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Targeting alternative splicing as a new cancer immunotherapy-phosphorylation of serine arginine-rich splicing factor (SRSF1) by SR protein kinase 1 (SRPK1) regulates alternative splicing of PD1 to generate a soluble antagonistic isoform that prevents T cell exhaustion. (2023)

Abstract

No abstract provided

Bibliographic Information

Digital Object Identifier: http://dx.doi.org/10.1007/s00262-023-03534-z

PubMed Identifier: 37973660

Publication URI: http://europepmc.org/abstract/MED/37973660

Type: Journal Article/Review

Volume: 72

Parent Publication: Cancer immunology, immunotherapy : CII

Issue: 12

ISSN: 0340-7004