Nanometrology for Molecular Science, Medicine and Manufacture

Lead Research Organisation: University of Strathclyde
Department Name: Physics

Abstract

The lack of capacity for advancing the emerging field of nanometrology can only be addressed through stra-tegic interdisciplinary collaborations that provide a stimulating and innovative research environment to catalyse and sustain a new dimension in UK research capability. In a major strategic initiative, Strathclyde University (SU) has founded a Centre for Molecular Nanometrology (2005 - to our knowledge, the first in the world) with facilities supported by the Wolfson Foundation and the Science Research Infrastructure Fund. This Centre has the ultimate goal of recording real-time images of dynamical interactions of single molecules in-situ. With the award of a Science and In-novation Award the Centre will facilitate the high quality, innovative, multidisciplinary research environment required to nurture and develop the extra capacity needed to make the UK a leader in nanometrology. A Science and Innovation Award will also bring together the Centre and medical collaborators at King's College London (KCL), bridging the molecular measurement gap to innovation in emerging areas of strategic impor-tance such as disease pathology, diagnostic tools in nanomedicine, the design of new drug treatments and new structural materials while facilitating knowledge transfer into the healthcare and chemical industries.

Publications

10 25 50
 
Description The Science and Innovation Award (SIA) succeeded in achieving its aim of building new capacity in the strategically important area of molecular nanometrology. The SIA not only built new capacity and bridged a critical molecular measurement gap, but also helped address important problems in disease pathology, diagnostic tools in nanomedicine and the design of new structural materials, while facilitating knowledge exchange with the research, healthcare and industry sectors.

Amplification of the original SIA investment was been achieved through an additional £21.3M of competitively won funding during the course of the project. This represents over a fourfold return on the initial EPSRC/SFC investment of £4.9m. The original personnel capacity funded by the SIA totalled 25, comprising lecturers, post-doctoral fellows and research students. The additional investment provided double the original SIA capacity. Since the project began in 2006 up to the end of 2011, a total of 235 journal papers and 245 conference talks have been generated by the SIA team.

The SIA team are continuing to build on the success of the SIA through new proposals and outputs. Their future research plans will continue to incorporate synergistic and multi-centre interdisciplinary collaboration such as that achieved in the SIA, for example through the new £89m Technology Innovation Centre presently under construction at Strathclyde.
Exploitation Route The SIA research investment has led to new publications, new and expanded research directions and an enhanced skill base that continues to attract competitively won funding. Together these represent an increased research foundation for others to use, collaborate with and benefit from.
Sectors Chemicals,Education,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology

URL https://www.strath.ac.uk/staff/birchdavidprof/
 
Description For decades, a simple and convenient way of enabling people with diabetes to monitor their own blood sugar levels has eluded medical science. But now advances in nanometrology - measuring at the nanoscale - are bringing the prospect within reach with 'smart' tattoos. With support from the Research Councils UK Nanoscience Programme, researchers at the University of Strathclyde and King's College London are developing 'smart' tattoos that can be injected just under the outer layer of skin. Once in place, they function like a tiny laboratory, constantly monitoring molecular-level changes in glucose concentrations within the body. Beneficiaries: Over four million people worldwide die from diabetes or diabetes-related conditions every year. By allowing people with the disease to manage it more effectively and with less discomfort, our technique could improve their health and quality of life, while
First Year Of Impact 2012
Sector Healthcare,Pharmaceuticals and Medical Biotechnology
Impact Types Societal

 
Description MUX-TCSPC: Detection of cancer biomarkers
Amount £228,929 (GBP)
Funding ID EP/M01326x/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 10/2014 
End 09/2019
 
Description MUX-TCSPC: Detection of cancer biomarkers
Amount £27,570 (GBP)
Funding ID EP/M01326x/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 10/2014 
End 09/2019
 
Description Chaired review panel for the Physic Dep't at the National University of Ireland, Galway 
Organisation National University of Ireland
Country Ireland 
Sector Academic/University 
PI Contribution Chair : Contribution to the work of national or international committees and working groups : Chaired review panel for the Physic Dep't at the National University of Ireland, Galway
Start Year 2010
 
Description Committee Member for SPIE Photonics West/LASE 
Organisation International Society for Optics and Photonics (SPIE)
Country United States 
Sector Charity/Non Profit 
PI Contribution Member : Contribution to the work of national or international committees and working groups : Committee Member for SPIE Photonics West/LASE
Start Year 2010
 
Description External Committees: Masao Horiba Award 
Organisation Horiba
Department Masao Horiba Award (HORIBA, Ltd)
Country Japan 
Sector Public 
PI Contribution Member : Contribution to the work of national or international committees and working groups : External Committees: Masao Horiba Award
Start Year 2011
 
Description External Committees: Physical Sciences Review Panel for the National Science Foundation of the United Arab Emirates, 2009. 
Organisation National Science Foundation of the United Arab Emirates
Country United Arab Emirates 
Sector Public 
PI Contribution Member : Contribution to the work of national or international committees and working groups : External Committees: Physical Sciences Review Panel for the National Science Foundation of the United Arab Emirates, 2009.
Start Year 2009
 
Description Industry: Director Horiba Jobin Yvon IBH Ltd. 
Organisation Horiba
Department Horiba Jobin Yvon IBH Ltd
Country United Kingdom 
Sector Private 
PI Contribution Advisor : Consultancy (in kind) : Industry: Director Horiba Jobin Yvon IBH Ltd.
Start Year 2007
 
Description Joint research with King's College 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution University of Strathclyde researchers worked on this project with researchers from King's College
Start Year 2008
 
Description Member of Royal Society of Edinburgh Young Academy 
Organisation Royal Society of Edinburgh (RSE)
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Member : Membership of public/government advisory/policy group or panel
Start Year 2011
 
Description Member of Strategic Advisory Committee for EPSRC ICT programme (2008 ? 2012) 
Organisation Engineering and Physical Sciences Research Council (EPSRC)
Country United Kingdom 
Sector Public 
PI Contribution Member : Work on advisory panel to industry or government or non-gov organisation : M.D. Dawson; member Strategic Advisory Committee for EPSRC ICT programme (2008 ? 2012)
Start Year 2008
 
Description Panel member for the Academy of Finland in the area of Photonics and Modern Imaging Techniques 
Organisation Academy of Finland
Country Finland 
Sector Public 
PI Contribution Member : Contribution to the work of national or international committees and working groups : Panel member for the Academy of Finland in the area of Photonics and Modern Imaging Techniques
Start Year 2010
 
Description Renishaw Diagnostics Ltd 
Organisation Renishaw PLC
Department Renishaw Diagnostics Ltd
Country United Kingdom 
Sector Private 
PI Contribution Advisor : Consultancy (in kind) : Renishaw Diagnostics Ltd
Start Year 2008
 
Description Theme leader for SUPA Condensed Matter and Materials 
Organisation The Scottish Universities Physics Alliance (SUPA)
Country United Kingdom 
Sector Academic/University 
PI Contribution Chair : Membership of external research organisation : Theme leader for SUPA Condensed Matter and Materials
Start Year 2008
 
Description Visiting Professorship: Applied Physics, Czech Technical University, Prague. 
Organisation Czech Technical University in Prague
Country Czech Republic 
Sector Academic/University 
PI Contribution Visitor : Research and Teaching at External Organisation : Visiting Professorship: Applied Physics, Czech Technical University, Prague.
Start Year 2007
 
Description Visiting Professorship: IoP lecture tour of Ireland 
Organisation Institute of Physics (IOP)
Country United Kingdom 
Sector Learned Society 
PI Contribution Visitor : Research and Teaching at External Organisation : Visiting Professorship: IoP lecture tour of Ireland
Start Year 2011
 
Description Academy of Finland (External organisation) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Panel member for the Academy of Finland in the area of Photonics and Modern Imaging Techniques
Year(s) Of Engagement Activity 2010
 
Description Czech Technical University 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Visiting Professorship: Applied Physics, Czech Technical University, Prague.
Year(s) Of Engagement Activity Pre-2006
 
Description EPSRC (Engineering and Physical Sciences Research Council) (External organisation) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Member of Strategic Advisory Committee for EPSRC ICT programme (2008 - 2014)
Year(s) Of Engagement Activity 2008,2009,2010,2011,2012
 
Description External Committees: Physical Sciences Review Panel for the National Science Foundation of the United Arab Emirates, 2009. 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Member : Contribution to the work of national or international committees and working groups : External Committees: Physical Sciences Review Panel for the National Science Foundation of the United Arab Emirates, 2009.

Not recorded
Year(s) Of Engagement Activity 2009
 
Description Institute of Physics 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Visiting Professorship: IoP lecture tour of Ireland
Year(s) Of Engagement Activity 2011
 
Description International Society for Optics and Photonics (SPIE) (External organisation) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Committee Member for SPIE Photonics West/LASE
Year(s) Of Engagement Activity 2010
 
Description Invited seminar, Laboratory for Biomolecular Dynamics, Katolieke Universiteit Leuven, Belgium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Visitor : Invited talk : Invited seminar, Laboratory for Biomolecular Dynamics, Katolieke Universiteit Leuven, Belgium.

Not recorded
Year(s) Of Engagement Activity 2009
 
Description Masao Horiba Award (External organisation) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact External Committees: Masao Horiba Award
Year(s) Of Engagement Activity 2011
 
Description National Science Foundation of the United Arab Emirates (External organisation) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact External Committees: Physical Sciences Review Panel for the National Science Foundation of the United Arab Emirates, 2009.
Year(s) Of Engagement Activity 2009
 
Description National University of Ireland (External organisation) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Chaired review panel for the Physic Dep't at the National University of Ireland, Galway
Year(s) Of Engagement Activity 2010
 
Description New Technologies for Cancer Detection 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Contributor : Invited talk.

Not recorded
Year(s) Of Engagement Activity 2008
 
Description New Technologies for Cancer Detection 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Contributor : Invited talk.

Not recorded
Year(s) Of Engagement Activity 2008
 
Description New technologies for immunology 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Contributor : Invited talk.

Not recorded
Year(s) Of Engagement Activity 2008
 
Description New technologies for immunology 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Contributor : Invited talk.

Not recorded
Year(s) Of Engagement Activity 2008
 
Description Renishaw Diagnostics Ltd 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Renishaw Diagnostics Ltd
Year(s) Of Engagement Activity 2008,2009,2010,2011,2012
 
Description Royal Society of Edinburgh (External organisation) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Member of Royal Society of Edinburgh Young Academy
Year(s) Of Engagement Activity 2011
 
Description SUPA (External organisation) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Theme leader for SUPA Condensed Matter and Materials
Year(s) Of Engagement Activity 2008,2009,2010,2011,2012
 
Description Theme leader for SUPA Condensed Matter and Materials 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Chair : Membership of external research organisation : Theme leader for SUPA Condensed Matter and Materials.

Not recorded
Year(s) Of Engagement Activity 2008