Unlocking potential: developing innovative adolescent screening visits for health promotion, prevention and treatment in low-resource settings
Lead Research Organisation:
London School of Hygiene and Tropical Medicine
Department Name: Epidemiology and Population Health
Abstract
In adolescence, health-related behaviours are adopted that will have substantial positive or negative impacts on the individual's short- and long-term health, educational attainment, and employment prospects. However, in most low-income countries few adolescents have any contact with health services, especially for health promotion and disease prevention, and services are not always appropriate for their needs. Due to resource constraints there is often limited capacity to provide high-quality youth-friendly health services. Technological advances provide opportunities to deliver services and information away from traditional clinical settings, hence reducing barriers such as cost or confidentiality. Adolescents may be particularly receptive to digital platforms that allow them to self-manage their health and well-being.
What is A-CHECK? The programme will screen and treat/refer adolescents for common conditions through health check-ups in younger (10-13y) and older (16-19y) adolescents. Adolescents will only be screened for conditions with an accurate and acceptable test and a locally accessible effective intervention e.g. mental health, HIV, vision and hearing, anaemia.
What exactly will be done? I will develop, pilot-test, implement and evaluate the innovative A-CHECK programme and an accompanying digital platform in Zimbabwe. Check-up visits will take place at schools for younger and in the community for older adolescents. The platform will reduce the workload of staff by allowing adolescents to self-screen using questionnaires (e.g. mental health, risk behaviours) and pre-existing apps (to test hearing, eyesight, body composition), and will help the team to keep in touch with adolescents and provide information on referral appointments. I will analyse the data collected through the A-CHECK programme to improve its future acceptability and cost-effectiveness.
What are the main outcomes? Answers to the following questions - Do adolescents attend the screening and referral appointments? What impact do visits have on their health and education? How much does it cost for an adolescent to be screened and to obtain the recommended care for a condition? Is this a good value for money?
What is innovative about this study? The approach is innovative and novel, because, few LMICs currently provide check-up visits for adolescents and in countries where they are provided, the visits don't always meet the needs of adolescents e.g. don't include mental health screening. This proposal takes the innovative and bold step of moving from condition-specific health programmes towards an adolescent-centred approach focusing on what matters most to adolescents. This is the first empirical study to have investigated the effectiveness and cost-effectiveness of multi-component adolescent health check-ups. Specific innovations:
- Youth Researchers will participate in a human-centred design approach to intervention development
- Digital platform on which adolescents will complete some of the health screening activities, saving consultation time and improving the quality and efficiency of data collection
- Novel adolescent engagement activities including crowdsourcing contests and a reward system in the digital platform with adolescents gaining points when they complete screening and/or attend referral visits
- Machine learning and innovative data analysis to maximise A-CHECK efficiency and engagement by providing targeted messages and services
Why Zimbabwe? Zimbabwe is an ideal location for A-CHECK with great potential for scale-up given the close collaboration between BRTI and the Ministries of Health and Education, the emphasis on prevention within the 2018 School Health Policy, and the absence of other good ways to screen and refer adolescents. In other African settings, there is considerable interest in adolescent check-ups and potential for the Zimbabwean model to be adapted elsewhere.
What is A-CHECK? The programme will screen and treat/refer adolescents for common conditions through health check-ups in younger (10-13y) and older (16-19y) adolescents. Adolescents will only be screened for conditions with an accurate and acceptable test and a locally accessible effective intervention e.g. mental health, HIV, vision and hearing, anaemia.
What exactly will be done? I will develop, pilot-test, implement and evaluate the innovative A-CHECK programme and an accompanying digital platform in Zimbabwe. Check-up visits will take place at schools for younger and in the community for older adolescents. The platform will reduce the workload of staff by allowing adolescents to self-screen using questionnaires (e.g. mental health, risk behaviours) and pre-existing apps (to test hearing, eyesight, body composition), and will help the team to keep in touch with adolescents and provide information on referral appointments. I will analyse the data collected through the A-CHECK programme to improve its future acceptability and cost-effectiveness.
What are the main outcomes? Answers to the following questions - Do adolescents attend the screening and referral appointments? What impact do visits have on their health and education? How much does it cost for an adolescent to be screened and to obtain the recommended care for a condition? Is this a good value for money?
What is innovative about this study? The approach is innovative and novel, because, few LMICs currently provide check-up visits for adolescents and in countries where they are provided, the visits don't always meet the needs of adolescents e.g. don't include mental health screening. This proposal takes the innovative and bold step of moving from condition-specific health programmes towards an adolescent-centred approach focusing on what matters most to adolescents. This is the first empirical study to have investigated the effectiveness and cost-effectiveness of multi-component adolescent health check-ups. Specific innovations:
- Youth Researchers will participate in a human-centred design approach to intervention development
- Digital platform on which adolescents will complete some of the health screening activities, saving consultation time and improving the quality and efficiency of data collection
- Novel adolescent engagement activities including crowdsourcing contests and a reward system in the digital platform with adolescents gaining points when they complete screening and/or attend referral visits
- Machine learning and innovative data analysis to maximise A-CHECK efficiency and engagement by providing targeted messages and services
Why Zimbabwe? Zimbabwe is an ideal location for A-CHECK with great potential for scale-up given the close collaboration between BRTI and the Ministries of Health and Education, the emphasis on prevention within the 2018 School Health Policy, and the absence of other good ways to screen and refer adolescents. In other African settings, there is considerable interest in adolescent check-ups and potential for the Zimbabwean model to be adapted elsewhere.
Planned Impact
Youth: The immediate benefit of this research will be adolescents living in Harare and Chitungwiza cities in Zimbabwe who participate in this study. They will benefit from health screening, health services/referrals, and increased information on how to improve their health and well-being. If A-CHECK is not an appropriate way of delivering health services for adolescents, then there will be limited immediate benefit of this research. However, the knowledge gained during the project will inform the improvement of the content and/or the implementation of youth friendly health services in this area. The small number of adolescents and young people who participate in our Youth Advisory Group will gain an understanding of research, and may benefit from an increased sense of empowerment. If A-CHECK is effective and scaled-up in Zimbabwe and/or implemented in other LMICs, then many more adolescents will benefit from improved health and educational outcomes.
Families and the wider local community: Any benefit for adolescents in terms of improved health and well-being may benefit their partners and families by improving trust and/or engagement with healthcare services, and by improving overall well-being in the family. Short-term community-wide benefits would be minimal but if the intervention were to be implemented on a larger scale (based on the results of this work) then we would anticipate economic and societal impacts because of a more effective public health service, and improved health, prosperity, and quality of life for adolescents and their families.
Primary health care providers: This research will benefit primary health care providers by engaging with adolescents who are slipping through the net of existing preventive and treatment services. In the longer-term the use of a digital platform as a tool to facilitate more efficient screening, treatment and referral may reduce the workload of clinic staff and increase overall efficiencies in the health service.
Policy makers/programmers: This study is designed to inform practice, and we anticipate that the findings will be used to inform the design and implementation of adolescent check-up visits. If effective, check-up visits can be used as a strategy to achieve the goals of the 2018 School Health Policy. The findings e.g. on integration of services, self-screening etc. may also be transferrable to other population groups. In addition to data on the acceptability, feasibility and impact of the A-CHECK intervention, we will also be able to provide policy makers/programmers with data on the marginal cost of this approach. This intervention, if effective, would contribute to the international and national goal of universal healthcare.
International public health community: This research is aligned with relevant international and national commitments on improving the uptake of promotive, preventive and curative health care by adolescents, and by exploring the use of digital interventions within programmes. The results will be of interest to other regions and countries who are considering implementing digital interventions to improve adolescent health. The findings will feed directly into WHO guidelines on check-up visits for adolescents.
Academics & other collaborative staff: There is a paucity of research data on adolescents worldwide, as informed consent requirements often deter researchers from including those <18 years of age. This research will advance our understanding of the acceptability and feasibility of check-up visits and digital interventions for adolescents in LMICS, and the feasibility of engaging and interacting through a digital platform including through the use of self-screening questionnaires and screening apps. The A-CHECK team in Zimbabwe, and the LSHTM-based postdoc will have several capacity building opportunities including a significant on-the-job training and mentoring, and the opportunity to present at international conferences.
Families and the wider local community: Any benefit for adolescents in terms of improved health and well-being may benefit their partners and families by improving trust and/or engagement with healthcare services, and by improving overall well-being in the family. Short-term community-wide benefits would be minimal but if the intervention were to be implemented on a larger scale (based on the results of this work) then we would anticipate economic and societal impacts because of a more effective public health service, and improved health, prosperity, and quality of life for adolescents and their families.
Primary health care providers: This research will benefit primary health care providers by engaging with adolescents who are slipping through the net of existing preventive and treatment services. In the longer-term the use of a digital platform as a tool to facilitate more efficient screening, treatment and referral may reduce the workload of clinic staff and increase overall efficiencies in the health service.
Policy makers/programmers: This study is designed to inform practice, and we anticipate that the findings will be used to inform the design and implementation of adolescent check-up visits. If effective, check-up visits can be used as a strategy to achieve the goals of the 2018 School Health Policy. The findings e.g. on integration of services, self-screening etc. may also be transferrable to other population groups. In addition to data on the acceptability, feasibility and impact of the A-CHECK intervention, we will also be able to provide policy makers/programmers with data on the marginal cost of this approach. This intervention, if effective, would contribute to the international and national goal of universal healthcare.
International public health community: This research is aligned with relevant international and national commitments on improving the uptake of promotive, preventive and curative health care by adolescents, and by exploring the use of digital interventions within programmes. The results will be of interest to other regions and countries who are considering implementing digital interventions to improve adolescent health. The findings will feed directly into WHO guidelines on check-up visits for adolescents.
Academics & other collaborative staff: There is a paucity of research data on adolescents worldwide, as informed consent requirements often deter researchers from including those <18 years of age. This research will advance our understanding of the acceptability and feasibility of check-up visits and digital interventions for adolescents in LMICS, and the feasibility of engaging and interacting through a digital platform including through the use of self-screening questionnaires and screening apps. The A-CHECK team in Zimbabwe, and the LSHTM-based postdoc will have several capacity building opportunities including a significant on-the-job training and mentoring, and the opportunity to present at international conferences.
Organisations
- London School of Hygiene and Tropical Medicine (Lead Research Organisation)
- Organization for Public Health Interventions and Development (Collaboration)
- World Health Organization (WHO) (Collaboration)
- National Institute for Medical Research, Tanzania (Collaboration)
- University of Ghana (Collaboration)
- Peek Vision (Project Partner)
- hearScreen (Project Partner)
- World Health Organization (Project Partner)
- Ministry of Health and Child Care (Project Partner)
- University of Zimbabwe (Project Partner)
- Ministry of Pri & Sec Education Zimbabwe (Project Partner)
People |
ORCID iD |
| Aoife Doyle (Principal Investigator / Fellow) |
Publications
Kpokiri E
(2024)
How to (or how not to) implement crowdsourcing for the development of health interventions: lessons learned from four African countries
in Health Policy and Planning
Martin K
(2024)
Factors Associated With the Use of Digital Technology Among Youth in Zimbabwe: Findings From a Cross-Sectional Population-Based Survey.
in Journal of medical Internet research
O'Connor C
(2024)
Changes in Adherence and Viral Load Suppression Among People with HIV in Manila: Outcomes of the Philippines Connect for Life Study.
in AIDS and behavior
| Title | UKRI FLF award video : Aoife Doyle |
| Description | This film describes Aoife Doyle and her team who conduct research on young people's health in Zimbabwe. Doyle implemented a crowdsourcing contest and hackathon with young people to design the intervention brand which engaged young people with Y-Check. She works closely with local partner organisations, BRTI and OPHID, to document good youth engagement practice, and to support public engagement skill building among young people and researchers. Aoife Doyle was the winner of the public engagement award at the UKRI FLF Impact Awards 2024. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2024 |
| Impact | The video which was commissioned by UKRI has been shared on social media and by 13 March had been viewed 81 times. We have used the video to share the youth engagement work conducted as part of the Y-Check study. |
| URL | https://www.youtube.com/watch?v=bbCqozFBSFI |
| Title | Y-Check information video |
| Description | Video co-produced with adolescents to introduce the Y-Check study to all stakeholders |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2024 |
| Impact | The video has been viewed online 352 times and has been used at various meetings with stakeholders and other Y-Check dissemination activities. The video has facilitated stakeholder understanding of this complex intervention study. |
| URL | https://www.youtube.com/watch?v=IFfFAzAjuuE |
| Description | Y-Check is a multi-country research study which aims to develop, implement and evaluate an adolescent health and wellbeing check-up visit intervention. We conducted a pilot study in Chitungwiza, Zimbabwe which was led by The Health Research Unit Zim (THRU ZIM) at the Biomedical Research and Training Institute (BRTI) in collaboration with the London School of Hygiene & Tropical Medicine (LSHTM), the World Health Organization (WHO), Geneva, and partners. We conducted a hybrid implementation-effectiveness study of Y-Check, a comprehensive adolescent health check-up intervention in Zimbabwe. Eligible participants were 10-19-year-olds attending primary school, secondary school or community venues. We used self-administered digital questionnaires, provider-led clinical tests, and nurse reviews to screen for 20 conditions/behaviours. We provided health promotion, on-site care and referral to relevant providers. From October 2022 to September 2023, 2097 adolescents were enrolled and 1843 (87.9%) followed-up at 6 months. The primary outcome of appropriate care and/or referral(s) for all identified issues was achieved for (1321/1865) 70.8% of participants (95%CI 68.7-72.9%). At follow-up, there were improvements in nutrition, health-related quality of life, self-esteem, behaviours and educational outcomes. The intervention was feasible and acceptable but access to referral services varied by condition. Y-Check cost USD47 per participant. Through Y-Check, we identified untreated conditions, successfully treated and linked adolescents to services, and had positive impacts on health and well-being. |
| Exploitation Route | The Y-Check study showed the feasibility of delivering health and wellbeing check-up visits in urban Zimbabwe and provided initial evidence on the effectiveness of check-ups on health, education and well-being outcomes. The implementation procedures and findings have fed directly into planning for similar Y-Check studies in Tanzania and Ghana under the leadership of WHO, Geneva and funded by Fondation Botnar. In 2025, UNICEF will implement adolescent check-up visit in Indonesia, Jamaica and Papau New Guinea for 2025 building directly on the experiences of Y-Check and adapting the Y-Check tools and procedures. |
| Sectors | Education Healthcare |
| Description | The research findings have led to an increased interest in adolescent check-up visits and UNICEF are planning to implement a similar check-up visit intervention in 3 countries in 2025. The Y-Check manual and tools have been shared with UNICEF and other interested groups. Y-Check findings have been presented to UN agencies globally and nationally through WHO and are feeding into detailed guidelines which WHO are developing for the implementation of adolescent well-care visits. |
| Sector | Healthcare |
| Description | Presentation of Y-Check study at the WHO Meeting of the Strategic and Technical Advisory Group of Experts (STAGE) on Maternal, Newborn, Child, and Adolescent Health and Nutrition (MNCAHN) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Presentation of Y-Check study at the WHO Meeting of the Strategic and Technical Advisory Group of Experts (STAGE) on Maternal, Newborn, Child, and Adolescent Health and Nutrition (MNCAHN) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Bloomsbury PhD studentship |
| Amount | £109,026 (GBP) |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2022 |
| End | 08/2025 |
| Description | UKRI FLF Renewal |
| Amount | £594,480 (GBP) |
| Funding ID | MR/Z000319/1 |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2025 |
| End | 04/2028 |
| Description | Y-Check: The Effectiveness and Cost-Effectiveness of Adolescent Health and Well-being Check-ups in Three African Cities |
| Amount | $3,558,564 (USD) |
| Funding ID | REG-21-001 |
| Organisation | Fondation Botnar |
| Sector | Charity/Non Profit |
| Country | Switzerland |
| Start | 01/2022 |
| End | 06/2024 |
| Description | Mwanza Intervention Trials Unit (MITU) |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | Mwanza Intervention Trials Unit (MITU) |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | MITU are a collaborator on the multi-country Y-Check study. We have provided technical support to the Tanzanian Y-Check study. |
| Collaborator Contribution | MITU colleagues have provided technical support for the development of Y-Check Zimbabwe study protocol and procedures. |
| Impact | MEMA kwa Vijana study publications. Y-Check study protocol and study tools. Publication of Y-Check study protocol in peer-reviewed journal. Joint investigator meeting in Harare, Zimbabwe in January 2023. |
| Start Year | 2014 |
| Description | OPHID The Organization for Public Health Interventions and Development |
| Organisation | Organization for Public Health Interventions and Development |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | OPHID in Zimbabawe are partners on the Zvatinoda research project. Karen Webb who works at OPHID is co-PI on this proposal and co-leads the overall study. Other OPHID staff who are investigators on the project are Diana Patel and Tinashe Chinyanga. OPHID in Zimbabwe led the technical development of the Y-Check app. |
| Collaborator Contribution | OPHID are led the implementation of Zvatinoda field activities and liaison with local, regional and national stakeholders. |
| Impact | Grant proposals Additional collaboration with SHM Foundation Multi-disciplinary: epidemiology, social science, implementation science. Peer reviewed publication of Zvatinoda study findings and presentation at HIV & Adolescence conference. Video and song created by the Zvatinoda Youth Advisory Panel. Members of the Zvatinoda Youth Advisory Panel have gone on to join the Y-Check Youth Advisory Group and to work on OPHIDs BOOST intervention. Y-Check application. |
| Start Year | 2019 |
| Description | University of Ghana |
| Organisation | University of Ghana |
| Country | Ghana |
| Sector | Academic/University |
| PI Contribution | University of Ghana are a collaborator on the WHO-led multi-country Y-Check study. We have provided technical support to the University of Ghana team. |
| Collaborator Contribution | The University of Ghana team have provided technical advice on the development of Y-Check Zimbabwe study protocols and procedures. |
| Impact | Study protocol and tools. Y-Check protocol published in peer reviewed journal. Joint investigator meeting in Harare, Zimbabwe in January 2023. Collaborative visit to University of Ghana in Accra and Cape Coast in December 2024. |
| Start Year | 2021 |
| Description | World Health Organization |
| Organisation | World Health Organization (WHO) |
| Country | Switzerland |
| Sector | Public |
| PI Contribution | The Y-Check Zimbabwe and LSHTM teams which I lead provide technical support to WHO who are leading the multi-country Y-Check study. |
| Collaborator Contribution | WHO, Geneva are leading the multi-country Y-Check study. The Y-Check study in Zimbabwe, which I lead, is co-funded by UKRI and Fondation Botnar (through a grant to WHO). WHO provide technical support for the Y-Check studies. |
| Impact | Study protocol and procedures. The Y-Check study protocol has been published in a peer reviewed journal. Joint presentations on Y-Check at STAGE and other UN agency meetings. Visit of Aoife Doyle to WHO, Geneva in January 2025 to discuss next phase Y-Check research proposal and a new collaborative project on well-being. |
| Start Year | 2021 |
| Title | Y-Check screening tool application |
| Description | The Y-Check screening tool app is being used in the Y-Check study in Zimbabwe to screen adolescents for health conditions and risk behaviours. The app facilitates data collection and the identification of adolescents who need further treatment, counselling and/or referral. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Impact | A demo of the application has been shared with collaborators planning Y-Check studies in Ghana and Tanzania and may be adapted for use in those settings. |
| Description | Presentation at International Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation of main Y-Check Zimbabwe findings at the World Congress of Epidemiology in Cape Town |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.wce2024.org/detailed-programme/# |
| Description | Project inception meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The Y-Check study inception meeting was held in Chitungwiza in November 2021. Attendees included the District Development Coordinator and the District Schools Inspector. Following introductions and a presentation on Y-Check, attendees were asked to discuss and provide feedback on the following (1) How the study schools and communities should be selected? (2) Are the proposed community engagement structures appropriate? |
| Year(s) Of Engagement Activity | 2021 |
| Description | Results validation workshop with teachers |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | In March 2024, a workshop was held in Chitungwiza with teachers from the 6 schools that took part in the Y-Check study. Parents who were members of the School Development Committees (SDC) were also in attendance. The Y-Check team shared initial findings from the study and sought feedback and comment from the teachers and parents. Attendees were then asked to break into small groups to discuss and propose recommendations based on the study findings. These recommendations then fed into final recommendations from the study. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Youth Advisory Group (Y-Check) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | A youth advisory group (YAG) was set up for the Y-Check study in Zimbabwe. The YAG meets regularly (approx. every quarter) and provides input on study procedures, interpretation of findings, and packaging and dissemination of information to the wider population of young people. |
| Year(s) Of Engagement Activity | 2021,2022,2023,2024 |
| Description | Zve Hutano Crowdsourcing competition |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | A crowdsourcing competition was held with young people living in a peri-urban area of Zimbabwe to to solicit new ideas, images or strategies from adolescents on how to brand and promote the Y-Check adolescent health and well-being check-up visit intervention. There were two categories (music and design). Participants, who are between the age of 10-19 years, submitted an entry of either a song or picture. Competition winners participated in a 'hackathon' to further develop the logo, messaging and song supported by a local music artist and a local design company. The competition increased the visibility of the new Y-Check competition and faciliated entry into the study communities. |
| Year(s) Of Engagement Activity | 2021 |