and how it would be carried out. They were informed that the research would involve questionnaire administration, interviews, rapid diagnostics using some amount of blood samples, pictures and others. There were also breakout sessions which created a platform to listen to community perspectives on Type-2 diabetes.
Year(s) Of Engagement Activity 2022
 
Description Ghana Policy Stakeholder Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact As part of the CARE project, we brought together policymakers and key stakeholders in the NCDs space, including healthcare professionals to discuss the rising burden of diabetes, understand the implementation of policies to tackle this and jointly agree on the next steps and key recommendations in reducing the high burden of diabetes. Though the focus was on diabetes, participants also placed emphasis on other chronic conditions such as hypertension. The event saw key presentations on the burden of diabetes globally, in Ghana and the study context /Ga-Mashie (urban poor Ghana). This was followed by another presentation on the WHO Best Buys to highlight to participants the global policy framework for the implementation of policies and interventions for NCDs care. Three major panel group discussions where we had different panels for healthcare professionals, people living with diabetes, and CSOs/NGOs/Media/Policy Makers.

Though this was meant to gather data on the implementation of policies and interventions for diabetes care, the activity created a platform for stakeholders to discuss the burden of diabetes and proffered solutions to the implementation challenges which would subsequently inform future implementation efforts. A representative of the Health Minister acknowledged the potential impactful nature of the CARE project and promised to ensure the recommendations are prioritized in national-level discussions to enhance overall NCDs policy implementation.
Year(s) Of Engagement Activity 2022
 
Description Health Inequalities in Diabetes Research Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Project PI, Edward Fottrell, was an invited participant at a Health Inequalities in Diabetes Research Workshop organised by Diabetes UK. This workshop brought together people with lived experience of diabetes, researchers and healthcare professionals to identify key research recommendations around health inequalities in diabetes. The two-day workshop sought to better understand how research can be used to reduce diabetes-related health inequalities, including for socially deprived and minority ethnic groups. A summary of the event and recommendations for future activity were published in Diabetic Medicine (https://onlinelibrary.wiley.com/doi/full/10.1111/dme.15024).

As a direct consequence of this workshop, UCL and Diabetes UK have organized a further workshop and round-table discussion to be held in March 2023 to explore cross-learning and knowledge exchange between global health diabetes research and UK-based diabetes research, with a focus on mixed-methods implementation science approaches.
Year(s) Of Engagement Activity 2022
URL https://onlinelibrary.wiley.com/doi/full/10.1111/dme.15024
 
Description Noguchi Memorial Institute for Medical Research Annual Conference 2022 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact The Noguchi Memorial Institute for Medical Research (NMIMR) of the University of Ghana, 2-Day Annual Research Meeting (ARM) on November 17-18, 2022. The theme of the research meeting was "Epidemics, Pandemics and Diseases of Public Health Importance: Bridging the Research - Policy Divide".

The organising committee asked for submissions that addressed a broad range of health science topics in the areas of communicable and non-communicable diseases and encouraged submissions on a range of research including health systems, implementation research and intervention research and the CARE Diabetes project fit in well with this criteria. We submitted an abstract and gave an oral presentation to staff at based at the NMIMR and external speakers including Dr Anarfi Asamoa-Baah, the coordinator of Ghana's COVID-19 response.
Year(s) Of Engagement Activity 2022
URL https://www.ug.edu.gh/events/nmimr-annual-research-meeting
 
Description UK Dissemination & Symposium 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact We held a public event in London to share the methods and preliminary findings from the CARE Diabetes project with a community of researchers, healthcare professionals, policy and civil society organisations. The event followed a four-day workshop of project team members in London and was an opportunity to showcase the broad range of methodological approaches and disciplines within the project.

Preliminary findings were discussed and the timing and nature of the event allowed for broad feedback and recommendations on future analyses and activities as we enter the final year of the project.
Year(s) Of Engagement Activity 2023