Molecular assembly using gold catalysis
Lead Research Organisation:
University of St Andrews
Department Name: Chemistry
Abstract
The development of catalytic methods leading to little or no waste is an area of crucial importance in terms of energy and materials economy. The present proposal presents strategies to assemble complex molecular architectures or value-added compounds using simply synthesized organogold complexes. The proposal adopts a two-prong approach. On the one side the design and synthesis of organogold catalysts are proposed and on the other some of the catalysts already synthesized by our group and the novel ones are proposed to enable important chemical transformations. These range from hydration reactions to tandem reactions leading to multiple bond formations in a single step. The aim of the proposal is to develop useful synthetic tools, readily usable by synthetic chemists permitting facile protocols enabling the synthesis of complex molecular assemblies.
Organisations
People |
ORCID iD |
Steven Nolan (Principal Investigator) |
Publications
Nun P
(2011)
A combined mechanistic and computational study of the gold(I)-catalyzed formation of substituted indenes.
in Organic & biomolecular chemistry
Gaillard S
(2010)
A N-heterocyclic carbene gold hydroxide complex: a golden synthon.
in Chemical communications (Cambridge, England)
Fortman G
(2010)
A Versatile Cuprous Synthon: [Cu(IPr)(OH)] (IPr = 1,3 bis(diisopropylphenyl)imidazol-2-ylidene)
in Organometallics
Fortman GC
(2010)
A versatile gold synthon for acetylene C-H bond activation.
in Dalton transactions (Cambridge, England : 2003)
Ramón RS
(2010)
Au/Ag-cocatalyzed aldoximes to amides rearrangement under solvent- and acid-free conditions.
in The Journal of organic chemistry
Boogaerts II
(2010)
Carboxylation of C-H bonds using N-heterocyclic carbene gold(I) complexes.
in Journal of the American Chemical Society
Boogaerts II
(2010)
Carboxylation of N-H/C-H bonds using N-heterocyclic carbene copper(I) complexes.
in Angewandte Chemie (International ed. in English)
Fortman GC
(2011)
Catalytic deuteration of silanes mediated by N-heterocyclic carbene-Ir(III) complexes.
in Chemical communications (Cambridge, England)
Dupuy S
(2011)
Decarboxylation of aromatic carboxylic acids by gold(I)-N-heterocyclic carbene (NHC) complexes.
in Chemical communications (Cambridge, England)
Gaillard S
(2010)
Development of versatile and silver-free protocols for gold(I) catalysis.
in Chemistry (Weinheim an der Bergstrasse, Germany)