Molecular basis of muscle alteration in response to spaceflight
Lead Research Organisation:
University of Nottingham
Department Name: School of Medicine
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
| Description | ISTRC 2020 |
| Amount | £250 (GBP) |
| Organisation | International Sarcopenia Translational Research Conference |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 06/2020 |
| End | 06/2020 |
| Description | REXUS/BEXUS Cycle 12 |
| Amount | € 200 (EUR) |
| Organisation | ESA - ESTEC |
| Sector | Public |
| Country | Netherlands |
| Start | 11/2018 |
| End | 12/2018 |
| Description | REXUS/BEXUS Cycle 13 |
| Amount | € 200 (EUR) |
| Organisation | ESA - ESTEC |
| Sector | Public |
| Country | Netherlands |
| Start | 11/2019 |
| End | 12/2019 |
| Title | Nemalife |
| Description | We have developed a device for automated analysis of C. elegans lifespan. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | We have used the nemalife in combination with the nemaflex to discover a new drug that delays muscle force decline with age in worms. The device is available for purchase. |
| Description | BAMMsat-on-BEXUS |
| Organisation | Cranfield University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The BEXUS project allows students to fly hardware in a stratospheric balloon flight. I am responsible for implementing the biological payload in a device to test its readiness for a balloon flight. I will assess the health of the payload and determine if the device is capable of maintaining the health of the payload. |
| Collaborator Contribution | BEXUS is a ESA lead project with collaborators German Aerospace Center (DLR), Swedish National Space Agency (SNSA), Esrange Space Center (SSC) Center of Applied Space Technology and Microgravity (ZARM) and EuroLauch. The project allows students to fly hardware in a stratospheric balloon flight. The team at Cranfield University is designing a device to house a biological payload in space and is using this flight to increase the flight readiness level of the hardware to allow for future space flight. the hardware is being designed and assembled using Cranfield Universities facilities and ESA and collaborators are helping with the design phase, funding and managing the flight and travel. Both Cranfield University and UK Space Agency are contributing funds for manufacturing the hardware. |
| Impact | Currently there are no outputs |
| Start Year | 2018 |
| Description | BAMMsat-on-BEXUS |
| Organisation | European Space Agency |
| Country | France |
| Sector | Public |
| PI Contribution | The BEXUS project allows students to fly hardware in a stratospheric balloon flight. I am responsible for implementing the biological payload in a device to test its readiness for a balloon flight. I will assess the health of the payload and determine if the device is capable of maintaining the health of the payload. |
| Collaborator Contribution | BEXUS is a ESA lead project with collaborators German Aerospace Center (DLR), Swedish National Space Agency (SNSA), Esrange Space Center (SSC) Center of Applied Space Technology and Microgravity (ZARM) and EuroLauch. The project allows students to fly hardware in a stratospheric balloon flight. The team at Cranfield University is designing a device to house a biological payload in space and is using this flight to increase the flight readiness level of the hardware to allow for future space flight. the hardware is being designed and assembled using Cranfield Universities facilities and ESA and collaborators are helping with the design phase, funding and managing the flight and travel. Both Cranfield University and UK Space Agency are contributing funds for manufacturing the hardware. |
| Impact | Currently there are no outputs |
| Start Year | 2018 |
| Description | BAMMsat-on-BEXUS |
| Organisation | UK Space Agency |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | The BEXUS project allows students to fly hardware in a stratospheric balloon flight. I am responsible for implementing the biological payload in a device to test its readiness for a balloon flight. I will assess the health of the payload and determine if the device is capable of maintaining the health of the payload. |
| Collaborator Contribution | BEXUS is a ESA lead project with collaborators German Aerospace Center (DLR), Swedish National Space Agency (SNSA), Esrange Space Center (SSC) Center of Applied Space Technology and Microgravity (ZARM) and EuroLauch. The project allows students to fly hardware in a stratospheric balloon flight. The team at Cranfield University is designing a device to house a biological payload in space and is using this flight to increase the flight readiness level of the hardware to allow for future space flight. the hardware is being designed and assembled using Cranfield Universities facilities and ESA and collaborators are helping with the design phase, funding and managing the flight and travel. Both Cranfield University and UK Space Agency are contributing funds for manufacturing the hardware. |
| Impact | Currently there are no outputs |
| Start Year | 2018 |
| Description | 5th World Congress on Hydrogen Sulfide in Biology & Medicine |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a poster on the project, resulted in discussions and potential collaborations |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.farmacologiaicbusp.com.br/en/5th-world-congress-on-hydrogen-sulfide-in-biology-and-medic... |
| Description | Big Bang Fair South West 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Attended Big Bang South West and interacted with roughly 6000 people, mostly primary and secondary school students. Activities included looking at normal and mutant worms, handling spaceflight hardware, and talking about science and spaceflight. Students and teachers were both enthusiastic with requests for school visits and expressions of interest in pursuing careers in science and engineering. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Experimental models in physiology - Physiological Society Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a poster |
| Year(s) Of Engagement Activity | 2018 |
| Description | Mitochondrial Medicine |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a talk |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://coursesandconferences.wellcomegenomecampus.org/our-events/mitochondrial-medicine-2019/ |
| Description | REXUS/BEXUS workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation to determine place on BEXUS project. Outcome was unsuccessful and place/funding was denied. |
| Year(s) Of Engagement Activity | 2018 |
| Description | REXUS/BEXUS workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation to determine place on project. Place on project and funding was awarded. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.rexusbexus.net/ |
| Description | Space Day 2019 (British interplanetary society) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Did an interactive display of normal and simulated spaceflight worms and discussed how we do space biology with the public at an event hosted by the British Interplanetary Society. Audience reported they were not fully aware of the UK space agency or what went into a space biology experiment. |
| Year(s) Of Engagement Activity | 2019 |
| Description | UK worm meeting 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation of a poster. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Wonder (University of Nottingham) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Attended Wonder hosted by the University of Nottingham. Activities included looking at normal and mutant worms, handling spaceflight hardware, and talking about science and spaceflight. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.nottingham.ac.uk/wonder/ |