Hybrid approaches to tissue engineering
Lead Research Organisation:
Imperial College London
Department Name: Materials
Abstract
Our life expectancy is increasing and we are outliving our skeletal tissues. There is a need for orthopaedic surgery to move from replacement of tissues to regeneration. To do this medical devices are required that can stimulate the body's own healing mechanisms. Over the last 10-15 years, tissue engineering has promised that combining engineering principles with cells will lead to regeneration of tissues, however skin is the only tissue engineered product used clinically. The reasons skeletal tissue engineering has not been successful is that materials have not been developed that fulfill all the engineering design criteria for regenerative device (scaffold) and how materials interact with cells is not fully understood. A new hybrid approach is proposed where hybrid refers to an integrated interdisciplinary approach and the innovation in materials engineering that is needed. New materials must be developed that mimic the mechanical properties and structure of natural tissues. The aim is to build an interdisciplinary research team that can deliver high impact step changes in the way tissue engineering research is carried out to make skeletal tissue engineering a clinical reality. Team members will have expertise in materials chemistry and processing, multi-scale characterisation, materials modelling, cell biology, orthopaedic surgery and technology transfer. The adventurous programme will benefit the UK by improving the quality of life of patients, increasing the efficiency of orthopaedic surgery, reducing surgical costs and boosting the UK economy by ensuring patients recover and return to work more rapidly.The core platform technology will be novel nanostructured (hybrid) materials that can be designed to stimulate bone growth or cartilage regeneration before they are remodelled in the body and replaced by natural healthy tissue. To make these complex materials a clinical reality they must be understood from the atomic through the nano to the macro level and optimised with respect to cellular response. Computer models and improved characterisation methods are needed. Bone scaffolds must stimulate stem cells to produce bone and new ways of growing cells in devices may be necessary in order for blood vessels to grow throughout bone scaffolds and for cartilage regeneration to become a reality. If new devices are to reach the clinic, technology transfer must be considered. My vision is to build and lead a world renowned research group successful in musculoskeletal tissue engineering with a new field of inorganic/ organic hybrid materials engineering at its core. The research group will attract best, internationally leading researchers to the UK (or to stay in the UK). It will involve international and UK collaborators, with the UK at the focus, placing it at the forefront of biomaterials and tissue engineering. There will be focus on developing a dynamic and supportive research environment and on developing the career of group members so they will become the next leaders of the new fields that will evolve from the group's work.
Planned Impact
There are several target groups that will benefit directly from this research. Orthopaedic, neurological and plastic surgeons, patients and health services (e.g. the NHS) will benefit as end users. Patients and UK economy will benefit as patients recover more rapidly and to a fuller extend, allowing them to return to work more rapidly. Medical device companies will benefit from potentially market leading products and new tools for their quality assurance. Currently, the NHS performs 60 000 hip (600 000 worldwide) and 70 000 knee replacements (>1M wordwide) annually due to degenerating cartilage. Unfortunately the implants eventually fail (usually after 15-25 years) and revision operations are common, causing patients intense pain and lack of mobility. Revision operations cost the NHS 2-3 times that of the initial operation. This research programme has the potential to create devices that can regenerate diseased cartilage so that the number of joint replacements and therefore revision operations are drastically reduced. 25 000 bone graft operations are carried out in the UK annually (>1M worldwide). Current best practice for surgeons is to take bone from the pelvis and move it to the defect (autograft). Problems are that the supply of bone is limited and there is donor site morbidity. After the operation, the pelvis is extremely painful, recovery time is long (4 weeks to 6 months) and 46% of people have complications that require further treatment, many needing revision operations. Autograft procedures also require two clinicians in theatre. There is therefore a clinical need for synthetic grafts that regenerate bone defects to healthy natural bone. Orthopaedic surgeons require a new device that is a porous construct that stimulates bone growth but is tough and has some flexibility. Surgeons also want to be able to cut the device to shape during the operation and be press-fit into bone defects.These devices will reduce recovery time by stimulating the regenerative process, thereby improving healing rate and removing the need to harvest the bone before implantation, reducing operation time, which will save the NHS 100M per year alone. A reduction in associated secondary disease treatment is particularly pertinent in the context of the UK's aging population, who will benefit from improved the quality of life, reducing the burden on a heavily overloaded social care system. The devices for bone regeneration have the potential to fill 10-15% of the $500M global market. If successful cartilage regeneration to be achieved, the market would be significantly higher. Companies must invest in the materials and take them through regulatory approval. The intellectual property generated will be filed by Imperial Innovations and licensed by the collaborating companies, e.g. RepRegen Ltd., (London), contributing to the growth of the UK's strategically important biosciences industry. They will also form partnerships with larger medical device companies (e.g. NovaBone and Stryker), increasing the adoption rate of the new materials. To ensure that the materials are designed to meet the end user's needs, I have collaborations with leading surgeons within the Imperial College Medical School with whom I meet regularly to discuss their needs and latest results. Progress will be communicated to other surgeons via presentation sessions and through high impact publications. Progress will be communicated to the general public by building on my current media contacts, having recently given interviews to BBC Radio and the Daily Mail. The Victoria and Albert Museum will benefit as they have included a scaffold in their new permanent exhibition of ceramics. Outreach activities, in conjunction with Lord Robert Winston's Outreach Laboratory, will encourage more high quality students to join the fields of materials science and engineering and tissue engineering and aim to increase the number of female scientists.
Organisations
- Imperial College London (Lead Research Organisation)
- University of Milano-Bicocca (Collaboration)
- UNIVERSITY OF READING (Collaboration)
- Nagoya Institute of Technology (Collaboration, Project Partner)
- Evonik Industries (Collaboration)
- Stryker (United States) (Project Partner)
- University of Central Florida (Project Partner)
- Stryker Osteosynthesis (Switzerland) (Project Partner)
- Imperial College Healthcare NHS Trust (Project Partner)
- University of Warwick (Project Partner)
- NovaBone Products LLC (Project Partner)
- Saarland University (Project Partner)
- RepRegen Ltd (Project Partner)
People |
ORCID iD |
Julian Jones (Principal Investigator) |
Publications
Mohammed AA
(2020)
Auto-catalytic redox polymerisation using nanoceria and glucose oxidase for double network hydrogels.
in Journal of materials chemistry. B
Mohammed AA
(2023)
Nanocomposite Hydrogels with Polymer Grafted Silica Nanoparticles, Using Glucose Oxidase.
in Gels (Basel, Switzerland)
Nakamura J
(2013)
Tracking the formation of vaterite particles containing aminopropyl-functionalized silsesquioxane and their structure for bone regenerative medicine
in Journal of Materials Chemistry B
Nelson M
(2021)
3D printed silica-gelatin hybrid scaffolds of specific channel sizes promote collagen Type II, Sox9 and Aggrecan production from chondrocytes
in Materials Science and Engineering: C
Nommeots-Nomm A
(2017)
Highly degradable porous melt-derived bioactive glass foam scaffolds for bone regeneration.
in Acta biomaterialia
Obata A
(2012)
Sintering and Crystallization of Phosphate Glasses by CO 2 -Laser Irradiation on Hydroxyapatite Ceramics
in International Journal of Applied Ceramic Technology
Obata A
(2012)
Induction of hydroxycarbonate apatite formation on polyethylene or alumina substrates by spherical vaterite particles deposition.
in Materials science & engineering. C, Materials for biological applications
Obata A
(2011)
Hydroxyapatite Coatings Incorporating Silicon Ion Releasing System on Titanium Prepared Using Water Glass and Vaterite
in Journal of the American Ceramic Society
Obata A
(2013)
Cotton wool-like poly(lactic acid)/vaterite composite scaffolds releasing soluble silica for bone tissue engineering.
in Journal of materials science. Materials in medicine
Poologasundarampillai G
(2014)
Cotton-wool-like bioactive glasses for bone regeneration.
in Acta biomaterialia
Description | Silica/PCL hybrids have unique mechanical properties: the "glass" can bounce and be hit with a hammer. They also have self-healing properties. When cartilage cells are grown on 3D printed silica/PCL hybrid of defined pore size, type II collagen is produced that is indicative of articular cartilage. Hybrid scaffolds can be produced by 3D printing directly from the sol. A new 3D printing technique was developed. Using co-cultures of cells inside silica/ gelatin hybrid foam scaffolds, vascular networks were grown inside scaffolds. Monodispersed bioactive glass nano particles, with control of particle size, can be synthesised from a modified Stober process, but it is challenging to introduce cations into the nano particles at high concentrations. When the particles are introduced to stem cells, they were internalised but did not trigger differentiation or toxicity. When macrophage cells are seeded on bioactive glass sol-gel scaffolds, they differentiate into osteoclasts and remodel the scaffolds. In vivo performance of sol-gel scaffolds is very dependent on calcium ion incorporation and subsequent release. Cotton-wool like bioactive glass scaffolds can be produced by electrospinning calcium containing sol-gel compositions. New hybrid biomaterials can be produced with tailored mechanical properties and biodegradation rate by introducing natural polymers in the sol-gel process but only if coupling agents (organosilanes) are used to bond the organic to the inorganic components. The reactions of GPTMS are very dependent on pH of the reaction and are more difficult to control than previously thought. Calcium can be incorporated into the silicate sol-gel network at room temperature through the use of calcium alkoxides. |
Exploitation Route | TheraGlass Ltd is assisting with commercialisation of the cotton-wool bioactive glass scaffolds, potentially for wound healing applications. |
Sectors | Education Healthcare Manufacturing including Industrial Biotechology |
Description | We developed a new transparent 3D printable hybrid material with unprecedented mechanical properties, including intrinsic self-healing, which was also 3D printable. Corning replicated the work in a 2021 publication J Mater Chem B 2021 Jun 3;9(21):4400-4410. doi: 10.1039/d1tb00555c A Healthcare Impact Partnership Grant was successfully obtained from EPSRC to begin translation of the hybrid technology in 2016. The technology was included in an NIHR Global Health Research Group on POsT Conflict Trauma in Sri Lanka (£2.2 m); PrOTeCT, National Institute for Health (1613745), awarded 2017 A US patent WO2017168168 was granted in 2021 Evonik became project partners in 2021 and expressed interest in synthesising the raw materials as part of the translation process In 2022, Imperial College Enterprise office invested £65 k in the technology to accelerate translation |
First Year Of Impact | 2016 |
Sector | Healthcare,Manufacturing, including Industrial Biotechology |
Impact Types | Economic |
Description | 3D printing multifunctional devices without internal interfaces for cartilage repair |
Amount | £615,329 (GBP) |
Funding ID | EP/W034093/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 01/2023 |
End | 12/2025 |
Description | Biodegradable hybrid screws for ligament-bone interface regeneration |
Amount | £1,119,981 (GBP) |
Funding ID | EP/S025782/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 11/2019 |
End | 05/2023 |
Description | EPSRC Doctoral Award for Louise Connell |
Amount | £47,000 (GBP) |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 11/2013 |
End | 11/2014 |
Description | EPSRC Responsive Mode |
Amount | £136,177 (GBP) |
Funding ID | EP/M004414/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2014 |
End | 10/2016 |
Description | EPSRC Responsive Mode |
Amount | £615,722 (GBP) |
Funding ID | EP/M019950/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2015 |
End | 03/2018 |
Description | Healthcare Impact Partnership |
Amount | £1,072,444 (GBP) |
Funding ID | EP/N025059/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2016 |
End | 06/2019 |
Description | Imperial College Enterprise DT-Prime |
Amount | £65,000 (GBP) |
Organisation | Imperial College London |
Sector | Academic/University |
Country | United Kingdom |
Start | 01/2022 |
End | 07/2022 |
Description | Marie Curie Individual Fellowship |
Amount | € 200,000 (EUR) |
Organisation | European Commission |
Sector | Public |
Country | European Union (EU) |
Start | 05/2016 |
End | 05/2018 |
Description | NIHR Global Health Research Global Health Research Group on POsT Conflict Trauma; PrOTeCT |
Amount | £1,880,000 (GBP) |
Funding ID | 1613745 |
Organisation | National Institute for Health Research |
Sector | Public |
Country | United Kingdom |
Start | 11/2017 |
End | 10/2020 |
Description | Nanocomposites for bone regeneration |
Organisation | Nagoya Institute of Technology |
Country | Japan |
Sector | Academic/University |
PI Contribution | Julian Jones was appointed Visiting Professor, giving an annual seminar at Nagoya Institute of Technology. Post doctoral researcher Gowsihan Poologasaundarampillai employed at Nagoya Institute of Technology for 18 months, PhD student Sen Lin appointed as a post doctoral researcher at Nagoya Institute of Technology for 12 months. Hosted Dr Akiko Obata (Assistant Professor) for 1 year , Jin Nakamura (PhD student) for 1 year and Sungho Lee (PhD Student) for 3 months. Maria Nelson and Lizzie Norris (PhD students) visited Nagoya for 3 Months each. Anthony Macon employed from Jones' group as an Assistant Professor. Hosted 4 Masters students from NiTech. Associate Professors Akiko Obata and Toshihisa Mizuno joined Jones' group for 2 months and 1 year respectively. |
Collaborator Contribution | Exchange Programme funded through JSPS Sent 9 researchers to Julian Jones' research group Employed a post doctoral researcher and a phd student from Julian Jones' research group Employed and Assistant Professor from Julian Jones' group |
Impact | Maçon, A. L. B., Lee, S., Poologasundarampillai, G., Kasuga, T., Jones, J. R. "Synthesis and dissolution behaviour of CaO/SrO-containing sol-gel-derived 58S glasses" Journal of Materials Science, 2017, DOI: 10.1007/s10853-017-0869-0.Wang, J., Zhou, P., Obata, A., Jones, J. R., Kasuga, T. "Preparation of cotton-wool-like poly(lactic acid)-based composites consisting of core-shell-type fibers", Materials. 2015: 8: 7979-7987, DOI :10.3390/ma8115434 Gao, C. X., Ito, S., Obata, A., Mizuno, T., Jones, J. R., Kasuga, T. "Fabrication and in vitro characterization of electrospun poly (gamma-glutamic acid)-silica hybrid scaffolds for bone regeneration" Polymer, 2016: 91:106-117. DOI: 10.1016/j.polymer.2016.03.056. Wang, J., Zhou, P., Obata, A., Jones, J. R., Kasuga, T. "Preparation of cotton-wool-like poly(lactic acid)-based composites consisting of core-shell-type fibers", Materials. 2015: 8: 7979-7987, DOI :10.3390/ma8115434. Poologasundarampillai, G., Wang, D., Li, S., Nakamura, J., Bradley, R., Lee, P. D., Stevens, M. M., McPhail, D. S., Kasuga, T., Jones, J. R., "Cotton-wool-like bioactive glasses for bone regeneration", Acta Biomaterialia, 2014: 10: 3733-3746. Obata, A., Ito, S., Iwanag, N., Mizuno, T., Jones, J. R., Kasuga, T. "Poly(?-glutamic acid)-silica hybrids with fibrous structure: effect of cation and silica concentration on molecular structure, degradation rate and tensile properties" RSC Advances, 2014: DOI: 10.1039/c4ra08777a. Wang, D., Poologasundarampillai, G., van den Bergh, W., Chater, R., Kasuga, T., Jones, J. R., McPhail, D. S. "Strategies for the chemical analysis of highly porous bone scaffolds using secondary ion mass spectrometry (SIMS)" Biomedical Materials, 2014: 9 (1): 015013. Nakamura, J., Poologasundarampillai, G., Jones, J. R., Kasuga, T. "Tracking the formation of vaterite particles containing aminopropyl-functionalized silsesquioxane and their structure for bone regenerative medicine" Journal of Materials Chemistry B, 2013: 1: 35: 4446-4454. Obata, A. Ozasa, H., Kasuga, T., Jones, J. R. "Cotton wool-like poly(lactic acid)/vaterite composite scaffolds releasing soluble silica for bone tissue engineering" Journal of Materials Science: Materials in Medicine, 2013: 24: 1649-1658. Fujikura, K., Obata, A., Lin, S., Jones, J. R., Law, R. V., Kasuga, T. "Preparation of electrospun poly(lactic acid)-based hybrids containing siloxane-doped vaterite particles for bone regeneration" Journal of Biomaterials Science, Polymer Edition 2012: 23:10, 1369-1380 Obata, A. Hasegawa, D., Nakamura, J., Jones, J. R., Kasuga, T. "Induction of hydroxycarbonate apatite formation on polyethylene or alumina substrates by spherical vaterite particles deposition", Materials Science and Engineering C, 2012: 32: 1976 - 1981. Obata, A., Jones, J. R., Akiyoshi, S., Kasuga, T. "Sintering and crystallization of phosphate glasses by CO2-Laser irradiation on hydroxyapatite ceramics" International Journal of Applied Ceramic Technology, 2012: 9: 541-549. Obata, A., Hashimoto, T., Kasuga, T., Jones, J. R. "Hydroxyapatite coatings incorporating silicon ion releasing system on titanium prepared by using water glass and vaterite" Journal of American Ceramics Society, 2011: 94 (7): 2074-2079. Wakita, T. Obata, A., Poologasundarampillai, G., Jones, J. R., Kasuga, T., "Preparation of siloxane-containing poly(lactic acid)-vaterite hybrid membranes for guided bone regeneration" Composites Science and Technology, 2010: 70: 1889-1893. |
Start Year | 2009 |
Description | Reactions of organosilanes in the sol-gel process |
Organisation | University of Milano-Bicocca |
Country | Italy |
Sector | Academic/University |
PI Contribution | PhD students Louise Connell, Oliver Mahony and Francesca Tallia visited Bicocca to understand the reactivity of the organosilane GPTMS Hosted PhD student Laura Russo |
Collaborator Contribution | Laura Russo developed a new hybrid based on Silica and PEG Hosted Louise Connell and Oliver Mahony and investigated the reaction of GPTMS with water and nucleophiles Tall developed a new hybrid with self-healing properties |
Impact | EPSRC Healthcare Impact Partnership Grant "Additive manufacturing of advanced medical devices for cartilage regeneration: minimally invasive early intervention" Connell, L. S., Gabrielli, L., Mahony, O., Russo, L., Cipolla, L., Jones, J. R. "Functionalizing natural polymers with alkoxysilane coupling agents: reacting 3-glycidoxypropyl trimethoxysilane with poly(?-glutamic acid) and gelatin" Polymer Chemistry, 2017: 8: 1095-1103, DOI: 10.1039/c6py01425a. Gabrielli, L., Connell, L. S., Russo, L., Jiménez-Barbero, J., Nicotra, F., Cipolla, L., Jones, J. R. Exploring GPTMS reactivity against simple nucleophiles: chemistry beyond hybrid materials fabrication, RSC Advances, 2014: 4: 1841 - 1848. Russo, L., Gabrielli, L., Valliant, E. M., Nicotra, F., Jiménez-Barbero, J., Cipolla, L., Jones, J. R. "Novel silica/bis(3-aminopropyl) polyethylene glycol inorganic/organic hybrids by sol-gel chemistry" Materials Chemistry and Physics, 2013:140: 168-175. Gabrielli, L., Russo, L. Poveda, A., Jones, J. R., Nicotra, F., Jiménez-Barbero, J., Cipolla, L. "Epoxide opening versus silica condensation during sol-gel hybrid biomaterial synthesis", Chemistry, a European Journal, 2013: 19: 7856-7864. |
Start Year | 2010 |
Description | Supramolecular polymers for 3D printing |
Organisation | University of Reading |
Department | School of Chemistry, Food and Pharmacy |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Cellular response studies to new polymers for ink development |
Collaborator Contribution | Development of new supramolecular polymers |
Impact | Hart, L., Li, S., Sturgess, C., Wildman, R., Jones, J. R., Hayes, W. "3D printing of biocompatible supramolecular polymers and their composites" ACS Applied Materials & Interfaces DOI: 10.1021/acsami.5b10471. |
Start Year | 2014 |
Description | Synthesis of bouncy bioglass inks for 3D printing medical devices |
Organisation | Evonik Industries |
Country | Germany |
Sector | Private |
PI Contribution | We have developed a biomaterial with unique mechanical and biomedical properties for cartilage regeneration. Evonik supply raw materials to medical device companies |
Collaborator Contribution | Evonik are working on the industrial synthesis process |
Impact | Investment of £65k from Imperial College Enterprise DT Prime to advance translation |
Start Year | 2021 |
Title | BIOACTIVE NANOCOMPOSITE MATERIAL |
Description | The present invention relates to a porous inorganic/organic hybrid nanoscale composite comprising an enzymatically biodegradable organic polymer and a sol-gel derived silica network, its production and use as a macroporous scaffold in tissue engineering. |
IP Reference | WO2009030919 |
Protection | Patent application published |
Year Protection Granted | 2009 |
Licensed | Yes |
Impact | A TSB grant was obtained by Repregen to accelerate translation. |
Title | HYBRID MATERIALS AND PROCESS FOR PRODUCTION THEREOF |
Description | The invention relates to inorganic-organic hydrid materials comprising interpenetrated organic and inorganic components, wherein the organic component comprises polymer chains formed at least in part by ring-opening polymerization of a cyclic monomer, and processes for the production thereof. |
IP Reference | WO2017168168 |
Protection | Patent / Patent application |
Year Protection Granted | 2017 |
Licensed | No |
Impact | Healthcare Impact Partnership grant from the EPSRC and partnership with surgeons and industry to begin technology transfer Granted in USA and EU Pending in EU Further funding from : 2017: NIHR Global Health Research Group on POsT Conflict Trauma in Sri Lanka; PrOTeCT, National Institute for Health (1613745) £2.4 M 2022: Imperial College DT Prime "A medical device for cartilage regeneration", £65k 2022: UKRI IAA grant "Translation of Bouncy Bioglass towards Spinout" £94k over 1 year |
Description | Discovery Channel |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Took part in a Discovery Channel film showcasing bioactive glass and regenerative medicine |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.discoveryuk.com/future-now/ |
Description | Inaugural Lecture broadcast |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Inaugural Public Lecture professionally recorded and edited and put on Youtube |
Year(s) Of Engagement Activity | 2016 |
URL | https://www.youtube.com/watch?v=71RA0VhTC04 |
Description | Interview with IScience |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Undergraduate students |
Results and Impact | Interview with Imperial college IScience Student Media team which was then on YouTube |
Year(s) Of Engagement Activity | 2015 |
URL | http://www.isciencemag.co.uk/features/iscientist-julian-jones-interview/ |
Description | Pint of Science Festival |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | Yes |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | The audience fully engaged with my presentation, spreading the understanding that glass is an advanced high tech material Group members also got outreach experience Members of the public were enthused about Materials Science, when most did not realise it is a discipline |
Year(s) Of Engagement Activity | 2014 |
URL | http://pintofscience.co.uk/events/london/spoton/ |
Description | Pint of Science science festival talk |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Pint of Science science festival talk |
Year(s) Of Engagement Activity | 2018 |
URL | https://pintofscience.co.uk/event/fixing-our-body |
Description | UN International Year of Glass 2022 pitch/launch video broadcast |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Video broadcast created to pitch to the UN to make 2022 the International Year of Glass. The video included footage at Imperial College on bioglasss and bouncy bioglass. The proposal was successful. The initial pitch was viewed by the UN council and 13k views online (YouTube) The video was also used to launch the International Year of Glass activities and received a further 2k views. |
Year(s) Of Engagement Activity | 2020,2021 |
URL | https://www.youtube.com/watch?v=A6ZEaWvlz6k |
Description | YouTube Channel |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Industry/Business |
Results and Impact | YouTube Channel set up and populated to promote bioactive glass research |
Year(s) Of Engagement Activity | 2015 |
URL | https://www.youtube.com/channel/UCNKc2if3dCNM1a1ynoFEh1A |