Core capability for Chemistry Research
Lead Research Organisation:
Imperial College London
Department Name: Chemistry
Abstract
The National Importance of a vibrant and successful university Chemistry research sector cannot be underestimated. The RSC's report on the Economic Benefits of Chemistry showed that the UK's upstream chemicals industry and downstream chemistry-using sectors contributed a combined total of £258 billion in added-value in 2007, equivalent to 21% of UK GDP, and supported over 6 million UK jobs. This output is underpinned by some of the world's most successful University Chemistry research, reflecting the fruits of many years of investment. On-going fundamental research is essential, not only to maintain a continuing flow of scientific and technological breakthroughs, but also to ensure that the UK maintains a highly skilled and innovative workforce; it is through these trained people that the UK will adopt and advance new ideas, successfully exploit new technologies, and develop new and better products and services. The ability to develop and exploit chemically-derived technology will fuel economic activity, and is a necessary condition for attracting inward investment to the UK. The RSC report also showed that the quality of UK chemists and the reputation for excellence of the UK's university chemical science base significantly influences companies in decisions to locate within the UK, or to retain a UK-based research presence.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Planned Impact
Please see Pathways to Impact
Organisations
Publications
Celaya-Sanfiz A
(2015)
Self-condensation of acetone over Mg-Al layered double hydroxide supported on multi-walled carbon nanotube catalysts
in Journal of Molecular Catalysis A: Chemical
Cecchini M
(2014)
Heavy Metal Sensing Using Self-Assembled Nanoparticles at a Liquid-Liquid Interface
in Advanced Optical Materials
Casey D
(2014)
Amphiphilic drug interactions with model cellular membranes are influenced by lipid chain-melting temperature
in Journal of The Royal Society Interface
Casey A
(2015)
Cyano substituted benzothiadiazole: a novel acceptor inducing n-type behaviour in conjugated polymers
in Journal of Materials Chemistry C
Casey A
(2015)
Novel soluble thieno[3,2-b]thiophene fused porphyrazine
in RSC Advances
Carroll L
(2015)
Mn-salen catalysed benzylic C-H activation for the synthesis of aryl [(18)F]CF3-containing PET probes.
in Chemical communications (Cambridge, England)
Carreras P
(2015)
A microfluidic platform for size-dependent generation of droplet interface bilayer networks on rails.
in Biomicrofluidics
Carreras P
(2014)
Microfluidic generation of droplet interface bilayer networks incorporating real-time size sorting in linear and non-linear configurations.
in Biomicrofluidics
Carmona D
(2014)
Chiral transition-metal complexes as Brønsted-acid catalysts for the asymmetric Friedel-Crafts hydroxyalkylation of indoles.
in Dalton transactions (Cambridge, England : 2003)
Cappel UB
(2016)
Evidence for photo-induced charge separation between dye molecules adsorbed to aluminium oxide surfaces.
in Scientific reports
Cao Y
(2015)
Solution Processed Bismuth Sulfide Nanowire Array Core/Silver Sulfide Shell Solar Cells
in Chemistry of Materials
Campbell J
(2014)
Fabrication of hybrid polymer/metal organic framework membranes: mixed matrix membranes versus in situ growth
in J. Mater. Chem. A
Campbell J
(2015)
Improving the permeance of hybrid polymer/metal-organic framework (MOF) membranes for organic solvent nanofiltration (OSN) - development of MOF thin films via interfacial synthesis
in Journal of Materials Chemistry A
Cachelin P
(2016)
Optical Acetone Vapor Sensors Based on Chiral Nematic Liquid Crystals and Reactive Chiral Dopants
in Advanced Optical Materials
Buyandelger B
(2015)
ZBTB17 (MIZ1) Is Important for the Cardiac Stress Response and a Novel Candidate Gene for Cardiomyopathy and Heart Failure.
in Circulation. Cardiovascular genetics
Burés J
(2014)
Rationalization of an unusual solvent-induced inversion of enantiomeric excess in organocatalytic selenylation of aldehydes.
in Angewandte Chemie (International ed. in English)
Burés J
(2016)
A Simple Graphical Method to Determine the Order in Catalyst.
in Angewandte Chemie (International ed. in English)
Burés J
(2016)
Explaining Anomalies in Enamine Catalysis: "Downstream Species" as a New Paradigm for Stereocontrol.
in Accounts of chemical research
Bull J
(2015)
Recent Advances in the Synthesis of 2-Substituted Oxetanes
in Synlett
Bull J
(2015)
2-Sulfinyl Oxetanes: Synthesis, Stability and Reactivity
in Synlett
Buchaca-Domingo E
(2015)
Direct Correlation of Charge Transfer Absorption with Molecular Donor:Acceptor Interfacial Area via Photothermal Deflection Spectroscopy.
in Journal of the American Chemical Society
Bruno A
(2014)
Ternary hybrid systems of P3HT-CdSe-WS2 nanotubes for photovoltaic applications.
in Physical chemistry chemical physics : PCCP
Brooks N
(2014)
Pressure effects on lipids and bio-membrane assemblies
in IUCrJ
Brooks N
(2014)
High Pressure X-ray Studies of Lipid Membranes and Lipid Phase Transitions
in Zeitschrift für Physikalische Chemie
Broncel M
(2015)
Multifunctional reagents for quantitative proteome-wide analysis of protein modification in human cells and dynamic profiling of protein lipidation during vertebrate development.
in Angewandte Chemie (International ed. in English)
Britovsek G
(2015)
Ethylene Oligomerization beyond Schulz-Flory Distributions
in ACS Catalysis
Britovsek G
(2015)
Single- and Double-Coordination Mechanism in Ethylene Tri- and Tetramerization with Cr/PNP Catalysts
in ACS Catalysis
Bresme F
(2014)
Communication: minimum in the thermal conductivity of supercooled water: a computer simulation study.
in The Journal of chemical physics
Braddock DC
(2013)
Epoxidation of bromoallenes connects red algae metabolites by an intersecting bromoallene oxide--Favorskii manifold.
in Chemical communications (Cambridge, England)
Braddock DC
(2014)
Studies towards the synthesis of halomon: asymmetric hexafunctionalisation of myrcene.
in Chemical communications (Cambridge, England)
Braddock DC
(2013)
An enantiospecific polyene cyclization initiated by an enantiomerically pure bromonium ion.
in Chirality
Braddock DC
(2014)
Proof-of-principle direct double cyclisation of a linear C15-precursor to a dibrominated bicyclic medium-ring ether relevant to Laurencia species.
in Chemical communications (Cambridge, England)
Boultwood T
(2014)
Synthesis and purification of iodoaziridines involving quantitative selection of the optimal stationary phase for chromatography.
in Journal of visualized experiments : JoVE
Boultwood T
(2015)
Studies on the synthesis of a-iodoaziridines and improved conditions for the synthesis of alkyl-a-iodoaziridines using ClMgCHI2
in Tetrahedron
Boultwood T
(2014)
Stereospecific functionalization of iodoaziridines via unstabilized aziridinyllithiums generated by iodine-lithium exchange.
in Organic letters
Bomparola R
(2014)
Lithium heterocuprates: the influence of the amido group on organoamidocuprate structures.
in Dalton transactions (Cambridge, England : 2003)
Bolognesi G
(2015)
Microfluidic generation of monodisperse ultra-low interfacial tension oil droplets in water
in RSC Advances
Billcliff PG
(2016)
OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates.
in Molecular biology of the cell
Berger RJ
(2014)
Gold(I) mediated rearrangement of [7]-helicene to give a benzo[cd]pyrenium cation embedded in a chiral framework.
in Chemical communications (Cambridge, England)
Bell A
(2020)
Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes
in Journal of Medicinal Chemistry
Beatrup D
(2014)
Polaron stability in semiconducting polymer neat films.
in Chemical communications (Cambridge, England)
Bayazit MK
(2016)
Carbon nanotube anions for the preparation of gold nanoparticle-nanocarbon hybrids.
in Chemical communications (Cambridge, England)
Barriga HM
(2015)
Pressure-temperature phase behavior of mixtures of natural sphingomyelin and ceramide extracts.
in Langmuir : the ACS journal of surfaces and colloids
Barriga HM
(2016)
The effect of hydrostatic pressure on model membrane domain composition and lateral compressibility.
in Physical chemistry chemical physics : PCCP
Barriga HM
(2015)
Temperature and pressure tuneable swollen bicontinuous cubic phases approaching nature's length scales.
in Soft matter
Barriga HM
(2014)
Droplet interface bilayer reconstitution and activity measurement of the mechanosensitive channel of large conductance from Escherichia coli.
in Journal of the Royal Society, Interface
Barriga HM
(2015)
Buffer-induced swelling and vesicle budding in binary lipid mixtures of dioleoylphosphatidylcholine:dioleoylphosphatidylethanolamine and dioleoylphosphatidylcholine:lysophosphatidylcholine using small-angle X-ray scattering and ³¹P static NMR.
in Langmuir : the ACS journal of surfaces and colloids
Barrett T
(2014)
Cascade Polyketide and Polyene Cyclizations: Biomimetic Total Synthesis of Hongoquercin B
in Journal of the American Chemical Society
Barreiro E
(2015)
HBF4-Catalysed Nucleophilic Substitutions of Propargylic Alcohols.
in European journal of organic chemistry
Baran D
(2015)
Role of Polymer Fractionation in Energetic Losses and Charge Carrier Lifetimes of Polymer: Fullerene Solar Cells
in The Journal of Physical Chemistry C
Description | Chemistry is the study and application of the science at the molecular scale. It provides some of the most basic understandings of how the world works and underpins many modern technologies. It provides both the most mundane of objects, such as the disposable cup that holds you coffee, and the most vital compounds, such as life-saving drugs. Chemistry relies on four core instrumental techniques to study molecules; Nuclear Magnetic Resonance, Mass Spectrometry, X-Ray Crystallography and molecular scale Microscopy. This grant gave the Chemistry Department at Imperial College the ability to update these facilities. These have enabled research in all areas of Chemistry, for example the building of artificial cells, the production of fuels from biomass to the development of new potential pharmaceuticals and diagnostic techniques. There are too many to list. |
Exploitation Route | There are many ways in which these results can be put to use in the wider world. |
Sectors | Aerospace, Defence and Marine,Agriculture, Food and Drink,Chemicals,Energy,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Culture, Heritage, Museums and Collections,Pharmaceuticals and Medical Biotechnology,Security and Diplomacy,Transport |
Description | Policy Briefing Document |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Author of policy briefing document: Using Carbon Dioxide |
Year(s) Of Engagement Activity | 2017 |
Description | Presentation to stakeholders |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Laura Barter was invited to the World Economic Forum in Davos to present her research investigating methods for increasing crop yields by promoting more efficient photosynthesis in the session on "Engineering Intelligent Food Systems". |
Year(s) Of Engagement Activity | 2018 |
Description | Radio Interview |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | BBC World Service's The Why Factor (8 February) on "Why is Water Exceptional?" |
Year(s) Of Engagement Activity | 2016 |
Description | Radio Interview |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Andrew Ashley interviewed on BBC Radio 4's Inside Science explaining his group's recent discovery in N2 fixation |
Year(s) Of Engagement Activity | 2016 |
Description | Schools activity |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Schools |
Results and Impact | Salters Festival of Chemistry: Annual Salters Festival. Y7 and Y8 many schools attend with their teachers to undertake two chemistry-based challenges |
Year(s) Of Engagement Activity | 2018 |
Description | Stakeholder meeting |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Laura Barter, Rudiger Wolcholski and Sarah Al-Beidh organised a Creativity and Ideas generation event for the Sainsbury's farming scholars which was also attended by Sainsbury's horticulture manager, academics from Imperial, Natural History Museum and other UK institutions. Followed by attending the Annual Sainsbury's Farming Conference to highlight the success of the Sainsbury's Farming Scholars Programme - a recent collaboration between Imperial College, AGRI-net and Sainsbury's. |
Year(s) Of Engagement Activity | 2015,2016 |
Description | UK Chemicals Stakeholder Forum. Presentation on measuring sustainability |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Policymakers/politicians |
Results and Impact | Presentation and discussion on sustainability metrics |
Year(s) Of Engagement Activity | 2016 |
Description | World Economic Forum meeting |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Prof David Klug introduced the "Hyperconnected Healthcare" panel at the World Economic Forum meeting in Dalian and participated as a panel member. |
Year(s) Of Engagement Activity | 2015 |