Microchemical single droplet reaction analysis by online cavity ring-down spectroscopy
Lead Research Organisation:
University of Oxford
Department Name: Oxford Chemistry
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
Claire Vallance (Principal Investigator) |
Publications
Vallance C
(2016)
Open-access microcavities for chemical sensing.
in Nanotechnology
Trichet AA
(2016)
Nanoparticle Trapping and Characterization Using Open Microcavities.
in Nano letters
Trichet AA
(2014)
Open-access optical microcavities for lab-on-a-chip refractive index sensing.
in Lab on a chip
Rushworth CM
(2011)
Fabrication of an optical fiber reflective notch coupler.
in Optics letters
Rushworth CM
(2011)
Top notch design for fiber-loop cavity ring-down spectroscopy.
in Analytical chemistry
Rushworth C
(2013)
Sensitive analysis of trace water analytes using colourimetric cavity ringdown spectroscopy
in Anal. Methods
Rushworth C
(2012)
Cavity-enhanced optical methods for online microfluidic analysis
in Chemical Physics Letters
Neil SR
(2011)
Broadband cavity-enhanced absorption spectroscopy for real time, in situ spectral analysis of microfluidic droplets.
in Lab on a chip
James D
(2012)
High-sensitivity online detection for microfluidics via cavity ringdown spectroscopy
in RSC Advances
Coles D
(2015)
Diffusion-driven continuous-wave-pumped organic dye lasers
in Laser & Photonics Reviews
Description | The original award was concerned with combining cavity ringdown spectroscopy with a sample contained within a microfluidic chip. Near the end of the grant period I began to collaborate with the group of Jason Smith in Oxford's Department of Materials, on combining optical microcavities with chemical sensing in microfluidic environments. This work grew directly out of work funded by the EPSRC, though was not part of the original grant. We have shown that we can achieve extremely sensitive measurements of refractive index and optical absorption (absorption spectroscopy) for liquid samples, and also that optical microcavities can be used to carry out detailed characterisation of nanoparticles trapped in the cavity. |
Exploitation Route | While the methods used in the original EPSRC-funded research proved to be quite difficult to use, the microcavity methods that have followed show considerable promise for a variety of applications. We are planning to form a spin-out company based on this technology over the next few months, in order to develop commercial instruments. |
Sectors | Chemicals Education Energy Environment Healthcare Pharmaceuticals and Medical Biotechnology |
Description | Leverhulme Trust Project Grant |
Amount | £229,389 (GBP) |
Organisation | The Leverhulme Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2012 |
End | 03/2015 |
Description | Paul Instrument Fund |
Amount | £72,635 (GBP) |
Organisation | The Royal Society |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2012 |
End | 10/2014 |