Key Findings
extra fluid in the joint are the greatest risk factors identifiable at the time of the knee injury...
Key Findings
whole cadaveric knees to be tested in a laboratory. The methods allow the performance of...
Key Findings
extra fluid in the joint are the greatest risk factors identifiable at the time of the knee injury...
Software and Technical Products
Project titled 'Understanding knee osteoarthritis from angle-and-force based acoustic emission...
Key Findings
joints, where cartilage is destroyed. Around 8.5 million people in the UK having moderate to severe...
Key Findings
as a treatment for people who have osteoarthritis (OA) affecting one side of their knee. It...
Policy Influence
Membership of a guideline committee
Policy Influence
Membership of a guideline committee
Engagement Activities
at Mellanby Centre for Bone Research Annual Meeting
Key Findings
automatically matching (corresponding) and delineating (segmenting) anatomical structures in 3D...
Policy Influence
Citation in other policy documents
Key Findings
and capability, in experimental and computational simulation systems, and fundamental knowledge of...
Impact Summary
demonstrated the potential of fibrillin-1 to enhance regeneration potential of ACL cells of both...
Software and Technical Products
The iKOALA app is a smartphone app for supporting knee Osteoarthritis self-management designed to...
Key Findings
several new research networks, collaborations and partnerships have worked towards establishing new...
Products Interventions & Clinical Trials
First discovered disease-modifying agent for knee osteoarthritis
Collaboration
Acoustic emissions in biomechanics & sports science
Engagement Activities
assess patients with osteoarthritis in the knee received widespread news coverage by the BBC.
Collaboration
KTH University - Bio-imaging
Further Funding
Lifestyle App (iKOALA)
Further Funding
Lifestyle App (iKOALA)
Software and Technical Products
The software package supports the development and planning of personalised high tibial osteotomy...
Key Findings
has been discovered or achieved as a result of the work funded through this award. *
A clinical...
Engagement Activities
(Nick Fuggle / Beth Curtis)
Artistic and Creative Products
Osteoarthritis webinar
Key Findings
20µM were conducted for 11 compounds (luteolin, isoliquiritigenin, curcumin, genistin,...
Further Funding
the osteoarthritis knee joint
Engagement Activities
Annual Meeting, Austin, (Plenary)
Impact Summary
economic burden to the UK, both from direct and indirect costs. In 2010-2011 approximately 181,350...
Impact Summary
poor, and this is a function of the replaced joint not replicating the biomechanics of the natural...
Research Tools and Methods
Automated system for evaluation of radiographic knee OA.
Key Findings
knee device prototypes were successfully tested and evaluated with human participants in the...
Engagement Activities
delivered by Hazel Fermor
Collaboration
AUGMENT study (Universities of Bristol, Southampton, Aberdeen, Cardiff and Queensland)
Collaboration
AUGMENT study (Universities of Bristol, Southampton, Aberdeen, Cardiff and Queensland)
Intellectual Property
This invention is in the field of medicinal chemistry. In particular, the invention relates to a...
Engagement Activities
Imaging reservation University of Exeter, 18 Spetember 2018; Dr Jay Dudhia Chair by invitation...
Collaboration
Genetics of Osteoarthritis Endophenotypes Working Group
Engagement Activities
Knee (BASK), 2018 Annual Conference.(POC017 McGonagle, UoL)
Key Findings
knee replacements
Defintion of a novel computational model to predict wear of polyethylene in the...
Further Funding
to support and monitor rehabilitation therapy for the ageing population with knee osteoarthritis
Collaboration
Collaboration with Ben Faber
Collaboration
Zeggini (Munich)
Further Funding
AI-driven Prediction and Cost-effective Rehabilitation Device Development
Key Findings
made, giving additional evidence that smart knee implants could be introduced in future healthcare.
Research Tools and Methods
A mouse mutations that results in osteoarthritis that shows a novel pathway responsible for joint...
Key Findings
bio-inspired prosthetic knee joint based on the human bones dimensions. This novel bio-inspired...
Impact Summary
technology development was published in the Further Together series at the University of Leeds,...
Engagement Activities
Osteoarthritis in the Oldest Old
Key Findings
method for investigating human knee and leg biomechanics. This method uses a robotic joint which...
Policy Influence
Citation in other policy documents
Policy Influence
Citation in other policy documents
Collaboration
Shape Modelling
Key Findings
has been developed for knee joint pain relief which includes a knee sleeve with dry fabric...
Further Funding
OsteoArthritis (PROP OA): a randomised controlled trial
Key Findings
common deformity in active people), the joint alignment can change, but there are specific...
Engagement Activities
in a session at the BORS meeting, Sept 2018
Policy Influence
Membership of a guideline committee
Key Findings
responses to tissue damaging stimuli indicative of central sensitisation - this provides additional...
Collaboration
Osteoarthritis Programme
Collaboration
Osteoarthritis Programme
Engagement Activities
Osteoporosis (ED)
Engagement Activities
crumbly old knees by collecting stem cells from the joint (POC017, McGonagle UoL)
Engagement Activities
Manchester, UK
Engagement Activities
stratify osteoarthritis patients held at RJAH Orthopaedic Hospital, Keele University
Policy Influence
Participation in a guidance/advisory committee
Collaboration
Genetics of Osteoarthritis Consortium member
Collaboration
Genetics of Osteoarthritis Consortium member
Impact Summary
objectives, in priority order:
1. The development of a low-cost prosthesis that is suitable for use...
Collaboration
Tonia Vincent
Collaboration
UCL and Andrew Pitsillides, Royal Veterinary College, Katherine Staines, University of Brighton....
Collaboration
UCL and Andrew Pitsillides, Royal Veterinary College, Katherine Staines, University of Brighton....
Collaboration
Tonia Vincent
Research Databases and Models
Knee exoskeleton prototype validation data from laboratory trial sessions: The quantitative...