Core capability for Chemistry Research
Lead Research Organisation:
Imperial College London
Department Name: Chemistry
Abstract
The National Importance of a vibrant and successful university Chemistry research sector cannot be underestimated. The RSC's report on the Economic Benefits of Chemistry showed that the UK's upstream chemicals industry and downstream chemistry-using sectors contributed a combined total of £258 billion in added-value in 2007, equivalent to 21% of UK GDP, and supported over 6 million UK jobs. This output is underpinned by some of the world's most successful University Chemistry research, reflecting the fruits of many years of investment. On-going fundamental research is essential, not only to maintain a continuing flow of scientific and technological breakthroughs, but also to ensure that the UK maintains a highly skilled and innovative workforce; it is through these trained people that the UK will adopt and advance new ideas, successfully exploit new technologies, and develop new and better products and services. The ability to develop and exploit chemically-derived technology will fuel economic activity, and is a necessary condition for attracting inward investment to the UK. The RSC report also showed that the quality of UK chemists and the reputation for excellence of the UK's university chemical science base significantly influences companies in decisions to locate within the UK, or to retain a UK-based research presence.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Planned Impact
Please see Pathways to Impact
Organisations
Publications
Deledalle F
(2014)
Understanding the Apparent Charge Density Dependence of Mobility and Lifetime in Organic Bulk Heterojunction Solar Cells
in The Journal of Physical Chemistry C
Bresme F
(2014)
Communication: minimum in the thermal conductivity of supercooled water: a computer simulation study.
in The Journal of chemical physics
Berger RJ
(2014)
Gold(I) mediated rearrangement of [7]-helicene to give a benzo[cd]pyrenium cation embedded in a chiral framework.
in Chemical communications (Cambridge, England)
Bruno A
(2014)
Ternary hybrid systems of P3HT-CdSe-WS2 nanotubes for photovoltaic applications.
in Physical chemistry chemical physics : PCCP
Krausbeck F
(2014)
Choosing RASSCF orbital active spaces for multiple electronic states
in Computational and Theoretical Chemistry
Pisaneschi F
(2014)
Synthesis of a new fluorine-18 glycosylated 'click' cyanoquinoline for the imaging of epidermal growth factor receptor.
in Journal of labelled compounds & radiopharmaceuticals
Wann D
(2014)
Structures of Tetrasilylmethane Derivatives C(SiXMe 2 ) 4 (X=H, F, Cl, Br) in the Gas Phase and their Dynamic Structures in Solution
in Zeitschrift für Naturforschung B
Sung S
(2014)
Multimetallic complexes and functionalized gold nanoparticles based on a combination of d- and f-elements.
in Inorganic chemistry
Barrett T
(2014)
Cascade Polyketide and Polyene Cyclizations: Biomimetic Total Synthesis of Hongoquercin B
in Journal of the American Chemical Society
Ekkert O
(2014)
Rhodium Catalyzed, Carbon-Hydrogen Bond Directed Hydrodefluorination of Fluoroarenes
in Organometallics
Moreira F
(2014)
Protein-responsive polymers for point-of-care detection of cardiac biomarker
in Sensors and Actuators B: Chemical
Barriga HM
(2014)
Droplet interface bilayer reconstitution and activity measurement of the mechanosensitive channel of large conductance from Escherichia coli.
in Journal of the Royal Society, Interface
Carreras P
(2014)
Microfluidic generation of droplet interface bilayer networks incorporating real-time size sorting in linear and non-linear configurations.
in Biomicrofluidics
Armstrong A
(2014)
Tertiary amine-promoted enone aziridination: investigations into factors influencing enantioselective induction
in Tetrahedron: Asymmetry
Boultwood T
(2014)
Stereospecific functionalization of iodoaziridines via unstabilized aziridinyllithiums generated by iodine-lithium exchange.
in Organic letters
Beatrup D
(2014)
Polaron stability in semiconducting polymer neat films.
in Chemical communications (Cambridge, England)
Grau M
(2014)
Ligand tuning of single-site manganese-based catalytic antioxidants with dual superoxide dismutase and catalase activity.
in Chemical communications (Cambridge, England)
Brooks N
(2014)
High Pressure X-ray Studies of Lipid Membranes and Lipid Phase Transitions
in Zeitschrift für Physikalische Chemie
Haywood T
(2014)
Microfluidic Hydrogenation Reactions by using a Channel-Supported Rhodium Catalyst
in ChemCatChem
Credgington D
(2014)
In Situ Measurement of Energy Level Shifts and Recombination Rates in Subphthalocyanine/C 60 Bilayer Solar Cells
in The Journal of Physical Chemistry C
Ghosh S
(2014)
Assembly of palladium(II) and platinum(II) metallo-rectangles with a guanosine-substituted terpyridine and study of their interactions with quadruplex DNA.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Braddock DC
(2014)
Proof-of-principle direct double cyclisation of a linear C15-precursor to a dibrominated bicyclic medium-ring ether relevant to Laurencia species.
in Chemical communications (Cambridge, England)
Cecchini M
(2014)
Heavy Metal Sensing Using Self-Assembled Nanoparticles at a Liquid-Liquid Interface
in Advanced Optical Materials
Elani Y
(2014)
Vesicle-based artificial cells as chemical microreactors with spatially segregated reaction pathways.
in Nature communications
Murray JI
(2014)
Highly efficient and selective phosphorylation of amino acid derivatives and polyols catalysed by 2-aryl-4-(dimethylamino)pyridine-N-oxides--towards kinase-like reactivity.
in Chemical communications (Cambridge, England)
Thinon E
(2014)
Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.
in Nature communications
Ekkert O
(2015)
Addition of aluminium, zinc and magnesium hydrides to rhodium(iii).
in Chemical science
Spivey A
(2015)
Organocatalytic Phosphorylation of Alcohols Using Pyridine-N-oxide
in Synlett
De Luca F
(2015)
Nacre-nanomimetics: Strong, Stiff, and Plastic
in ACS Applied Materials & Interfaces
Bolognesi G
(2015)
Microfluidic generation of monodisperse ultra-low interfacial tension oil droplets in water
in RSC Advances
Nako AE
(2015)
Bis(s-B-H) complexes of copper(i): precursors to a heterogeneous amine-borane dehydrogenation catalyst.
in Dalton transactions (Cambridge, England : 2003)
Meisner J
(2015)
Geometric Rotation of the Nuclear Gradient at a Conical Intersection: Extension to Complex Rotation of Diabatic States.
in Journal of chemical theory and computation
Fei Z
(2015)
Influence of Backbone Fluorination in Regioregular Poly(3-alkyl-4-fluoro)thiophenes
in Journal of the American Chemical Society
Mion G
(2015)
Phototoxic Activity and DNA Interactions of Water-Soluble Porphyrins and Their Rhenium(I) Conjugates.
in ChemMedChem
Rochester C
(2015)
Statistical Mechanics of 'Unwanted Electroactuation' in Nanoporous Supercapacitors
in Electrochimica Acta
Karamdad K
(2015)
Preparation and mechanical characterisation of giant unilamellar vesicles by a microfluidic method.
in Lab on a chip
Nallapan Maniyam M
(2015)
Enzymatic cyanide degradation by cell-free extract of Rhodococcus UKMP-5M.
in Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
Phanopoulos A
(2015)
Beyond Triphos - New hinges for a classical chelating ligand
in Coordination Chemistry Reviews
Dent MR
(2015)
Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors.
in Physical chemistry chemical physics : PCCP
Bakewell C
(2015)
Comparing a series of 8-quinolinolato complexes of aluminium, titanium and zinc as initiators for the ring-opening polymerization of rac-lactide.
in Dalton transactions (Cambridge, England : 2003)
Madej BD
(2015)
A Parameterization of Cholesterol for Mixed Lipid Bilayer Simulation within the Amber Lipid14 Force Field.
in The journal of physical chemistry. B
Scott DJ
(2015)
Facile Protocol for Water-Tolerant "Frustrated Lewis Pair"-Catalyzed Hydrogenation.
in ACS catalysis
Sim A
(2015)
Great cities look small.
in Journal of the Royal Society, Interface
Zhang Y
(2015)
A coarse-grained molecular dynamics investigation of the phase behavior of DPPC/cholesterol mixtures
in Chemistry and Physics of Lipids
Phanopoulos A
(2015)
Catalytic Transformation of Levulinic Acid to 2-Methyltetrahydrofuran Using Ruthenium- N -Triphos Complexes
in ACS Catalysis
Sun Y
(2015)
Field-assisted self-assembly process: general discussion.
in Faraday discussions
Hill PJ
(2015)
H2 activation by a highly electron-deficient aralkylated organoborane.
in Dalton transactions (Cambridge, England : 2003)
Neri G
(2015)
A functionalised nickel cyclam catalyst for CO2 reduction: electrocatalysis, semiconductor surface immobilisation and light-driven electron transfer.
in Physical chemistry chemical physics : PCCP
Description | Chemistry is the study and application of the science at the molecular scale. It provides some of the most basic understandings of how the world works and underpins many modern technologies. It provides both the most mundane of objects, such as the disposable cup that holds you coffee, and the most vital compounds, such as life-saving drugs. Chemistry relies on four core instrumental techniques to study molecules; Nuclear Magnetic Resonance, Mass Spectrometry, X-Ray Crystallography and molecular scale Microscopy. This grant gave the Chemistry Department at Imperial College the ability to update these facilities. These have enabled research in all areas of Chemistry, for example the building of artificial cells, the production of fuels from biomass to the development of new potential pharmaceuticals and diagnostic techniques. There are too many to list. |
Exploitation Route | There are many ways in which these results can be put to use in the wider world. |
Sectors | Aerospace, Defence and Marine,Agriculture, Food and Drink,Chemicals,Energy,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Culture, Heritage, Museums and Collections,Pharmaceuticals and Medical Biotechnology,Security and Diplomacy,Transport |
Description | Policy Briefing Document |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Author of policy briefing document: Using Carbon Dioxide |
Year(s) Of Engagement Activity | 2017 |
Description | Presentation to stakeholders |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Laura Barter was invited to the World Economic Forum in Davos to present her research investigating methods for increasing crop yields by promoting more efficient photosynthesis in the session on "Engineering Intelligent Food Systems". |
Year(s) Of Engagement Activity | 2018 |
Description | Radio Interview |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | BBC World Service's The Why Factor (8 February) on "Why is Water Exceptional?" |
Year(s) Of Engagement Activity | 2016 |
Description | Radio Interview |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Andrew Ashley interviewed on BBC Radio 4's Inside Science explaining his group's recent discovery in N2 fixation |
Year(s) Of Engagement Activity | 2016 |
Description | Schools activity |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Schools |
Results and Impact | Salters Festival of Chemistry: Annual Salters Festival. Y7 and Y8 many schools attend with their teachers to undertake two chemistry-based challenges |
Year(s) Of Engagement Activity | 2018 |
Description | Stakeholder meeting |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Laura Barter, Rudiger Wolcholski and Sarah Al-Beidh organised a Creativity and Ideas generation event for the Sainsbury's farming scholars which was also attended by Sainsbury's horticulture manager, academics from Imperial, Natural History Museum and other UK institutions. Followed by attending the Annual Sainsbury's Farming Conference to highlight the success of the Sainsbury's Farming Scholars Programme - a recent collaboration between Imperial College, AGRI-net and Sainsbury's. |
Year(s) Of Engagement Activity | 2015,2016 |
Description | UK Chemicals Stakeholder Forum. Presentation on measuring sustainability |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Policymakers/politicians |
Results and Impact | Presentation and discussion on sustainability metrics |
Year(s) Of Engagement Activity | 2016 |
Description | World Economic Forum meeting |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Prof David Klug introduced the "Hyperconnected Healthcare" panel at the World Economic Forum meeting in Dalian and participated as a panel member. |
Year(s) Of Engagement Activity | 2015 |