miRNA-based diagnostics to improve livestock production

Lead Research Organisation: University of Edinburgh
Department Name: The Roslin Institute


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Description We performed a UK-wide survey of dairy farmers and veterinarians to reveal current practices and preferences in the diagnosis of pregnancy, mastitis and metabolic diseases in dairy farms. The survey identified a desire by farmers for a test that can diagnose pregnancy early (before 21 days after insemination) in cows, as well as end-user preferences for how such test should work
Exploitation Route The results may be used to inform the development of novel diagnostic assays to increase dairy cow reproductive efficiency and milk productivity
Sectors Agriculture, Food and Drink

Description Translating miRNA biomarker discovery into novel veterinary diagnostics to increase the efficiency of milk production
Amount £387,602 (GBP)
Funding ID BB/T004037/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 01/2020 
End 12/2021
Description Collaboraion with DestiNA Genomics to develop novel diagnostic biomarkers for livestock 
Organisation DestiNA Genomics Ltd
Country United Kingdom 
Sector Private 
PI Contribution Scientific expertise in molecular biomarkers and access to farm animal samples
Collaborator Contribution Provision of proprietary technology for direct nucleic acid detection in clinical samples
Impact BBSRC: Super FoF project - miRNA based diagnostics to improve livestock production (£473000, 2020-2022) BBSRC: FTMA -Translating MiRNA Biomarker Discovery Into Novel Veterinary Diagnostics To Increase The Efficiency Of Milk Production (£ 10039; 2020 - 2020) BBSRC: BB/S011277/1 - Pathfinder (TR) - miRNA-based diagnostics to improve livestock production (£ 12097; 2018 - 2019) BBSRC: ISCF-TFP-SA-Edinburgh - Sub-award from ISCF Transforming Food Production Seeding Award (ISCF-TFP-SA-Edinburgh). 'Roslin-DestiNA Genomics Ltd collaboration: a microRNA (miRNA) diagnostic platform for early pregnancy diagnosis in dairy cattle'. (£ 19250; 2018 - 2019) BBSRC: ISCF-TFP-SA-Edinburgh - Sub-award from ISCF Transforming Food Production Seeding Award (ISCF-TFP-SA-Edinburgh). 'Exploring the commercialisation potential or miRNA diagnostics for dairy cattle'. (£ 6200; 2018 - 2019)
Start Year 2019
Description Development of miRNA-based animal diagnostics using PCR-free technology 
Year Established 2020 
Impact None