Assessment of the potential hazards of 2D nanomaterials to the environment

Lead Research Organisation: Imperial College London
Department Name: Materials

Abstract

The current focus of this project is to synthesise a set of model GO 2DNMs with highly controlled lateral size and test how the lateral dimension of the 2DNMs alters the viability (including cell metabolism and membrane integrity) of three different bacteria found in soils. The effect of prior interactions with natural organic matter on their subsequent toxicity of the bacteria will also be assessed. Toxicological endpoints will be coupled to the results of high resolution electron microscopy studies to relate intra/extracellular GO location to altered cellular metabolism of cell organelles and thus cellular reactivity. Since imaging the interaction of GO with bacteria presents an imaging challenge, given its low contrast against the cells, I will also assess the interaction of molybdenum disulphide with bacteria.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/R512540/1 01/10/2017 30/09/2021
1895942 Studentship EP/R512540/1 02/10/2017 01/10/2021 Seigo Masuda