Component-Specific Air pollutant Drivers of Disease Risk in Early to Midlife: a pathway approach. (DREaM)

Lead Research Organisation: King's College London
Department Name: Analytical & Environmental Sciences

Abstract

Air pollution remains the major environmental cause of premature death globally, with long-term exposures to elevated concentrations of microscopic airborne particles and pollutant gases associated with both increased cardiovascular and respiratory hospital admissions and deaths. These adverse effects of living for long periods in areas of elevated pollutant concentrations are much greater than the those associated with short-term exposures, such as those associated with an air pollution episode, which has led to the hypothesis that air pollution not only aggravates disease symptoms in vulnerable groups, such as individuals with pre-existing chronic disease but may also contribute to their development. Consistent with this view, air pollution exposures have been shown to be associated with early signs of cardiovascular and respiratory disease, such as hypertension, high cholesterol, inflammation, and poor lung function in otherwise healthy individuals. This has significant policy implications as it implies reducing air pollution exposures in early to midlife has the potential to provide benefits far into the future, reducing age-related disease and their associated health costs. This expands our understanding of the vulnerability of the population to air pollution, emphasizing how important early life exposures are to health in later life. There are however considerable gaps in our knowledge of how air pollution exposures in childhood to mid-life can promote these adverse responses. Part of the problem here is that our understanding of how air pollution causes harm to the human body is largely based on studies that examine short-term responses to pollutants. We know very well that air pollution causes damaging oxidation reactions in the body and elicits inflammation, both in the lung and circulation, but what is less clear is how these responses relate to the effects of long-term, low-level cumulative exposures. Compounding this is the absence of clear biological indicators of long term exposures.

Recently it has become apparent that under a range of environmental stresses, DNA can undergo structural changes modifying the way in which genes are switched on and off. While some of these changes occur very rapidly, before resolving, others appear stable over time and potentially even inheritable across generations. As these alterations can occur in genes with functional roles in the regulation of inflammation, or the detoxification of particle components, identifying these DNA changes has the potential to provide insights into the underlying mechanisms contributing to the long-term effects of air pollution. This is the central aim of this study; to identify DNA modifications in genes in both children and adults that are associated with air pollution exposures, are stable across time and can be related to the early life risk factors for cardiovascular disease. To achieve this, we will estimate the exposures of children and adults in three large population cohorts using state of the art modeling that will allow us to consider the impacts of a broad range of chemical components within the air we breathe. This approach has the potential not only to improve our understanding of the components within the air pollution mix that increase our vulnerability to pollution but also to drill down into the underlying causal mechanisms. This will have significant policy impacts, both in terms of the development of targeted pollutant mitigation actions and communication strategies explaining the risks of air pollution to the 'healthy' general public before clinical symptoms become apparent in later life.

Planned Impact

The overall aim of this study, in terms of impacts beyond its academic objectives, is to provide an evidential base that supports air pollution mitigation to improve public health and reduce the personal and societal costs associated with NCD.

This project has many potential beneficiaries and its outputs are likely to act across a range of scales from local to international: (1) the most immediate impact will be to the public, particularly to those within the CHILL study areas in London and Luton, and the police within the occupational AIRWAVE cohort, who will kept informed of the research findings arising from this work throughout the course of the study. The study will highlight the early origins of disease and the role that air pollution can play in these processes by impairing lung growth or promoting increases in known risk factor for the development of CVD.(2) The second major group will be policy makers, who will need to respond to these findings to develop new abatement strategies, or mechanisms to reduce exposures in vulnerable groups. The increased focus on PM components, as opposed to simply particle mass has the potential to identify particularly harmful sources, which may aid in the development of more tailored solutions to the current challenges of urban air quality. (3) Relevant professional bodies working in health care (NHS), occupational health, transport or involved in the development of disease prevention strategies at local and national government level. (4) Third sector organisations, especially those involved in health advocacy and efforts to improve urban environments. (5) Industry, especially firms involved in the development of low cost air quality sensors, portable health technologies and air filtration systems for work places in schools. The findings may also influence major car manufacturers, to accelerate the development of low pollution vehicles. (6) Academic and research communities (as described in the academic beneficiaries section).

Dissemination to these wider stakeholder groups will be coordinated via the MRC-PHE Centre for Environment & Health's Community Advisory Board (Chaired by the study PI), comprising NGOs, politicians, patient groups, public health professional and representatives from press and industry. All members of the study team will be encouraged to present to this forum, with a focus on the development of ethical amendments, participant engagement in the CHILL and AIRWAVE cohorts, and effective communication of study findings. Because of the latency period between early to midlife exposures and the emergence of NCDs later in life there are significant challenges in communicating health risks, particularly during middle age, and we will work with closely with PPI/E professionals within our organisations to ensure we address this challenge. The vulnerable, are not only those with pre-existing disease, but those on the pathway to sub-optimal health in later life. More detail on our strategies to ensure effective engagement with the stakeholder communities outline above is included in our Pathways to Impact statement.

Publications

10 25 50

publication icon
Bakolis I (2021) Mental health consequences of urban air pollution: prospective population-based longitudinal survey. in Social psychiatry and psychiatric epidemiology

publication icon
Bosson JA (2019) Traffic-related Air Pollution, Health, and Allergy: The Role of Nitrogen Dioxide. in American journal of respiratory and critical care medicine

publication icon
Enlo-Scott Z (2021) Drug metabolism in the lungs: opportunities for optimising inhaled medicines. in Expert opinion on drug metabolism & toxicology

 
Description While the DREaM study is only in its initial year, we have already made significant progress in developing high resolution air quality models for the years covered by the two participating cohorts (CHILL and AIRWAVE) and have been successful in collecting saliva samples from the children participating in the CHILL study for the downstream genetic analyses. Fundamental to the objectives of DREaM is that there are contrasts in exposure between the two study sites, London and Luton, that can be related to the introduction of the Ultra Low Emission Zone in London. We are please to confirm that the scheme has produced significant reductions in vehicles entering the zone in London, associated with a 35% reduction in roadside nitrogen dioxide.
Exploitation Route The data from DREaM will ultimately help to inform public policy on health and urban design by demonstrating the benefit of air pollution reduction strategies on the health of children and young adults living within urban areas. The enhanced high spatial and temporal resolution air pollution models, allowing a degree of PM2.5 speciation, will provide an enhanced resource for future epidemiological investigations examining the associations between acute and long-term air pollution exposures with adverse health effects. The investigation of epigentic signatures of exposures, will both assistant in the development of long term biomarkers of air pollutant exposure, as well as help place these with mechanistic pathways to demonstrate a causal link poor air quality and adverse health outcomes.
Sectors Communities and Social Services/Policy,Construction,Education,Energy,Environment,Healthcare,Government, Democracy and Justice,Transport

 
Description One component of DREaM represents an enhancement of the ongoing NIHR-funded Children's Health in London and Luton study (Mudway co-I), which aims to address the impact of the introduction of the Ultra-Low Emission Zone (ULEZ) on the respiratory health and lung growth of children. To enable health assessment and DNA collections to be conducted during school time and to provide enhanced engagement to the participating schools we have worked with the Center of the Cell at QMUL to develop teaching sessions on DNA (including an introduction to epigenetics) to children in years 3,4 and 5. As of March 2020, these sessions have been delivered to over 5,500 children across the two study sites considerably uplifting scientific teaching within the partnering schools. We see this a being a key societal and educational output of the project, building upon the previous years teaching on air pollution. Our long- term ambition is to capture these teaching activities to provide a resource to all UK schools interested in the topic of how air pollution impacts on human health. The aims and objects of the CHILL and DREaM project have also been presented to the C40 CITIES group, the Local Trust (representing 150 disadvantaged communities within the UK), as well as various local government air pollution scrutiny committees (Southwark, Westminster, Brent, Ealing, Greenwich), with the objective of highlighting the importance of considering the early life impacts of air pollution on future disease risk. The study (CHILL, plus DREaM) was heavily highlighted during the GLA's consultation on the expansion of the ULEZ planned for October 2021, as an example research to support evidence-based policy.
First Year Of Impact 2019
Sector Education,Environment,Government, Democracy and Justice,Transport
Impact Types Societal,Policy & public services

 
Description Institution of Occupational Safety and Health - publication of report on the occupational risks of diesel exposures in professional drivers.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Publication on the effective mitigation measures business can make to reduce the exposure of professional drivers within their workforce. IOSH is an international agency and therefore the work has been disseminated globally.
URL https://iosh.com/media/8902/the-driver-diesel-exposure-mitigation-study-full-report.pdf
 
Description Presentation to Southwark councils environment scrutiny committee. (23/07/19)
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Membership of a guideline committee
Impact Provided evidence to Southwark's environmental scrutiny committee to help them shape their air quality mitigation plan.
 
Description Presentation to the Ealing Council scrutiny committee in the impact of air pollution on children's health (14/02/19)
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Membership of a guideline committee
Impact Provided evidence to Ealing council that fed into their air quality action plan for the borough.
 
Description Presentation to the Kingston Council's Citizens' Assembly on Air Quality - (10/11/19)
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Membership of a guideline committee
Impact I provide an update on the scientific action linking poor air quality to adverse health effects and reviewed the effectiveness of varying mitigation measures. This information was used by the citizens assembly to input into the councils local air quality strategy.
 
Description Hazard Identification Platform to Assess the Health Impacts from Indoor and Outdoor Air Pollutant Exposures, through Mechanistic Toxicology
Amount £848,942 (GBP)
Funding ID NE/W002213/1 
Organisation Natural Environment Research Council 
Sector Public
Country United Kingdom
Start 07/2021 
End 07/2025
 
Description Investigating the impact of Londonâ??s Ultra Low Emission Zone on childrenâ??s respiratory health
Amount £2,573,442 (GBP)
Funding ID PHR/16/139/01 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 01/2018 
End 12/2023
 
Description MRC Centre for Environment and Health
Amount £1,479,016 (GBP)
Funding ID MR/S019669/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 05/2019 
End 05/2026
 
Description West London Healthy Home and Environment Study (WellHome)
Amount £2,900,363 (GBP)
Funding ID NE/W002116/1 
Organisation Natural Environment Research Council 
Sector Public
Country United Kingdom
Start 07/2021 
End 07/2025
 
Description 38th AAAR Annual conference - "Biomarkers for air pollution research" - 30th Sept 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact State of the art presentation focused on molecular biomarkers of air pollution exposure.
Year(s) Of Engagement Activity 2020
 
Description Article in The Conversation - London air pollution is restricting children's lung development - new research (15/11/18) 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Article summarizing the findings of the Lancet Public Health article showing reduced lung volumes in children living within polluted inner city boroughs of London. Subsequently re-posted on the Apolitical website, which is specifically targeted at international policy makers.
Year(s) Of Engagement Activity 2018,2019
URL https://theconversation.com/london-air-pollution-is-restricting-childrens-lung-development-new-resea...
 
Description Article in The Conversation - London's Ultra Low Emission Zone - will it make the city healthier? (10/04/19) 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Public article on the the introduction of ULEZ in London.
Year(s) Of Engagement Activity 2019
URL https://theconversation.com/londons-ultra-low-emission-zone-will-it-make-the-city-healthier-114942
 
Description Belgian Respiratory AQ meeting - "The lung, the front line of defence and vulnerability to air pollution" - 29th Nov 2019 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A presentation on the impact of traffic related air pollutants on the lung
Year(s) Of Engagement Activity 2019
 
Description Bloomsbury Festival, London (21-22 October 2022) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Two day event focusing on the impact of air pollution on children's health. Used to highlight progress in the CHILL, CHILL Cog and DREaM projects.
Year(s) Of Engagement Activity 2022
 
Description Breathe 2022 - a collaboration with the artist Dryden Goodwin and Invisible Dust, with support from The Wellcome Trust, Arts Council, Lewisham council and the Bloomsbury Festival. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact A year long public art science collaboration to highlight the impact of air pollution on lung health. Launched on the 18th of May, but with public events and panels held throughout the year. Included public art displayed throughout London, leading up to a unveiling of a public/artist animation in Catford on the 30th November, which was also used as a launch event for the announcement of the extension of London's ULEZ, attended by the London Mayor. The animation was also the center piece of the events to mark the 10th year anniversary of the death of Ella Adoo Kissi Debrah (15th Fen 2023).
Year(s) Of Engagement Activity 2022,2023
URL https://invisibledust.com/projects/breathe-2022/
 
Description British Thoracic Society - "Clean Air Zones - The Motivation, Public Health Ambitions and Reality" - 18th Feb 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation on the evidence of the effectiveness of low emission zones in improving the populations respiratory health
Year(s) Of Engagement Activity 2020
 
Description CHILL teaching session: currently 3,000 primary school aged children in London and Luton since Sept 2021. Educational sessions designed with the QMUL Centre of the Cell. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Teaching session performed alongside our visits to schools as part of the CHILL study, which represents one of the key cohorts in DREAM. From Sept 2021 and ongoing until July 2022. Projected to reach over 6,000 primary school aged children over this period.
Year(s) Of Engagement Activity 2021,2022
 
Description Cheltenham Science Festival panel discussion: The Air We Breathe (06/06/19) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Panelist on discussion on the health risks associated with poor air quality at the Cheltenham Science Festival. Event attended by approximately 50 individuals.
Year(s) Of Engagement Activity 2019
 
Description Citizens Assembly - White City, addressing the alignments between transitions to NetZero objectives and traffic pollution mitigation. 20th Nov 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on the health impacts of air pollution on deprived inner city residents.
Year(s) Of Engagement Activity 2021
 
Description Clean Air Day Video with Dyson Ltd (7th Oct 2020) 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Video discussing the evidence linking air pollution to adverse health effects, but expanding the discussion to a consideration of exposures across both indoor and outdoor environments.
Year(s) Of Engagement Activity 2020
URL https://www.youtube.com/watch?v=m2-fukVo0Ug
 
Description Environmental Protection UK - "Impacts of Noise and Air Quality on Health" - 19th Nov 2020 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Update of the evidence linking air pollution and noise to adverse health effects to public health practitioners throughout the UK.
Year(s) Of Engagement Activity 2020
 
Description Evaluating the health impacts of indoor and outdoor pollutants on vulnerable populations within the urban environment 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Supporters
Results and Impact Presentation to the Guy's and St Thomas's Charity and other third sector workers on future funding needs in relation to air pollution.
Year(s) Of Engagement Activity 2022
 
Description Evidence to the London Assembly and contribution to their 'Clearing the air: pollution in London' report 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Provided evidence on the emerging health impacts of air pollution on health. Quoted in final report.
Year(s) Of Engagement Activity 2021
 
Description Gresham College Public Lecture on the Exposome (27th October 2022) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Gresham public lecture introducing the exposome concept and it's role in public health. Large audience reached through digital platform.
Year(s) Of Engagement Activity 2022
URL https://www.gresham.ac.uk/watch-now/exposome
 
Description Gresham College Public Lecture to mark the 70th anniversary of the London Smog (5th November 2022) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Lecture to mark the 70th anniversary of the London Smog, reached a large online audience.
Year(s) Of Engagement Activity 2022
URL https://www.gresham.ac.uk/watch-now/londons-air
 
Description Imperial Festival - Green space instillation (29/06/19) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact An instillation was produced to explore the potential health benefits of green space within the urban environment. Details below:

GREEN SPACE is an installation that explores the health benefits of green spaces in cities and how we connect with nature in an urban environment. This collaborative project brings together the work of Imperial College London researcher Charlie Roscoe, artist Enya Lachman-Curl, designer Robbie Thompson, musician Robbie Parks, and Science Museum curator Rupert Cole.
Year(s) Of Engagement Activity 2019
 
Description Institute of Air Quality Management - presentation on the latest evidence for the health effects of PM2.5 components on health (17/09/19) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation to air quality practitioners working in local government, or as small to medium size enterprises in the air pollution arena.
Year(s) Of Engagement Activity 2019
 
Description Institution of Occupational Safety and Health - "Diesel MItigation STudy (DeMIST)" - 28th Oct 2020 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Final presentation of results of out IOSH funded DeMIST study to an international audience of health and safety practitioners.
Year(s) Of Engagement Activity 2020
 
Description Invited lecture on the health Impacts of Air Pollution to Oxford University Medical undergraduates 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Undergraduate students
Results and Impact Invited presentation to help increase the understanding of the health impacts of air pollution among medical students.
Year(s) Of Engagement Activity 2022
 
Description Lecture for 'Off the Curriculum' on the Health Impacts of air pollution - 4th November 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Off the Curriculum is a charity that aims to expand the education of A-level students within deprived communities beyond their set curriculum and to provide them with mentorship to help them to fulfill their potential.
Year(s) Of Engagement Activity 2021
 
Description London Mayors International Air Quality Summit (23/10/19) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact On 23 October 2019, London hosted an International Air Quality Summit and Conference, in partnership with the World Health Organization, UK100 and C40 Cities. I presented an update on the ongoing work evaluating the impact of London's ULEZ on air quality and children's health in London, referencing ongoing work in the CHILL and DREaM studies.
Year(s) Of Engagement Activity 2019
URL https://www.london.gov.uk/what-we-do/environment/pollution-and-air-quality/international-air-quality...
 
Description MRC-Festival of Science (21/06/19): Pollution Pods educational day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact The MRC Centre for Environment and Health joined forces with the MRC Toxicology Unit to run an educational event on air pollution and health alongside Michael Pinsky's Pollution Pod instillation at Media City, Salford, Manchester on the 21st of June. We also supported the instillation with scientific advise on the simulated atmospheres within each pod, designed to replicate air pollution in a variety of world cities. The instillation, which was partnered with Transport for Greater Manchester as part the cities "Clean Air Week" ran from 17 - 23 June, attracting 2,400 public visitors. On the education day we hosted 180 primary children from 6 local schools. The instillation generated considerable media attention both within Manchester, nationally and world-wide - Manchester was one site on a world tour of the instillation, curated by Cape Farewell. Full details of the media coverage can be found here: http://www.michaelpinsky.com/reviews/
Year(s) Of Engagement Activity 2019
 
Description NERC report - contributor: lead by the Hutton Institute - addressing research gaps linking environmental factors to mental health 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Contributed through a number of panels to the Valuing Nature report addressing knowledge and gaps linking environmental factors to adverse mental health outcomes.
Year(s) Of Engagement Activity 2021
 
Description New Scientist Live - London (7-9th October 2022) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Three day event held in London. We had a stand highlighting the work of the MRC Centre for Environment and Health and the associated NIHR HPRUs. The event was used to showcase progress in ongoing projects including DREaM, HIP-Tox, CHILL, CHILL Cog and Wellhome. Two days for the general public and one school day.
Year(s) Of Engagement Activity 2023
 
Description New Scientist Live - Manchester (11th-13th March 2022) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Three day New Scientist Live Event in Manchester to highlight the work of the MRC Centre in Environment and Health and the associated HPRUs. Also used to highlight ongoing research projects including DREaM, CHILL, HIP-Tox and Wellhome.
Year(s) Of Engagement Activity 2022
 
Description New Scientist Live - NIHR health protection research unit in the health impact of environmental hazards (10-13/10/19) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The NIHR HPRU in the health impacts of environmental hazards had a stand at the New Scientist Live for the 4-days of the event, covering ongoing projects within the theme, including work on the impact of air pollution on lung development, cognition and asthma risk, e-cigarettes, public health surveillance etc. Over the four days of the event we interact with in excess of 2,000 members of the general public.
Year(s) Of Engagement Activity 2019
URL http://hieh.hpru.nihr.ac.uk/our-research/ppippe
 
Description New Scientist Live, North - Manchester 12th-14th March 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact We presented a stand on the impact of environmental hazards on health, with focused activities on air pollution, including DREaM.
Year(s) Of Engagement Activity 2022
 
Description Panel discussion on transport in the 21st Century - Royal Geographical Society - 9th October 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Presentation as part of Imperial College's Great Exhibition Road Festival.
Year(s) Of Engagement Activity 2021
 
Description Panel discussion to help inform members of the general public on their potential to take legal action against the government for failure to meet air pollution limit values - with Client Earth. - 29th Nov 2021 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact This was a session set up by Client Earth to present air pollution evidence to individuals thinking of taking a class action against the UK government to ensure they were fully aware of the evidence base supporting any such action.
Year(s) Of Engagement Activity 2021
 
Description Panelist for air quality meeting - Islington Clean Air Parents (25/11/19) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presented up to date information on the impacts of air quality on health.
Year(s) Of Engagement Activity 2019
 
Description Pollution Pods educational day at Brownsea Island, Poole, Dorset (25/10/19) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Brownsea Island, Poole, Dorset (2,279 public visitors) 25 - 29 October
Partnered with Activate Performing Arts and supported by the National Trust and Arts University Bournemouth (AUB)
25 October Education Day; 60 primary children, 120 AUB students, many families
Year(s) Of Engagement Activity 2019
URL http://www.michaelpinsky.com/project/pollution-pods/
 
Description Pollution Pods educational day at Old Football Ground, Portland, Dorset (01/07/19) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact As part of the national tour of Micheal Pinksy's Pollution Pods we supported a number of educational event in areas of social deprivation and low social capital. We supported the visit of the pods to the Old Football Ground, Portland, Dorset with tours of the instillation, lectures and a range of activities focused on the early life impacts of air pollution on the lung. Overall there were 936 public visitors, with 60 primary children and 40 family members on the eduction day on the 1st July.
Year(s) Of Engagement Activity 2019
URL http://www.michaelpinsky.com/project/pollution-pods/
 
Description Presentation and Q/A with the Dulwich and Herne Hill Safe Roads to School committee (30/01/19) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Presented evidence on the impact of traffic related pollution on children's health. Resulted in numerous invitations to speak more widely on the topic throughout the SE London schools network.
Year(s) Of Engagement Activity 2019
 
Description Presentation and panel discussion for 'Mum's for Lungs' on the hazards of emissions from wood burning 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact To address public concerns about the health impacts of wood smoke
Year(s) Of Engagement Activity 2022
 
Description Presentation on the Health Impacts of Air Pollution as part of the UKRI's MRC Engagement series - Oct 14th 2022 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Presentation across all UKRI Centres/Units. including supporting staff
Year(s) Of Engagement Activity 2021
 
Description Presentation to parents of children attending Alleyns school, Dulwich (14/03/19). 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Presentation to the school community about effective measure to reduce air pollution around their school.
Year(s) Of Engagement Activity 2019
 
Description Presentation to the Guy's and St Thomas' NHS Foundation Trust cardiac support group (13/01/20) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Patients, carers and/or patient groups
Results and Impact Talk to patients attending the cardiovascular out clinic at Guy's hospital, focusing on the long term impacts of air pollution on the heart and circulation.
Year(s) Of Engagement Activity 2020
 
Description Presentation to the One Health meeting in Chiang Mai, Thailand on the impact of poor air quality on early life developmental trajectories (21/10/19) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Supporters
Results and Impact Outlined the evidence on the impacts of air pollution on early life to a diverse audience of Thai academics and policy makers. Resulted in new collaborations and a new British Council funded Newton Fund - Institutional Links pilot project.
Year(s) Of Engagement Activity 2010,2019
 
Description Presentation to the Putney Society, London on the expansion of the ULEZ (28/10/19) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Provided evidence on the evidence for the benefit of air pollution mitigation measures to improve children's respiratory health. Fed into a wider GLA consultation into the proposed expansion of the ULEZ.
Year(s) Of Engagement Activity 2019
 
Description Provided evidence to the London Assembly Environmental Audit Committee - 22nd Feb 2022 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Evidence provided as part of the rolling review of the GLA's air quality strategy.
Year(s) Of Engagement Activity 2022
 
Description Public meeting in Thailand over two days on the health impacts of air pollution - 14th Dec 2021 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact A 2-day meeting on air quality in Thailand and it's impact on health. The first day was focused to members of the general public, the second to policy makers with inputs from local and national Thai government.
Year(s) Of Engagement Activity 2021
 
Description Routes to Clean Air Presentation on the new WHO Air Quality standards - Bristol, 11th October 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Talk to public health practitioners and business working in the air quality arena on the new WHO air quality standards.
Year(s) Of Engagement Activity 2021
 
Description Royal Society of Chemistry - Air Pollution Metallomics - 10th Nov 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Presentation on the hazard of metals/metalloids within ambient particulate matter on human health.
Year(s) Of Engagement Activity 2021
 
Description Teaching provision to children within the CHILL cohort in association with QMUL's Centre of the Cell (across the full academic year Sept 2019 - April 2020) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact To support the ongoing work with the CHILL cohort for the DREaM project objectives we designed teaching for years 3, 4 and 5 across schools in London and Luton. To date we have provided teaching on DNA and epigenetics to over 5,500 children.
Year(s) Of Engagement Activity 2019,2020
 
Description The Air we Breathe - Information video in association with Greenpeace 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Information video on the short and long terms risks of air pollution.
Year(s) Of Engagement Activity 2020
URL https://vimeo.com/407273275
 
Description The air we breathe - a Client Earth event with the Arts Club (London - 11/11/19) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact This event at the Art Club in London was designed to allow a discussion of the current evidence on on air pollution and health and mitigation measures with influential members of the creative industries. Several high profile politicians were in attendance and areas of significant policy relevance were discussed during the event.
Year(s) Of Engagement Activity 2019
 
Description UKRI Festival of tomorrow, Swindon - teaching sessions delivered online to primary and secondary school children: 'The Boggling Brain' from the Children's Health in London and Luton Study, plus panel discussion on air pollution 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Online work shops delivered to multiple primary and secondary schools addressing the impact of air pollution on the brain. Delivered as part of the UKRI's involvment with Swindon's Festival of Tomorrow.
Year(s) Of Engagement Activity 2022
 
Description UKRI Net Zero Event, Parliament, Westminster - 21st October 2021 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Attended event and presented evidence of the co-benefits of traffic pollution mitigation on achieving Net Zero objects, but also emphasized some potential policy conflicts.
Year(s) Of Engagement Activity 2021
 
Description World Bank presentation on air quality in Pakistan (19/09/19) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact A presentation on what lessons can be learn't from London's approaches to reducing pollution in urban areas. An update to academics and policy practitioners working in Pakistan, as well as local and central government departments.
Year(s) Of Engagement Activity 2019