NERC Biomolecular Analysis Facility (Sheffield)

Lead Research Organisation: NERC British Geological Survey


The NERC Biomolecular Analysis Facility provides access to high-level genomics, metabolomics and bioinformatics provision through its five nodes. NBAF offers the very latest, class-leading technologies, including next-generation sequencing (Roche 454, Illumina and SOLiD), Sanger sequencing, microarray- and sequencing-based genotyping and expression profiling including the in silico design of oligoarrays (Agilent, Nimblegen). NBAF also supports metabolomics, medium-scale genotyping, bioinformatics and advanced data analysis techniques (genome and transcriptome assembly and annotation, expression analysis, etc.). The Facility consists of five nodes: a) NBAF-Sheffield - molecular genetics generation and analyses of molecular markers for population and evolutionary genetics; b) NBAF-Liverpool - high-throughput sequencing and microarray analysis technologies used for gene expression analysis, sequence capture, next-generation sequencing using Roche 454, AB SOLiD4 & IonTorrent technology, and bioinformatic support for analyses of these data; c) NBAF-Edinburgh - high-throughput sequencing and genomic analysis using Sanger, Roche 454 and Illumina technology, and bioinformatic support for analyses of these data; d) NBAF-Birmingham - metabolomics training, assay and analysis; e) NBAF-Wallingford - bioinformatics core training, bespoke analyses, and integrative analyses.


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Adams M (2015) Social genetic and social environment effects on parental and helper care in a cooperatively breeding bird in Proceedings of the Royal Society B: Biological Sciences

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Ahmed S (2009) Wind-borne insects mediate directional pollen transfer between desert fig trees 160 kilometers apart. in Proceedings of the National Academy of Sciences of the United States of America

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Almathen F (2016) Ancient and modern DNA reveal dynamics of domestication and cross-continental dispersal of the dromedary. in Proceedings of the National Academy of Sciences of the United States of America

Description We support many facility users each year. Some highlights are described in NBAF's Annual Report to NERC Services and Facilities.
Exploitation Route Conservation; informing policy makers.
Sectors Environment

Description We have assisted end users in their work which has, in turn, fed into practice and policy in the water industry, conservation and wildlife management. The Facility users will have reported in more detail on these.
Sector Environment
Impact Types Economic

Description Kim Mortega Poster Presentation (NBAF767) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Kim Mortega discussed her project with many interested colleagues in detail and received very good feedback, new ideas and improvements. she was also approached by several colleagues during breaks and evening activities.

Kim Mortega was invited to two labs for a postdoc position.
Year(s) Of Engagement Activity 2014