Artistic and Creative Products
Multichannel images of fixed Platynereis dumerilii larvae after 3 days post-fertilisation. Labels:...
Artistic and Creative Products
Multichannel images of fixed Platynereis dumerilii larvae after 3 days post-fertilisation. Labels:...
Artistic and Creative Products
Multichannel images of fixed Platynereis dumerilii larvae after 3 days post-fertilisation. Labels:...
Collaboration
Investigating the role of primary cilia genes in human brain development using brain organoids
Collaboration
Primary cilia in Joubert Syndrome
Collaboration
The effects of cilia on nuclear invaginations and calcium signalling
Collaboration
Role of primary cilia in cortical development
Collaboration
Nordic Centrosome and Cilia Network
Collaboration
Nordic Centrosome and Cilia Network
Collaboration
Analysis of rho kinase inhibitors of ciliary function
Collaboration
Dr Dominic Norris, Polycystin-2 cilia mechnobiology
Collaboration
Finnish PCD genetics
Collaboration
PCD male fertility assessment
Collaboration
UK Cilia Network
Collaboration
Cryo-EM structure of cilia
Collaboration
From Astronomy to detecting Respiratory Cilia cells
Collaboration
From Astronomy to detecting Respiratory Cilia cells
Collaboration
Structural biology and molecular genetics of IFT80
Collaboration
Nordic Centrosome and Cilia Network
Collaboration
Analysis of cilia development and patterning
Collaboration
Cécilia GEFFROY internship student from Polytech, MARSEILLE, France
Collaboration
molecular organization of the ciliary transition zone
Collaboration
molecular organization of the ciliary transition zone
Collaboration
Structural biology and molecular genetics of IFT80
Collaboration
Cryo-EM structure of cilia
Collaboration
functional characterization of ciliopathy proteins
Collaboration
functional characterization of ciliopathy proteins
Collaboration
functional characterization of ciliopathy proteins
Collaboration
functional characterization of ciliopathy proteins
Collaboration
Frankfurt/Cologne clinical genetics
Collaboration
Frankfurt/Cologne clinical genetics
Collaboration
Frankfurt/Cologne clinical genetics
Collaboration
Frankfurt/Cologne clinical genetics
Collaboration
Collaboration with molecular basis of disease and therapeutics
Collaboration
Basal body structure and cell cycle-dependent biogenesis in Trypanosoma brucei.
Collaboration
Frankfurt/Cologne clinical genetics
Collaboration
Frankfurt/Cologne clinical genetics
Collaboration
Frankfurt/Cologne clinical genetics
Collaboration
Frankfurt/Cologne clinical genetics
Impact Summary
2016 (part of European Researchers' Night), held at the Glasgow Science Center, in September 2016...
Impact Summary
understanding of the role of cilia related genes in male infertility and the unknown function of...
Impact Summary
cytoplasmic dynein-2 molecular motor in humans. This has also led to the identification of a...
Intellectual Property
A tactile sensor, consisting of a flexible main body with embedded magnets, soft magnetized cilia...
Key Findings
cognitive functions unique to humans. In order to function properly, the cortex requires a large...
Key Findings
(CRS), which represents both a pressing clinical need and acts as a model of an interdisciplinary...
Key Findings
cilia to be resorbed and identified the pathway responsible
Key Findings
model organism to examine signalling processes in flagella. We identified how the movement of...
Key Findings
reconstruction of the beating swimming appendages (flagella) of Chlamydomonas algae. This is an...
Key Findings
facility not a s[pecific project: Vaughan: 3-D organisation of the flagellar pocket in T....
Key Findings
three-dimensional differentiated airway epithelial cell model at air-liquid interface (ALI) of the...
Key Findings
sperm cells interact with their fluid environment and surrounding walls. Sperm are tiny swimming...
Key Findings
series of genetics interactions between key proteins in the primary cilium, the sensory...
Key Findings
provide a detailed three dimensional view of the connections between basal bodies in the parasite...
Key Findings
postulated through analysis of TALPID3 homologues that TALPID3 has a Eumetazoan origin
TALPID3 has...
Key Findings
sensory cilia that sense flow stimuli, not only the type of flow (whether fast vibrations or flow...
Key Findings
spectrum of symptoms, but have in common that they all lead to impaired cilia formation or...
Key Findings
award:
1. We have produced single cell sequencing data to generate a single cell atlas of the...
Key Findings
in which the dynein-2 microtubule motor works in the formation and function of primary cilia. This...
Key Findings
functions such as mucociliary clearance in our airways and for sperm to swim. The molecular motors...
Key Findings
critical for cilia formation functions mechanistically, what lipid preferences it has, and at what...
Key Findings
mechanism by which neighbouring cilia and flagella synchronise their beating. These whip-like...
Key Findings
and biogenesis of connections between basal bodies was carried out and this manuscript is now in...
Key Findings
in TALPID3 lack primary cilia, a small organelle found on the surface of each cell.
As primary...
Key Findings
and Dchs1 mouse mutants. Cilia are parts of cells needed for movement of brain and spinal fluid....
Key Findings
(CRS), which represents both a pressing clinical need and acts as a model of an interdisciplinary...
Key Findings
first was to see IF we could see tiny organelles called primary cilia in the mouse growth plate and...
Key Findings
surface of almost every cell type in the body. They are critical for human physiology, as they they...
Key Findings
years research works we now can confirm that planar cell polarity is important in the skin,...
Products Interventions & Clinical Trials
CiliaScope automates the image collection of cilia for the diagnosis of Primary Cilia Dyskinesia...
Research Databases and Models
High content siRNA screen carried out to identify genes which when knocked-down, cause the...
Research Databases and Models
Supplementary material 1: Whole mount stain of a 72hr infected Nasal epithelial culture with...
Research Databases and Models
Developed mathematical model for cilia-driven flow near a rigid substrate in a (linear)...
Research Databases and Models
Paranasal sinuses are hollow spaces within the bones surrounding the nose. Of these, the largest...
Research Databases and Models
Research Databases and Models
list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Databases and Models
High content siRNA screen carried out to identify genes which when knocked-down, cause the...
Research Databases and Models
list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Databases and Models
Research Tools and Methods
The respiratory epithelium is an essential barrier but also an entry site for respiratory...
Research Tools and Methods
We generted a number of transgenic lines (>10) to manipulate phosphoinositide content in cilia.
Research Tools and Methods
We have used traditional paraformaldehyde fixation and histological staining combined with confocal...
Research Tools and Methods
1) list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Tools and Methods
1) list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Tools and Methods
1) list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...