Methodology for the characterisation of aggregation mechanisms in proteins

Lead Research Organisation: University of Warwick
Department Name: Chemistry


The aim of the PhD project is to develop a biological and characterisation toolbox using NMR spectroscopy (both solution and solid-state NMR) and cryo-EM to probe protein-protein or protein-excipient intermolecular interactions, at resolution scales ranging from low resolution analysis providing domain/region conformational changes to atomic resolution providing site specific interactions, in order to understand the mechanisms of protein aggregation.


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Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/V50967X/1 30/09/2020 29/09/2024
2433673 Studentship BB/V50967X/1 04/10/2020 29/09/2024 Jack Drant