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Institute of Cancer and Genomic Sciences

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£1,321,551

Aug 19 - Dec 23

Finding therapeutic targets in FLT3-ITD AML using a systems biology approach

MRC award to University of Birmingham and Constanze Bonifer

£315,173

May 19 - Jul 23

Interrogating the relationship between tumour microenvironment and its infiltrating immune cells in high-grade serous ovarian cancer

MRC award to University of Birmingham and Rachel Pounds

£520,796

Apr 19 - Jun 20

Inactivation of the PRH/HHEX tumour suppressor and its effects on inflammatory signalling in prostate cancer.

MRC award to University of Birmingham and Padma-Sheela Jayaraman

£364,835

Mar 19 - Dec 22

Characterising novel recombination pathways at DNA adducts of the environmental mutagen BPDE

MRC award to University of Birmingham and Eva Petermann

£654,984

Mar 19 - Nov 21

Validating the PredicTR treatment response classifier for oropharyngeal cancer (PredicTR 2)

MRC award to University of Birmingham and Hisham Mehanna

£150,183

Feb 19 - Nov 20

Predicting cell-cell horizontal transmission of antibiotics resistance from genome and phenome

MRC award to University of Birmingham and Danesh Moradigaravand

£634,219

Sep 18 - Jul 22

Understanding host factors that regulate the hepatitis B viral epigenome

MRC award to University of Birmingham and Joanna Parish

Sep 18 - Sep 22

: Identification of essential genes in the innate epigenetic response to environmental agents that underpins resistance to therapeutic drugs

BBSRC award to University of Birmingham

Sep 18 - Sep 22

Using genome-wide data to model signalling-responsive gene regulatory networks

BBSRC award to University of Birmingham

Sep 18 - Apr 24

Exploring how arginine methylation impacts on DNA repair.

BBSRC award to University of Birmingham

£777,637

Sep 18 - Aug 22

UNDERSTANDING THE INTERPLAY OF ENHANCERS, CHROMATIN PRIMING ELEMENTS AND SIGNALS REGULATING DYNAMIC GENE EXPRESSION IN DEVELOPMENT

BBSRC award to University of Birmingham and Constanze Bonifer

Sep 18 - May 24

Investigating the function and regulation of UbcH10-APC/C

BBSRC award to University of Birmingham

Sep 18 - Jul 22

Exploration of the global manipulation of transcriptional networks by oncogenic

MRC award to University of Birmingham

Sep 18 - Sep 22

The implications of neural DNA damage in neurodegeneration

BBSRC award to University of Birmingham

£104,079

Sep 18 - Apr 23

Investigating the dynamic regulation of PRMT5 activity during the DNA damage response

BBSRC award to University of Birmingham

Sep 18 - Jun 22

Creating an AI based data assistant to bridge genotype to metadata - linking primary clinical data to biobank samples.

MRC award to University of Birmingham

£192,611

Jun 18 - Jan 20

Evaluation of Bayesian adaptive designs for Phase 3 effectiveness trials

MRC award to University of Birmingham and Simon Gates

£6,558,752

Apr 18 - Mar 24

A Coordinated Infrastructure for NMR in the Physical and Life Sciences: A 1 GHz Spectrometer at Birmingham

EPSRC award to University of Birmingham and Tim Softley

£359,510

Mar 18 - Sep 21

The development and assessment of a PEC based platform for the delivery of dietary iron chelators to the large bowel

BBSRC award to University of Birmingham and Chris Tselepis

£299,450

Feb 18 - Feb 21

Semantic-based secure infrastructure for interoperable, in-depth biomedical data and analytics

MRC award to University of Birmingham and Andreas Karwath

£325,589

Oct 17 - Jan 20

From single cells to populations: generalized pseudotime analysis to identify patient trajectories from cross-sectional data in cancer genomics

MRC award to University of Birmingham and Christopher Yau

£475,606

Sep 17 - Sep 20

Control of insulator function and higher order genome organisation by the chromatin remodeling enzyme NURF

BBSRC award to University of Birmingham and Paul Badenhorst

Sep 17 - Aug 21

Investigation of human papillomavirus pathogenesis in the head and neck using novel

MRC award to University of Birmingham

£241,298

Aug 17 - Feb 21

Characterisation of Chromatin Landscapes of Pre-leukaemic and Leukaemic Stem Cells in Core Binding Factor AML and their Response to Epigenetic Therapy

MRC award to University of Birmingham and Sandeep Potluri

£1,326,850

Mar 17 - Mar 23

THE IMPACT OF NON-HISTONE PROTEIN METHYLATION BY SET1A IN MAINTAINING GENOME STABILITY AND PREVENTING DISEASE

MRC award to University of Birmingham and Martin Higgs

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