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Determining vitamin D status in precontact Western Alaska: a new method for exploring past health and dietary adaptations to high-latitude living

Lead Research Organisation: University of Aberdeen
Department Name: Archaeology

Abstract

This research will use newly-developed archaeological science approaches to target permafrost-preserved human hair from the precontact site of Nunalleq, Western Alaska (1450-1650 AD) in order to empirically-determine seasonal vitamin D status in an archaeological population for the first time. Vitamin D is essential for healthy skeletal growth and cardiovascular health, and deficiency is related to multiple diseases. The most important source of vitamin D in humans is ultraviolet B (UVB)-induced dermal (skin) synthesis of vitamin D3. However, at high latitudes, especially in winter, a lack of ultraviolet light of the appropriate wavelength leads to an increase in the prevalence of vitamin D deficiency, and dietary supply or supplementation becomes essential - a major environmental challenge for past and present populations living at high-latitudes today, including in Western Alaska and in the UK. Using novel analytical technology, our aim is to determine vitamin D concentrations in archaeological hair strands preserved at the precontact site of Nunalleq and to compare these new data with existing seasonal palaeodietary data, allowing the relationship between vitamin D status and seasonal dietary habits to be inferred for different individuals at the site.

Data generated will provide a baseline for the interpretation of modern and recent-historic (post-1960s) data concerning the relationship between contemporary vitamin D deficiency and consumption of traditional marine foods and allow us to explore the potential of this method in illuminating past human-environmental interactions and adaptations to high-latitude living. The outcomes of this project will lead to a better understanding of precontact lifeways, diet and health in Western Alaska. The results will also help define new pathways in the scientific investigation of ancient diet applicable to other archaeological sites and contexts and help forge new cross-disciplinary links between palaeodietary and palaeoenvironmental studies, and modern nutritional health research. Our results will also feed directly into ongoing public outreach initiatives centred around the Nunalleq site in the community of Quinhagak, Alaska (AK), including adding to an online Digital Museum and learning activities for local school children. These will enhance public understanding of vitamin D health, but will also enhance our understanding of the role of archaeo-health studies in reinforcing positive health practices today in Alaska and elsewhere.

Publications

10 25 50
 
Title Vitamin D exhibition in Nunalleq Digital Museum 
Description New permanent digital exhibition pages have been added to the Nunalleq Digital Museum, featuring the findings of this award as part of interactive animations allowing visitors to explore vitamin D content of Alaskan subsistence foods, with art by Alice Watterson. These can be found in the exhibition, under the sections 'Fall', then 'Preserving Food' as part of the house area (the information and interactive elements are then in the side-bar). 
Type Of Art Artistic/Creative Exhibition 
Year Produced 2024 
Impact These pages add a public health/health education aspect to the Digital Museum in an engaging and culturally-appropriate way. 
URL https://www.nunalleq.org/
 
Description We have determined that ancient hair samples preserve measurable quantities of metabolites of vitamin D, providing an empirical estimate of vitamin D status in the past. In our archaeological case study, based in coastal Western Alaska, it is becoming apparent there is a strong correlation between vitamin D status and marine food consumption, particularly the consumption of marine mammals and other high fat marine foods.
Exploitation Route The methodologies we have developed could be applied to other regions/archaeological case studies, and potentially also be developed further for modern medical science (i.e. as a non-invasive tool for the assessment of vitamin D health in modern individuals).
Sectors Agriculture

Food and Drink

Healthcare

Pharmaceuticals and Medical Biotechnology

Other

 
Description The results of this award have contributed to new a new (permanent) interactive exhibition at the Nunalleq Digital Museum on dietary reconstruction, vitamin D health and the vitamin D content of Alaskan subsistence foods.
First Year Of Impact 2024
Sector Culture, Heritage, Museums and Collections
Impact Types Cultural

 
Title Vitamin D and stable isotope data from human hair from the archaeological site, Nunalleq, Alaska 
Description Vitamin D (25(OH)D3 and 1,25(OH)D3) concentrations of incrementally-sampled preserved human hair from non-mortuary contexts at the Yup'ik archaeological site of Nunalleq Alaska (~1650 AD). Multi-isotope isotope data (carbon, nitrogen, sulphur, oxygen and hydrogen) for the same samples are found in accompanying files. 
Type Of Material Database/Collection of data 
Year Produced 2024 
Provided To Others? Yes  
Impact 383 views, and 10 downloads since September 2024 (Feb 2025) 
URL https://catalogue.ceh.ac.uk/id/8d5af777-384c-4114-af6b-69cdac239810
 
Description Collaboration with Boise State University (Linda Reynard) 
Organisation Boise State University
Country United States 
Sector Academic/University 
PI Contribution We have contributed samples and expertise in the preparation of those archaeological samples ahead of isotope analysis, as well as expertise in data interpretation.
Collaborator Contribution Linda Reynard has contributed sample analyses (oxygen and hydrogen isotopes) and expertise in analysing and interpreting oxygen and hydrogen isotope data.
Impact Papers are currently being prepared based on this collaboration.
Start Year 2023
 
Description Collaboration with University of Chicago (Maanasa Raghavan) 
Organisation University of Chicago
Country United States 
Sector Academic/University 
PI Contribution Provided samples, sample preparation prior to analyses and archaeological contextual information required for data interpretion
Collaborator Contribution Determining of genetic sex in archaeological human hair samples for purposes of enhancing dietary interpretations
Impact Paper in preparation based on the isotope and vitamin D analysis of hair, which incorporates sexing data.
Start Year 2023
 
Description Community subsistence and vitamin D health event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Collaborator Charlotta Hillerdal held an open day event in Quinhagak, Alaska for students and the local community during which a looping presentation on vitamin D health was played, presenting our main findings, and objects from the local museum (that originate from the excavations) were shown and discussed with community groups.
Year(s) Of Engagement Activity 2023
 
Description Press surrounding release of 2025 Scientific Reports paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Following the publication of the 2025 paper, there were multiple media requests including from the BBC (national Scottish) radio, and BBC (national) television. The work was covered on prime time news (BBC drivetime and Scotland's evening news show, Reporting Scotland), and in each case the story was paired with a vitamin D clinical specialist (including a pharmacist, and a representative from the food standards agency). Typical audiences for BBC Radio Scotland are >900,000 adults per week, and are similar for Reporting Scotland. I received a large number of comments from people I encountered afterwards who had seen the segments, asked more about the research and reported an increased interest both in the capacity of archaeological science and in the significance of vitamin D for health past and present. A number of people encountered described how they were going to start taking vitamin D supplements.
Year(s) Of Engagement Activity 2025