Fibroblast Heterogeneity, Plasticity and Functions in Pancreatic Cancer
Lead Research Organisation:
UNIVERSITY OF CAMBRIDGE
Department Name: Cancer Research UK Cambridge Institute
Abstract
Pancreatic cancer is highly lethal, with only 1 in 10 patients surviving 5 years after diagnosis. Drug resistance is one of the main reasons of pancreatic cancer lethality and is largely caused by non-cancerous components that constitute up to 90% of the overall tumour mass and substantially contribute to the progression of the disease. Among these components, fibroblasts are the most abundant cell population and have been shown to play diverse roles, promoting drug resistance and tumour growth, but also potentially restraining cancer progression. We recently showed that pancreatic cancer fibroblasts are comprised of distinct populations, which could explain their functional diversity and emphasises the need to design selective therapies. To identify new targetable vulnerabilities, we aim to understand how pancreatic cancer cells and distinct fibroblast populations interact and affect each other. Additionally, as fibroblasts also play key roles in inflammation, we aim to determine differences and similarities of these cells across normal, inflammatory and malignant states. To address these questions, we will use mouse models and three-dimensional co-cultures of fibroblasts and pancreatic cancer cells grown as organoids. In combination with these models, we will employ genetic and pharmacologic approaches to characterise the roles, dynamic nature and heterogeneity of fibroblasts during pancreatic cancer progression and in pancreatitis, which is a pathological condition of inflammation of the pancreas and a risk factor of pancreatic cancer. In particular, we will define the mechanisms through which different genetic profiles of pancreatic cancer cells affect the heterogeneity of surrounding fibroblasts. We will also dissect fibroblast functions in both pancreatic cancer and pancreatitis. To do this, we will develop novel approaches that will enable the genetic ablation of distinct fibroblast populations in new co-cultures and mouse models. Finally, we will determine how metabolic signatures of distinct fibroblast populations are regulated and affect disease progression. Our analysis will identify in what ways fibroblast populations differentially impact pancreatic cancer progression and pancreatitis and will reveal new vulnerabilities for therapeutic intervention. The emerging understanding that some phenotypes and functions of pancreatic cancer fibroblasts are shared among different cancer types and inflammatory conditions indicates that our findings could be applied to other malignancies and diseased states.
People |
ORCID iD |
Giulia Biffi (Principal Investigator / Fellow) |
Publications

Araos Henríquez J
(2022)
Tracing back to one of the origins of immune evasion in pancreatic cancer.
in Cancer cell

Ferrer M
(2023)
Cachexia: A systemic consequence of progressive, unresolved disease.
in Cell

Mucciolo G
(2024)
EGFR-activated myofibroblasts promote metastasis of pancreatic cancer
in Cancer Cell

Obacz J
(2024)
Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma.
in The European respiratory journal
Description | We have made significant progress over the last year. 1) We have found that a subset of non-cancerous cells in pancreatic cancer, called fibroblasts, that was previously thought to be only cancer-restraining, is also cancer-promoting. This work has been published. 2) We have found that pancreatic cancer cell with different mutations shape their surrounding microenvironment, and this alters therapy response. This work is being prepared for submission. 3) We have generated and validated new mouse models that enable to alter fibroblast composition. |
Exploitation Route | The novel models generated can be used to understand fibroblast biology in other malignancies, and inflammatory and normal states. The new datasets generated can be used to understand biology of other stromal cells, in addition to fibroblasts, in pancreatic cancer. Our results can guide future combinatorial approaches, and patient stratification for tailored therapies. |
Sectors | Healthcare |
Description | CANCAN |
Amount | £20,000,000 (GBP) |
Funding ID | Grand Challenge: NIH ref - 1OT2CA278669-01, CRUK CGCATF-2021/100027 |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start |
Description | Cambridge Cancer Centre Renewal - Pump Priming award |
Amount | £30,000 (GBP) |
Funding ID | (SWAH/144) RG86786 Sponsor Ref A23625 |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2020 |
End | 03/2022 |
Description | Designing novel strategies to target tumor-promoting functions of pancreatic cancer fibroblast subtypes |
Amount | $382,961 (USD) |
Organisation | Department of Defense |
Sector | Public |
Country | United States |
Start | 08/2022 |
End | 09/2025 |
Description | Exploring the role of vascular function on hypoxia dynamics in solid tumours |
Amount | £85,000 (GBP) |
Funding ID | Isaac/WT ISSF (SWAI/272) RG89305 Sponsor Ref 204845/Z/16/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 02/2021 |
End | 01/2023 |
Description | Future Leaders Academy |
Amount | £125,000 (GBP) |
Funding ID | PCUK FLA (SWAI/257) G102883 Sponsor Ref FLF_2021_05 |
Organisation | Pancreatic Cancer UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2021 |
End | 03/2025 |
Description | Cancer Grand Challenge CANCAN 2022 Cold Spring Harbor, NY, USA |
Organisation | Cancer Research UK Cambridge Institute |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Dr Biffi is in the Cachexia Team: Understand and reverse cachexia and declining performance status in cancer patients. |
Collaborator Contribution | Dr Marcus Goncalves, Weill Cornell, New York - Input: provides expertise on cancer-associated cachexia - Output: we provide PDAC fibroblast expertise Eileen White and Tobias Janowitz are the other co-leads of the CANCAN team |
Impact | N/A |
Start Year | 2022 |
Description | Cancer Grand Challenge CANCAN 2022 Cold Spring Harbor, NY, USA |
Organisation | National Institutes of Health (NIH) |
Department | National Cancer Institute (NCI) |
Country | United States |
Sector | Public |
PI Contribution | Dr Biffi is in the Cachexia Team: Understand and reverse cachexia and declining performance status in cancer patients. |
Collaborator Contribution | Dr Marcus Goncalves, Weill Cornell, New York - Input: provides expertise on cancer-associated cachexia - Output: we provide PDAC fibroblast expertise Eileen White and Tobias Janowitz are the other co-leads of the CANCAN team |
Impact | N/A |
Start Year | 2022 |
Description | Collaboration with Pedro Perez-Mancera |
Organisation | University of Liverpool |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Contributed with data analysis to a joint publication. |
Collaborator Contribution | Contributed with data gathering and analysis to a joint publication. |
Impact | joint publication to be submitted |
Start Year | 2021 |
Description | Collaboration with Vincenzo Corbo - MAPK study |
Organisation | University of Verona |
Country | Italy |
Sector | Academic/University |
PI Contribution | I contribute to the pre-print: Differential Activity of MAPK signalling Defines Fibroblast Subtypes in Pancreatic Cancer. this work has been published on BioRxiv in 2023 and is currently under revision at Nat Comm. |
Collaborator Contribution | They led this work. |
Impact | link to the pre-print: https://www.biorxiv.org/content/10.1101/2023.10.30.564752v1 the team is comprised of scientists and clinicians. |
Start Year | 2023 |
Description | Collaboration with Vincenzo Corbo - SMAD4 study |
Organisation | University of Verona |
Country | Italy |
Sector | Academic/University |
PI Contribution | We led this study. Eloise Lloyd is the first author. |
Collaborator Contribution | Vincenzo Corbo has a biobank of genotype-known human pancreatic cancer samples. Lisa Veghini in his lab has stained these samples and scanned them for analysis here in Cambridge. |
Impact | We are in the final stages of manuscript preparation. |
Start Year | 2023 |
Description | Pancreatic Cancer UK Future Leaders Academy |
Organisation | University of Cambridge |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Dr Tim Halim - Output: we provide PDAC fibroblast and organoid expertise Professor Jason Carroll - Output: we provide PDAC fibroblast expertise and our CAF-locked lines |
Collaborator Contribution | Dr Tim Halim - Input: provides expertise on pancreatitis |
Impact | N/A |
Start Year | 2021 |
Description | Abcam Early detection of pancreatic cancer webinar |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Dr Biffi is a co-organizer of this webinar : Early detection of hard-to-treat cancers, such as pancreatic cancer, is critical for improving overall survival. In this session, we will be discussing areas of greatest need, such as the most promising biomarkers, challenges for clinical adoption, and much more. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.abcam.com/webinars/translational-and-therapeutic-advances-in-oncology-and-epigenetics |
Description | CRICK Cancer Research Symposium, The Crick, London,UK |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | This year's Crick Cancer Research Symposium will consider multiple angles of cancer research and provide a forum for lively discussion. Leading researchers from Europe and the UK will present their latest research alongside numerous presentations from early career researchers selected from submitted abstracts. Panel discussions and poster sessions, including prizes, will encourage further interactions. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.crick.ac.uk/whats-on/crick-cancer-research-symposium-2022 |
Description | CRUK Cambridge Centre Retreat |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Professional Practitioners |
Results and Impact | The 2-day event aimed to bring all members across different disciplines together to share research advancements and exchange ideas, and facilitate future collaborations within the Centre. |
Year(s) Of Engagement Activity | 2022 |
Description | Cambridge Science Festival 2022 |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Public/other audiences |
Results and Impact | What is the Cambridge Festival? The interdisciplinary Cambridge Festival will took place from 31 March - 10 April 2022 with a mixture of on online, on-demand and in-person events covering all aspects of the world-leading research happening at Cambridge There will still be strong and distinct platforms for the sciences and the arts, humanities and social sciences. And the Festival will include a uniquely Cambridge, eclectic mixture of over 350 events and activities: from panel discussions, film premieres, and self-guided walking tours, to interactive activities for the whole family. Topics cover the breadth of Cambridge research and will be presented across the Festival's themes: Society, Health, Environment and Discovery! For 2023 only we've included a special fifth theme - Power. The University's Public Engagement team brings the Cambridge Festival to you. To find out about their other events such as Open Cambridge, and their training and development programme for researchers, please visit cam.ac.uk/public-engagement |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.festival.cam.ac.uk/ |
Description | Chairing Cambridge Pancreatic Cancer Symposium 2022 |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | A full day event for researchers and clinicians working on pancreatic cancer to hear about the latest pioneering translational research from around the world with over a hundred attendees. |
Year(s) Of Engagement Activity | 2022 |
URL | http://www.cambridge-pcc.org/event_03.html |
Description | EACR Conference in Seville, Spain 20-23 June 2022 |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | EACR 2022 is a four day congress dedicated to basic, preclinical and translational cancer research across a wide breadth of topics. It will highlight the latest research and bring together the cancer research community to inspire innovation and build knowledge, connections and collaborations. The European Association for Cancer Research (EACR) is a non-profit membership association dedicated to the advancement of cancer research. We have been bringing cancer researchers together at our congress and conferences since 1968, and EACR 2022 is our 28th congress. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.eacr2022.org/ |
Description | Fighting Cancer with the Immune System 28th September 2022, Downing College |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Professional Practitioners |
Results and Impact | About this event Fighting cancer with the Immune System: Exploring the physico-chemical and metabolic barriers to tumour immunity and immunotherapy. It is becoming clear that the physical, chemical and metabolic nature of the tumour microenvironment is a major determinant of tumour immunity and immunotherapy responses. This symposium aims to foster new interdisciplinary collaborations between cancer immunologists and physical/chemical biologists to break new ground in this emerging area. It is hoped that such interdisciplinary research will be attractive to future interdisciplinary funding bids and philanthropy. Confirmed speakers include: · Giulia Biffi, Cancer Research UK Cambridge Institute |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.bio.cam.ac.uk/research/molecules-and-cells-building-blocks-life |
Description | Frontiers in Organoid Medicine Symposium |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Frontiers in Stem Cell & Organoid Medicine Symposium will take place on March 24-25, 2022. Due to continuous rise of the omicron variant in the Ohio region, the Symposium will be held virtually. This international symposium, co-sponsored by The Center for Stem Cell & Organoid Medicine (CuSTOM) and RIKEN Center for Biosystems Dynamics Research (BDR), as well as a number of leading biotechnology companies, will focus on recent breakthroughs and acceleration of clinical translation, and will feature top academic researchers, industry scientists, as well as junior investigators who are emerging leaders in the field. The symposium will include topics from basic research to clinical and commercial translation of iPS cell and organoid technology. Workshop sessions will focus on major hurdles and opportunities in Organoid Medicine. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.organoidmedicinesymposium.org/ |
Description | Global Cancer Consortium - Pancreatic cancer Mini-Symposium |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Dr Giulia Biffi was an invited guest speaker and her talk title was 'Deconstructing Pancreatic Ductal Adenocarcinomas' followed by a Question and Answer session. |
Year(s) Of Engagement Activity | 2023 |
URL | https://glocacon.org/event/save-the-date-pancreatic-cancer-mini-symposium/ |
Description | Guest Speaker at Institute of Systems, Molecular and Integrative Biology at the University of Liverpool online on 26th of January 2023 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Over 60 pupils and practitioners attended via Zoom to the research organisation, which sparked questions and discussion afterwards, and the school reported increased interest in related subject areas. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.liverpool.ac.uk/life-course-and-medical-sciences/research/groups/molecular-biology/resea... |
Description | Hinterzartener Kreis der DFG für Krebsforschung May 19-22 2022 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | From Molecular Mechanisms to Cancer Therapy |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.dfg.de/download/pdf/dfg_im_profil/gremien/senat/hinterzartener_kreis_krebsforschung/prog... |
Description | Invited Speaker at Conference at Collegio Ghislieri, Pavia Italy |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | he Collegio Ghislieri organizes and hosts numerous cultural events, also on the proposal of current students or graduate students and with their collaboration. During each academic year, the College organizes on average three cultural events a week, ranging from meetings with leading personalities from the world of culture and professions to presentations of new books, from informative conferences on every theme of knowledge to restricted seminar meetings for specialists, from large international conferences to round tables on current issues. All these events, unless otherwise specified, are free access for the public. On our YouTube channel you can review the videos of the public initiatives of the Collegio Ghislieri by browsing the General Calendar of events on the homepage of Ghislieri.it and selecting the date of the chosen event, or simply browsing the titles of the conferences present day by day. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.ghislieri.it/collegio/attivita/conferenze/ |
Description | Joint Pancreatic Cancer Seminar with Early Cancer Institute |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Professional Practitioners |
Results and Impact | The seminar aimed to bring together experts in the fields of early cancer detection and pancreatic cancer to find out about the current state-of-play and what progress can be made together. Additionally, two charitites (CRUK and Pancreatic Cancer UK) spoke about funding opportunities within their organisations. |
Year(s) Of Engagement Activity | 2022 |
URL | https://crukcambridgecentre.org.uk/news/pancreatic-cancer-programme-and-early-cancer-institute-host-... |
Description | Milner Symposium, Milner Therapeutics Institute, Cambridge, UK |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Industry/Business |
Results and Impact | Symposium Overview Our Annual Symposium is an opportunity for scientists from academia and industry to discuss the latest academic and pre-clinical research and how it could be applied in the pharma and biotech industry to develop new treatments. It is our key networking event for Milner Therapeutics Institute partner organisations. If you attended the 2022 Symposium in person or online, we're glad you could join us! Thank you to our speakers, affiliated companies and to our Platinum Sponsor Lifebit and our Bronze Sponsors AltemisLab, Eagle Genomics and Sengenics. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.milner.cam.ac.uk/milner-symposium-2022/ |
Description | Molecules and Cells: Fundamental Biology of Cancer on 20th January 2023, Newnham College |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Professional Practitioners |
Results and Impact | The Molecules & Cells Theme is planning a 1-day meeting on 'The Fundamental Biology of Cancer' to be held early next term, on 20th January at Newnham College. The aim is to connect up researchers in the School who work on cancer and other relevant topics, to identify opportunities for networking and collaboration, and to develop engagement with the Cambridge Cancer Centre. We are pleased to have speakers confirmed from 8 different Departments and Institutes working on a diverse range of topics, from cell behaviour and signalling pathways to molecular structures modelling cancer heterogeneity. Please see the programme for full details. We aim to keep the meeting small, informal and PI-only, to replicate the networking success of previous Themes events. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.bio.cam.ac.uk/research/molecules-and-cells-building-blocks-life |
Description | PCUK Discovery & Translational Research Forum |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Other audiences |
Results and Impact | The 2023 Discovery and Translational Research Forum discussed some of the priority challenges faced by discovery and translational researchers in the UK and how researchers should work together to overcome them. The 2 day event covered the following topics: -How can preclinical studies improve clinical trials? -Detecting and treating early disease -Targeting the host -Targeting the tumour cells |
Year(s) Of Engagement Activity | 2023 |
Description | Participation in the awareness-raising, fund-raising bake sale, plant sale and charity walk |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Public/other audiences |
Results and Impact | Teamed up with group members to participate in the shine night walk to raise public awareness of pancreatic cancer and fund-raising for PCUK. A total amount over 1K was raised to support PCUK. |
Year(s) Of Engagement Activity | 2022 |
URL | https://twitter.com/BiffiGiulia/status/1593547598899683329?s=20 |
Description | Participation in the awareness-raising/fund-raising bake & plant sale event as part of World Pancreatic Cancer Day campaign |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Public/other audiences |
Results and Impact | Bake sale at CRUK Cambridge Institute to raise awareness of pancreatic cancer and raise fund for PCUK |
Year(s) Of Engagement Activity | 2022 |
URL | https://twitter.com/CRUKCamPancCan/status/1593307879611711494?s=20 |
Description | Postdoc Futures: Empowering Women in Cancer Research |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Postgraduate students |
Results and Impact | Chair of the 'Roundtable discussions: practical solutions for supporting progression' interactive session which focused on practical solutions and the most powerful, actionable ideas for you and CRUK to take forward to help address structural barriers to progression. |
Year(s) Of Engagement Activity | 2023 |
Description | Postdoc futures: empowering women in cancer research |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Postgraduate students |
Results and Impact | 7 March 2023, 12.30 PM - 7 March 2023, 5.30 PM The Royal Society, 6-9 Carlton House Terrace, London SW1Y 5AG Cancer Research UK (CRUK) is celebrating International Women's Day 2023 by bringing together women from across our postdoctoral researcher community to connect, build collaborations and discuss together potential solutions to improve progression for women in cancer research. If you're a postdoctoral researcher funded by CRUK or based at a CRUK core-funded Institute and a woman, you're invited to join us for this unique event to network and connect with other postdoctoral researchers from across our CRUK network in an open and informal setting. You'll hear inspiring talks and practical tips from women who have had successful careers both in, and outside of, academia. Together we'll discuss actionable solutions and ideas for how to improve progression for women in cancer research. This is both so you feel empowered to take the next step in your career whatever your chosen career path and to help CRUK identify priority actions we can take as a research funder to help address structural barriers to progression. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.bristol.ac.uk/cancer/events/2023/cruk-7mar.html |
Description | Presenting at AACR in Boston, USA |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | This will be the 8th AACR Special Conference on Pancreatic Cancer, which has become one of the most popular organ site programs, attracting 400-500 attendees each meeting. Spanning basic, translational and clinical research, this conference will address the latest developments in all areas of pancreatic cancer research. The program will focus on incorporating numerous talks from submitted abstracts to highlight the advancements and diversity of the pancreatic cancer research field. Special sessions that present cutting-edge research, career development opportunities, and discuss controversies in the field will be exciting for both young and established investigators alike. Make plans now to participate in this stimulating conference. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.aacr.org/meeting/aacr-special-conference-pancreatic-cancer-2022/ |
Description | Purple Rainbow Pancreatic Cancer Podcast |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | The primary purpose of this podcast series is to inform, but it does not constitute medical or other professional advice or services. Episode held on 17 November 2022. |
Year(s) Of Engagement Activity | 2022 |
URL | https://podcasts.apple.com/gb/podcast/giulia-biffi/id1440840869?i=1000586518049 |
Description | The CRICK Somatic Evolution and Tumour Microenvironment |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | SETM joins researchers for a day of talks and discussion, with the focus on improving our understanding of cancer evolution - from normal somatic evolution to cancer progression, and the impact of the tumour microenvironment. This year, we're going hybrid! Attendees are welcome to join on-site (at the Crick) or can join remotely through Zoom. We are limited to 120 attendees on site so please register using the appropriate ticket type (either 'In person' or 'Virtual'). |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.eventbrite.com/e/somatic-evolution-and-tumour-microenvironment-setm-hybrid-symposium-202... |
Description | The London Pancreas Workshop 2023 |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | A forum for state-of-the-art clinical research in pancreatic cancer. Speakers presented talks on early diagnosis, treatment and laboratory developments for pancreatic cancer. |
Year(s) Of Engagement Activity | 2023 |