Solid-state NMR Research Service for UK Universities
Lead Research Organisation:
Durham University
Department Name: Chemistry
Abstract
Solid-state NMR is an important technique for characterising and studying solid materials whether they are homogeneous or heterogeneous, crystalline or amorphous. It can be applied across a wide-range of chemistry including novel organic, inorganic, organometallic and hybrid compounds, polymers (both natural and synthetic), fuels, pharmaceutical and excipients, composites, ceramics, catalysts, liquid crystals and biologically-based systems. This proposal is for a solid-state nuclear magnetic resonance (NMR) research service. The service will be available to members of the UK academic community and will based around a new state-of-the-art 400 MHz spectrometer. It will build upon the well-established and highly-experienced service currently running at Durham. The service will offer experiment planning and interpretation, in addition to providing high-quality spectra. It will promote the application of solid-state NMR to chemical problems and will act as a centre for practical training in solid-state NMR methodology. The EPSRC service will run in parallel to a commercial service supporting the research and development needs of industry. The case for support describes how the service will be structured, how it will operate and how much instrument time will be available to its users. It is proposed that the Service will operate for a period of five years to permit a major equipment upgrade to be carried out and its impact evaluated.
Organisations
Publications
Robinson M
(2007)
A mild and efficient synthesis of ß-amino alcohols from epoxides using a mesoporous aluminosilicate catalyst
in Tetrahedron Letters
Dingwall L
(2008)
A polyoxometallate-tethered Ru complex as a catalyst in solventless phenyl acetylene oligomerisation
in Catalysis Communications
Briden C
(2007)
A study of the chemistry of isomorphous substitution and characterization of Al-ZSM-5 and Sc-ZSM-5 synthesized in fluoride media
in Inorganic Materials
Smith DA
(2008)
A truly multifunctional heterocycle: iminophosphorane, N,P chelate, and dihydropyridine.
in Angewandte Chemie (International ed. in English)
Zeng R
(2011)
Alkaline ionomer with tuneable water uptakes for electrochemical energy technologies
in Energy & Environmental Science
Watson HR
(2009)
An efficient method for 15N-labeling of chitin in fungi.
in Biomacromolecules
Kendrick E
(2009)
An investigation of the high temperature reaction between the apatiteoxide ion conductor La 9.33 Si 6 O 26 and NH3
in J. Mater. Chem.
Bird M
(2010)
Assessment of oxygen plasma ashing as a pre-treatment for radiocarbon dating
in Quaternary Geochronology
Bontemps S
(2009)
Bridging M-Cl bonds with ambiphilic phosphine-borane ligands.
in Chemistry, an Asian journal
Attfield M
(2008)
Characterisation and properties of the n=3 and n=4 members of the Al2[O3PCnH2nPO3](H2O)2F2 framework aluminium alkylenediphosphonate series
in Solid State Sciences
Sbircea L
(2008)
Chemoenzymatic synthesis of chiral 4,4'-bipyridyls and their metal-organic frameworks.
in Chemical communications (Cambridge, England)
Castro M
(2007)
Co-templating and modelling in the rational synthesis of zeolitic solids.
in Chemical communications (Cambridge, England)
Egerton T
(2007)
Comparison of photooxidation and photoreduction reactions on TiO2 nanoparticles
in Journal of Photochemistry and Photobiology A: Chemistry
Griesser U
(2008)
Conformational Polymorphism in Oxybuprocaine Hydrochloride
in Crystal Growth & Design
Alam N
(2008)
Crystalline mesoporous silicates from layered precursors
in Journal of Materials Chemistry
Jones M
(2010)
Cu(II) homogeneous and heterogeneous catalysts for the asymmetric Henry reaction
in Journal of Molecular Catalysis A: Chemical
Fujii K
(2010)
Direct structure elucidation by powder X-ray diffraction of a metal-organic framework material prepared by solvent-free grinding.
in Chemical communications (Cambridge, England)
Orera A
(2008)
Effect of oxygen content on the 29Si NMR, Raman spectra and oxide ion conductivity of the apatite series, La8+xSr2-x(SiO4)6O2+x/2.
in Dalton transactions (Cambridge, England : 2003)
Hashem M
(2011)
Enhancing the rigidity of a network polymer of intrinsic microporosity by the combined use of phthalocyanine and triptycene components,
in Polymer Chemistry
Marr AC
(2011)
Entrapping homogeneous catalysts by sol-gel methods: the bottom-up synthesis of catalysts that recycle and cascade.
in Dalton transactions (Cambridge, England : 2003)
Robinson MW
(2009)
Epoxide ring-opening and Meinwald rearrangement reactions of epoxides catalyzed by mesoporous aluminosilicates.
in Organic & biomolecular chemistry
Smith DA
(2010)
Exploiting non-innocent ligands to prepare masked palladium(0) complexes.
in Angewandte Chemie (International ed. in English)
Description | The Solid-State NMR service provided NMR spectra and interpretation services for users without ready access to this important, but relatively expensive, analytical technique for analysing solid materials. This work fed into a large number of papers (74 listed here) over the period. Aided by the baseline EPSRC funding, the Service ran a busy commercial operation over the funding period, supplying services to 10-15 companies per year in, for example, the petrochemical, pharmaceutical, agrichemical, polymer and defence industries. |
Exploitation Route | This is best addressed by individual users of the Service. We have indicated below the areas in which the Service had a significant impact. |
Sectors | Agriculture, Food and Drink,Chemicals,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
Description | EPSRC |
Amount | £668,649 (GBP) |
Funding ID | Contract 01SSN01112011 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 11/2011 |
End | 10/2016 |