Core capability for Chemistry Research
Lead Research Organisation:
Imperial College London
Department Name: Chemistry
Abstract
The National Importance of a vibrant and successful university Chemistry research sector cannot be underestimated. The RSC's report on the Economic Benefits of Chemistry showed that the UK's upstream chemicals industry and downstream chemistry-using sectors contributed a combined total of £258 billion in added-value in 2007, equivalent to 21% of UK GDP, and supported over 6 million UK jobs. This output is underpinned by some of the world's most successful University Chemistry research, reflecting the fruits of many years of investment. On-going fundamental research is essential, not only to maintain a continuing flow of scientific and technological breakthroughs, but also to ensure that the UK maintains a highly skilled and innovative workforce; it is through these trained people that the UK will adopt and advance new ideas, successfully exploit new technologies, and develop new and better products and services. The ability to develop and exploit chemically-derived technology will fuel economic activity, and is a necessary condition for attracting inward investment to the UK. The RSC report also showed that the quality of UK chemists and the reputation for excellence of the UK's university chemical science base significantly influences companies in decisions to locate within the UK, or to retain a UK-based research presence.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Planned Impact
Please see Pathways to Impact
Organisations
Publications
McDonald C
(2015)
Membrane Stored Curvature Elastic Stress Modulates Recruitment of Maintenance Proteins PspA and Vipp1.
in mBio
Fei Z
(2015)
Influence of Backbone Fluorination in Regioregular Poly(3-alkyl-4-fluoro)thiophenes.
in Journal of the American Chemical Society
Villar-Garcia IJ
(2015)
Fine tuning the ionic liquid-vacuum outer atomic surface using ion mixtures.
in Chemical communications (Cambridge, England)
Celaya-Sanfiz A
(2015)
Self-condensation of acetone over Mg-Al layered double hydroxide supported on multi-walled carbon nanotube catalysts
in Journal of Molecular Catalysis A: Chemical
Anwar A
(2015)
Abstracts of the 23rd International Isotope Society (UK group) Symposium: synthesis and applications of labelled compounds 2014 IIS_UK_2014
in Journal of Labelled Compounds and Radiopharmaceuticals
Mohammad-Aghaie D
(2015)
Force-field dependence on the liquid-expanded to liquid-condensed transition in DPPC monolayers
in Molecular Simulation
Allen C
(2015)
Efficient and Facile Synthesis of Acrylamide Libraries for Protein-Guided Tethering
in Organic Letters
Vigor WA
(2015)
Minimising biases in full configuration interaction quantum Monte Carlo.
in The Journal of chemical physics
Sun Y
(2015)
Field-assisted self-assembly process: general discussion.
in Faraday discussions
Britovsek G
(2015)
Single- and Double-Coordination Mechanism in Ethylene Tri- and Tetramerization with Cr/PNP Catalysts
in ACS Catalysis
Shoaee S
(2015)
A Comparison of Charge Separation Dynamics in Organic Blend Films Employing Fullerene and Perylene Diimide Electron Acceptors.
in The journal of physical chemistry letters
Palomas D
(2015)
Re-evaluating selectivity as a determining factor in peroxidative methane oxidation by multimetallic copper complexes
in Catalysis Science & Technology
Bolognesi G
(2015)
Microfluidic generation of monodisperse ultra-low interfacial tension oil droplets in water
in RSC Advances
Clough M
(2015)
Ionic liquids: not always innocent solvents for cellulose
in Green Chemistry
Elani Y
(2015)
Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors.
in Physical chemistry chemical physics : PCCP
Scott DJ
(2015)
Facile Protocol for Water-Tolerant "Frustrated Lewis Pair"-Catalyzed Hydrogenation.
in ACS catalysis
Armstrong A
(2015)
Tertiary Amine Promoted Aziridination: Preparation of NH-Aziridines from Aliphatic a,ß-Unsaturated Ketones
in Synlett
Bull J
(2015)
2-Sulfinyl Oxetanes: Synthesis, Stability and Reactivity
in Synlett
Yue W
(2015)
A thieno[3,2-b][1]benzothiophene isoindigo building block for additive- and annealing-free high-performance polymer solar cells.
in Advanced materials (Deerfield Beach, Fla.)
Wood S
(2015)
Natures of optical absorption transitions and excitation energy dependent photostability of diketopyrrolopyrrole (DPP)-based photovoltaic copolymers
in Energy & Environmental Science
Winkler M
(2015)
Renewable polycarbonates and polyesters from 1,4-cyclohexadiene
in Green Chemistry
Andernach R
(2015)
Synthesis and Exciton Dynamics of Triplet Sensitized Conjugated Polymers.
in Journal of the American Chemical Society
Yeh JS
(2015)
Quantitative ultrasound molecular imaging.
in Ultrasound in medicine & biology
Cooper RT
(2015)
Double CO2 activation by 14-electron ?(8)-permethylpentalene titanium dialkyl complexes.
in Chemical communications (Cambridge, England)
Ivanov AP
(2015)
On-demand delivery of single DNA molecules using nanopipets.
in ACS nano
Carreras P
(2015)
A microfluidic platform for size-dependent generation of droplet interface bilayer networks on rails.
in Biomicrofluidics
Elani Y
(2015)
Vesicle-based artificial cells: recent developments and prospects for drug delivery.
in Therapeutic delivery
Ekkert O
(2015)
Addition of aluminium, zinc and magnesium hydrides to rhodium(iii).
in Chemical science
Udemba A
(2015)
Design, synthesis and initial characterisation of a radiolabelled [(18)F]pyrimidoindolone probe for detecting activated caspase-3/7.
in Organic & biomolecular chemistry
Izquierdo MA
(2015)
Dual use of porphyrazines as sensitizers and viscosity markers in photodynamic therapy.
in Journal of materials chemistry. B
Sze JY
(2015)
Fine tuning of nanopipettes using atomic layer deposition for single molecule sensing.
in The Analyst
Tang H
(2015)
Glass polyalkenoate cements based on simple CaO-Al 2 O 3 -SiO 2 glasses
in Materials Science and Technology
Billcliff PG
(2016)
OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates.
in Molecular biology of the cell
Freedman KJ
(2016)
Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping.
in Nature communications
Ang DL
(2016)
Quadruplex DNA-Stabilising Dinuclear Platinum(II) Terpyridine Complexes with Flexible Linkers.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Bayazit MK
(2016)
Carbon nanotube anions for the preparation of gold nanoparticle-nanocarbon hybrids.
in Chemical communications (Cambridge, England)
Barriga HM
(2016)
The effect of hydrostatic pressure on model membrane domain composition and lateral compressibility.
in Physical chemistry chemical physics : PCCP
Chen S
(2016)
Avoiding artefacts during electron microscopy of silver nanomaterials exposed to biological environments.
in Journal of microscopy
Verrastro I
(2016)
Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins.
in Free radical biology & medicine
Cappel U
(2016)
Evidence for photo-induced charge separation between dye molecules adsorbed to aluminium oxide surfaces
in Scientific Reports
Ding S
(2016)
In situ, high-resolution evidence for iron-coupled mobilization of phosphorus in sediments.
in Scientific reports
Matthews RP
(2016)
A structural investigation of ionic liquid mixtures.
in Physical chemistry chemical physics : PCCP
Kumar S
(2016)
Template-Stripped Multifunctional Wedge and Pyramid Arrays for Magnetic Nanofocusing and Optical Sensing.
in ACS applied materials & interfaces
De La Calle Arregui C
(2016)
Optimised conditions for the synthesis of (17)O and (18)O labelled cholesterol.
in Chemistry and physics of lipids
Burés J
(2016)
A Simple Graphical Method to Determine the Order in Catalyst.
in Angewandte Chemie (International ed. in English)
Dimitrov SD
(2016)
Singlet Exciton Lifetimes in Conjugated Polymer Films for Organic Solar Cells.
in Polymers
Martin HP
(2016)
Microfluidic processing of concentrated surfactant mixtures: online SAXS, microscopy and rheology.
in Soft matter
Govada L
(2016)
Exploring Carbon Nanomaterial Diversity for Nucleation of Protein Crystals.
in Scientific reports
| Description | Chemistry is the study and application of the science at the molecular scale. It provides some of the most basic understandings of how the world works and underpins many modern technologies. It provides both the most mundane of objects, such as the disposable cup that holds you coffee, and the most vital compounds, such as life-saving drugs. Chemistry relies on four core instrumental techniques to study molecules; Nuclear Magnetic Resonance, Mass Spectrometry, X-Ray Crystallography and molecular scale Microscopy. This grant gave the Chemistry Department at Imperial College the ability to update these facilities. These have enabled research in all areas of Chemistry, for example the building of artificial cells, the production of fuels from biomass to the development of new potential pharmaceuticals and diagnostic techniques. There are too many to list. |
| Exploitation Route | There are many ways in which these results can be put to use in the wider world. |
| Sectors | Aerospace Defence and Marine Agriculture Food and Drink Chemicals Energy Environment Healthcare Manufacturing including Industrial Biotechology Culture Heritage Museums and Collections Pharmaceuticals and Medical Biotechnology Security and Diplomacy Transport |
| Description | Policy Briefing Document |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Author of policy briefing document: Using Carbon Dioxide |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation to stakeholders |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Laura Barter was invited to the World Economic Forum in Davos to present her research investigating methods for increasing crop yields by promoting more efficient photosynthesis in the session on "Engineering Intelligent Food Systems". |
| Year(s) Of Engagement Activity | 2018 |
| Description | Radio Interview |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Andrew Ashley interviewed on BBC Radio 4's Inside Science explaining his group's recent discovery in N2 fixation |
| Year(s) Of Engagement Activity | 2016 |
| Description | Radio Interview |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | BBC World Service's The Why Factor (8 February) on "Why is Water Exceptional?" |
| Year(s) Of Engagement Activity | 2016 |
| Description | Schools activity |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Salters Festival of Chemistry: Annual Salters Festival. Y7 and Y8 many schools attend with their teachers to undertake two chemistry-based challenges |
| Year(s) Of Engagement Activity | 2018 |
| Description | Stakeholder meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Laura Barter, Rudiger Wolcholski and Sarah Al-Beidh organised a Creativity and Ideas generation event for the Sainsbury's farming scholars which was also attended by Sainsbury's horticulture manager, academics from Imperial, Natural History Museum and other UK institutions. Followed by attending the Annual Sainsbury's Farming Conference to highlight the success of the Sainsbury's Farming Scholars Programme - a recent collaboration between Imperial College, AGRI-net and Sainsbury's. |
| Year(s) Of Engagement Activity | 2015,2016 |
| Description | UK Chemicals Stakeholder Forum. Presentation on measuring sustainability |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Presentation and discussion on sustainability metrics |
| Year(s) Of Engagement Activity | 2016 |
| Description | World Economic Forum meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Prof David Klug introduced the "Hyperconnected Healthcare" panel at the World Economic Forum meeting in Dalian and participated as a panel member. |
| Year(s) Of Engagement Activity | 2015 |