RFI Phase 2

Lead Research Organisation: Rosalind Franklin Institute
Department Name: Research


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.


10 25 50
Description Challenge reviewer and contributor to Nurse RDI
Geographic Reach National 
Policy Influence Type Contribution to a national consultation/review
Impact The RDI review will shape government policy.
URL https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1140...
Description Structural Biology: From Molecules to Cells.
Amount £159,340 (GBP)
Funding ID 099683 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2012 
End 09/2016
Description The present invention relates to improved single domain antibodies that target SARS-CoV-2, multivalent polypeptides and fusion proteins comprising the single domain antibodies. The present invention also provides coronavirus binding molecules that bind two different epitopes on the receptor binding domain of a spike protein of a coronavirus. The coronavirus binding molecules are based on joining two antigen binding molecules together via a linker. The present invention provides the use of said single domain antibodies, multivalent polypeptides, fusion proteins and coronavirus binding molecules in treating and/or preventing coronavirus, as well as the use of said single domain antibodies, multivalent polypeptides, fusion proteins and coronavirus binding molecules in the detection and diagnosis of coronavirus using various methods, assays and kits. 
IP Reference WO2022053839 
Protection Patent / Patent application
Year Protection Granted 2022
Licensed Commercial In Confidence
Impact The patent estate is in the final stages of agreement to licence.
Title rosalindfranklininstitute/guanaco: 
Description No description provided. 
Type Of Technology Software 
Year Produced 2021 
Open Source License? Yes  
Impact Shaping tomography practice 
URL https://zenodo.org/record/5185365
Title rosalindfranklininstitute/parakeet: 
Description Phantom generator 
Type Of Technology Software 
Year Produced 2022 
Open Source License? Yes  
Impact Imported into major software packages 
URL https://zenodo.org/record/6493567
Description Media work for science media centre 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact I have supplied expert commentary on the pandemic and on science policy.
Year(s) Of Engagement Activity 2020,2021,2022,2023
URL https://www.sciencemediacentre.org/?s=naismith&cat=