Tools and technologies for engineering self-regulated nitrogen fixation in plant-associated bacteria
Lead Research Organisation:
Imperial College London
Department Name: Bioengineering
Abstract
One major challenge in synthetic biology is that programming bacteria to perform extra tasks can put a significant burden on them, typically leading to decreased cell fitness and performance. This is especially relevant for applications in highly complex environments (e.g. the plant rhizosphere), where engineered bacteria are likely to be at a severe competitive disadvantage.
In this project we will apply a combined synthetic biology and control engineering approach to tackle the competitive disadvantage of recombinant nitrogen-fixing bacteria in the soil-plant environment, with the ultimate goal of developing more robust nitrogen-fixing inoculants for sustainable agriculture.
In this project we will apply a combined synthetic biology and control engineering approach to tackle the competitive disadvantage of recombinant nitrogen-fixing bacteria in the soil-plant environment, with the ultimate goal of developing more robust nitrogen-fixing inoculants for sustainable agriculture.
Organisations
People |
ORCID iD |
Guy-Bart Stan (Primary Supervisor) | |
Albert Fabregas Flavia (Student) |
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/R513052/1 | 01/10/2018 | 30/09/2023 | |||
2295850 | Studentship | EP/R513052/1 | 01/12/2019 | 30/08/2023 | Albert Fabregas Flavia |
EP/T51780X/1 | 01/10/2020 | 30/09/2025 | |||
2295850 | Studentship | EP/T51780X/1 | 01/12/2019 | 30/08/2023 | Albert Fabregas Flavia |