Enhanced interpretation of metabolomics data to accelerate microbial engineering.
Lead Participant:
INGENZA LIMITED
Abstract
This project addresses a current severe limitation in the successful industrial use of engineered microbes,
namely to rapidly achieve predictable, iterative improvements in productivity to establish competitive process
economics. It combines software engineering, bioinformatics, metabolomics and high-throughput construction
of recombinant bacteria and yeast, to implement a system that will accelerate the development of engineered
strains for next generation biosynthesis of fuel, chemicals and polymer products, manufactured from
sustainable feedstocks. The project will combine the strengths of a leading UK Industrial Biotechnology SME
and a state of the art university Polyomics facility to demonstrate a step change in the UK’s capability to
develop new industrial bioprocesses.
namely to rapidly achieve predictable, iterative improvements in productivity to establish competitive process
economics. It combines software engineering, bioinformatics, metabolomics and high-throughput construction
of recombinant bacteria and yeast, to implement a system that will accelerate the development of engineered
strains for next generation biosynthesis of fuel, chemicals and polymer products, manufactured from
sustainable feedstocks. The project will combine the strengths of a leading UK Industrial Biotechnology SME
and a state of the art university Polyomics facility to demonstrate a step change in the UK’s capability to
develop new industrial bioprocesses.
Lead Participant | Project Cost | Grant Offer |
---|---|---|
INGENZA LIMITED | £279,859 | £ 195,901 |
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Participant |
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UNIVERSITY OF GLASGOW | £119,836 | £ 119,836 |
INNOVATE UK |
People |
ORCID iD |