Interactions and structural effects in model membranes and triglycerides of molecules playing key roles in oxidation

Lead Research Organisation: Imperial College London
Department Name: Dept of Chemistry

Abstract

There is recent evidence that the antioxidant mechanism of alpha-tocopherol (alpha-TOC) is strongly correlated with its location inside lipid bilayers or inverse micelles. In this project we plan to study the interactions, location, orientation and structural effects of antioxidants such as alpha-TOC in model lipid membranes, and correlate this with the antioxidant activity of the additive molecules. We will employ primarily x-ray and neutron scattering, solid-state NMR, optical microscopy, and uv-vis and fluorescence spectroscopy.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/R512540/1 01/10/2017 30/09/2021
1935994 Studentship EP/R512540/1 30/09/2017 29/09/2021 Divya Malia