United States - UK Partnership: antimicrobial drug resistance in a changing agricultural world
Lead Research Organisation:
University of Liverpool
Department Name: Institute of Infection and Global Health
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Organisations
- University of Liverpool (Lead Research Organisation)
- Saint Louis Zoo (Collaboration)
- Ministry of Health (Collaboration)
- The Lancet (Collaboration)
- Veterinary Services Department (Collaboration)
- Smithsonian Institution (Collaboration)
- United States Agency for International Development (Collaboration)
- JOMO KENYATTA UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JKUAT) (Collaboration)
- Centers for Disease Control and Prevention (CDC) (Collaboration)
- The Ohio State University (Project Partner)
Publications
Falzon L
(2023)
Benefits of Using a Transdisciplinary Approach for the Design and Operationalization of a Surveillance System
in One Health Cases
Fèvre E
(2023)
Slaughter Facilities in East Africa as a Focus for One Health
in One Health Cases
Fèvre EM
(2023)
CABI Digital library
in One health cases
Hamilton KA
(2023)
Antimicrobial Resistance in Slaughterhouses, Kenya.
in Emerging infectious diseases
Hassell JM
(2020)
Africa's Nomadic Pastoralists and Their Animals Are an Invisible Frontier in Pandemic Surveillance.
in The American journal of tropical medicine and hygiene
Lawrence T
(2023)
Shifting climate zones and expanding tropical and arid climate regions across Kenya (1980-2020)
in Regional Environmental Change
Waage J
(2022)
Changing food systems and infectious disease risks in low-income and middle-income countries.
in The Lancet. Planetary health
Worsley-Tonks KEL
(2022)
Strengthening global health security by improving disease surveillance in remote rural areas of low-income and middle-income countries.
in The Lancet. Global health
Description | We have published work that started during this award focussed on AMR in the slaughterhouse environment. These are reported with the publications. In addition, the project placed us in an ideal situation to apply for more funding with US collaborators, resulting in a 5M US$ grant from the DTRA on disease emergence. |
Exploitation Route | Used by us and others to generate research ideas that led to new funding. This took a long time to happen, but a straight line can be drawn between this small award and a 5M US$ grant we obtained in collaboration with the Smithsonian Institution. |
Sectors | Agriculture Food and Drink Environment |
Description | Led in part to a national AMR strategy and to the award of a Fleming Fund Country grant, which PI Eric Fevre manages. |
First Year Of Impact | 2020 |
Sector | Agriculture, Food and Drink,Healthcare |
Impact Types | Societal Policy & public services |
Description | Kenyan National MERS Taskforce |
Geographic Reach | Africa |
Policy Influence Type | Participation in a guidance/advisory committee |
Impact | The MERS Talk Force has implemented national surveys to understand the epidemiology of MERS in the country and develop control strategies |
Description | BBSRC Agri-food technology Seeding catalyst |
Amount | £10,000 (GBP) |
Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
Sector | Public |
Country | United Kingdom |
Start | 01/2018 |
End | 12/2018 |
Description | BBSRC Translational Awards |
Amount | £80,000 (GBP) |
Funding ID | BB/R020051/1 |
Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2018 |
End | 10/2019 |
Description | CGIAR A4NH |
Amount | $20,000,000 (USD) |
Organisation | CGIAR |
Sector | Charity/Non Profit |
Country | France |
Start | 01/2014 |
End | 12/2018 |
Description | CGIAR AMR Hub |
Amount | $500,000 (USD) |
Funding ID | A4NH CGIAR AMR Hub |
Organisation | International Livestock Research Institute (ILRI) |
Sector | Charity/Non Profit |
Country | Kenya |
Start | 02/2019 |
End | 02/2022 |
Description | Fleming Fund Kenya Country Grant |
Amount | £6,000,000 (GBP) |
Funding ID | MML.574394-01681708-SUB |
Organisation | Fleming Fund |
Sector | Charity/Non Profit |
Start | 08/2019 |
End | 04/2021 |
Description | US State Department GII funding |
Amount | $8,000 (USD) |
Organisation | Ohio State University |
Sector | Academic/University |
Country | United States |
Start | 05/2016 |
End | 09/2016 |
Description | Vector-borne disease in northern Kenya (VectorINK): generating epidemiological evidence to mitigate risk |
Amount | $5,000,000 (USD) |
Funding ID | HDTRA12210018 |
Organisation | Defense Threat Reduction Agency |
Sector | Public |
Country | United States |
Start | 08/2022 |
End | 08/2028 |
Title | Biobank of samples |
Description | Approximately 4000 samples collected through the project or in part through the project are housed in the ILRI based AZIZI biobank in Kenya. These are available in an open access format to the scientific community on request. This biobank continues to grow. |
Type Of Material | Biological samples |
Year Produced | 2015 |
Provided To Others? | Yes |
Impact | Several scientific papers |
URL | http://azizi.ilri.cgiar.org/ |
Title | Sample biobank |
Description | Biobank of biological samples and associated metadata from East African field research in humans and animals |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Impact | None yet |
URL | http://azizi.ilri.cgiar.org/ |
Description | Collaboration with Smithsonian Institution |
Organisation | Smithsonian Institution |
Country | United States |
Sector | Public |
PI Contribution | PI Fevre invited as a Research Associate of the Smithsonian Conservation Biology Institute Global Health Program |
Collaborator Contribution | Joint grant applications and analysis of data |
Impact | Grant application to MRC nCOVID call, 2020 |
Start Year | 2019 |
Description | DVS |
Organisation | Veterinary Services Department |
Country | Kenya |
Sector | Learned Society |
PI Contribution | Training for fresh veterinary graduates who are attached to our programme at no cost to us for 52 weeks |
Collaborator Contribution | Partners are administering contracts for newly qualified vets who are attached to our programme |
Impact | Wide ranging contributions to project outputs more generally |
Start Year | 2018 |
Description | EPT-2 USAID/FAO |
Organisation | United States Agency for International Development |
Country | United States |
Sector | Public |
PI Contribution | We have contributed policy advice and samples to the EPT2 programme in Kenya |
Collaborator Contribution | EPT2 have contributed samples |
Impact | Analysed samples awaiting publication |
Start Year | 2016 |
Description | Kenya FELTP |
Organisation | Jomo Kenyatta University of Agriculture and Technology (JKUAT) |
Department | Kenya Field Epidemiology and Laboratory Training Program |
Country | Kenya |
Sector | Academic/University |
PI Contribution | We train FELTP residents in our programme |
Collaborator Contribution | Provide 3x full time trainees every year (total of 6 trainees at any given time) at no cost to our programme. Effectively, we are given 6 free members of full time staff. |
Impact | MSc theses x3 so far Papers x 3 in preparation 6x theses expected over the next 2 years |
Start Year | 2015 |
Description | Kenya National Antimicrobial Stewardship Committee |
Organisation | Government of Kenya |
Country | Kenya |
Sector | Public |
PI Contribution | PI Fevre is a member of the Kenya National Antimicrobial Stewardship Committee Technical Working Group on surviellance |
Collaborator Contribution | Contributions to the design of the national surveillance system for AMR |
Impact | National Action Plan for AMR |
Start Year | 2019 |
Description | Kenya VMD |
Organisation | Government of Kenya |
Country | Kenya |
Sector | Public |
PI Contribution | We have partnered with the Kenya VMD to undertake a value chain analysis of antimicrobial drugs in Kenya. We provided an intern to undertake data entry, and we provided draft questionnaires and technical input to survey design. We will jointly write a paper. |
Collaborator Contribution | Partner has provided data collected through government funded work. |
Impact | No yet |
Start Year | 2017 |
Description | Lancet One Health Commission |
Organisation | The Lancet |
Country | United Kingdom |
Sector | Private |
PI Contribution | PI Fevre is a Commissioner on the Lancet Commission on One Health |
Collaborator Contribution | Drafting of international report on Food Safety and One Health |
Impact | Not yet |
Start Year | 2019 |
Description | St Louis Zoo |
Organisation | Saint Louis Zoo |
Country | United States |
Sector | Private |
PI Contribution | Joint work in the field and joint analysis of data leading to publications |
Collaborator Contribution | Funding from their fundraising activitites |
Impact | PLoS One. 2015 Oct 16;10(10):e0140125. doi: 10.1371/journal.pone.0140125. eCollection 2015. Serological Evidence of MERS-CoV Antibodies in Dromedary Camels (Camelus dromedaries) in Laikipia County, Kenya. Deem SL1, Fèvre EM2, Kinnaird M3, Browne AS4, Muloi D5, Godeke GJ6, Koopmans M7, Reusken CB6. |
Start Year | 2013 |
Description | US Centers for Disease Control |
Organisation | Centers for Disease Control and Prevention (CDC) |
Country | United States |
Sector | Public |
PI Contribution | Testing materials created at CDC (diagnostic tests) for efficacy using stored samples |
Collaborator Contribution | Provision at no cost of lateral flow diagnostic test devices |
Impact | Preliminary data relating to testingm and an MoU/Material Transfer Agreement |
Start Year | 2018 |
Description | ZDU Kenya |
Organisation | Government of Kenya |
Department | Zoonotic Disease Unit |
Country | Kenya |
Sector | Public |
PI Contribution | ZDU is a policy partner to whom we have contributed policy advice for national level policy making |
Collaborator Contribution | Facilitation to work in Kenya |
Impact | Formal advice to policy fora. Involvment of the PI in two national task forces. |
Start Year | 2012 |
Description | News article: Kenya tackles growing threat of deadly animal viruses transmitted to humans |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Two page spread article in the Kenyan daily paper the "Business Daily" on March 2 2017 entitled 'Kenya tackles growing threat of deadly animal viruses transmitted to humans'. Article the results of a series of interviews with project staff by a science journalist |
Year(s) Of Engagement Activity | 2017 |
URL | http://www.businessdailyafrica.com/corporate/Kenya-tackles-growing-threat-of-deadly-animal-viruses-/... |
Description | PhD student participation in a US-UK-Brazil exchange |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Postgraduate students |
Results and Impact | PhD student from University of Liverpool spend 4 months between Ohio State University (USA) and Uniersity of Paraiba, Brazil, working with collaborators on lab based projects, practical training and undertaking transferable skills workshops. |
Year(s) Of Engagement Activity | 2016 |
Description | Quote and photo in Daily Nation |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Brief piece in the Kenyan Daily Nation newspaper reporting on urban health |
Year(s) Of Engagement Activity | 2017 |
Description | Uppsala Health Summit 2017 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Uppala Health Summit; The overall goal for this year's summit is to bring together a diverse group ofpolicy-makers, scientists, industry representatives and civil society to stimulate dialogue around the One Health concept as approach to emerging infectious disease threats. |
Year(s) Of Engagement Activity | 2017 |
URL | http://www.uppsalahealthsummit.se/our-summits/tackling-infectious-disease-threats-with-a-one-health-... |