An New Frontier in Design: The Simulation of Open Engineered Biological Systems
Lead Research Organisation:
Newcastle University
Department Name: Sch of Engineering
Abstract
Biology will lie at the heart of many 21st century technologies to sustainably address the numerous challenges facing societies such as waste, energy, water, healthcare, new chemicals and materials, and agriculture. This ambitious project seeks to develop a suite of universal principles and models for the scalable simulation of open biological systems thereby allowing the engineering of new functionalities offered by natural or synthetic, mainly micro-, organisms for the benefit of mankind.
We live in a world that is increasingly urbanising and populated putting many pressures on the globe and its natural resources. One of the biggest challenges is sustaining global health, prosperity and well-being in a way that does not harm societies requiring these benefits nor the earth's natural resources. In the last two centuries, engineering has been central in providing the infrastructure and resources responsible for these societal gains. The engineering challenge in the 21st century is to continue to make these, and new, provisions for more people in a more sustainable way.
Thomas Tredgold, the first President of the Institute of Civil Engineers, defined engineering as "the art of directing the great sources of Power in Nature for the use and benefit of mankind". Engineering has expanded as it has sought and exploited new sources of Power in Nature and new concepts and tools by which said sources can be manipulated. Many believe that Biology is the next source of Power and that Engineering Biology it will be central to our goal of generating a new suite of intrinsically sustainable technologies. However, there is a substantial gap between rhetoric and reality in many accounts of the application of engineering biology. We will only open up this frontier if we are a brutally honest about the limitations, astute in our analysis of the bottlenecks and effective in innovations to obviate them. Though this is a contemporary challenge, it is something engineers have always done, using mathematical models and scientific principles to winnow the pipe dreams from the awesome but achievable (Rankine, 1855).
One of the greatest limitations in biology is taking what is possible in the test-tube and making it a reality in the reactor or environment; using relatively cheap resources and in the face of a large and highly diverse natural microbial population. In this project, we seek to use the best scientific principles and theories to develop a suite of universal principles and models for the scalable simulation of open biological systems. These models will allow the engineering design of new functionalities offered by natural or synthetic organisms for the benefit of mankind for a range of technologies addressing a range of different challenges.
We live in a world that is increasingly urbanising and populated putting many pressures on the globe and its natural resources. One of the biggest challenges is sustaining global health, prosperity and well-being in a way that does not harm societies requiring these benefits nor the earth's natural resources. In the last two centuries, engineering has been central in providing the infrastructure and resources responsible for these societal gains. The engineering challenge in the 21st century is to continue to make these, and new, provisions for more people in a more sustainable way.
Thomas Tredgold, the first President of the Institute of Civil Engineers, defined engineering as "the art of directing the great sources of Power in Nature for the use and benefit of mankind". Engineering has expanded as it has sought and exploited new sources of Power in Nature and new concepts and tools by which said sources can be manipulated. Many believe that Biology is the next source of Power and that Engineering Biology it will be central to our goal of generating a new suite of intrinsically sustainable technologies. However, there is a substantial gap between rhetoric and reality in many accounts of the application of engineering biology. We will only open up this frontier if we are a brutally honest about the limitations, astute in our analysis of the bottlenecks and effective in innovations to obviate them. Though this is a contemporary challenge, it is something engineers have always done, using mathematical models and scientific principles to winnow the pipe dreams from the awesome but achievable (Rankine, 1855).
One of the greatest limitations in biology is taking what is possible in the test-tube and making it a reality in the reactor or environment; using relatively cheap resources and in the face of a large and highly diverse natural microbial population. In this project, we seek to use the best scientific principles and theories to develop a suite of universal principles and models for the scalable simulation of open biological systems. These models will allow the engineering design of new functionalities offered by natural or synthetic organisms for the benefit of mankind for a range of technologies addressing a range of different challenges.
Planned Impact
The potential impact of this research is as broad and ubiquitous as microbial communities themselves. We hope to transform our ability to predict and engineering naturally occurring microbial communities where ever they are found. The water industry is hopefully but a launching pad for our approach. But here transformative biological technologies could change the treatment of wastes in temperate climate from a net energy consumer to a net energy generator. We might, at the same time, find ways to rationally engineer low energy attached growth systems to remove micropollutants. This will benefit the industry and their customers by lowering costs and insulating consumers from the effect of higher energy costs. At a totally different scale, in a totally different industry, we could design personal care products in simulated hair follicles, reducing the cost and time of getting an idea to market and widening the range of biota friendly products. In the oil industry corrosion is thought to cost between 10 and 100 billion dollars a year: valid multiscale model of may allow us to ameliorate or avoid this cost by conceiving of corrosion resistant pipe surface geometries or by using ecological principles to discourage the bacteria responsible for corrosion. The impact of paints used in the shipping industry to reduce drag could be tested in silico before ever being applied to a ship. The wealth of microbial resource in the natural world could be harnessed more predictably and more quickly with benefits that we have not yet conceived. This would allow engineers to use microbes in areas where, for cultural or technical reasons, synthetic biology may not be an option. And where synthetic biology does have a role to play in an open microbial system, the "synbio" solutions will be found faster and more cheaply. If these ideas are even half right, we could enter a generation of engineering biology with broad applications opening up new lines of business for start-ups and established enterprises alike.
Organisations
- Newcastle University (Lead Research Organisation)
- Oak Ridge National Laboratory (Collaboration)
- University of Minho (Collaboration)
- Unilever (Netherlands) (Collaboration)
- Zhejiang University (Collaboration)
- UNIVERSITY OF NEWCASTLE (Collaboration)
- Norwegian University of Science and Technology (NTNU) (Collaboration)
- Aix-Marseille University (Collaboration)
- University of Applied Sciences Lübeck, Germany (Collaboration)
- AkzoNobel (Collaboration)
- Northumbrian Water (Collaboration)
- Northumbrian Water Group plc (Project Partner)
Publications
Ammar Y
(2015)
Influence of surface roughness on the initial formation of biofilm
in Surface and Coatings Technology
Bashiri R
(2022)
Looking for lipases and lipolytic organisms in low-temperature anaerobic reactors treating domestic wastewater.
in Water research
Bashiri R
(2022)
The limitations of the current protein classification tools in identifying lipolytic features in putative bacterial lipase sequences.
in Journal of biotechnology
Beal J
(2019)
Communicating Structure and Function in Synthetic Biology Diagrams.
in ACS synthetic biology
Brown MR
(2019)
Coupled virus - bacteria interactions and ecosystem function in an engineered microbial system.
in Water research
Cao Y
(2019)
Hierarchical Rose Petal Surfaces Delay the Early-Stage Bacterial Biofilm Growth.
in Langmuir : the ACS journal of surfaces and colloids
Cao Y
(2020)
Antiwetting and Antifouling Performances of Different Lubricant-Infused Slippery Surfaces.
in Langmuir : the ACS journal of surfaces and colloids
Cao Y
(2018)
Nanostructured titanium surfaces exhibit recalcitrance towards Staphylococcus epidermidis biofilm formation.
in Scientific reports
Cao Y
(2016)
Modelling the nanomechanical response of a micro particle-matrix system for nanoindentation tests.
in Nanotechnology
Description | This award, we we seek to use the best scientific principles and theories to develop a suite of universal principles and models for the scalable simulation of open biological systems. These models will allow the engineering design of new functionalities offered by natural or synthetic organisms for the benefit of mankind for a range of technologies addressing a range of different challenges. The award has brought together researchers with expertise in a range of disciplines, from biology to m |
Exploitation Route | We have strong collaboration with our partners, Northumbrian Water and Mott MacDonald. These organisations are actively participating in our research and, when the project is more mature, will work with us to put the findings into practice. |
Sectors | Agriculture Food and Drink Chemicals Energy Environment Healthcare Manufacturing including Industrial Biotechology Pharmaceuticals and Medical Biotechnology Security and Diplomacy |
URL | http://research.ncl.ac.uk/nufeb/ |
Description | The tools and concepts we have developed are being explored with industrial partners using the EPSRC Impact Acceleration Awards. The outcomes of NUFEB continue to be made in Industry and Academia. We are currently working with Veolia to model the media in moving bed bioreactors (MBBR) to help to refine the engineering of annamox bacteria. In addition the BEWISE pilot scale facility is being used to make strategically important baseline measures of nitrous oxide emissions from trickling filter plants in a 400K industry funded project. Our large scale biofilm facility BIOGRIMES has being used by Akzo-Nobel to improve anti-fouling coatings for the shipping industry. |
First Year Of Impact | 2014 |
Sector | Agriculture, Food and Drink,Chemicals,Digital/Communication/Information Technologies (including Software),Energy,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology,Security and Diplomacy |
Impact Types | Economic Policy & public services |
Description | AI Summer Institute Project |
Amount | £12,000 (GBP) |
Organisation | Oak Ridge National Laboratory |
Sector | Public |
Country | United States |
Start | 05/2019 |
End | 08/2019 |
Description | CASE Studentship |
Amount | £76,000 (GBP) |
Organisation | Unilever |
Sector | Private |
Country | United Kingdom |
Start | 08/2018 |
End | 09/2022 |
Description | EBI Metagenomics - enabling the reconstruction of microbial populations |
Amount | £81,402 (GBP) |
Funding ID | BB/R015031/1 |
Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
Sector | Public |
Country | United Kingdom |
Start | 07/2018 |
End | 08/2021 |
Description | EBI Metagenomics Portal - Towards a better understanding of community metabolism |
Amount | £251,060 (GBP) |
Funding ID | BB/M011453/1 |
Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2015 |
End | 05/2018 |
Description | EPSRC Equipment Business Case |
Amount | £1,196,635 (GBP) |
Funding ID | EP/P001564/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 05/2016 |
End | 06/2019 |
Description | EPSRC Strategic Equipment Award |
Amount | £487,050 (GBP) |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 01/2018 |
End | 01/2020 |
Description | Engineering Microbial-Induced Carbonate Precipitation via Meso-Scale Simulations |
Amount | £604,550 (GBP) |
Funding ID | EP/S013997/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 08/2019 |
End | 08/2023 |
Description | Experimental Biology and Engineering at the Pilot Scale - Strategic Equipment |
Amount | £1,196,634 (GBP) |
Funding ID | EP/P001564/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2016 |
End | 12/2021 |
Description | Individual Based Modeling of Chemically Mediated Microbial Interactions in Biofilms |
Amount | $207,000 (USD) |
Organisation | National Science Foundation (NSF) |
Sector | Public |
Country | United States |
Start | 01/2021 |
End | 12/2023 |
Description | Interdisciplinary Prize |
Amount | £250,000 (GBP) |
Funding ID | A1175 |
Organisation | Rosetrees Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2017 |
End | 06/2020 |
Description | NUFEB fellowship |
Amount | £2,000 (GBP) |
Organisation | Newcastle University |
Department | School of Civil Engineering and Geosciences |
Sector | Academic/University |
Country | United Kingdom |
Start | 11/2016 |
End | 10/2018 |
Title | BEWISE |
Description | A unique pilot plant facility for wastewater treatment. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2021 |
Provided To Others? | Yes |
Impact | Just commissioned |
URL | https://www.ncl.ac.uk/be-wise/ |
Title | Conjugative CRISPR-Cas9 vector based system |
Description | A single vector CRISPR-Cas9 system for genome engineering of bacterial species, delivered by conjugative transfer between mixed donor and recipient species |
Type Of Material | Model of mechanisms or symptoms - non-mammalian in vivo |
Provided To Others? | No |
Impact | Still in development. In testing phase now. |
Title | 2D microbial growth model |
Description | A comprehensive individual based model (2D) that describes the microbial growth as a function of the energy available in the surroundings. It includes a detailed sub model of the physico chemistry of the system: gas-liquid and acid base equilibriums are considered with the aim of understanding how environmental changes affect the growth of the different microorganisms in a population. |
Type Of Material | Computer model/algorithm |
Provided To Others? | No |
Impact | This individual based model is the first one able to describe comprehensively the physico chemistry of the system and how it affects the microbial growth. The growth parameters are estimated using the information of the surroundings and it employs only first principles like thermodynamic calculations, instead of relying on measurements at the population level. |
Title | Individual-based modeling of microbial communities |
Description | The model is used to simulate bacteria communities in biofilms. |
Type Of Material | Computer model/algorithm |
Year Produced | 2016 |
Provided To Others? | Yes |
Impact | This model can be used to address some scientific problems related to biofilms. |
URL | https://github.com/nufeb/NUFEB |
Title | NUFEB github repository |
Description | For warehousing relevant data and computer codes. |
Type Of Material | Computer model/algorithm |
Year Produced | 2016 |
Provided To Others? | Yes |
Impact | Academic impact, improved understanding and warehousing of data and computer codes |
Title | NUFEB model |
Description | Individual-based model of microbial communities |
Type Of Material | Computer model/algorithm |
Year Produced | 2017 |
Provided To Others? | Yes |
Impact | NUFEB team internally shortlisted for bidding for an EPSRC CDT |
URL | https://github.com/nufeb/NUFEB |
Description | Akzo-Nobel (Still Active) |
Organisation | AkzoNobel |
Department | AkzoNobel UK |
Country | United Kingdom |
Sector | Private |
PI Contribution | We are using our unique biofilm experimental facility to develop new protocols for product development with the help of funding from the National Biofilm Innovation Centre |
Collaborator Contribution | They are helping build a bespoke test facility for them |
Impact | A novel test rig for biofilm testing |
Start Year | 2019 |
Description | Biosensor for estrogen detection |
Organisation | Norwegian University of Science and Technology (NTNU) |
Country | Norway |
Sector | Academic/University |
PI Contribution | Plasmid cloning and experimental assays for estrogen detection |
Collaborator Contribution | Provision of plasmid, reporter inserts and general experimental protocol |
Impact | Sharing of experimental protocol |
Start Year | 2016 |
Description | Cécilia GEFFROY internship student from Polytech, MARSEILLE, France |
Organisation | Aix-Marseille University |
Country | France |
Sector | Academic/University |
PI Contribution | Time devoted to student internship |
Collaborator Contribution | Sponsored and hosted by Erasmus |
Impact | Enhancement of student skills |
Start Year | 2014 |
Description | Collaboration with University of Minho in Portugal |
Organisation | University of Minho |
Country | Portugal |
Sector | Academic/University |
PI Contribution | The University of Minho read our work and invited me to speak at a conference in Braga. Following that meeting we initiated a collaboration. We are currently hosting Joao Costa from the University of Minho to do research with us. |
Collaborator Contribution | They initiated the partnership and have paid for the two way exchange |
Impact | One paper in preparation so far |
Start Year | 2022 |
Description | Felix Maximilian Stoll internship student from University of Applied Sciences Lübeck, Germany |
Organisation | University of Applied Sciences Lübeck, Germany |
Country | Germany |
Sector | Academic/University |
PI Contribution | Time devoted from staff to the collaboration. |
Collaborator Contribution | Sponsored and hosted by Erasmus |
Impact | Student skills development |
Start Year | 2016 |
Description | Full and pilot-scale wastewater treatment facilities |
Organisation | Northumbrian Water |
Country | United Kingdom |
Sector | Private |
PI Contribution | Design of pilot plants and inserts for full-scale trickling filter wastewater treatment plants and liaison with NWL |
Collaborator Contribution | Time, materials and an opportunity of access to and insertion of rigs into a real full-scale plant that would not normally be possible |
Impact | Infrastructure facilities for monitoring microbial communities |
Start Year | 2014 |
Description | Northumbrian Water |
Organisation | Northumbrian Water |
Country | United Kingdom |
Sector | Private |
PI Contribution | We work with Northumbria water on biofilm from trickle filter. |
Collaborator Contribution | The in-kind support from Northumbrai Water is to provide us free access to harvest biofilms in their trickle filters. |
Impact | Access to facilities |
Start Year | 2016 |
Description | ORNL |
Organisation | Oak Ridge National Laboratory |
Country | United States |
Sector | Public |
PI Contribution | Working to develop a parallel implementation of the NUFEB codebase which can be deployed on the computer system at ORNL (Titan). Development of experimental designs to be tested on the equipment at ORNL. |
Collaborator Contribution | Access to computer time on their supercomputer (Titan) along with technical support for using this system. Access to fabrication labs for constructing nano-scale experiment equipment. The conducting of experiments |
Impact | There are currently no outputs from this collaboration. A number are planned but have yet to be achieved. This is a multi-disciplinary collaboration including: Computing, Biology, Civil Engineering, and Engineering. |
Start Year | 2017 |
Description | Oak Ridge |
Organisation | Oak Ridge National Laboratory |
Country | United States |
Sector | Public |
PI Contribution | Providing the current NUFEB software, Providing knowledge and experience of biological processes This has been interactions to exchange ideas and provide access to the skills and code developed through NUFEB |
Collaborator Contribution | Access to world-leading supercomputers, access to support for how to use said computers, access to bespoke experimental equipment. $250,000 in-kind contributions |
Impact | Summer AI internship |
Start Year | 2016 |
Description | Sam Charlton internship student from Newcastle University |
Organisation | University of Newcastle |
Country | Australia |
Sector | Academic/University |
PI Contribution | Time devoted towards internship support |
Collaborator Contribution | Enhanced collaboration with the host organisation. |
Impact | Enhancement of skills developed by student during placement. |
Start Year | 2015 |
Description | Unilever |
Organisation | Unilever |
Country | United Kingdom |
Sector | Private |
PI Contribution | We are making physical and computer models of oral biofilms |
Collaborator Contribution | They have brought resources, intellect and industrial know how |
Impact | Too early to say. This is a very multidisciplinary collaboration. |
Start Year | 2019 |
Description | Wenbo Wang internship student from Zhejiang University, China |
Organisation | Zhejiang University |
Country | China |
Sector | Academic/University |
PI Contribution | Time devoted towards supervision of student internship. |
Collaborator Contribution | Enhanced collaboration with the host organisation. Sponsored by Lin Guangzhao & Hu Guozan Graduate Education International Exchange Fund |
Impact | Enhancement of student skills during placement. |
Start Year | 2015 |
Title | BioPSy |
Description | Parameter synthesis tool for SBML models. |
Type Of Technology | Software |
Year Produced | 2015 |
Open Source License? | Yes |
Impact | Development of biological tools. Biopsy is a tool that performs parameter set synthesis on biological models specified using the Systems Biology Markup Language (SBML) and corresponding time series data. |
URL | https://github.com/dreal/biology |
Title | NUFEB1.0 |
Description | An individual based model of bacteria was implemented on open source platform LAMMPS. |
Type Of Technology | Software |
Year Produced | 2006 |
Open Source License? | Yes |
Impact | The software can be used to address some scientific problems related to bacterial communities. |
URL | https://github.com/nufeb/NUFEB |
Description | 14th IWA Leading Edge Conference on Water and Wastewater Technologies LET2017 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | The IWA Leading Edge Conference on Water and Wastewater Technologies is designed to be the place where new ideas are introduced and the opportunity is provided to interact with the "best of the best". This is the global conference where new insights into how pioneering science, technological innovation and leading practices shape the major transformation in water management that is underway |
Year(s) Of Engagement Activity | 2017 |
Description | 3rd IWA Specialized International Conference Ecotechnologies for Wastewater Treatment 2016 (ecoSTP16) Cambridge |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Keynote: Measurement and Theory in Wastewater Treatment |
Year(s) Of Engagement Activity | 2016 |
URL | http://www.ecostp2016.com/ |
Description | 43rd International Conference On Metallurgical Coatings & Thin Films (ICMCTF), April, 2017, San Diego, USA |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Dr. Chen was the Session chair and session organizer for Biointerface Biointerface Description : This session is to study the bacterial adhesion, cell mechanics, biofilm mechanics, cell-materials interactions. |
Year(s) Of Engagement Activity | 2017 |
Description | American Society for Microbiology Conference 2016 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Invited: Improving the Design of Biological Wastewater Treatment Systems through Theoretical Ecology |
Year(s) Of Engagement Activity | 2016 |
URL | https://www.asmmicrobeglobal.com/Home.aspx |
Description | American Society for Microbiology, Washington DC 2016 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation: Towards multiscale modelling of microbial communities |
Year(s) Of Engagement Activity | 2016 |
URL | http://conferences.asm.org/index.php/2012-02-09-21-04-52/past-conferences/2-uncategorised/400-confer... |
Description | CIWEM Wastewater Treatment Intensification Conference |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | CIWEM Technical Seminar, Reader in Environmental Engineering, Invited Speaker (Russell Davenport) |
Year(s) Of Engagement Activity | 2018 |
Description | EuroBiofilm conference, Amsterdam, Sept. 2017 |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | This is a typical conference for biofilm modelling, biofilm mechanics and biological aspects of biofilms. |
Year(s) Of Engagement Activity | 2017 |
Description | Formal Methods for the Synthesis of Biomolecular Circuits |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Formal Methods for the Synthesis of Biomolecular Circuits were presented and discussed. |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.dagstuhl.de/en/program/calendar/semhp/?semnr=18082 |
Description | Frontiers International Conference on Wastewater Treatment FICWT |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | The Frontiers International Conference on Wastewater Treatment 2017, aimed to create a forum for promoting the discussion amongst scientists, professionals and academia in different areas of the broader theme of environmental engineering and sciences. |
Year(s) Of Engagement Activity | 2017 |
URL | http://ficwtm.unipa.it/ |
Description | ISME Conference 2016 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Keynote: The Numbers Game |
Year(s) Of Engagement Activity | 2016 |
URL | http://www.isme-microbes.org/isme16 |
Description | IWA Leading Edge Technology Workshop |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | A workshop (held by invitation) at the International Water Association's Leading Edge Technology Workshop |
Year(s) Of Engagement Activity | 2019 |
Description | Industry Focussed Workshop |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | A workshop aimed at practitioners |
Year(s) Of Engagement Activity | 2019 |
Description | International Conference on Environmental Protection and Simulation, 2016 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Keynote: Progress and Problems in the Design of Wastewater Treatment systems |
Year(s) Of Engagement Activity | 2016 |
Description | MRM2: From synthetic ecology to natural ecosystems |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | The second international symposium on "Microbial resource management (MRM)" focuses on the transition "from synthetic ecology to natural ecosystems". In the past few years many exiting new technologies have led to an increased understanding of microbial community composition. Now, especially with the rise of synthetic ecology approaches, microbial ecologists try to breach the gap between in vitro assemblies and natural ecosystems |
Year(s) Of Engagement Activity | 2017 |
URL | http://www.mrm.ugent.be/mrm2 |
Description | Materials Research Society Annual meeting, Boston, Dec 2017 |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | This is one of the largest conferences on materials research. |
Year(s) Of Engagement Activity | 2017 |
Description | Materials Research Society of Singapore conference, June 2017, |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | This is one of the largest conferences on materials research. |
Year(s) Of Engagement Activity | 2017 |
Description | Molecular Microbial Ecology Group conference 2016 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Postgraduate students |
Results and Impact | Research conference with presentation given by MS to post-doctoral researchers and post-graduate students |
Year(s) Of Engagement Activity | 2016 |
Description | Multiscale Biology Summer School,Date: 11 - 14 September 2017, University of Nottingham |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | Summer School Workshop |
Year(s) Of Engagement Activity | 2017 |
Description | New Horizons in Atomistic Simulation; N8 HPC, CCP5 & UKCP Network Event |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | The annual N8 HPC / CCP5 / UKCP Atomistic Simulation Network event is an annual event to discuss new trends and directions in atomistic simulations. |
Year(s) Of Engagement Activity | 2018 |
URL | https://n8hpc.org.uk/new-horizons-in-atomistic-simulation-n8-hpc-ccp5-ukcp-network-event/ |
Description | Oral Presentation "Virus abundance dynamics and their biotic and abiotic interactions in a full scale activated sludge plant", 16th International Symposium on Microbial Ecology (ISME), Montreal, 2016. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Attended and presented research at both the International symposium on microbial ecology and microbial ecology in wastewater engineering conferences. Purpose - disseminate research to an international audience. Impacts - NA. Outcomes - NA. |
Year(s) Of Engagement Activity | 2016 |
Description | Oral Presentation "Virus abundance dynamics and their biotic and abiotic interactions in a full scale activated sludge plant", 6th IWA International Conference on Microbial Ecology and Water Engineering (MEWE), Copenhagen, 2016. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Attended and presented research at both the International symposium on microbial ecology and microbial ecology in wastewater engineering conferences. Purpose - disseminate research to an international audience. Impacts - NA. Outcomes - NA. |
Year(s) Of Engagement Activity | 2016 |
Description | Presentation to Non Point Source Pollution Meeting in Wuhan China |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | A presentation to a large international meeting in China |
Year(s) Of Engagement Activity | 2019 |
Description | Seeing is Believing - Imaging the Processes of Life, EMBL Heidelberg, Germany, 4 - 7 Oct 2017, |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Event exploring the Imaging of the processes of life |
Year(s) Of Engagement Activity | 2017 |
Description | Seminar presentation - April 2017: Montana State University, USA. |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2017 |
Description | Seminar presentation - Dec 2016: Beihang University , China |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2016 |
Description | Seminar presentation - Dec 2016: Perking University (Beida), China |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2017 |
Description | Seminar presentation - Dec 2016: Tsinghua University, China |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2016 |
Description | Seminar presentation - Dec.2017: Jinan University, China |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2017 |
Description | Seminar presentation - Dec.2017: South China University of Technology, China |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2017 |
Description | Seminar presentation - Jan 2017: Chongqing University , China |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2017 |
Description | Seminar presentation - July 2016: Nanyang Technological University, Singapore |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2016 |
Description | Seminar presentation - July 2016: University of Malaya, Malaysia |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2016 |
Description | Seminar presentation - Nov 2016: National Physical Lab, UK |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2016 |
Description | Seminar presentation- July 2016: National University of Singapore |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2016 |
Description | Seminar presentations - Dec.2017: South China Normal University, China |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2017 |
Description | Seminar presentations - Dec.2017: Xi'an Jiao Tong University, China |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Seminar presentation |
Year(s) Of Engagement Activity | 2017 |
Description | Sensitivity Analysis of Model Outputs (SAMO) Conference |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Conference on Sensitivity Analysis of Model Outputs (SAMO) |
Year(s) Of Engagement Activity | 2016 |
Description | The 12th OpenFOAM Workshop |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | The annual OpenFOAM® Workshop is the premier international forum for researchers, industrial users, code developers, consultants and academics to come together and present their work, discuss the code, network, and learn about new developments in OpenFOAM®. It is a community event, welcoming all users from novice to experienced, and users of all branches of the code. |
Year(s) Of Engagement Activity | 2017 |
URL | http://openfoam-extend.sourceforge.net/OpenFOAM_Workshops/OFW12_2017_Exeter/index.html |
Description | The 4th Stevens Conference on Bacteria-Material Interactions, June 2017 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | This is a typical conference for bacteria-materials interactions. |
Year(s) Of Engagement Activity | 2017 |
Description | The 6th Thesinge biofilm meeting, Netherland, Sept. 2016, |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | This is a typical conference for bacteria-materials interactions, biofilm mechanics and biological aspects of biofilms. |
Year(s) Of Engagement Activity | 2016 |
Description | UK-Brazil Workshop on Wastewater treatment 2016 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Keynote: : Measurement and Theory in Wastewater Treatment |
Year(s) Of Engagement Activity | 2016 |
Description | Unilever Colworth 2016 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Industry/Business |
Results and Impact | Invited Presentation: Modelling and Simulation in Microbial Ecology |
Year(s) Of Engagement Activity | 2016 |
Description | Workshops and conferences |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Researchers from the same area as mine presented their works and discussed. |
Year(s) Of Engagement Activity | 2016 |