Core capability for Chemistry Research
Lead Research Organisation:
Imperial College London
Department Name: Chemistry
Abstract
The National Importance of a vibrant and successful university Chemistry research sector cannot be underestimated. The RSC's report on the Economic Benefits of Chemistry showed that the UK's upstream chemicals industry and downstream chemistry-using sectors contributed a combined total of £258 billion in added-value in 2007, equivalent to 21% of UK GDP, and supported over 6 million UK jobs. This output is underpinned by some of the world's most successful University Chemistry research, reflecting the fruits of many years of investment. On-going fundamental research is essential, not only to maintain a continuing flow of scientific and technological breakthroughs, but also to ensure that the UK maintains a highly skilled and innovative workforce; it is through these trained people that the UK will adopt and advance new ideas, successfully exploit new technologies, and develop new and better products and services. The ability to develop and exploit chemically-derived technology will fuel economic activity, and is a necessary condition for attracting inward investment to the UK. The RSC report also showed that the quality of UK chemists and the reputation for excellence of the UK's university chemical science base significantly influences companies in decisions to locate within the UK, or to retain a UK-based research presence.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Planned Impact
Please see Pathways to Impact
Organisations
Publications
Furse S
(2015)
Synthesis of unsaturated phosphatidylinositol 4-phosphates and the effects of substrate unsaturation on SopB phosphatase activity.
in Organic & biomolecular chemistry
Kang DK
(2015)
3D Droplet Microfluidic Systems for High-Throughput Biological Experimentation.
in Analytical chemistry
Cao Y
(2015)
Solution Processed Bismuth Sulfide Nanowire Array Core/Silver Sulfide Shell Solar Cells
in Chemistry of Materials
Rutkowska A
(2015)
Electrodeposition and Bipolar Effects in Metallized Nanopores and Their Use in the Detection of Insulin
in Analytical Chemistry
Hu Y
(2015)
Ruthenium Dyes with Azo Ligands: Light Harvesting, Excited-State Properties and Relevance to Dye-Sensitised Solar Cells
in European Journal of Inorganic Chemistry
Casey A
(2015)
Cyano substituted benzothiadiazole: a novel acceptor inducing n-type behaviour in conjugated polymers
in Journal of Materials Chemistry C
Lawrence EJ
(2015)
A combined "electrochemical-frustrated lewis pair" approach to hydrogen activation: surface catalytic effects at platinum electrodes.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Broncel M
(2015)
Multifunctional reagents for quantitative proteome-wide analysis of protein modification in human cells and dynamic profiling of protein lipidation during vertebrate development.
in Angewandte Chemie (International ed. in English)
Windle CD
(2015)
Improving the photocatalytic reduction of CO2 to CO through immobilisation of a molecular Re catalyst on TiO2.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Pommella A
(2015)
Selective flow-induced vesicle rupture to sort by membrane mechanical properties.
in Scientific reports
O' Lee DJ
(2015)
Which way up? Recognition of homologous DNA segments in parallel and antiparallel alignments.
in The Journal of chemical physics
Zhang Y
(2015)
A coarse-grained molecular dynamics investigation of the phase behavior of DPPC/cholesterol mixtures.
in Chemistry and physics of lipids
Paul S
(2015)
Ring-opening copolymerization (ROCOP): synthesis and properties of polyesters and polycarbonates.
in Chemical communications (Cambridge, England)
MartÃnez-Ferraté O
(2015)
C-H benzylic oxidation promoted by dinuclear iron DBDOC iminopyridine complexes
in Inorganica Chimica Acta
Wright MH
(2015)
Global analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani.
in Chemistry & biology
Richardson RD
(2015)
Dual wavelength asymmetric photochemical synthesis with circularly polarized light.
in Chemical science
Crick C
(2015)
Advanced analysis of nanoparticle composites - a means toward increasing the efficiency of functional materials
in RSC Advances
Mion G
(2015)
Phototoxic Activity and DNA Interactions of Water-Soluble Porphyrins and Their Rhenium(I) Conjugates.
in ChemMedChem
Barriga HM
(2015)
Pressure-temperature phase behavior of mixtures of natural sphingomyelin and ceramide extracts.
in Langmuir : the ACS journal of surfaces and colloids
Dent MR
(2015)
Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors.
in Physical chemistry chemical physics : PCCP
Mathwig K
(2015)
Challenges of biomolecular detection at the nanoscale: nanopores and microelectrodes.
in Analytical chemistry
Fajardo OY
(2015)
Electrotunable lubricity with ionic liquid nanoscale films.
in Scientific reports
Baran D
(2015)
Role of Polymer Fractionation in Energetic Losses and Charge Carrier Lifetimes of Polymer: Fullerene Solar Cells
in The Journal of Physical Chemistry C
Hill PJ
(2015)
H2 activation by a highly electron-deficient aralkylated organoborane.
in Dalton transactions (Cambridge, England : 2003)
Cheng LJ
(2015)
Catalytic Nucleophilic Fluorination of Secondary and Tertiary Propargylic Electrophiles with a Copper-N-Heterocyclic Carbene Complex.
in Angewandte Chemie (International ed. in English)
Phanopoulos A
(2015)
The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphos Ph Complexes.
in Journal of visualized experiments : JoVE
Fallon K
(2015)
A Nature-Inspired Conjugated Polymer for High Performance Transistors and Solar Cells
in Macromolecules
Buyandelger B
(2015)
ZBTB17 ( MIZ1 ) Is Important for the Cardiac Stress Response and a Novel Candidate Gene for Cardiomyopathy and Heart Failure
in Circulation: Cardiovascular Genetics
He Y
(2015)
Dynamic Charge Storage in Ionic Liquids-Filled Nanopores: Insight from a Computational Cyclic Voltammetry Study.
in The journal of physical chemistry letters
Thompson AJ
(2015)
Molecular Rotors Provide Insights into Microscopic Structural Changes During Protein Aggregation.
in The journal of physical chemistry. B
Bull J
(2015)
Recent Advances in the Synthesis of 2-Substituted Oxetanes
in Synlett
Carroll L
(2015)
Mn-salen catalysed benzylic C-H activation for the synthesis of aryl [(18)F]CF3-containing PET probes.
in Chemical communications (Cambridge, England)
Pitchford WH
(2015)
Synchronized optical and electronic detection of biomolecules using a low noise nanopore platform.
in ACS nano
Markiewicz M
(2015)
Performance measurements and modelling of the ORR on fuel cell electrocatalysts - the modified double trap model
in Electrochimica Acta
Sim A
(2015)
Great cities look small
in Journal of The Royal Society Interface
Karamdad K
(2015)
Preparation and mechanical characterisation of giant unilamellar vesicles by a microfluidic method.
in Lab on a chip
Shivalingam A
(2015)
The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy.
in Nature communications
Madej BD
(2015)
A Parameterization of Cholesterol for Mixed Lipid Bilayer Simulation within the Amber Lipid14 Force Field.
in The journal of physical chemistry. B
Demetriadou A
(2015)
Principles of nanoparticle imaging using surface plasmons
in New Journal of Physics
Gomes H
(2015)
All-inkjet printed organic transistors: Dielectric surface passivation techniques for improved operational stability and lifetime
in Microelectronics Reliability
Barreiro E
(2015)
HBF4-Catalysed Nucleophilic Substitutions of Propargylic Alcohols.
in European journal of organic chemistry
De Luca F
(2015)
Nacre-nanomimetics: Strong, Stiff, and Plastic.
in ACS applied materials & interfaces
Boultwood T
(2015)
Studies on the synthesis of a-iodoaziridines and improved conditions for the synthesis of alkyl-a-iodoaziridines using ClMgCHI2
in Tetrahedron
Fei Z
(2015)
Diselenogermole as a novel donor monomer for low band gap polymers
in Journal of Materials Chemistry A
Giovannitti A
(2015)
Sodium and Potassium Ion Selective Conjugated Polymers for Optical Ion Detection in Solution and Solid State
in Advanced Functional Materials
Nako AE
(2015)
Bis(s-B-H) complexes of copper(i): precursors to a heterogeneous amine-borane dehydrogenation catalyst.
in Dalton transactions (Cambridge, England : 2003)
McCarthy NL
(2015)
Separation of liquid domains in model membranes induced with high hydrostatic pressure.
in Chemical communications (Cambridge, England)
| Description | Chemistry is the study and application of the science at the molecular scale. It provides some of the most basic understandings of how the world works and underpins many modern technologies. It provides both the most mundane of objects, such as the disposable cup that holds you coffee, and the most vital compounds, such as life-saving drugs. Chemistry relies on four core instrumental techniques to study molecules; Nuclear Magnetic Resonance, Mass Spectrometry, X-Ray Crystallography and molecular scale Microscopy. This grant gave the Chemistry Department at Imperial College the ability to update these facilities. These have enabled research in all areas of Chemistry, for example the building of artificial cells, the production of fuels from biomass to the development of new potential pharmaceuticals and diagnostic techniques. There are too many to list. |
| Exploitation Route | There are many ways in which these results can be put to use in the wider world. |
| Sectors | Aerospace Defence and Marine Agriculture Food and Drink Chemicals Energy Environment Healthcare Manufacturing including Industrial Biotechology Culture Heritage Museums and Collections Pharmaceuticals and Medical Biotechnology Security and Diplomacy Transport |
| Description | Policy Briefing Document |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Author of policy briefing document: Using Carbon Dioxide |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation to stakeholders |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Laura Barter was invited to the World Economic Forum in Davos to present her research investigating methods for increasing crop yields by promoting more efficient photosynthesis in the session on "Engineering Intelligent Food Systems". |
| Year(s) Of Engagement Activity | 2018 |
| Description | Radio Interview |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Andrew Ashley interviewed on BBC Radio 4's Inside Science explaining his group's recent discovery in N2 fixation |
| Year(s) Of Engagement Activity | 2016 |
| Description | Radio Interview |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | BBC World Service's The Why Factor (8 February) on "Why is Water Exceptional?" |
| Year(s) Of Engagement Activity | 2016 |
| Description | Schools activity |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Salters Festival of Chemistry: Annual Salters Festival. Y7 and Y8 many schools attend with their teachers to undertake two chemistry-based challenges |
| Year(s) Of Engagement Activity | 2018 |
| Description | Stakeholder meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Laura Barter, Rudiger Wolcholski and Sarah Al-Beidh organised a Creativity and Ideas generation event for the Sainsbury's farming scholars which was also attended by Sainsbury's horticulture manager, academics from Imperial, Natural History Museum and other UK institutions. Followed by attending the Annual Sainsbury's Farming Conference to highlight the success of the Sainsbury's Farming Scholars Programme - a recent collaboration between Imperial College, AGRI-net and Sainsbury's. |
| Year(s) Of Engagement Activity | 2015,2016 |
| Description | UK Chemicals Stakeholder Forum. Presentation on measuring sustainability |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Presentation and discussion on sustainability metrics |
| Year(s) Of Engagement Activity | 2016 |
| Description | World Economic Forum meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Prof David Klug introduced the "Hyperconnected Healthcare" panel at the World Economic Forum meeting in Dalian and participated as a panel member. |
| Year(s) Of Engagement Activity | 2015 |