Probing the pharmacology of the 5-HT1B receptor and its role in pulmonary disease
Lead Research Organisation:
University of Glasgow
Department Name: School of Life Sciences
Abstract
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Description | 5HT1B antagonist can reverse pulmonary hypertension |
Exploitation Route | Development of a 5HT1B antagonist for pulmonary hypertension |
Sectors | Pharmaceuticals and Medical Biotechnology |
Description | MRC project grant |
Amount | £595,086 (GBP) |
Funding ID | MR/N011112/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 04/2016 |
End | 04/2019 |
Description | 5HT1B antagonists in PAH |
Organisation | University of Cambridge |
Department | Cambridge Enterprise |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Results of BBSRC Follow on Funds |
Collaborator Contribution | Research |
Impact | n/a |
Start Year | 2010 |
Description | miR96 and pulmonary hypertension |
Organisation | United Therapeutics |
Country | United States |
Sector | Academic/University |
PI Contribution | Building on our success with the MRC CiC award and the PhD studentship we were awarded a MRC project grant to further our studies into miR96 and PAH. This created discussions with United Therapeutics who supplemented tis study. |
Collaborator Contribution | Provision of £79000 to cover costs of a patent and RNAseq |
Impact | Too early |
Start Year | 2016 |
Description | ASPET award |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | 2017 Spector award and invited lecture presented at the ASPET Annual Meeting at EB2017, April 22-26 in Chicago. |
Year(s) Of Engagement Activity | 2017 |
Description | Berlin: 4th Annual Drug Discovery and Development Symposium For Pulmonary Hypertension which will be held at the Hotel Hilton in Berlin, Germany on July 10-11, 2017. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Drug discovery presentation: serotonin and PAH |
Year(s) Of Engagement Activity | 2017 |