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Robert Layfield

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£428,349

Aug 19 - Jul 23

Site-selective functionalisation of peptides and proteins via free-radical-induced dechalcogenation

EPSRC award to University of Nottingham and Nicholas Mitchell

Sep 17 - Sep 19

Functional interplay of p62 and TBK1- implications for autophagy in ALS

BBSRC award to University of Nottingham

Sep 15 - Sep 19

Design of bioinspired tandem ubiquitin binding domains as tools to investigate the ubiquitin-modified proteome

BBSRC award to University of Nottingham

£378,816

Jul 11 - Jan 15

Structural role of a unique p62 UBA dimer in the regulation of signal transduction and autophagy

BBSRC award to University of Nottingham and Mark Searle

£317,402

Apr 11 - Aug 13

Molecular and functional characterisation of unanchored polyubiquitin

BBSRC award to University of Nottingham and Robert Layfield

£347,609

Aug 08 - Aug 11

Probing ubiquitin topology

BBSRC award to University of Nottingham and Neil Oldham

£337,407

Apr 08 - Apr 11

Specificity in protein-ligand recognition: characterisation of a novel conformational switch in the p62 UBA domain interaction with ubiquitin

BBSRC award to University of Nottingham and Mark Searle

£185,113

Jul 06 - Jul 09

Identification of in vivo substrates of muscle atrophy-related ubiquitin ligases MAFbx and MuRF1

MRC award to University of Nottingham and Robert Layfield

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