Warwick Centre for Analytical Science
Lead Research Organisation:
University of Warwick
Department Name: Chemistry
Abstract
Analytical Science involves the development and application of new methods to measure the composition and structure of manufactured and natural substances of all types. The analytical sector in the UK underpins many vital industries (e.g. food, chemical, pharmaceutical, environmental, materials), is crucial to process and cost control, to product quality and competitiveness, to industrial compliance with environmental and safety legislation, and to the delivery of healthcare and justice. Crucially, progress in Analytical Science is also essential to advances in many key research areas including materials and life sciences. Modern analytical problems often require high spatial resolution in three dimensions, resulting in very large, complex data sets. Moreover, there is a need to combine information from multiple data sets of very different provenance. Recent official reviews have warned that, despite its central importance to the UK's economic and scientific competitiveness, Analytical Science in the UK suffers from low esteem and fragmentation, and lacks interdisciplinarity. The result is a shortage of analytical scientists, and an alarmingly low level of innovation compared to other countries. Research and innovation-led reinvigoration of this area is essential for the UK's economic and social well-being. The University of Warwick invests heavily in multidisciplinary research and education, and has a strong research base in Analytical Science in the Departments of Chemistry, Physics, Statistics, Engineering, Biological Sciences and the Medical School. Building on this philosophy, we have responded to the fourth Science and Innovation Call by proposing lectureships in three new interdisciplinary research areas (Chemometrics and Experimental Design, Chemical and Structural Characterisation of Materials, and Mass Spectrometry) that will be combined with diverse research in Analytical Science at Warwick to found a new Centre for Analytical Science, expected to boost the profile of Analytical Science in the UK and world-wide. Recognising the fact that scientific progress crucially depends on communication and collaboration between different disciplines and sectors, a central aim of the Centre will be to bring together people from academia and industry with the objective of providing a platform for identification, definition, and implementation of new Analytical Science research goals including the development of new instrumentation, and new methods for data acquisition and statistical inference. The process of innovation requires a dialogue between academia and the private sector. As stated in the Lambert report, the best forms of knowledge transfer involve human interaction . Therefore, the Centre will have an academic/industrial Advisory Board, and will develop, through its new Analytical Forum, a visitor and outreach programme, not only to enable the exchange of ideas, knowledge, and technology between developers and users of analytical tools in public and private sectors, but also to foster new collaborations.Applicants of the very highest quality will be attracted by offering excellent research facilities supported by PhD students and post-doctoral researchers in a well resourced multinational, multidisciplinary environment. The Centre will develop training programmes in Analytical Science, statistics and transferable skills. The integration of research and education in the Centre will offer a comprehensive approach to Analytical Science, helping to provide the UK with the skills base essential to remain internationally competitive.Warwick will nurture the new Centre by guaranteeing long-term support for the area, and by investing heavily in state-of-the-art equipment, purpose-built accommodation and infrastructure. There will be development of modules for CPD, PG and UG training which will help sustainability.
Publications
Wills RH
(2014)
Structural characterization of actinomycin D using multiple ion isolation and electron induced dissociation.
in Journal of the American Society for Mass Spectrometry
Lam YPY
(2020)
Determination of the Aggregate Binding Site of Amyloid Protofibrils Using Electron Capture Dissociation Tandem Mass Spectrometry.
in Journal of the American Society for Mass Spectrometry
Wei J
(2015)
The Competitive influence of Li+, Na+, K+, Ag+, and H+ on the fragmentation of a PEGylated polymeric excipient.
in Journal of the American Society for Mass Spectrometry
Faulques E
(2016)
Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems
in Journal of Visualized Experiments
Smith DC
(2016)
Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems.
in Journal of visualized experiments : JoVE
Gondim A
(2019)
Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity
in MedChemComm
Kumar SA
(2021)
Dose- and time-dependent tolerability and efficacy of organo-osmium complex FY26 and its tissue pharmacokinetics in hepatocarcinoma-bearing mice.
in Metallomics : integrated biometal science
Ballesta A
(2019)
Kinetic analysis of the accumulation of a half-sandwich organo-osmium pro-drug in cancer cells.
in Metallomics : integrated biometal science
Wilson N
(2013)
Weak mismatch epitaxy and structural Feedback in graphene growth on copper foil
in Nano Research
Bichoutskaia E
(2012)
High-precision imaging of an encapsulated Lindqvist ion and correlation of its structure and symmetry with quantum chemical calculations
in Nanoscale
Banerjee S
(2024)
Experimental and theoretical evidence for unprecedented strong interactions of gold atoms with boron on boron/sulfur-doped carbon surfaces
in Nanoscale Advances
Huang H
(2019)
Targeted photoredox catalysis in cancer cells.
in Nature chemistry
Sun L
(2014)
Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation.
in Nature communications
Barry NP
(2014)
Fabrication of crystals from single metal atoms.
in Nature communications
Soldevila-Barreda JJ
(2015)
Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design.
in Nature communications
Kashtiban RJ
(2014)
Atomically resolved imaging of highly ordered alternating fluorinated graphene.
in Nature communications
Páez C
(2012)
Robust signatures in the current-voltage characteristics of DNA molecules oriented between two graphene nanoribbon electrodes
in New Journal of Physics
Wilson N
(2010)
On the structure and topography of free-standing chemically modified graphene
in New Journal of Physics
Chen F
(2018)
Transfer Hydrogenation and Antiproliferative Activity of Tethered Half-Sandwich Organoruthenium Catalysts.
in Organometallics
Gatti A
(2018)
Half-Sandwich Arene Ruthenium(II) and Osmium(II) Thiosemicarbazone Complexes: Solution Behavior and Antiproliferative Activity.
in Organometallics
Millett A
(2015)
Contrasting Anticancer Activity of Half-Sandwich Iridium(III) Complexes Bearing Functionally Diverse 2-Phenylpyridine Ligands
in Organometallics
Farley SJ
(2022)
Photoactive Platinum(II) Azopyridine Complexes.
in Photochemistry and photobiology
Marsden A
(2013)
Is graphene on copper doped?
in physica status solidi (RRL) - Rapid Research Letters
Banerjee S
(2019)
Dual-action platinum(II) Schiff base complexes: Photocytotoxicity and cellular imaging
in Polyhedron
Romero-Canelón I
(2015)
Systems approach to metal-based pharmacology.
in Proceedings of the National Academy of Sciences of the United States of America
Li H
(2012)
Protein flexibility is key to cisplatin crosslinking in calmodulin.
in Protein science : a publication of the Protein Society
Barry N
(2014)
100 years of metal coordination chemistry: from Alfred Werner to anticancer metallodrugs
in Pure and Applied Chemistry
Lopes L
(2020)
THE FUNDAMENTAL IMPORTANCE OF BASIC SCIENCE: EXAMPLES OF HIGH-IMPACT DISCOVERIES FROM AN INTERNATIONAL CHEMISTRY NETWORK
in Química Nova
Lopez-Clavijo A
(2013)
Tandem mass spectrometry for the study of glyoxal-derived advanced glycation end-products (AGEs) in peptides
in Rapid Communications in Mass Spectrometry
Qi Y
(2012)
Absorption-mode spectra on the dynamically harmonized Fourier transform ion cyclotron resonance cell.
in Rapid communications in mass spectrometry : RCM
Wei J
(2015)
Extensive fragmentation of pheophytin-a by infrared multiphoton dissociation tandem mass spectrometry.
in Rapid communications in mass spectrometry : RCM
Qi Y
(2013)
Mapping the protein-binding sites for novel iridium(III) anticancer complexes using electron capture dissociation.
in Rapid communications in mass spectrometry : RCM
Spencer J
(2016)
Coherence lifetime broadened optical transitions in a 2 atom diameter HgTe nanowire: a temperature dependent resonance Raman study
in RSC Advances
Carter R
(2016)
Radiosensitisation of human colorectal cancer cells by ruthenium(II) arene anticancer complexes
in Scientific Reports
Pandey P
(2013)
Pd-doped reduced graphene oxide sensing films for H2 detection
in Sensors and Actuators B: Chemical
Pandey PA
(2011)
Physical vapor deposition of metal nanoparticles on chemically modified graphene: observations on metal-graphene interactions.
in Small (Weinheim an der Bergstrasse, Germany)
Dyson M
(2013)
A new approach to high resolution, high contrast electron microscopy of macromolecular block copolymer assemblies
in Soft Matter
Minas G
(2012)
A hybrid procedure for detecting global treatment effects in multivariate clinical trials: theory and applications to fMRI studies.
in Statistics in medicine
Wootton CA
(2019)
Structural analysis of peptides modified with organo-iridium complexes, opportunities from multi-mode fragmentation.
in The Analyst
Armstrong J
(2023)
Correction to "Vibrational Motions Make Significant Contributions to Sequential Methyl C-H Activations in an Organometallic Complex".
in The journal of physical chemistry letters
Armstrong J
(2021)
Vibrational Motions Make Significant Contributions to Sequential Methyl C-H Activations in an Organometallic Complex.
in The journal of physical chemistry letters
Lin TY
(2011)
A gain and bandwidth enhanced transimpedance preamplifier for Fourier-transform ion cyclotron resonance mass spectrometry.
in The Review of scientific instruments
Lin TY
(2012)
A low noise single-transistor transimpedance preamplifier for Fourier-transform mass spectrometry using a T feedback network.
in The Review of scientific instruments
Shi H
(2022)
Biomedical Applications of Inorganic Photochemistry
Pizarro A
(2013)
Comprehensive Inorganic Chemistry II