Novel perimetry for identifying changes in visual field sensitivity in glaucoma
Lead Research Organisation:
CARDIFF UNIVERSITY
Department Name: Optometry and Vision Sciences
Abstract
Glaucoma, a chronic, progressive, age-related degeneration of retinal ganglion cells, is characterised by a slow, irreversible loss of visual field. It is the world's leading cause of irreversible blindness, affecting approximately 500,000 people in England and Wales, and 80 million people worldwide. With an ageing population, prevalence of glaucoma is rising. The peripheral visual field is slowly lost first, often going unnoticed by patients until advanced. Perimetry, the clinical method for identifying visual field loss involves presenting stimuli (spots of light) to the retina and determining the dimmest that can be detected at multiple locations in the field. However, the current standard perimetry test was designed >40 years ago, before the disease mechanisms in glaucoma were understood. A test design that was largely imported from the predecessor of the current standard (Goldmann kinetic perimetry) when tests became more automated, and high associated measurement variability, make it difficult to identify glaucomatous loss in the first instance and detect signs of progression. In fact, it can take many years of repeated measures to identify even moderate rates of deterioration. There is a timely need to redesign perimetry with 40 years of knowledge and understanding from basic science (physiological, psychophysical) and clinical studies, as well as with more accessible and affordable technology, in order to increase accessibility to testing, detect visual loss sooner, treat sooner, and improve prognosis for vision. In this multi-disciplinary, multi-site project, we will initiate the path to translation of a novel, more evidence-based form of perimetry from the laboratory to the clinical setting on the basis of two recently discovered functional biomarkers for glaucoma. We propose a stage 1 programme of research in which we will optimise various test parameters to maximise the accuracy, precision, and efficiency of the novel test for identification of glaucomatous visual field loss.
Technical Summary
Glaucoma is a chronic, progressive, degeneration of retinal ganglion cells, characterised by slow, irreversible loss of the peripheral visual field. Prognosis for vision is highest the earlier it is identified and treated. Perimetry, the clinical method for identifying visual field loss involves presenting stimuli (spots of light) to the retina to determine the dimmest that can be detected at multiple locations in the field. However, this technique has major limitations: a) low sensitivity to early damage, and b) high variability in moderate damage, making it difficult to identify further deterioration in those already diagnosed. The conventional test was developed >40 years ago, before the pathophysiology of glaucoma was understood, and has remained relatively unchanged since. With a design that is effectively arbitrary, it is unsurprising that glaucomatous changes are difficult to detect with the current standard clinical test. We recently discovered two functional biomarkers for glaucoma (changes in spatial and temporal summation) which will allow a redesign of perimetry for more accurate and precise measurements of changes in the visual field. In this multi-disciplinary, UK-wide, multi-site, project, we will initiate the path for translation of a novel, more evidence-based form of perimetry from laboratory to the clinical setting. This initial phase of the work will involve optimising clinical test parameters to maximise accuracy, test precision and efficiency in the novel test.
| Description | Association for Research in Vision and Ophthalmology Travel Grant |
| Amount | $1,100 (USD) |
| Organisation | BrightFocus Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 03/2024 |
| End | 10/2024 |
| Description | MRC IAA 2021 Cardiff University |
| Amount | £1,298,304 (GBP) |
| Funding ID | MR/X502960/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 03/2026 |
| Description | REVAMP Study Group |
| Organisation | Ulster University |
| Department | School of Biomedical Sciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The Principal Investigator, one Co-Investigator, Project Manager, one post-doctoral research associate, and Technology Transfer Officer form the Cardiff University-based members of the REVAMP Study Group. The Principal Investigator leads the REVAMP Study group, chairs formal meetings, oversees all aspects of the research including overseeing the conduct of the research (at a local level and across all sites), provides equipment and facilities, and provides supervision, mentorship, and training to the post-doctoral researchers and Project Manager. The post-doctoral research associate undertakes day-to-day research activities, provides specific research expertise, recruits and tests research participants, analyses research data, and contributes to the preparation and delivery of research outputs. All academic staff provide intellectual input. The Project Manager takes responsibility for day-to-day management of the research project, oversees the budget and spend on research, actively monitors progress, and works with the PI to support multiple workstreams. The Technology Transfer Officer works witht he Principal Investigator to ensure that intellectual property and commercial opportunities are identified and evaluated in line with Cardiff Uiversity's processes and policies. |
| Collaborator Contribution | Members of the REVAMP Study Group based at UCL Institute of Ophthalmology include a Co-Investigator and a post-doctoral research associate. Those based at Ulster University include two Co-Investigators and a post-doctoral research associate. The Co-Investigators oversee the conduct of the research at a local level, provide local equipment and facilities, and provide supervision, mentorship, and training to their respective post-doctoral researchers. The post-doctoral research associates at the respective institutions undertake day-to-day research activities, provide specific research expertise, recruit and test research participants, analyse research data, and contribute to the preparation and delivery of research outputs. All academic staff provide intellectual input. |
| Impact | The REVAMP Study Group is a multi-disciplinary team. The Principal Investigator, Co-Investigators and two of the three post-doctoral researchers are clinician scientists (optometrists and ophthalmologists). The Project Manager and one post-doctoral researcher hold law and psychology degrees respectively. A Technology Transfer Officer also forms part of the group. Research outputs are ongoing and will be updated as they become available, but those published to date are: - Patent: Visual Field Sensitivity Testing (WO2023187408). |
| Start Year | 2021 |
| Description | REVAMP Study Group |
| Organisation | University College London |
| Department | Institute of Ophthalmology UCL |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The Principal Investigator, one Co-Investigator, Project Manager, one post-doctoral research associate, and Technology Transfer Officer form the Cardiff University-based members of the REVAMP Study Group. The Principal Investigator leads the REVAMP Study group, chairs formal meetings, oversees all aspects of the research including overseeing the conduct of the research (at a local level and across all sites), provides equipment and facilities, and provides supervision, mentorship, and training to the post-doctoral researchers and Project Manager. The post-doctoral research associate undertakes day-to-day research activities, provides specific research expertise, recruits and tests research participants, analyses research data, and contributes to the preparation and delivery of research outputs. All academic staff provide intellectual input. The Project Manager takes responsibility for day-to-day management of the research project, oversees the budget and spend on research, actively monitors progress, and works with the PI to support multiple workstreams. The Technology Transfer Officer works witht he Principal Investigator to ensure that intellectual property and commercial opportunities are identified and evaluated in line with Cardiff Uiversity's processes and policies. |
| Collaborator Contribution | Members of the REVAMP Study Group based at UCL Institute of Ophthalmology include a Co-Investigator and a post-doctoral research associate. Those based at Ulster University include two Co-Investigators and a post-doctoral research associate. The Co-Investigators oversee the conduct of the research at a local level, provide local equipment and facilities, and provide supervision, mentorship, and training to their respective post-doctoral researchers. The post-doctoral research associates at the respective institutions undertake day-to-day research activities, provide specific research expertise, recruit and test research participants, analyse research data, and contribute to the preparation and delivery of research outputs. All academic staff provide intellectual input. |
| Impact | The REVAMP Study Group is a multi-disciplinary team. The Principal Investigator, Co-Investigators and two of the three post-doctoral researchers are clinician scientists (optometrists and ophthalmologists). The Project Manager and one post-doctoral researcher hold law and psychology degrees respectively. A Technology Transfer Officer also forms part of the group. Research outputs are ongoing and will be updated as they become available, but those published to date are: - Patent: Visual Field Sensitivity Testing (WO2023187408). |
| Start Year | 2021 |
| Title | VISUAL FIELD SENSITIVITY TESTING |
| Description | The present invention is concerned with a method and an instrument for measuring visual field sensitivity wherein the method relies on measuring, across a subject's visual field, the subject's response to a fixed-luminance stimulus, the area of which is modulated on subsequent stimulation; and said instrument is adapted to emit, at one or more locations across a subject's visual field, a fixed-luminance stimulus whose area is modulated on subsequent stimulation and wherein the instrument is also adapted to record the subject's response to said fixed-luminance stimulus by comparing the subject's response with the response in an age-matched normal group or by comparing the response to a prior determined baseline in order to identify any change in visual field sensitivity. |
| IP Reference | WO2023187408 |
| Protection | Patent / Patent application |
| Year Protection Granted | 2023 |
| Licensed | No |
| Impact | This patent has just been published, so no notable impacts as yet. This will be updated when notable impact has arisen. |
| Description | "International seminar on neurodegenerative disease and vision: could our eyes predict cognitive disease?", Santiago, Chile |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This seminar, organized by Universidad Santo Tomás, brought together a large group of local and international optometrists, researchers and students. The presenters included researchers and clinicians from universities in Australia, New Zealand, the United Kingdom, and Germany, to discuss novel approaches to detect neurodegenerative disorders. In my presentation, I focused on recent advances in glaucoma, addressing the neurophysiological changes that occur in the disease and highlighting our work in the field as part of the REVAMP study. At the end of the presentation, the audience reported to have changed their point of view regarding the current perimetric techniques to assess the visual field in glaucoma. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://enlinea.santotomas.cl/actualidad-institucional/tecnologia-medica-ust-santiago-llevo-a-cabo-i... |
| Description | CPD Talk on Perimetry and REVAMP for Hospital Optometrists |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | Continued Professional Development (CPD) accredited talk around the importance of perimetry, the limitations of current perimetry, and how research is looking to improve this. Presentation involved an outline of REVAMP background, aims and methodology. The audience were ~40 hospital optometrists currently working with the Belfast Health and Social Care Trust. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Conference presentation - 25th International Visual Field and Imaging Symposium 2024, Cardiff, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This was the XXVth International Visual Field and Imaging Symposium that was held in Cardiff, UK. This event was attended by a broad audience including researchers, clinicians and industry people working in the fields of imaging and perimetry. I presented the main findings of the REVAMP study phase I. My talk was well attended and I got some comments about the findings where some people shared their change in their views and opinions of perimetry. After the talk, there was an interesting discussion about the findings. I attended after finishing my work duties at the REVAMP team, and I got some interesting comments about future collaborations and side projects outside of the team. Finally, a couple of researchers approached me to ask for some further details about our work. |
| Year(s) Of Engagement Activity | 2022,2023,2024 |
| URL | https://www.ips-cardiff2024.com |
| Description | Conference presentation - The Association for Research in Vision and Ophthalmology (ARVO) 2024, Seattle, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The ARVO 2024 Annual Meeting, held in Seattle USA, was attended by over 11,600 vision science researchers, clinicians, and industry professionals. I presented some of the findings of the REVAMP study in a poster format. My poster was very well attended, with multiple visitors interested in the topic and the analysis conducted.Several attendees at the conference reported that the findings led them to change their views and opinions on how vision is affected in glaucoma, the underlying retinal changes that lead to visual loss, and the best way to design a visual field test for glaucoma. Some researchers indicated interest in collaborating with us in future research in this area and there were some initial plans made for involvement of those individuals in a future work package. As well as, 'Audience reported change in views, opinion or behaviours', other outcomes/impact of this activity were: Requests for further information, Requests about future involvement, and Initial plans made for future related activity |
| Year(s) Of Engagement Activity | 2022,2023,2024 |
| URL | https://www.arvo.org/annual-meeting/ |
| Description | Conference presentation - The Association for Research in Vision and Ophthalmology (ARVO) 2024, Seattle, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The ARVO 2024 Annual Meeting, held in Seattle USA, was attended by over 11,600 vision science researchers, clinicians, and industry professionals. I presented some of the findings of the REVAMP study in a poster format. My poster was very well attended, with multiple visitors interested in the topic and the analysis conducted.Several attendees at the conference reported that the findings led them to change their views and opinions on how vision is affected in glaucoma, the underlying retinal changes that lead to visual loss, and the best way to design a visual field test for glaucoma. Some researchers indicated interest in collaborating with us in future research in this area and there were some initial plans made for involvement of those individuals in a future work package. As well as, 'Audience reported change in views, opinion or behaviours', other outcomes/impact of this activity were: Requests for further information, Requests about future involvement, and Initial plans made for future related activity. |
| Year(s) Of Engagement Activity | 2022,2023,2024 |
| URL | https://www.arvo.org/annual-meeting/ |
| Description | European Glaucoma Society (EGS), Dublin, Ireland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | REVAMP Study findings to date were presented in two research poster at the European Glaucoma Society (EGS) conference in Dublin, Ireland by Dr Tony Redmond (Principal Investigator) and Dr Padraig J Mulholland (Co-investigator). Approximately 1,500 clinicians, researchers, industry (diagnostics & pharma) representatives, trainees, as well as some patients attended for a 4-day event in which new research in glaucoma investigation and management was presented and discussed. The poster presentation sparked discussion with clinician scientists, industry representatives and trainees. Some reported that their opinions regarding visual field testing had changed as a result of the presentation and there were several requests for more information and to set up follow-up meetings to discuss further. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://egscongress.org |
| Description | Event: "Nuevos horizontes en salud visual" ("New horizons in visual health"), Concepción, Chile |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This event brought together a large group of clinicians, including ophthalmologists, optometrists, and students from Chile, to hear updates in ophthalmology and visual sciences. My presentation focused on the latest advancements in perimetry, with a significant portion dedicated to show the outcomes of the first part of the REVAMP project. By the end of the session, the audience expressed great interest in the presentation, highlighting a shift in their perception of conventional perimetric tests and recognizing the potential of the REVAMP study. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://vaf.ucv.cl:8446/PortalEventos/evento.jsp?id=724 |
| Description | Institute Seminar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at one of a monthly meeting of the 'Visual Neuroscience and Function' Theme of the Institute of Ophthalmology, London. Attendance approx 15 vision science academics. Talk was entitles 'Towards more precise clinical perimetry' and covered the published work behind the current grant. Discussion demonstrated interest in the work. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Invited lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Invited presentation to the Institute of Neurobiology of the Bulgarian Academy of Sciences, in honour of the late Prof. Angel Vassilev. Attended by approx. 50 academic staff and clinical staff from local hospitals. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Oral presentation at The Association for Research in Vision and Ophthalmology (ARVO) conference (Seattle, USA) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The ARVO 2024 Annual Meeting, held in Seattle USA, was attended by over 11,600 vision science researchers, clinicians, and industry professionals. I presented the findings of the Phase 1 REVAMP study as an oral presentation. This was well attended, and I had many interesting questions and discussion afterwards. Several attendees at the conference reported that the findings led them to change their views and opinions on how vision is affected in glaucoma, the underlying retinal changes that lead to visual loss, and the best way to design a visual field test for glaucoma. Some researchers indicated interest in collaborating with us in future research in this area and there were some initial plans made for involvement of those individuals in a future work package. As well as, 'Audience reported change in views, opinion or behaviours', other outcomes/impact of this activity were: Requests for further information, Requests about future involvement, and Initial plans made for future related activity |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.arvo.org/annual-meeting/ |
| Description | Oral presentation at the Applied Vision Association (AVA) conference, Cardiff, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | The AVA conference, held in Cardiff, UK, was attended by approximately 100 vision science researchers, clinicians, and charity representatives. I presented the findings of the REVAMP study as an oral presentation and in a poster presentation. These were well attended, and I received interesting questions and discussion afterwards. Several attendees at the conference reported that the findings led them to change their views and opinions on how vision is affected in glaucoma, the underlying retinal changes that lead to visual loss, and the best way to design a visual field test for glaucoma. |
| Year(s) Of Engagement Activity | 2024 |
| URL | http://www.theava.net/meetings.php?s=christmas-2024-ava-meeting |
| Description | Oral presentation at the British Congress of Optometry and Vision Sciences 2024, London, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The British Congress of Optometry and Vision Sciences (BCOVS) conference is an annual national conference attended by researchers and practitioners from across the UK. I presented the results from the Phase 1 REVAMP study. The talk was very well received and generated much interest from, and discussion with, conference attendees. As well as the main outcome listed below, other outcomes/impact of this activity were: Requests for further information, Requests about future involvement. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://bcovs.co.uk/ |
| Description | Oral presentation at the British Congress of Optometry and Vision Sciences 2024, London, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The British Congress of Optometry and Vision Sciences (BCOVS) conference is an annual national conference attended by researchers and practitioners from across the UK. I presented the results from the Phase 1 REVAMP study. The talk was very well received and generated much interest from, and discussion with, conference attendees. As well as the main outcome listed below, other outcomes/impact of this activity were: Requests for further information, Requests about future involvement. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://bcovs.co.uk/ |
| Description | Oral presentation at the International Visual Field and Imaging Conference 2024, Cardiff, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The XXVth International Visual Field and Imaging Symposium was held in Cardiff, and was attended by vision science researchers, clinicians, and industry professionals who work within the field of imaging and perimetry. I presented data from the Phase 1 REVAMP study, looking at the relationship between functional measures and underlying ocular structure. The talk was well attended, and generated interesting discussion. Several attendees at the conference reported that the REVAMP findings led them to change their views and opinions on how vision is affected in glaucoma, the underlying retinal changes that lead to visual loss, and the best way to design a visual field test for glaucoma. Some researchers indicated interest in collaborating with us in future research in this area and there were some initial plans made for involvement of those individuals in a future work package. As well as the main outcome listed below, other outcomes/impact of this activity were: Requests for further information, Requests about future involvement, and Initial plans made for future related activity |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.ips-cardiff2024.com |
| Description | Paper and poster presentation at the Applied Vision Association (AVA) conference, Cardiff, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | The AVA conference, held in Cardiff, UK, was attended by approximately 100 vision science researchers, clinicians, and charity representatives. I presented the findings of the REVAMP study as an oral presentation and in a poster presentation. These were well attended, and I received interesting questions and discussion afterwards. Several attendees at the conference reported that the findings led them to change their views and opinions on how vision is affected in glaucoma, the underlying retinal changes that lead to visual loss, and the best way to design a visual field test for glaucoma. |
| Year(s) Of Engagement Activity | 2024 |
| URL | http://www.theava.net/meetings.php?s=christmas-2024-ava-meeting |
| Description | Paper and poster presentation at the UK & Éire Glaucoma Society (UKEGS) conference, Southampton, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The UKEGS conference, held in Southampton, UK, was attended by 100-500 vision science researchers, clinicians, and industry professionals. I presented the findings of the REVAMP study as an oral presentation and in a poster presentation. These were well attended, and I received interesting questions and discussion afterwards. Several attendees at the conference reported that the findings led them to change their views and opinions on how vision is affected in glaucoma, the underlying retinal changes that lead to visual loss, and the best way to design a visual field test for glaucoma. Some researchers indicated interest in collaborating with us in future research in this area and there were some initial plans made for involvement of those individuals in a future work package. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://glaucoma.uk/ukegs/ukegs-conference-2024/ |
| Description | Paper and poster presentations at the Hospital and Speciality Optometrists Annual Conference, Manchester, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Approximately 300-400 hospital-based optometrists, as well as primary care optometrists with a speciality qualification, attended this continuous professional development (CPD) event, held in Manchester, UK. Two paper presentations (with two accompanying poster presentations), were given in which results from the REVAMP Study to date were presented to delegates. An oral presentation and poster presentation were each given by the Principal Investigator (Dr Tony Redmond) and one of the Co-Investigators (Dr Padraig J Mulholland). The presentations generated discussion of the unmet needs in the field of glaucoma, the importance of accurate and precise perimetry, how recent advances in perimetry research have uncovered new functional biomarkers that can then be exploited in a novel clinical test, supported by proof-of-concept. There was great enthusiasm among delegates at the prospect of better perimetry. Several delegates reported their own, and their patients', experiences with current perimetry and that they look forward to seeing the findings from the REVAMP study translated to a better clinical test. In addition, delegates reported interest in knowing more about the REVAMP Study, findings so far, as well as future plans. Many requested further information, including about possible future involvement. Several also indicated that the discussion changed their views regarding perimetry in glaucoma, particularly that the current standard was not originally designed to test for specific biomarkers. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.aop.org.uk/events-and-education/events/2024/09/21/hospital-and-specialty-optometrists-co... |
| Description | Perimetry course for professional practitioners |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Approximately 10 - 20 delegates (mostly professional practitioners such as ophthalmologists, optometrists, orthoptists) attended a course, co-organised by Dr Tony Redmond (Cardiff University) and Prof. Dr. Nomdo Jansonius (UMCG, Groningen), entitled "Perimetry - from first principles to state-of-the-art interpretation of standard automated perimetry test results". The REVAMP study, including work leading up to the research, was discussed as part of the course. A formal Q&A session and general discussion followed the presentations, as part of the course. Delegates reported increased interest in the topics being discussed, and that they would take information they learned back to their respective practices or other places of work. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.everassociation.org/sites/all/themes/everassociation/documents/Past-Congress/Programme-B... |
| Description | Poster presentation at the Hospital and Speciality Optometrists Annual Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Approximately 150-200 hospital-based optometrists, as well as primary care optometrists with a speciality qualification, attended this continuous professional development (CPD) event, held in Warwick, UK. A poster, introducing the REVAMP study, including the background and context, its aims, schedule, study team, and implications, was presented at the meeting. The Principal Investigator (Dr Tony Redmond) presented the poster, with one of the Co-Investigators (Dr Padraig J Mulholland) also in attendance. The presentation generated discussion of perimetry in general, unmet needs, and how the REVAMP Study is addressing the unmet needs. Challenges and opportunities for the research were also discussed. Delates reported interest in knowing more about the study and many requested further information, including about possible future involvement. Several also indicated that the discussion changed their views regarding perimetry in glaucoma. The presentation also generated some initial discussion around future collaboration with other clinician scientists. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.aop.org.uk/events-and-education/events/2023/11/04/hospital-and-specialty-optometrists-co... |
| Description | Presentation to Fight For Sight CEO and UU Researchers |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | CEO of Fight for Sight attended Ulster University. Presentation given to him, and other 'eye' researchers within Ulster University, regarding background to REVAMP and results of Phase 1. Interest in our research was generated as evidenced by audience questions and comments. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Presentation to Research Colleagues |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented about REVAMP (background, main aims, general outline) to research colleagues within the Centre for Optometry and Vision Science (COVS), Ulster University |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation to clinical colleagues and students in Chile |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation of REVAMP (including background and aims) to colleagues, eye care professionals and optometry students across the country. It was an hybrid event (online/in-person). |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presentation to staff at Legacy Research Institute, Portland, OR, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Dr Tony Redmond gave an invited presentation on research that led to, and is being undertaken in, the REVAMP study to approximately 15-20 members of research and clinical staff at Legacy Research Institute (hosted by Legacy Health). Following the presentation, there was in-depth discussion about the research and its potential implications. Attendees reported increased interest in the role of spatial and temporal summation in the identification of visual loss in glaucoma. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Public Lecture Glaucoma UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Glaucoma UK Annual Lectures: I have 30 minutes to update the membership of this patient support organization on research progress (specifically mentioning the NAMinG trial and the REVAMP project) and take immediate questions following; further questions answered in a 45 min Q&A with other experts at the end of the afternoon, Immediate audience 50+ The presentation contents are then written up for the Glaucoma UK Insight magazine - audience entire membership (patient and professional) https://glaucoma.uk/about-us/our-membership-magazine/ Autumn 2022 edition |
| Year(s) Of Engagement Activity | 2022,2023 |
| URL | https://glaucoma.uk/events/glaucoma-uk-annual-lectures-2023/ |
| Description | REVAMP Stakeholder Group |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Every 6 months, the REVAMP Stakeholder Group meets to discuss research progress and plans for the next steps. The members critique the work, including future plans, and help shape the direction of the research and its visibility. They also feed in advice and insight into non-academic pathways to facilitate smooth downstream translation, where appropriate. They also hear about our research and report that they take anything they have learned back to their own practice (if a practitioner) or business. |
| Year(s) Of Engagement Activity | 2022,2023 |
| Description | REVAMP webpage |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | The REVAMP webpage, hosted on the Cardiff University website, describes the study aims and objectives, team, and ways in which people can get in touch/participate in the research. We have received numerous queries from the general public asking about how they can get involved with the research. The webpage has also been viewed by participants who have been recruited via other means, as a way of understanding more about the study. |
| Year(s) Of Engagement Activity | 2022,2023,2024 |
| URL | https://www.cardiff.ac.uk/research/explore/research-units/research-and-evaluation-of-area-modulation... |
| Description | Seminar to ophthalmologists and other health professionals at University Hospital of Wales |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Approximately 20 clinical staff (ophthalmologists, optometrists, and others) working in various sub-specialities, attended an afternoon seminar at the University Hospital of Wales, Cardiff. The seminar included presentations on clinical diagnosis of glaucoma including one by Dr Tony Redmond (PI) on 'Visual fields: improving their utility in the management of glaucoma'; The presentation discussed the REVAMP Study, including the background and contex, its aims, schedule, study team, beneficiaries and stakeholders, implications, and impact. It generated discussion of how the REVAMP Study is addressing unmet needs in glaucoma diagnosis, and how it links well with other significant ongoing research now and in the future. Challenges and opportunities for the research were also discussed. There was also a discussion about how to get involved in the study and how to request more information about the research. |
| Year(s) Of Engagement Activity | 2023 |