Engagement Activities
the cilium in chondrocyte mechanotransduction
Collaboration
Analysis of primary cilia in human cells
Key Findings
and Dchs1 mouse mutants. Cilia are parts of cells needed for movement of brain and spinal fluid....
Collaboration
Functional Conservation in Ciliary Trafficking
Key Findings
surface of almost every cell type in the body. They are critical for human physiology, as they they...
Impact Summary
cytoplasmic dynein-2 molecular motor in humans. This has also led to the identification of a...
Engagement Activities
the University of Southampton
Collaboration
PCD male fertility assessment
Key Findings
model organism to examine signalling processes in flagella. We identified how the movement of...
Research Databases and Models
list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Research Databases and Models
list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...
Engagement Activities
Mucociliary Interactions
Collaboration
From Astronomy to detecting Respiratory Cilia cells
Key Findings
spectrum of symptoms, but have in common that they all lead to impaired cilia formation or...
Collaboration
Collaboration with molecular basis of disease and therapeutics
Engagement Activities
conference by Hannah Mitchison
Engagement Activities
Hannah Mitchison
Key Findings
cilia to be resorbed and identified the pathway responsible
Research Tools and Methods
We generted a number of transgenic lines (>10) to manipulate phosphoinositide content in cilia.
Collaboration
UK Cilia Network
Collaboration
Analysis of rho kinase inhibitors of ciliary function
Collaboration
Finnish PCD genetics
Collaboration
Analysis of cilia development and patterning
Key Findings
reconstruction of the beating swimming appendages (flagella) of Chlamydomonas algae. This is an...
Engagement Activities
Takeover 3 - Fraser McPhie, PhD Student
Engagement Activities
Polycystins in Chondrocyte Mechanotransuction
Collaboration
Role of primary cilia in cortical development
Engagement Activities
Takeover 2 - Dr Daniel Dodd,
Research Databases and Models
High content siRNA screen carried out to identify genes which when knocked-down, cause the...
Research Databases and Models
High content siRNA screen carried out to identify genes which when knocked-down, cause the...
Collaboration
Basal body structure and cell cycle-dependent biogenesis in Trypanosoma brucei.
Engagement Activities
and Centrosomes Meeting, Awaji, Japan
Research Tools and Methods
1) list of validated candidate genes implicated in ciliogenesis, cilia maintenance and cilia length...