500 MHz NMR Spectrometer to Support Organic, Bio-organic and Inorganic Chemistry
Lead Research Organisation:
University of Bath
Department Name: Chemistry
Abstract
NMR spectroscopy is a key tool in the elucidation of chemical structure. A new NMR spectrometer operating at higher field (500 MHz) than currently available is required by a group of synthetic chemists interested in organic, bio-organic and inorganic chemistry. This spectrometer will facilitate new research areas in the Department of Chemistry at Bath by providing access to NMR facilities with (a) high sensitivity (somewhere in the region of a 40% increase over our current 400 MHz NMR spectrometer will be provided), (b) greater resolution that will allow resonances from more complex molecules to be separated out and (c) new hardware (for example, lower frequency nuclei can be studied, while an inverse detection probe will give higher proton sensitivity, allowing compounds only available in very small amounts to be characterised and and their structures established). Specific areas that will be enabled include the synthesis of chiral molecules, modification of peptides and proteins and the development of new catalysts.
Organisations
Publications
Burling S
(2006)
Cationic Tris N-Heterocyclic Carbene Rhodium Carbonyl Complexes: Molecular Structures and Solution NMR Studies
in Organometallics
Ampt KA
(2006)
Photochemical isomerization of N-heterocyclic carbene ruthenium hydride complexes: in situ photolysis, parahydrogen, and computational studies.
in Journal of the American Chemical Society
Burling S
(2007)
C-H activation reactions of ruthenium N-heterocyclic carbene complexes: application in a catalytic tandem reaction involving C-C bond formation from alcohols.
in Journal of the American Chemical Society
Ellul CE
(2007)
Abnormally bound N-heterocyclic carbene complexes of ruthenium: C-H activation of both c4 and c5 positions in the same ligand.
in Angewandte Chemie (International ed. in English)
Chantler VL
(2008)
Stoichiometric and catalytic reactivity of the N-heterocyclic carbene ruthenium hydride complexes [Ru(NHC)(L)(CO)HCl] and [Ru(NHC)(L)(CO)H(eta2-BH4)] (L=NHC, PPh3).
in Dalton transactions (Cambridge, England : 2003)
Crittall MR
(2008)
Abnormal coordination of Arduengo's carbene upon reaction with M(3)(CO)(12) (M = Ru, Os).
in Dalton transactions (Cambridge, England : 2003)
Burling S
(2009)
The influence of N-heterocyclic carbenes (NHC) on the reactivity of [Ru(NHC)(4)H](+) with H(2), N(2), CO and O(2).
in Chemistry (Weinheim an der Bergstrasse, Germany)
Description | Range of projects covered by the instrument ranging from inorganic, organic, materials, pharmaceuticals and bilogical chemistry. |
Exploitation Route | Follow on funding as well as citations of the results by other acdemics in the literature. |
Sectors | Chemicals |
Description | Findings from research instrumentation have been used in both academic and industrial environments. Multi-user instrument so PI does not have exact details for each user. |
First Year Of Impact | 2006 |
Sector | Chemicals |
Impact Types | Societal |