Modelling hormonal crosstalk - commonalities between bacterial and fungal resistance and susceptibility networks.

Lead Research Organisation: University of Exeter
Department Name: Biosciences


Description A role for a jasmonic acid repressor, JAZ7, in resistance to the wheat patohgen Fusarium.
Exploitation Route CSIRO are following up the JAZ7 story to understand the underlying mechanisms.
New publication now out - added above
Sectors Agriculture, Food and Drink

Description Understanding the mechanism of chloroplast immunity
Amount £510,096 (GBP)
Funding ID BB/P002560/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 03/2017 
End 03/2020
Description Structural elucidation 
Organisation University of Queensland
Country Australia 
Sector Academic/University 
PI Contribution The travel award enabled the PI to meet ad initiate a collaboration with one of the world leading structural biologists in plant defence responses - Bostjan Kobe, who is an expert in on TIR domains
Collaborator Contribution We identified a novel set of effector activated genes containing TIR domains. This counter-intuitive finding led to development of a new hypothesis we have asked Prof. Kobe to collaborate on
Impact While not directly related to the work undertaken on the grant, the ability to work in an environment where Prof. Kobe was, meant I was familiar with his work and was able to meet more recently to discuss the possibilities of collaboration (March 2017). The project is multidisciplinary - we are currently in the process of developing the constructs to pursue this. This collaboration would not have happened had the PI not been at CSIRO in Brisbane on BBSRC travel monies.
Start Year 2017