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EN-REACH: Every Newborn - Reach up Early Education intervention for All Children in Bangladesh, Nepal & Tanzania

Lead Research Organisation: London Sch of Hygiene & Tropic. Medicine
Department Name: Epidemiology and Population Health

Abstract

The Sustainable Development Goals (SDGs) target the unfinished agenda for child survival with 5.3 million deaths of children before their fifth birthday. Importantly, the SDGs also reflect families' and national governments' aspirations that all children thrive as well as survive, meeting their full developmental potential. Unfortunately, children most at risk include those with neurodevelopmental delays and developmental disabilities like cerebral palsy, who are less likely than their peers to access pre-primary and primary school education. Whilst 48% of low- and middle-income countries (LMIC) countries have policies to address pre-primary education, there remain major gaps in provision, and major gaps for evidence-based, feasible approaches that are inclusive of children with NDD/D.

OPPORTUNITY: 'Reach Up' (a Jamaican home visiting programme) is one of the most evidence-based parenting programmes to support early child development and educational outcomes. Effects have been seen into adulthood, including increased earning power. Up until now 'Reach Up' has focused on children under 3 years of age and has not included those with severer developmental delays and disabilities. Effects on pre-school readiness children at the age of 5 years, an important factor in longer term educational achievement, have not to date been examined and is the focus of the 'Every Newborn-Reach Up Early Education Intervention For All Children' (EN-REACH) research

PARTNERSHIP: Our proposal builds on a well-established, equitable partnership since 2015 between three leading research institutions in Bangladesh, Nepal and Tanzania and the UK. We have a cohort of 2,000 children, now aged 2-3 years, in these three countries to compare accuracy and feasibility of range of early child development (ECD) assessment tools, known as the EN-SMILING study. EN-SMILING is partnering with the World Health Organization and UNICEF, to contribute to accurately measuring ECD and detecting disability early in children in LMICs and provides. It provides a timely opportunity to rigorously test more feasible ways to improve educational outcomes for all children, including those with disabilities.

OBJECTIVES:
The EN-REACH study has 3 objectives:

Objective 1: INNOVATION
To adapt the existing "Reach Up" parenting package to include those with disability and additional materials to support pre-school readiness for all children.

Objective 2: IMPACT EVALUATION
To conduct a 'quasi-experimental' research study to compare early child development markers for school readiness and other important development, health and well-being outcomes for children and their families between those receiving the adapted "Reach-Up" package, and those who did not.

Objective 3: IMPLEMENTATION:
To improve our understanding of important factors in implementing the new adapted 'Reach up' package to support integration of the package into routine child health systems if it is found to be effective.

IMPACT EXPECTED:
EN-REACH could have significant impact for children in these three high priority countries, both for education and care of children at risk of poor developmental outcomes, with strong links to national and global policy including MoHs WHO, UNICEF and many stakeholders. Direct research benefits will include identification and roll-out of testing tools to screen children for developmental delay and disability to ensure early detection of difficulties. This research would enable understanding of acceptability of the parenting package to be inclusive of children with disability more widely across Africa and Asia. Since the team have a 5-year track record of collaborative work, with strong site teams and have proven ability to deliver outputs and joint publications throughout 2020, ongoing effective work can be anticipated despite the COVID19 pandemic.

Technical Summary

Sustainable Development Goals (SDGs) include targets for the unfinished child survival agenda, given 5.3 million deaths of children before their 5th birthday, half in the neonatal period. SDG target 4.2 aims that, by 2030, all children access quality early child development (ECD), pre-primary education and are ready for primary education. However, children most at risk of poor educational outcomes, including those with neuro-developmental delay and disability (NDD/D), are less likely to access school, including pre-school services.

This proposal, co-led by Dr Jena Hamadani of iccdr,b and Prof Joy Lawn of LSHTM is called EN-REACH (Every Newborn - Reach up Early Education intervention for All CHildren) and will evaluate the impact and implementation of an adapted 'Reach Up' parenting program in in Bangladesh, Nepal & Tanzania with three objectives:

Objective 1: INNOVATION: To adapt 'Reach Up' parenting package for ECD for all children, inclusive of those with NDD and disability, in three diverse low-and middle- income countries (LMIC).

Objective 2: IMPACT EVALUATION: To use a quasi-experimental design to measure early child development markers for school readiness (cognition, psycho-social, etc), and child and caregiver quality of life after receiving the adapted "Reach-Up" package (delivered to 50% of the cohort, est:1000 children), compared to the other 50%.

Objective 3: IMPLEMENTATION: To undertake process evaluation of implementation, including examining barriers & enablers for uptake of adapted "Reach Up" package integrated into routine health systems.

EN-REACH aims to have significant impact for children and their families, at country level and on global policy for care of children with disabilities through links with global organisations such as UNICEF and WHO. This study will provide evidence on effectiveness and acceptability of a disability-inclusive and scalable parenting package in diverse Asian and African settings.

Publications

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KC A (2024) Co-designing interventions for a continuum of care for children with cerebral palsy in Developmental Medicine & Child Neurology

 
Title Let Hope Grow: Communicating family experiences of caring for young children with disability 
Description Let Hope Grow is a collaborative project between researchers, artists and families to raise public awareness around families experience of child disability after newborn conditions in Africa 
Type Of Art Artistic/Creative Exhibition 
Year Produced 2020 
Impact Highly positive review of the art exhibition in Lancet Child & Adolescent Health 
URL https://blogs.lshtm.ac.uk/marchblog/2019/04/17/let-hope-grow-advocating-for-children-with-disability...
 
Description Contributed to the development of Rwanda national policy on disability rehabilitation
Geographic Reach National 
Policy Influence Type Participation in a guidance/advisory committee
Impact Meeting the needs of young children with developmental disabilities intergrated into national policies of disability rehabilitation
 
Description Development of a WHO global programme for care and support of children with developmental disabilities and their caregivers
Geographic Reach Multiple continents/international 
Policy Influence Type Contribution to new or improved professional practice
 
Description Dissemination Event with Ministry of Education
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Meeting with Centre for Human Resource Development and Ministry of Education
Geographic Reach National 
Policy Influence Type Contribution to new or improved professional practice
Impact Introduction of new measurement tool to identify school readiness in children under 5 in Nepal.
 
Description Memorandum of Understanding between Mnistry of Health Uganda and LSHTM on early care and support for neonatal survivors with developmental disability
Geographic Reach Africa 
Policy Influence Type Contribution to a national consultation/review
Impact Renewed government committment t early care and support for children with disability and their families
 
Description Community scale-up of the Baby Ubuntu Early Intervention Programme in Uganda
Amount £93,000 (GBP)
Organisation Tropical Health & Education Trust (THET) 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2021 
End 05/2022
 
Description Developing stigma module for participatory training programmes for caregivers of children with cerebral palsy
Amount € 47,000 (EUR)
Organisation Lillian og Dan Finks Fond 
Sector Charity/Non Profit
Country Denmark
Start 03/2018 
End 09/2019
 
Description Developing the WHO Caregiver Skills Training 0-3 years programme for young children with developmental disability
Amount $48,000 (USD)
Organisation World Health Organization (WHO) 
Sector Public
Country Switzerland
Start 07/2022 
End 06/2023
 
Description Evaluation of the Ubuntu programmes for early child disability in East Africa. A cluster randomized controlled trial
Amount $1,098,000 (CAD)
Organisation Partners In Health 
Sector Charity/Non Profit
Country United States
Start 05/2023 
End 05/2026
 
Description Funding for Every Newborn - Reach up Early Education for All Children in Bangladesh
Amount £400,000 (GBP)
Funding ID GR-075636 
Organisation Porticus 
Sector Charity/Non Profit
Country Global
Start 01/2021 
End 12/2023
 
Description Partnership for Accelerating Newborn Survival Across Africa (PANSAA)
Amount £691,984 (GBP)
Funding ID UKRI685 
Organisation United Kingdom Research and Innovation 
Sector Public
Country United Kingdom
Start 03/2025 
End 03/2028
 
Description Technical Advisor to Bill & Melinda Gates Foundation - Neuroprotection Consultant
Amount £68,510 (GBP)
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2022 
End 10/2024
 
Description Transitioning a Bundle of Early Detection, Care and Support for Children with Developmental Disabilities in Rwanda
Amount $1,093,979 (CAD)
Organisation London School of Hygiene and Tropical Medicine (LSHTM) 
Sector Academic/University
Country United Kingdom
Start 06/2023 
End 06/2026
 
Description Dr Kate Milner -Neurodevelopmental Paediatric Advisor 
Organisation University of Melbourne
Country Australia 
Sector Academic/University 
PI Contribution Sharing of measurement toolbox for ages 4-6 years old - and technical expertise on designing educational materials to be inclusive of children with disabilities.
Collaborator Contribution Technical expertise in assessing neurodevelopmental disability in particular assessing vision and hearing in low resource settings. General oversight and advice on intervention study design and engaging parents of children with disabilities.
Impact Design of study and ethics protocol.
Start Year 2018
 
Description Dr Maureen Black - Chair Technical Advisory Group 
Organisation University of Maryland
Country United States 
Sector Academic/University 
PI Contribution N/A
Collaborator Contribution Provided oversight and technical advise on overall ethics protocol - in particular on measurement of early child development.
Impact Refined ethics protocol Chaired 1st TAG meetingM March 2023
Start Year 2022
 
Description FCDO PENDA consortium evaluations disability interventions 
Organisation Foreign Commonwealth and Development Office (FCDO)
Country United Kingdom 
Sector Public 
PI Contribution The PENDA consortium is collaborating with our team to support the evaluation of our programme of early care and support for young children with developmental disability and their caregivers in Rwanda
Collaborator Contribution Funding contribution towards data collection, supervisiom, management, analysis and dissemination
Impact Cluster randomised trial with embedded process and economic evaluations underway. Policy change in Rwanda relating to disability and rehabilitation for children
Start Year 2023
 
Description The Pediatric Developmental Clinic/Baby Ubuntu Programme Rwanda collaboration: Partners in Health 
Organisation Partners In Health
Country United States 
Sector Charity/Non Profit 
PI Contribution Providing expertise in clinical trials, process and economic evaluation
Collaborator Contribution Implementation partner for the programme and evaluation
Impact Evaluating a programme of early assessment, care and support for children at risk of developmental disabilities in Rwanda through a cluster randomised trial inclusive of process and economic evaluations
Start Year 2023
 
Description The Pediatric Developmental Clinic/Baby Ubuntu Programme Rwanda collaboration: Partners in Health 
Organisation Rwanda Biomedical Center
Country Rwanda 
Sector Hospitals 
PI Contribution Providing expertise in clinical trials, process and economic evaluation
Collaborator Contribution Implementation partner for the programme and evaluation
Impact Evaluating a programme of early assessment, care and support for children at risk of developmental disabilities in Rwanda through a cluster randomised trial inclusive of process and economic evaluations
Start Year 2023
 
Description UNICEF Nurturing Care and Partnerships - Boniface Kakhowbe 
Organisation UNICEF
Country United States 
Sector Public 
PI Contribution N/A
Collaborator Contribution Technical oversight on ethics protocol - in particular on integrating interventions into community spaces
Impact Advised on overall study protocol
Start Year 2023
 
Description WHO consultancy to develop a global programme of Caregiver Skills Training for Infants & Young Children with developmental disabilities 
Organisation World Health Organization (WHO)
Country Switzerland 
Sector Public 
PI Contribution Contributing content to this new WHO global training programme for young children with developmental disabilties and their caregivers. Our research team is contributing content specifically to meet the needs for children with cerebral palsy and other motor impairments.
Collaborator Contribution WHO are leading on this initiative
Impact A field test version of the programme will be launched later in 2024
Start Year 2022
 
Title 'Let's get ready' school readiness intervention 
Description Under this grant we have designed and piloted a nine session school readiness intervention inclusive of disability specific material in Bangladesh, Nepal and Tanzania with involvement from ministry of health and education in each country. Each country has completed 2 months of piloting with two groups of 10 caregiver-child dyads. Materials are now being updated and context specific material has been added. 
Type Therapeutic Intervention - Psychological/Behavioural
Current Stage Of Development Initial development
Year Development Stage Completed 2023
Development Status Under active development/distribution
Impact During development process a scoping exercise of available educational material in each country was conducted allowing for a full review of school readiness materials. 
URL https://lshtm-my.sharepoint.com/:f:/g/personal/eidejcha_lshtm_ac_uk/EijGXgivPH1GiHUJvb0l8lMBnKzgAhKB...
 
Title Ubuntu Hub website 
Description Website for the Ubuntu Hub learning platform of care and support programmes for children with developmental disabilities and their families. 
Type Of Technology Webtool/Application 
Year Produced 2018 
Open Source License? Yes  
Impact Improved engagement of implemntation partners in LMICs. Improved reach and coverage of earky care and support for children and their families 
URL https://www.ubuntu-hub.org/
 
Description (Early care and support for young children with developmental disability and their caregivers in East Africa: Baby Ubuntu. TANN CJ African Regional Convening to Support Parents and Caregivers, Geneva, Switzerland, online. 21-23rd June 2022. Invited speaker 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited speaker at the African Regional Convening to Support Parents and Caregivers, Geneva, Switzerland, online. 21-23rd June 2022. Presenting on Early care and support for young children with developmental disability and their caregivers in East Africa: Baby Ubuntu.
Year(s) Of Engagement Activity 2022
URL https://www.afro.who.int/publications/african-regional-convening-support-parents-and-caregivers-june...
 
Description A Call to Action: Neonatal Encephalopathy in Low- & Middle-Income Country settings. 12th International Congress of the Union of European Neonatal & Perinatal Societies, Krakow, Poland. 2nd-4th September 2022. Invited speaker 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact (1) A Call to Action: Neonatal Encephalopathy in Low- & Middle-Income Country settings. TANN CJ 12th International Congress of the Union of European Neonatal & Perinatal Societies, Krakow, Poland. 2nd-4th September 2022. Invited speaker
Year(s) Of Engagement Activity 2022
URL https://www.mcascientificevents.eu/uenps/
 
Description CHILDREN WITH DEVELOPMENTAL DELAY AT PRESCHOOL YEARS IN RURAL BANGLADESH: A DESCRIPTIVE ANALYSIS 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Discussion on the importance of early detection of developmental delays, referral pathways and targeted interventions which involved discussion with many practitioners working in this area.
Year(s) Of Engagement Activity 2023
 
Description Community of Practice for early care and support for children with developmental disabilies and their families 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Community of practice for professionals caring for children with developmental disabilities and their families. CoP has 523 members spanning more than 80 countries and territories.
Year(s) Of Engagement Activity 2022,2023
URL https://knowledge-gateway.org/working-in-community-children-cerebral-palsy
 
Description Every New-born Reach up Early Education Intervention for All children(EN-REACH): A cluster randomised trial in Bangladesh, Nepal and Tanzania of a parent group intervention for school 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Describing risk factors for school readiness at age 5 which involved lively debate around key areas for intervention design
Year(s) Of Engagement Activity 2023
 
Description Implementation Toolkit for Small and Sick Newborn care website with UNICEF, and reach of 55,000 unique users across >190 countries 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The Implementation Toolkit for Small and Sick Newborn Care was launched by NEST360 and UNICEF on November 17, 2021, World Prematurity Day and the event was co chaired by Prof Joy Lawn, who was the lead developer for NEST360 in partnership with UNICEF. The website has a with a brand neutral domain name (www.newborntoolkit.org) The primary audience for the Toolkit is implementers at national, regional, and facility levels with varying roles: doctors, nurses, biomedical engineers, policymakers, implementers, innovators, and researchers, among others. The Toolkit was co-designed with >300 implementers from all over the world, and brings together >1000 readings, tools, and implementation learnings that support WHO norms and standards to advance scale up of small and sick newborn care. It includes materials from many organizations including: data tools in open source, education resources, device landscaping and TPPs, and other global public goods.

The Toolkit website has been accessed by >55000 users from >190 countries during 2024
Year(s) Of Engagement Activity 2021,2022,2023,2024,2025
URL http://www.newborntoolkit.org
 
Description Neonatal Brain Health in Africa: Risks, Outcomes & Interventions. TANN CJ University of Trondheim, 12th May 2022. Invited speaker 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speakerUniversity of Trondheim, 12th May 2022.
Year(s) Of Engagement Activity 2022
 
Description Policy makers and Ministry engagement - Bangladesh 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Sensitisation workshop with policy makers - officials from and education and health ministers a presentation and open discussion improved engagement between officials and the study team resulting in involvement from and approval from ministry on study activities.
Year(s) Of Engagement Activity 2022
 
Description Policy makers and Ministry engagement - Nepal 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Sensitisation workshop with policy makers - officials from centre for education and human resource development (CEHRD) and education and health ministers a presentation and open discussion improved engagement between officials and the study team resulting in involvement from and approval from ministry on study activities.
Year(s) Of Engagement Activity 2023
 
Description Policy makers and Ministry engagement - Tanzania 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact An information evening held in Dar Es Salaam Tanzania to discuss EN-REACH with key policymakers and stakeholders (members from UNICEF Tanzania, and the ministry of education) were invited. The overall aims and objectives of EN-REACH were presented followed by a discussion with stakeholders.
Year(s) Of Engagement Activity 2022
 
Description Presentation to the annual European Society for Disability Research conference in Lausanne 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact In this presentation (Let's Grow Together: Lessons from the Field in Malawi) I shared some of the some of the main results from the first stage of the project which used a community-based participatory research (CBPR) approach to gather the different experiences of parents who have children with disabilities in 10 villages. This approach involves a commitment to sharing power and resources and working towards beneficial outcomes for all participants, especially communities. CBPR, as a partnership approach, aims to equitably involve community members, organisational representatives and researchers, who contribute expertise and share decision-making and ownership.
A CBPR training workshop for the volunteer peer researchers from within community-based child care centres community and were trained to take part in interviewing their peers individually and within focus groups about their peers' experiences of early childhood development at the time. This included asking about the challenges, tensions, successes and views related to educational inclusion of their children into the centres. This training stemmed from the CBPR ethical guidelines.
The volunteer peer researchers were able to carry out a total of 9 focus group discussions with parents of children with disabilities and a further 9 recordings with volunteer pre-school teachers at 9 community-based community centres. I will discuss the process of how the transcripts were coded by the research team in collaboration with the peer researchers. Finally, I will reflect on whether we were able to maintain a power-sharing and balance whilst utilising this methodology and make some suggestions pn how it could be used in disability research in the global south.
Year(s) Of Engagement Activity 2017
URL http://alter-asso.org/lausanne-conference-2017/?lang=en
 
Description Supporting quality care for children with developmental disabilities during the pandemic: Challenges, solutions and silver linings. Tropical Health Education Trust conference 2022: Transformative pathways for a healthy recovery. 12th April 2022. 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Supporting quality care for children with developmental disabilities during the pandemic: Challenges, solutions and silver linings. Tropical Health Education Trust conference 2022: Transformative pathways for a healthy recovery. 12th April 2022.
Year(s) Of Engagement Activity 2022
 
Description WHO Meeting: Follow Up Care for Small Sick Newborns 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Geneva, June 2024 - presented baseline EN-REACH results and intervention design and materials. Feedback from WHO committee and participants. Noted by practitioners working in LMICs, major gap for supportive interventions for families post discharge.
Year(s) Of Engagement Activity 2024
 
Description We Thought Assessment Would Include Medicines": En-Smiling Qualitative Study of Routine Neurodevelopmental Assessments for Children in Bangladesh, Nepal and Tanzania 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at the International Developmental Peadiatrics Association in South Africa. Discussing importance of targeted routine measurement and the key barriers and enablers to assessment from the family perspective which involved interesting in depth discussion on the need for targeted comprehensive developmental screening.
Year(s) Of Engagement Activity 2023