Key Findings
extra fluid in the joint are the greatest risk factors identifiable at the time of the knee injury...
Key Findings
whole cadaveric knees to be tested in a laboratory. The methods allow the performance of...
Key Findings
extra fluid in the joint are the greatest risk factors identifiable at the time of the knee injury...
Policy Influence
Membership of a guideline committee
Policy Influence
Membership of a guideline committee
Engagement Activities
at Mellanby Centre for Bone Research Annual Meeting
Software and Technical Products
Project titled 'Understanding knee osteoarthritis from angle-and-force based acoustic emission...
Key Findings
joints, where cartilage is destroyed. Around 8.5 million people in the UK having moderate to severe...
Key Findings
as a treatment for people who have osteoarthritis (OA) affecting one side of their knee. It...
Key Findings
automatically matching (corresponding) and delineating (segmenting) anatomical structures in 3D...
Key Findings
and capability, in experimental and computational simulation systems, and fundamental knowledge of...
Impact Summary
demonstrated the potential of fibrillin-1 to enhance regeneration potential of ACL cells of both...
Software and Technical Products
The iKOALA app is a smartphone app for supporting knee Osteoarthritis self-management designed to...
Key Findings
several new research networks, collaborations and partnerships have worked towards establishing new...
Engagement Activities
assess patients with osteoarthritis in the knee received widespread news coverage by the BBC.
Collaboration
Acoustic emissions in biomechanics & sports science
Impact Summary
electrospinning (eg. shear forces) leads to significant alignment of molecules in a polymer and...
Further Funding
Lifestyle App (iKOALA)
Further Funding
Lifestyle App (iKOALA)
Artistic and Creative Products
Osteoarthritis webinar
Collaboration
KTH University - Bio-imaging
Software and Technical Products
The software package supports the development and planning of personalised high tibial osteotomy...
Key Findings
has been discovered or achieved as a result of the work funded through this award. *
A clinical...
Key Findings
20µM were conducted for 11 compounds (luteolin, isoliquiritigenin, curcumin, genistin,...
Engagement Activities
Annual Meeting, Houston, (Plenary)
Further Funding
the osteoarthritis knee joint
Impact Summary
economic burden to the UK, both from direct and indirect costs. In 2010-2011 approximately 181,350...
Policy Influence
Membership of a guideline committee
Impact Summary
poor, and this is a function of the replaced joint not replicating the biomechanics of the natural...
Key Findings
knee device prototypes were successfully tested and evaluated with human participants in the...
Engagement Activities
delivered by Hazel Fermor
Policy Influence
Participation in a guidance/advisory committee
Engagement Activities
Imaging reservation University of Exeter, 18 Spetember 2018; Dr Jay Dudhia Chair by invitation...
Collaboration
Genetics of Osteoarthritis Endophenotypes Working Group
Research Tools and Methods
A mouse mutations that results in osteoarthritis that shows a novel pathway responsible for joint...
Collaboration
AUGMENT study (Universities of Bristol, Southampton, Aberdeen, Cardiff and Queensland)
Collaboration
AUGMENT study (Universities of Bristol, Southampton, Aberdeen, Cardiff and Queensland)
Further Funding
to support and monitor rehabilitation therapy for the ageing population with knee osteoarthritis
Engagement Activities
Knee (BASK), 2018 Annual Conference.(POC017 McGonagle, UoL)
Key Findings
knee replacements
Defintion of a novel computational model to predict wear of polyethylene in the...
Collaboration
Zeggini (Munich)
Key Findings
made, giving additional evidence that smart knee implants could be introduced in future healthcare.
Collaboration
Shape Modelling
Key Findings
bio-inspired prosthetic knee joint based on the human bones dimensions. This novel bio-inspired...
Engagement Activities
in a session at the BORS meeting, Sept 2018
Further Funding
OsteoArthritis (PROP OA): a randomised controlled trial
Key Findings
method for investigating human knee and leg biomechanics. This method uses a robotic joint which...
Engagement Activities
stratify osteoarthritis patients held at RJAH Orthopaedic Hospital, Keele University
Key Findings
common deformity in active people), the joint alignment can change, but there are specific...
Collaboration
The World COACH Consortium (a Worldwide Collaboration in OsteoArthritis prediCtion of the Hip)
Collaboration
Tonia Vincent
Collaboration
Tonia Vincent
Key Findings
responses to tissue damaging stimuli indicative of central sensitisation - this provides additional...
Collaboration
Genetics of Osteoarthritis Consortium member
Collaboration
Genetics of Osteoarthritis Consortium member
Engagement Activities
crumbly old knees by collecting stem cells from the joint (POC017, McGonagle UoL)
Engagement Activities
Manchester, UK
Impact Summary
objectives, in priority order:
1. The development of a low-cost prosthesis that is suitable for use...
Engagement Activities
Osteoarthritis, Osteoarthritis and Cartilage, 27, S160
Engagement Activities
Masterclass
Intellectual Property
A design for a through knee prosthesis
Key Findings
model to study the optimal motor control strategy. Different performance criteria have been...
Impact Summary
clinically to improve outcomes in orthopaedic surgery. the technology base has been used clinically...
Collaboration
Proj 011 (Hammond)
Impact Summary
technology development was published in the Further Together series at the University of Leeds,...
Engagement Activities
guidance for Osteoarthritis Management
Engagement Activities
guidance for Osteoarthritis Management
Impact Summary
Providing marginal gains to improve transition time
2 - Developing a human-like device to improve...
Impact Summary
EMG sensors has been developed and integrated into the knee exoskeleton prototype to measure knee...
Impact Summary
industries and NHS clinicians. NHS clinicians have also used one of my findings to provide...
Collaboration
Professor Tonia Vincent
Research Tools and Methods
The new model result from a collaboration with Cardiff University and KU Leuven and as funded by...
Impact Summary
is to be developed further for use on a Knee spacer implant
Key Findings
directly from patient and healthcare providers that have driven the technical development of this...
Engagement Activities
NIR funded trial
Engagement Activities
osteoarthritis'
Research Databases and Models
Knee exoskeleton prototype validation data from laboratory trial sessions: The quantitative...