China Partnering Award: Imperial College London - China collaboration on Actinobacillus pleuropneumoniae vaccines, diagnostics, and pathogenesis

Lead Research Organisation: Imperial College London
Department Name: Infectious Disease

Abstract

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Publications

10 25 50
 
Description This was the first visit to three groups in China who are world leading with the pig pathogen Actinobacillus pleuropneumoniae (APP) which causes lung disease in pigs. In the UK we have an active research programme with APP aimed at diagnostics and vaccines. China has over half of the world's pigs, and is the biggest market for any vaccines and diagnostics. The aim of the visit was to identify possible joint research projects, and how we might proceed in getting vaccines and diagnostics to the Chinese market. The vist was a success in that we have identified joint areas of interest with all three groups, and an offer of help to help get our current diagnostic platform to the Chinese market. The latter will depend on further internal discussions at Imperial College.
Exploitation Route Too early to say
Sectors Agriculture, Food and Drink

 
Description Huazhong Agricultural University Wuhan 
Organisation Huazhong Agricultural University
Country China 
Sector Academic/University 
PI Contribution Expertise in the the bacterial pig pathogen Actinobacillus pleuropneumoniae (APP)
Collaborator Contribution Expertise in the host response and genetics as applied to APP
Impact Only visited once so far (Nov 2020). Discussions held about possibility of PL to undertake courses next summer and/or sabbatical in the area of transcriptional regulators of APP and virulence. Also discussions about visit of one Wuhan student to Imperial regarding mutant construction. Discussions will resume once the Covid-19 epidemic has resolved.
Start Year 2020
 
Description Jilin 
Organisation Jilin University
Country China 
Sector Academic/University 
PI Contribution Expertise in the biology of the pig pathogens Actinobacillus pleuropneumoniae, Haemophilus parasuis, and Streptococcus suis. In particular, in the areas of population biology, vaccines and diagnostics.
Collaborator Contribution Expertise in the host response to the pig pathogens Actinobacillus pleuropneumoniae, Haemophilus parasuis, and Streptococcus suis.
Impact We have visited once under the award (Nov 2020) and identified areas of interest. In particular, Jilin have agreed to help us with getting a diagnostic PCR into China. We are talking to Imperial Innovations about the faesibility of doing this as proposed by Jilin.
Start Year 2020
 
Description State Key Laboratory of Veterinary Biotechnology Harbin 
Organisation Chinese Academy of Agricultural Sciences
Department Harbin Veterinary Research Institute (HVRI)
Country China 
Sector Public 
PI Contribution Expertise in the pig pathogen Actinobacillus pleuropneumoniae (APP) diagnostics, vaccines and pathogenesis.
Collaborator Contribution Complementary expertise in the pig pathogen Actinobacillus pleuropneumoniae (APP)vaccines and pathogenesis.
Impact One meeting so far (Nov 2020). Discussions were held on potential sabbatical vist for PL in the area of APP vaccines.
Start Year 2020
 
Description State School visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Schools
Results and Impact I was asked to talk to the son's class of our host in Harbin. There were 48 13 year olds. I was asked to talk about a day in the life of a 13 year old in the UK, life at University in the UK, and why we were in China. I asked a school teacher friend for advice on what to say, and also involved the Imperial International Office for slides and advice. I had learnt some rudimentary Mandarin - courtesy of my Mongolian born postdoc who was in the room - with the expectation that he would have to translate. Turned out this was not required as their English was excellent. The session was interactive involving small groups (which they were not used to) and prizes (e.g. who could name most landmarks in London etc.). The sports and school days were compared and there was question and answer sessions both ways.All students got postcards of London, winning groups got UK sweets, and the smallest boy and girl in the class London underground mugs. We found the killer stat for Chinese students to study at UK Universities - they would have their own room - instead of being in dorms of 10-12. The most enjoyable outreach session I have done in my career. I followed up with thank you and Chinese Happy New Year cards. Unqualified success for both sides. As they were in the final year at a middle school, the class will break up next year which is a shame. However, would be happy to do something similar again. Very rewarding.
Year(s) Of Engagement Activity 2019