Nanoscale quantum probing of RNA granules.

Lead Research Organisation: University of Cambridge
Department Name: Physics

Abstract

This research project aims to investigate the formation and maintenance of RNA granules, so called non-membrane compartments in which cells organise countless of their biochemical reactions, on the nanoscale. Enabled by the magneto-optical activity of stable and fluorescent point defects in nanodiamonds, highly sensitive temperature and viscosity assessment of the liquid-liquid phase separated compartments can be undertaken. The project will include various functionalisation strategies, Optically Detected Magnetic Resonance (ODMR) readouts, Atomic Force Microscopy (AFM) and Microfluidics.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/R513180/1 30/09/2018 29/09/2023
2606507 Studentship EP/R513180/1 30/09/2021 30/03/2025 Sophia Belser