US - Phylogenetic approaches to network analysis.
Lead Research Organisation:
Imperial College London
Department Name: Life Sciences
Abstract
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People |
ORCID iD |
| John Pinney (Principal Investigator) |
| Description | This funding has supported the development of advanced methods for the study of the evolution of cellular systems, in particular how interactions between proteins can be related to each other via the duplication and subsequent divergence of genes. |
| Exploitation Route | Our methods will be of use in the field of evolutionary systems biology and for extrapolating results obtained from model organisms to other species. |
| Sectors | Manufacturing including Industrial Biotechology Pharmaceuticals and Medical Biotechnology |
| Description | No economic or social impact as yet. |
| Description | Signaling pathway collaboration |
| Organisation | Carnegie Mellon University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Bioinformatics methods for investigating evolution of protein-protein interactions. |
| Collaborator Contribution | Algorithms for analysing complex evolutionary histories on trees (Carnegie Mellon) and experimental genetics study of protein-protein interactions (MIT). |
| Impact | Successful application to HFSP for programme grant to study evolution of two-component signaling systems in bacteria. Initial phylogenetic studies on Spo signaling pathway nearing completion. |
| Start Year | 2013 |
| Description | Signaling pathway collaboration |
| Organisation | Massachusetts Institute of Technology |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Bioinformatics methods for investigating evolution of protein-protein interactions. |
| Collaborator Contribution | Algorithms for analysing complex evolutionary histories on trees (Carnegie Mellon) and experimental genetics study of protein-protein interactions (MIT). |
| Impact | Successful application to HFSP for programme grant to study evolution of two-component signaling systems in bacteria. Initial phylogenetic studies on Spo signaling pathway nearing completion. |
| Start Year | 2013 |