France Partnering Award: Emerging Tools to Define the Role of Glycocalyces in Cell Trafficking at Endothelial Walls
Lead Research Organisation:
University of Leeds
Department Name: Sch of Biomedical Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Srimasorn S
(2022)
A quartz crystal microbalance method to quantify the size of hyaluronan and other glycosaminoglycans on surfaces.
in Scientific reports
Kirichuk O
(2023)
Competitive Specific Anchorage of Molecules onto Surfaces: Quantitative Control of Grafting Densities and Contamination by Free Anchors.
in Langmuir : the ACS journal of surfaces and colloids
Curk T
(2022)
Controlling Superselectivity of Multivalent Interactions with Cofactors and Competitors.
in Journal of the American Chemical Society
Perez S
(2023)
Glycosaminoglycans: What Remains To Be Deciphered?
in JACS Au
Jabeguero D
(2023)
Enzymatic Glyco-Modification of Synthetic Membrane Systems.
in Biomolecules
Dubacheva G
(2023)
Determinants of Superselectivity-Practical Concepts for Application in Biology and Medicine
in Accounts of Chemical Research
| Description | Superselective cell targeting through multivalent lectin-glycan interactions |
| Amount | £742,540 (GBP) |
| Funding ID | BB/X00158X/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 02/2026 |
| Description | Academic Collaboration - Bureau (LIPhy) |
| Organisation | Laboratoire Interdisciplinaire de Physique |
| Country | France |
| Sector | Public |
| PI Contribution | L. Bureau is an international project partner in BBSRC project BB/X00158X/1 'Superselective cell targeting through multivalent lectin-glycan interactions', led by R. P. Richter. |
| Collaborator Contribution | Technical expertise in blood vessels on a chip. |
| Impact | This is a multi-disciplinary collaboration, including cell and glycobiology, biomedicine, chemical biology and biophysics. |
| Start Year | 2023 |
| Description | Academic Collaboration - Dubacheva (UGA) |
| Organisation | University of Grenoble |
| Country | France |
| Sector | Academic/University |
| PI Contribution | The Richter Lab will provide access to research facilities, office and lab space during the planned visits of G. Dubacheva and her colleagues, as required for the project. |
| Collaborator Contribution | G. Dubacheva is leading the International Research Booster Project 'Stimuli-responsive polymer brushes: novel model surfaces elaboration (ResPoNSE)', of which R. Richter (Leeds) is the international partner. |
| Impact | Publication - 10.1021/jacs.2c06942 |
| Start Year | 2022 |
| Description | Academic Collaboration - Imberty (CERMAV) |
| Organisation | Centre de Recherches sur les Macromolecules Végétales |
| Country | France |
| Sector | Public |
| PI Contribution | A. Imberty is an international project partner in BBSRC project BB/X00158X/1 'Superselective cell targeting through multivalent lectin-glycan interactions', led by R. P. Richter. |
| Collaborator Contribution | Scientific expertise for the identification of lectins, and technical expertise and reagents towards the design, production and analysis of lectin modules, as required for the project. |
| Impact | This is a multi-disciplinary collaboration, including cell and glycobiology, biomedicine, chemical biology and biophysics. |
| Start Year | 2023 |