Removal of antimicrobial resistance genes from bacterial strains and communities using CRISPR-Cas9.
Lead Research Organisation:
UNIVERSITY OF EXETER
Department Name: University of Exeter Medical School
Abstract
Antimicrobial resistance (AMR) is one of the greatest threats to human health of our time and discovering ways to prevent the spread of AMR would be truly ground breaking. This develops the CRISPR-Cas9 genome editing system to target and destroy AMR genes in complex microbial communities present in the lungs of cystic fibrosis patients.
Organisations
People |
ORCID iD |
William Gaze (Primary Supervisor) | |
David Walker-Sünderhauf (Student) |
Publications
Pursey E
(2018)
CRISPR-Cas antimicrobials: Challenges and future prospects.
in PLoS pathogens
Description | Junior Scientist Conference Grant, non-GS Meeting |
Amount | £460 (GBP) |
Organisation | The Genetics Society |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2019 |
End | 07/2019 |
Description | Microbiology Society Travel Grant |
Amount | £240 (GBP) |
Organisation | Microbiology Society |
Sector | Learned Society |
Country | United Kingdom |
Start | 02/2020 |
End | 02/2020 |
Description | Stall at Royal Cornwall Show |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | Royal Cornwall Show (Wadebridge, June 2019). I designed a hands-on science activity centred on antibiotic resistance and the environment and led a team delivering this at the three-day Royal Cornwall Show |
Year(s) Of Engagement Activity | 2019 |
URL | https://vanhoutelab.wordpress.com/2019/06/10/royal-cornwall-show/ |