Defining the Contribution of Dorsal Vagal Complex Astrocytes to the Regulation of Food Intake
Lead Research Organisation:
University of Exeter
Department Name: University of Exeter Medical School
Abstract
Dysregulation of food intake contributes to obesity, a major health issue in the UK. The brain regulates food intake by integrating nutritional, nervous and hormonal cues. Utilizing an integrative physiological approach this project will focus on understanding of the contribution of glia to the neural circuits that regulate food intake.
Organisations
Publications
MacDonald A
(2019)
Astrocytes in neuroendocrine systems: An overview
in Journal of Neuroendocrinology
MacDonald AJ
(2020)
Astrocytes in the nucleus of the solitary tract: Contributions to neural circuits controlling physiology.
in Physiology & behavior
MacDonald AJ
(2020)
Regulation of food intake by astrocytes in the brainstem dorsal vagal complex.
in Glia
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| MR/N013794/1 | 01/10/2016 | 30/09/2025 | |||
| 1789781 | Studentship | MR/N013794/1 | 01/10/2016 | 31/03/2020 | Alastair MacDonald |
| Description | Conference Presentation: Society for the Study of Ingestive Behavior Annual Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Abstract was selected for an oral communication at this conference. Gave a 12 minute presentation followed by questions from scientists in the field. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited Talk - Physiology of Obesity and Diabetes Symposium Aberdeen 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | An invited research presentation on the role of hindbrain astrocytes in regulating feeding behaviour at the a satellite symposium from the main annual Physiological Society meeting. The symposium was focused on the physiology of obesity and diabetes. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.physoc.org/events/physiology-obesity-diabetes/ |
| Description | Invited plenary speaker - ESR event for British Society for Neuroendocrinology |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A plenary presentation on astrocytes and the regulation of energy homeostasis at the British Society for Neuroendocrinology Early Career Symposium in Glasgow in December 2019. This event was attended by early career members of the society as week and more senior members. There were about 60 people in attendance. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.neuroendo.org.uk/page.php?item_name=EVENT%3A+Neuroendo+Celebrate |