Further Funding
Quidwai, Title: WDR35/ IFT121 functions like COPI vesicles to transport cilia specific cargo to...
Impact Summary
2016 (part of European Researchers' Night), held at the Glasgow Science Center, in September 2016...
Impact Summary
understanding of the role of cilia related genes in male infertility and the unknown function of...
Impact Summary
cytoplasmic dynein-2 molecular motor in humans. This has also led to the identification of a...
Key Findings
sperm cells interact with their fluid environment and surrounding walls. Sperm are tiny swimming...
Key Findings
cognitive functions unique to humans. In order to function properly, the cortex requires a large...
Key Findings
cilia to be resorbed and identified the pathway responsible
Key Findings
provide a detailed three dimensional view of the connections between basal bodies in the parasite...
Key Findings
spectrum of symptoms, but have in common that they all lead to impaired cilia formation or...
Key Findings
award:
1. We have produced single cell sequencing data to generate a single cell atlas of the...
Key Findings
in which the dynein-2 microtubule motor works in the formation and function of primary cilia. This...
Key Findings
functions such as mucociliary clearance in our airways and for sperm to swim. The molecular motors...
Key Findings
and biogenesis of connections between basal bodies was carried out and this manuscript is now in...
Key Findings
mechanism by which neighbouring cilia and flagella synchronise their beating. These whip-like...
Key Findings
reconstruction of the beating swimming appendages (flagella) of Chlamydomonas algae. This is an...
Key Findings
and Dchs1 mouse mutants. Cilia are parts of cells needed for movement of brain and spinal fluid....
Key Findings
facility not a s[pecific project: Vaughan: 3-D organisation of the flagellar pocket in T....
Key Findings
surface of almost every cell type in the body. They are critical for human physiology, as they they...
Key Findings
years research works we now can confirm that planar cell polarity is important in the skin,...
Key Findings
three-dimensional differentiated airway epithelial cell model at air-liquid interface (ALI) of the...
Key Findings
series of genetics interactions between key proteins in the primary cilium, the sensory...
Key Findings
model organism to examine signalling processes in flagella. We identified how the movement of...
Key Findings
postulated through analysis of TALPID3 homologues that TALPID3 has a Eumetazoan origin
TALPID3 has...
Products Interventions & Clinical Trials
Cilia are small structures that protrude from the surface of most animal cells like antennae. Like...
Products Interventions & Clinical Trials
Cilia are small structures that protrude from the surface of most animal cells like antennae. Like...
Research Databases and Models
Paranasal sinuses are hollow spaces within the bones surrounding the nose. Of these, the largest...
Research Databases and Models
list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Databases and Models
Research Databases and Models
High content siRNA screen carried out to identify genes which when knocked-down, cause the...
Research Databases and Models
Supplementary material 1: Whole mount stain of a 72hr infected Nasal epithelial culture with...
Research Databases and Models
Research Databases and Models
High content siRNA screen carried out to identify genes which when knocked-down, cause the...
Research Databases and Models
list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Tools and Methods
1) list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Tools and Methods
We generted a number of transgenic lines (>10) to manipulate phosphoinositide content in cilia.
Research Tools and Methods
We have used traditional paraformaldehyde fixation and histological staining combined with confocal...
Research Tools and Methods
1) list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Tools and Methods
1) list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...